Clinical Trials Sponsored by Institut Pierre Richet

Total 344 results

National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZT

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

Dideoxycytidine ( Ro 24-2027 ) A Randomized, Open-Label, Comparative Study of Dideoxycytidine ( ddC ) Versus Zidovudine ( AZT ) in Patients With AIDS or Advanced ARC Who Have Received Long-Term AZT Therapy.

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Randomized Study of Activity, Safety, and Tolerance of Oral Ro 24-7429 (Tat Antagonist) in Patients With HIV Infection

HIV Infections

United States
Institut für Klinische Krebsforschung IKF GmbH...
Roche Pharma AG

Recruiting

Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness (DANTE)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Germany, Switzerland
Peter Liu
Ottawa Heart Institute Research Corporation; Roche Diagnostics; Genome Canada

Recruiting

Biomarker Guided Discharge of Heart Failure Patients (RADAR)

Heart Failure; With Decompensation

Canada
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV

Gastrointestinal Diseases | HIV Infections | Cytomegalovirus Retinitis

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir

HIV Infections | Cytomegalovirus Retinitis

United States
H. Lee Moffitt Cancer Center and Research Institute
Roche Pharma AG

Terminated

Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)

Adenocarcinoma | Colon Cancer

United States
Hoosier Cancer Research Network
Sanofi; Hoffmann-La Roche; Walther Cancer Institute

Completed

Capecitabine and Oxaliplatin in Treating Patients With Metastatic Breast Cancer

Metastatic Breast Cancer

United States
Hoosier Cancer Research Network
Sanofi; Hoffmann-La Roche; Walther Cancer Institute

Terminated

Docetaxel and Capecitabine for First Line Treatment of Metastatic Squamous Cell Carcinoma of the Head & Neck

Head and Neck Cancer

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Hoffmann-La Roche

Completed

Comparison of Ro 31-8959 Plus Zidovudine (AZT) Versus AZT Plus Zalcitabine (ddC) Versus Ro 31-8959 Plus AZT Plus ddC

HIV Infections

United States
Swiss Tropical & Public Health Institute
University of Applied Sciences and Arts Northwestern Switzerland; Terre des... and other collaborators

Recruiting

Hands4Health: A Multi-component Intervention on Hand Hygiene & Well-being in Schools in Nigeria & Palestine (H4H) (H4H)

Hand Hygiene | Well-Being | Handwashing Behaviour

Nigeria, Palestinian Territory, occupied
Centre Hospitalier Universitaire de Pointe-a-Pitre
Institut National de la Santé Et de la Recherche Médicale, France

Recruiting

Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression. (KP-CARAIBES)

Adenocarcinoma | Neoplasm Metastasis | Prostatic Neoplasm | Neoplasm Recurrence

France, Guadeloupe
Rosa Cabanas Valdés
Corporacion Parc Tauli; Institut Investigacio Sanitaria Pere Virgili

Completed

"Core Stability" Exercises to Improve Sitting Balance in Stroke Patients (Fisionet)

Stroke | Cerebrovascular Accident | Cerebral Stroke

Spain
Institut Investigacio Sanitaria Pere Virgili
Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders

Completed

Characterization of High Density Lipoprotein (HDL) in Type 2 Diabetes (T2D) After Fenofibrate or Niacin Treatment (LOWHDL)

Type 2 Diabetes Mellitus | Dyslipidemia

Spain
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy... and other collaborators

Completed

TAA-Specific CTLS for Solid Tumors (TACTASOM)

Rhabdomyosarcoma

United States
NSABP Foundation Inc
Hoffmann-La Roche; Genentech, Inc.; International Drug Development Institute

Terminated

Study of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the Colon

Colorectal Neoplasms

United States
The Netherlands Cancer Institute
Merck Sharp & Dohme LLC; Roche Pharma AG; AstraZeneca

Unknown

Lung Cancer Early Molecular Assessment Trial (LEMA)

Carcinoma, Non-Small-Cell Lung

Netherlands
NSABP Foundation Inc
Hoffmann-La Roche; Genentech, Inc.; International Drug Development Institute

Completed

Therapy With Bevacizumab (BEV), Doxorubicin, and Cyclophosphamide Followed by BEV, Docetaxel, and Capecitabine Before Surgery Followed by BEV Alone After Surgery for Women With Locally Advanced Breast Cancer

Breast Cancer

United States
Ottawa Hospital Research Institute
Sanofi; Hoffmann-La Roche; Ottawa Regional Cancer Foundation

Unknown

IXO (Irinotecan, Xeloda, Oxaliplatin) in Rectal Cancer (IXOr)

Rectal Cancer

Canada
Puerta de Hierro University Hospital
Instituto de Salud Carlos III; Ministerio de Economía y Competitividad, Spain; Gammera Nest Technology Company

Unknown

The Secret Trail of Moon (Serious Videogame) and Chess on ADHD: a Clinal Trial

Attention Deficit Disorder With Hyperactivity

Spain
Materno-Perinatal Hospital of the State of Mexico
Hospital General "Dr. Darío Fernández Fierro"; National Institute of Neurology...

Terminated

Manganese in Women With Encephalopathy

Hepatic Encephalopathy

Mexico
Centre Hospitalier Universitaire de Besancon
Roche Pharma AG; National Cancer Institute, France

Active, not recruiting

Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL) (VolATIL)

Cervical Cancer | Squamous Cell Carcinoma of the Head and Neck | Anal Canal Cancer

France
Cancer Institute and Hospital, Chinese Academy...
Hoffmann-La Roche

Unknown

Capecitabine (NX) Versus Docetaxel Plus Capecitabine (TX) as 1-line Chemotherapy on Metastatic Breast Cancer (MBC)

Carcinoma, Invasive Ductal, Breast

China
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI); Rocket Pharma Limited

Active, not recruiting

Gene Therapy for Fanconi Anemia

Fanconi Anemia

United States
Instituto de Investigación Marqués de Valdecilla
Hospital General Universitario Gregorio Marañon; Hospital Universitario Ramon... and other collaborators

Unknown

Portal Hypertension in Non-alcoholic Fatty Liver Disease: Association With Cardiovascular Risk and Identification of Non-invasive Biomarkers (THESIS) (THESIS)

Fatty Liver Disease
Institut für Diabetes-Technologie Forschungs- und...
Roche Diagnostics

Completed

Assessment of Blood Glucose Monitoring Systems - Evaluation of Oxygen Dependency (IDT-1326-IU)

Diabetes

Germany
Universidad de Granada
Institut d'Investigació Biomèdica de Bellvitge; University of Seville; National... and other collaborators

Recruiting

Pro-Vegetarian Diets, Microbial/Metabolite Profiles and Cancer (MIVECA)

Cancer | Dietary Habits | Metabolic Disease | Food Habits | Nutrition, Healthy

Spain
National Cancer Centre, Singapore
Hoffmann-La Roche; Sirtex Medical; Singapore Clinical Research Institute

Recruiting

Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients (STRATUM)

Locally Advanced Hepatocellular Carcinoma

Korea, Republic of, Singapore
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Glaxo Wellcome

Completed

A Randomized Phase II Study of Two Doses of Interferon Alfa-2a (IFN Alfa-2a) in Combination With Zidovudine (AZT) and Dideoxycytidine (ddC) Versus AZT and ddC Only in Patients With HIV Infection and Less Than 400 CD4 Cells/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Glaxo Wellcome

Completed

A Randomized, Double Blind, Comparative Study of Dideoxycytidine (ddC) Alone or ddC/AZT Combination Versus Zidovudine (ZDV) Alone in Patients With HIV Infection Who Have Received Prior ZDV Therapy

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Astra USA

Completed

A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir

HIV Infections | Cytomegalovirus Retinitis

United States
National Institute of Diabetes and Digestive and...
Roche Pharma AG

Completed

PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis C

Chronic Hepatitis C

United States
Ottawa Hospital Research Institute
Sanofi; Pfizer; Hoffmann-La Roche; Ottawa Regional Cancer Foundation

Terminated

A Phase I/II Study of IXO With Bevacizumab in Patients With Metastatic Colorectal Cancer (IXO+A)

Metastatic Colorectal Cancer

Canada
National Institute of Diabetes and Digestive and...
Hoffmann-La Roche

Completed

Effectiveness of Brief Counseling for Weight Management

1. Obesity

United States
Barcelona Institute for Global Health
Centro de Investigação em Saúde de Manhiça; Medicines for Malaria Venture; University... and other collaborators

Recruiting

MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention (MULTIPLY)

Malaria

Mozambique, Sierra Leone, Togo
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Schering-Plough

Completed

The Safety and Effectiveness of Ganciclovir Used Alone or in Combination With Granulocyte-Macrophage Colony Stimulating Factor in the Treatment of Cytomegalovirus (CMV) of the Eye in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Glaxo Wellcome

Completed

The Safety of Zidovudine Plus Interferon-Alpha in HIV-Infected Children

HIV Infections

United States, Puerto Rico
University of Calgary
Canadian Institutes of Health Research (CIHR); Roche Pharma AG

Completed

Pegylated Interferon Plus Ribavirin in the Treatment of Active and Past Intravenous Drug Users Infected With Hepatitis C

Hepatitis c

Canada
Bryan Denny
National Institute on Aging (NIA)

Recruiting

Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease

Stress | Emotions | Emotion Regulation | Psychological | Caregivers | Psychophysiology

United States
Rachel Sanborn
AstraZeneca; Providence Cancer Center, Earle A. Chiles Research Institute

Active, not recruiting

Durvalumab Followed by Chemoradiation and Consolidation Durvalumab for Stage III Non-small Cell Lung Cancer

Lung Cancer | Non-small Cell Carcinoma

United States
Bryan Denny
National Institute on Aging (NIA)

Recruiting

Neural Mechanisms of Enhancing Emotion Regulation in Bereaved Spouses

Depressive Symptoms | Emotions | Grief | Bereavement | Affect

United States
Fundació Institut de Recerca de l'Hospital de la...
Roche Diagnostics

Completed

¿Can mySugr App Improve Knowledge and Self-management of People With Type 1 Diabetes Mellitus?

Diabetes Mellitus, Type 1

Spain
Institut für Klinische Krebsforschung IKF GmbH...
Roche Pharma AG; Thoraxklinik-Heidelberg gGmbH

Recruiting

NeoTRACK - Dissection of IO Efficacy in NSCLC by Longitudinal tracKing

Non-small Cell Lung Cancer

Germany
Gabi Chiorean, MD
Pfizer; Roche Pharma AG; Walther Cancer Institute

Terminated

Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer

Rectal Cancer

United States
Instituto Oncológico Dr Rosell
Roche Pharma AG; Fundacion Clinic per a la Recerca Biomédica

Active, not recruiting

Combination of Atezolizumab With Dendritic Cell Vaccine in Patients With Lung Cancer (VENEZO-LUNG)

Extensive-stage Small Cell Lung Cancer

Spain
Binghe Xu
Hoffmann-La Roche

Unknown

Capecitabine Maintenance Therapy Following Capecitabine Combined With Docetaxel in Treatment of mBC (CAMELLIA)

Skin Diseases | Neoplasms by Site | Breast Neoplasms | Breast Diseases | Neoplasm Metastasis

China
Boston University
Fogarty International Center of the National Institute of Health; Right to...

Completed

Intervention Zambia Rural L&D Infection Study

Neonatal Infection | Postpartum Infection

Zambia
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Hoffmann-La Roche

Completed

A Prospective, Randomized, Open-Label, Comparative Trial of Dideoxyinosine (ddI) Versus Dideoxycytidine (ddC) in HIV-Infected Patients Who Are Intolerant of or Who Have Failed Zidovudine (AZT) Therapy

HIV Infections

United States

Clinical Trials Sponsored by Institut Pierre Richet

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zimbabwe

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations