Clinical Trials Sponsored by Laboratory Corporation of America

Total 81 results

GlaxoSmithKline
PPD; Laboratory Corporation of America

Not yet recruiting

Study to Evaluate the Effect of Bepirovirsen on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers

Hepatitis B

United States
Sequenom, Inc.
Laboratory Corporation of America

Recruiting

The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)

United States
Sequenom, Inc.
Laboratory Corporation of America

Completed

Impact of Guided Care With the Vectra Multi-biomarker Disease Activity (MBDA) Blood Test (CareFirst)

Rheumatoid Arthritis

United States
GE Healthcare
Laboratory Corporation of America

Not yet recruiting

Study to Evaluate Safety and Dosimetry of [18F]GEH121224 in Patients With Locally Advanced or Metastatic Breast Cancer

Breast Cancer

United States
GE Healthcare
Laboratory Corporation of America

Completed

Study to Determine Safety and Dosage of OPTISON in Pediatric Participants

Transthoracic Echocardiography | Suspected or Known Structural or Functional Cardiac Abnormality

United States
Albany Medical College
Laboratory Corporation of America

Completed

Anastrazole and Clomiphene to Evaluate Hypogonadal Symptoms and Erectile Function (CAP)

Hypogonadism, Male
Cascade Pharmaceuticals, Inc
Laboratory Corporation of America

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of CS0159 in Subjects With NASH

Nonalcoholic Steatohepatitis (NASH)

United States
Pharmacosmos A/S
Laboratory Corporation of America; BioStata

Withdrawn

IV Iron Treatment of Restless Legs Syndrome

Restless Legs Syndrome
Lytix Biopharma AS
Laboratory Corporation of America; OWL

Active, not recruiting

Intratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced Melanoma (ATLAS-IT-05)

Advanced Melanoma

United States, Spain, France, Norway
Nuance Pharma (shanghai) Co., Ltd
Laboratory Corporation of America

Recruiting

A Study to Evaluate the Efficacy and Safety of Ensifentrine for 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

China
University of Pennsylvania
Sequenom, Inc/Laboratory Corporation of America Holdings

Completed

Clinical Performance of NIPT in Multiple Gestation Pregnancies

Trisomy 21 in Fetus

United States
Pharmacosmos A/S
Laboratory Corporation of America; BioStata; ClinStar, LLC

Completed

IDA-01 A Randomised, Open-Label, Comparative Study of Intravenous Iron Isomaltoside 1000 (Monofer®) and Iron Sucrose (Provide)

Iron Deficiency Anaemia

United States
Hoffmann-La Roche
PPD; Laboratory Corporation of America; Illingworth Research Group

Active, not recruiting

A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab (SOPRANINO)

Multiple Sclerosis | Clinically Isolated Syndrome

United States, Spain, United Kingdom, Germany
Hoffmann-La Roche
PPD; Laboratory Corporation of America; Illingworth Research Group

Active, not recruiting

A Study Evaluating B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy (MINORE)

Multiple Sclerosis | Clinically Isolated Syndrome

United States, Spain, Switzerland, France, Germany
University of North Carolina, Chapel Hill
Laboratory Corporation of America; Kerr Drug

Completed

Implementation of a Personalized Medicine (Pharmacogenomics) Service in a Community Pharmacy

Myocardial Infarction | Stroke | Transient Ischemic Attack

United States
University of Alabama at Birmingham
Laboratory Corporation of America; Cahaba Medical Care Foundation

Recruiting

Self-Collection of the Pap Smear as Agency: A Novel Way to Improve Refractory Low Cervical Cancer Screening Rates in Rural Alabama (Pap)

Cervical Cancer

United States
University of North Carolina, Chapel Hill
Laboratory Corporation of America; IntraPump Infusion Systems

Completed

Once Weekly Subcutaneous Ports for the Administration of Anticoagulants

Venous Thromboembolism

United States
Treos Bio Zrt
Mayo Clinic; University of Pisa; PPD; Laboratory Corporation of America; ImmunXperts...

Completed

PolyPEPI1018 Vaccine and CDx for the Treatment of Metastatic Colorectal Cancer (OBERTO) (OBERTO)

Colorectal Cancer

United States, Italy
Pharming Technologies B.V.
Laboratory Corporation of America; CMIC Co, Ltd. Japan; Axial Biotech, Inc

Recruiting

An Open-Label Study to Assess the Safety & Efficacy of Leniolisib in Japanese Patients With APDS

APDS Gene Mutation

Japan
Olympus Corporation of the Americas

Recruiting

A Randomized, International Study to Assess the Safety of iTind Compared to UroLift (MT-08)

Benign Prostatic Hyperplasia (BPH)

United States, United Kingdom, Canada
Olympus Corporation of the Americas

Completed

Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function (EMPROVE)

Emphysema

United States, Canada
Olympus Corporation of the Americas

Terminated

ANET Electrosurgery Applicator Pilot Evaluation Study

Lung Cancer | Lung Cancer Metastatic

United States, Canada
Olympus Corporation of the Americas

Completed

The Performance of the SOLTIVE Laser System for Laser Lithotripsy in Kidney or Ureteral Stones

Kidney Stone | Ureteral Stone

United States, Portugal, Denmark
Olympus Corporation of the Americas

Recruiting

STRIVE Post-Market Registry Study

Emphysema

United States
Laminar Pharmaceuticals
Laboratory Corporation of America; Northern Institute for Cancer Research,... and other collaborators

Active, not recruiting

LAM561 With RT and TMZ for Adults With Glioblastoma (CLINGLIO)

Glioblastoma Multiforme | Primary Glioblastoma

Spain, Italy, United Kingdom, France, Israel
Olympus Corporation of the Americas

Terminated

Spiration Valves Against Standard Therapy (VAST)

Pulmonary Air Leaks

United States
Drug Delivery Company, LLC DBA Akyso Pharmaceuticals
National Institute on Drug Abuse (NIDA); Laboratory Corporation of America; Cognitive...

Not yet recruiting

A Phase 1, Placebo-controlled, Single-Ascending-Dose, Study of BIOPIN 6 in Healthy Adults

Opioid Use Disorder
Exact Sciences Corporation
Labcorp Corporation of America Holdings, Inc

Recruiting

First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United Kingdom, Spain, Italy, Israel
Medco Health Solutions, Inc.
Mayo Clinic; International Business Machines (IBM); Laboratory Corporation of... and other collaborators

Completed

The Clinical and Economic Impact of Pharmacogenomic Testing for Tamoxifen Metabolism in Postmenopausal Women Receiving Tamoxifen for Prevention of Recurrent Breast Cancer (MHSLabCorp1)

Breast Neoplasms | Tamoxifen

United States
Sequenom, Inc.
Labcorp Corporation of America Holdings, Inc

Completed

Evaluation of the Labcorp COVID-19+Flu+RSV Test Home Collection Kit

Influenza A | RSV Infection | COVID-19 Respiratory Infection | Influenza Type B

United States
Olympus Corporation of the Americas
Geisinger Clinic

Completed

The EUS ShearWave Elastography Liver Fibrosis Study

Liver Fibroses

United States
Aurinia Pharmaceuticals Inc.
Labcorp Corporation of America Holdings, Inc

Not yet recruiting

Long-Term Voclosporin Treatment in Adolescent Subjects With Lupus Nephritis (VOCAL-EXT)

Adolescent Lupus Nephritis

United States
Cellivery Therapeutics, Inc.
Labcorp Corporation of America Holdings, Inc

Suspended

iCP-NI - Safety, Tolerability, Pharmacokinetic, and Immunogenicity Study in Healthy Male and Female Subjects

Healthy Volunteers

United States
Olympus Corporation of the Americas
Unity Health Toronto

Completed

The BlackBox Study

Laparoscopic Roux-en-y Gastric Bypass

Canada
Olympus Corporation of the Americas
International Urogynecology Associates

Completed

Laparoscopic Three-dimensional Versus Two-dimensional Sacral Colpopexy and Paravaginal Repair

Pelvic Organ Prolapse | Cystocele

United States
Y-mAbs Therapeutics
Invicro; Labcorp Corporation of America Holdings, Inc

Withdrawn

131I-omburtamab Delivered by Convection-Enhanced Delivery in Patients With Diffuse Intrinsic Pontine Glioma

DIPG
Vifor (International) Inc.
Labcorp Corporation of America Holdings, Inc

Completed

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemia (VITHAL)

Beta-Thalassemia | Non-transfusion-dependent Thalassemia

Greece, Israel, Italy, Lebanon, Thailand
Shanghai EpimAb Biotherapeutics Co., Ltd.
Labcorp Corporation of America Holdings, Inc

Recruiting

EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

Neoplasms | Neoplasm Metastasis | Metastatic Gastrointestinal Carcinoid Tumor

United States, China
Shanghai EpimAb Biotherapeutics Co., Ltd.
Labcorp Corporation of America Holdings, Inc

Not yet recruiting

EMB-01 in Combination With Osimertinib in Patients With EGFR Mutant Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Advanced Lung Non-Small Cell Carcinoma | EGFR Mutation-Related Tumors

United States, China
Bostwick Laboratories
Prostate Institute of America; Community Memorial HealthCenter; HemaCare Corporation

Terminated

Safety Study of Autologous Dendritic Cells Injected Into the Prostate After Cryoablation for Advanced Prostate Cancer (CRITICAL)

Prostate Cancer

United States
Christopher Marshall
Olympus Corporation of the Americas

Completed

Study of Early Endocapsule (EC) in Clinical Decision Unit Versus Standard of Care Work-up for GI Bleeding

Melena | Hematemesis | Gastro Intestinal Bleeding

United States
Ministry of Health, Malaysia
Baxter Healthcare Corporation; Fresenius Medical Care North America

Completed

Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD.

Chronic Renal Failure

Malaysia
Erica Teixeira
Tokuyama Dental Corporation

Active, not recruiting

Esthetics of Dental Composite and Adhesive System

Cavities of Teeth

United States
The University of Texas Health Science Center at...
National Cancer Institute (NCI); Wake Forest University Health Sciences; Arizona... and other collaborators

Recruiting

Wellness App for Sleep Disturbance in Hematological Cancer Patients (Heme)

Depression | Inflammation | Cancer | Fatigue | Anxiety | Sleep Disturbance

United States
Eli Lilly and Company
University of Colorado, Denver; Quintiles, Inc.; PPD; Parexel; Laboratory Corporation... and other collaborators

Completed

First-line Treatment of Patients With Stage IV Nonsquamous Non-Small Cell Lung Cancer With Necitumumab (IMC-11F8) and Pemetrexed-Cisplatin (INSPIRE)

Non Small Cell Lung Cancer

Belgium, Brazil, Russian Federation, United Kingdom, Australia, Germany, Hungary, Italy, Romania, United States, Austria, Canada, Croatia, France, Greece, Poland, Portugal, Slovakia, South Africa, Spain
Eli Lilly and Company
University of Colorado, Denver; PPD; Parexel; ICON Clinical Research; Laboratory... and other collaborators

Active, not recruiting

First-line Treatment of Participants With Stage IV Squamous Non-Small Cell Lung Cancer With Necitumumab and Gemcitabine-Cisplatin (SQUIRE)

Non Small Cell Lung Cancer

United States, Belgium, Brazil, Russian Federation, Serbia, Spain, United Kingdom, Germany, Australia, Hungary, Italy, Romania, Austria, Croatia, France, Greece, Poland, Portugal, Slovakia, South Africa, Philippines, Canada, Korea,... and more
The National Brain Mapping Laboratory (NBML)
Neuroelectrics Corporation; Leibniz-Institut für Arbeitsforschung; Zanjan University...

Completed

Optimizing tDCS Protocol for Clinical Use in Major Depressive Disorder

Depressive Disorder | Cognitive Impairment | Psychiatric Disorder

Iran, Islamic Republic of
Weill Medical College of Cornell University
King Systems Corporation; KARL STORZ Endoscopy-America, Inc.

Completed

Comparison Study in Adult Surgical Patients of 5 Airway Devices

Intubation | Laryngoscopy
AstraZeneca
Laboratory Corporation of America; Medidata Solutions; IQVIA RDS Inc.; Calyx; Thermo... and other collaborators

Recruiting

Endoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis. (EE)

Erosive Esophagitis

United States, Italy, Belgium, Vietnam, Spain, Portugal, Russian Federation, Argentina, Greece, Australia, Lithuania
AstraZeneca
Medidata Solutions; ERT: Clinical Trial Technology Solutions; Calyx; Labcorp Corporation...

Completed

Patient Palatability and Preference of 3 Potassium Binders in Patients With Chronic Kidney Disease and Hyperkalaemia (APPETIZE)

Chronic Kidney Disease + Hyperkalaemia +/- Heart Failure

Italy, Spain, Canada, France, United States, Sweden

Clinical Trials Sponsored by Laboratory Corporation of America

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