Clinical Trials Sponsored by Heart Research U.K.

Total 1624 results

Mayo Clinic
Florida Heart Research Institute

Recruiting

Exercise Training to Improve Cardiopulmonary Hemodynamics in Heart Failure Patients

Heart Failure | Pulmonary Hypertension

United States
Kansas City Heart Rhythm Research Foundation

Recruiting

HS Students Mandatory Universal Student Instruction in CPR Appraised Learning- Is the Mandate Working?

Sudden Cardiac Arrest

United States
Kansas City Heart Rhythm Research Foundation

Completed

Arrhythmic Manifestations and Management in Hospitalized COVID-19 Patients

Coronavirus Infections

United States
Ottawa Heart Institute Research Corporation
Medtronic

Completed

Discerning Symptomatic and Asymptomatic Episodes Pre and Post Radiofrequency Ablation of Atrial Fibrillation (DISCERN-AF)

Atrial Fibrillation

Canada
Ottawa Heart Institute Research Corporation
Bayer

Completed

Pilot Study to Evaluate Right Ventricular Function With Riociguat in CTEPH

Chronic Thromboembolic Pulmonary Hypertension

Canada
Kansas City Heart Rhythm Research Foundation

Not yet recruiting

Vascular Closure With Novel External Compression Device: The LockeT Study

Atrial Fibrillation | Hemostasis

United States
Kansas City Heart Rhythm Research Foundation

Not yet recruiting

Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry

Atrial Fibrillation | Ischemic Stroke, Acute

United States
Kansas City Heart Rhythm Research Foundation

Recruiting

Use of 4D-ICE in Conjunction With TEE for Left Atrial Appendage Closure

Stroke | Atrial Fibrillation

United States
Kansas City Heart Rhythm Research Foundation

Recruiting

Long Term Evaluation of Cardiac Arrhythmias After Transcatheter Aortic Valve Implantation -The LOCATE Registry

Aortic Stenosis | Heart Block | Atrial Fibrillation New Onset

United States
Kansas City Heart Rhythm Research Foundation

Not yet recruiting

Assessing the Predictive Value of High Frequency Algorithm of PURE EP for Low Amplitude Signal Detection

Cardiac Arrhythmias

United States
Kansas City Heart Rhythm Research Foundation

Recruiting

Comparative Analysis in Detection of Atrial Arrhythmia and ECG Quality in Three Different Insertable Cardiac Monitors

Arrhythmias, Cardiac

United States
Heart and Brain Research Group, Germany

Completed

Cognitive Outcome After Surgical and Transcatheter Aortic Valve Replacement (COSTA)

Postoperative Delirium | Postoperative Cognitive Dysfunction | Transcatheter Aortic Valve Replacement | Surgical Aortic Valve Replacement

Germany
Kansas City Heart Rhythm Research Foundation

Terminated

Accuracy of Rhythm Detection by a Wearable Smart Watch for Cardiac Arrhythmias (The WATCH-RHYTHM Study)

Atrial Fibrillation

United States
Kansas City Heart Rhythm Research Foundation

Completed

Multimodality Evaluation of LAA Leaks Arising After Incomplete LAAC: Insights From the LAA-Leak Registry

Left Atrail Appendage Closure: Peri-device Leaks

United States
Kansas City Heart Rhythm Research Foundation

Unknown

Clinical and Economic Impact of an Organized Treatment Pathway on AFib Patient Management From the ER (ER2EP)

Atrial Fibrillation | Cardiac Arrhythmia

United States
Bayside Health
Baker Heart Research Institute

Completed

Improving Metabolism With HDL Cholesterol

Diabetes | Heart Disease

Australia
AstraZeneca
Ottawa Heart Institute Research Corporation

Completed

Effects of Rosuvastatin on Aortic Stenosis Progression (ASTRONOMER)

Aortic Stenosis

Canada
Kansas City Heart Rhythm Research Foundation
Kansas City Heart Rhythm Institute

Not yet recruiting

Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry (MAVERIC)

Myocarditis | Ventricular Tachycardia (VT) | Premature Ventricular Contractions

United States
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Evaluation of a Web-based Intervention to Promote Physical Activity in Patients With Heart Disease.

Coronary Artery Disease (CAD)

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Self-directed Titrated Transdermal Nicotine Patch Versus Standard Treatment for Smoking Cessation (STEP)

Smoking Cessation

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Rt Ventricular Substrate Metabolism as a Predictor of Rt Heart Failure in Patients With Pulmonary Arterial Hypertension (RVMET)

Pulmonary Arterial Hypertension

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Reducing Cardiovascular Disease by Combining Smoking Cessation Pharmacotherapy and Behavioural Counseling (RW)

Smoking Cessation | Psychiatric Illness

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Interactive Voice Response Telephone Technology for the Treatment of Smoking in Patients With Heart Disease (IVR)

Coronary Artery Disease

Canada
U.S. Army Medical Research Acquisition Activity

Unknown

Daily Target Guided Radiation Therapy Using the Calypso 4D Localization System in Patients Who Have Had a Prostatectomy for Prostate Cancer

Prostate Cancer

United States
Kansas City Heart Rhythm Research Foundation
Kansas City Heart Rhythm Institute

Not yet recruiting

Impact of Steerable Delivery Sheaths on Successful Closure of LA A With AMULET

Stroke | Atrial Fibrillation

United States
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Canada

Recruiting

Characterization of Arrhythmia Substrate to Ablate Persistent Atrial Fibrillation (COAST-AF RCT)

Atrial Fibrillation

Canada
Kansas City Heart Rhythm Institute
Kansas City Heart Rhythm Research Foundation

Completed

DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation (STROKE-VT)

Stroke | Ventricular Tachycardia | Premature Ventricular Contraction

United States, India
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

The Efficacy and Economics of Exercise Maintenance Post-Cardiac Rehabilitation (ECOPCR)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

A Study of the Effect of Blinding in a Trial of Blood Filtration During Heart Surgery

Heart Diseases

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Endothelial Modulation for Angiogenic Therapy

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

The Efficacy and Cost-Effectiveness of Behavioral Counseling for Exercise in Men and Women Following Acute Myocardial Infarction (AMI) and Percutaneous Coronary Intervention (PCI)

Myocardial Infarction | Coronary Arteriosclerosis

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Efficacy and Cost-Effectiveness of Cost-free Pharmacotherapy for Smoking Cessation for High-risk Smokers With Cerebrovascular Disease

Cerebrovascular Disorders | Smoking Cessation

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Canada

Completed

Family Heart Health Program: Randomized, Controlled Trial (FHHP-RCT)

Coronary Heart Disease

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

CPAP Therapy in Patients With Heart Failure and Obstructive Sleep Apnea. (PET-OSA)

Heart Failure | Obstructive Sleep Apnea

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Varenicline Versus Transdermal Nicotine Patch for Smoking Cessation in Patients With Coronary Heart Disease

Coronary Heart Disease

Canada
Ottawa Hospital Research Institute
Ottawa Heart Institute Research Corporation

Completed

Cardiac MRI for Metal on Metal Hip Resurfacing (CardiacMRI)

Cardiomyopathy

Canada
Lawson Health Research Institute
Ottawa Heart Institute Research Corporation

Terminated

Using IVR to Maintain ACS Patients on Best Practice Guidelines (IVR-ACS BPG)

Medication Adherence | Acute Coronary Syndrome

Canada
Ottawa Hospital Research Institute
Ottawa Heart Institute Research Corporation

Completed

Smoking Cessation With the Ottawa Model and SmartCard in Out-patient Respirology Clinic Setting (Quit&Win)

Smoking Cessation

Canada
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Completed

Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia (ALPS)

Cardiac Arrest

United States, Canada
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Completed

Continuous Chest Compressions vs AHA Standard CPR of 30:2 (CCC)

Out of Hospital Cardiac Arrest

United States, Canada
Medical Research Council
Cancer Research UK

Unknown

ICON8: Weekly Chemotherapy in Ovarian Cancer (ICON8)

Ovarian Cancer

United Kingdom
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Completed

Prehospital Tranexamic Acid Use for Traumatic Brain Injury (TXA)

Traumatic Brain Injury

United States, Canada
Cancer Research UK
AstraZeneca

Completed

A Phase I Trial of AZD3965 in Patients With Advanced Cancer

Adult Solid Tumor | Burkitt Lymphoma | Diffuse Large B Cell Lymphoma

United Kingdom
Cancer Research UK, Glasgow

Completed

Combination Chemotherapy After Surgery in Treating Patients With High-Risk Stage II or Stage III Colorectal Cancer

Colorectal Cancer

United Kingdom
Cancer Research UK
AstraZeneca

Completed

A Phase I Trial of Vandetanib (AZD6474) and Selumetinib (AZD6244) for Solid Tumours Including Non Small Cell Lung Cancer (VanSel-1)

Cancer | Non Small Cell Lung Cancer

United Kingdom
Macmillan Research Group UK

Completed

Impact of Women's Empowerment Program for Abused Pregnant Women

Abuse Physical Battered Woman Syndrome

India
Carelon Research
National Heart, Lung, and Blood Institute (NHLBI); Jarvik Heart, Inc.

Active, not recruiting

Pumps for Kids, Infants, and Neonates (PumpKIN)

Pediatric Heart Failure

United States
Mayo Clinic
Miami Heart Research Institute Inc.

Not yet recruiting

HTN App for HTN Control and Cardiovascular Health Among African-Americans

Hypertension

United States
Mayo Clinic
Ottawa Heart Institute Research Corporation

Recruiting

Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion (CAPITAL-RAPTOR)

Radial Artery Occlusion

United States
Ottawa Heart Institute Research Corporation
GE Healthcare

Recruiting

Multi-Center Evaluation of Feasibility of SPECT Measurement of Myocardial Blood Flow and Reserve

Coronary Artery Disease

Canada, Germany, Belgium, Japan, Singapore

Clinical Trials Sponsored by Heart Research U.K.

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