Clinical Trials Sponsored by MRC/UVRI and LSHTM Uganda Research Unit

Total 45 results

MRC/UVRI and LSHTM Uganda Research Unit

Unknown

HIV PrEP Priming of Immune Effectors (PREPPIE)

HIV-1 Infections

Uganda
MRC/UVRI and LSHTM Uganda Research Unit

Recruiting

Safety and Immunogenicity of LNP-nCOV saRNA-02 Vaccine Against SARS-CoV-2, the Causative Agent of COVID-19 (COVAC-Uganda)

COVID-19

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Janssen Pharmaceuticals

Recruiting

Improving HIV-1 Control in Africa With Long Acting Antiretrovirals (IMPALA)

HIV-1-infection

South Africa, Kenya, Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Medical Research Council

Unknown

Cotrimoxazole Prophylaxis Cessation Study Among Stabilized HIV-Infected Adult Patients on HAART in Entebbe, Uganda (CCS)

HIV Infections

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Ministry of Health, Uganda

Recruiting

Addressing Medium- to Long-term EBOLA Associated Psychological Distress and Psychosocial Problems in Central Uganda (Ebola+D)

Ebola Virus Disease

Uganda
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Completed

Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents (TB036)

Tuberculosis

Uganda
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Completed

A Study to Assess the New Candidate Rift Valley Fever Virus Vaccine in Healthy Adults

Rift Valley Fever | RVF

Uganda
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Active, not recruiting

Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV

Malaria

Uganda
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Completed

EMaBS TB Vaccine Study

Safety | Immunogenicity

United Kingdom, Uganda
MRC/UVRI and LSHTM Uganda Research Unit
International AIDS Vaccine Initiative

Recruiting

Feasibility of Identifying, Enrolling and Following Acute and Early HIV-1 Infected Individuals. (KILGORIS)

Acute Human Immunodeficiency Virus Type I Infection

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
London School of Hygiene and Tropical Medicine

Completed

The Effectiveness of a Counselling Intervention on the Uptake of HIV Care Services Among HIV Infected Patients in Uganda

HIV

Uganda
Centers for Disease Control and Prevention
MRC/UVRI and LSHTM Uganda Research Unit; Ministry of Health, Uganda

Unknown

A Clinical Trial to Evaluate the Safety and Efficacy of Ciprofloxacin in the Treatment of Plague in Humans

Plague

Uganda
St George's, University of London
MRC/UVRI and LSHTM Uganda Research Unit; MU-JHU CARE

Active, not recruiting

Serosurveillance Study of Maternally Derived Anti-GBS Antibody (ProGreSs)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

Uganda
St George's, University of London
MRC/UVRI and LSHTM Uganda Research Unit; MU-JHU CARE

Completed

Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital (PREPARE)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

Uganda
London School of Hygiene and Tropical Medicine
MRC/UVRI and LSHTM Uganda Research Unit; Makerere University

Completed

Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa (OMWaNA)

Preterm Infant | Hypothermia, Newborn | Kangaroo Mother Care | Death; Neonatal

Uganda
Centers for Disease Control and Prevention
MRC/UVRI and LSHTM Uganda Research Unit; Ministry of Health, Uganda; Infectious...

Unknown

Immunogenicity of Fractional One-fifth and One-half Doses of Yellow Fever Vaccine Compared to Full Dose in Children 9-23 Months Old

Yellow Fever
Leiden University Medical Center
MRC/UVRI and LSHTM Uganda Research Unit; Texas Tech University Health Sciences...

Not yet recruiting

Sm-p80 Schistosomiasis Challenge Study

Schistosomiasis | Schistosoma Mansoni
EuroVacc Foundation
Centre Hospitalier Universitaire Vaudois; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Evaluation of the Effect of Late Boost on HIV-uninfected Vaccines From EV06 Trial

HIV/AIDS

Uganda
Yaounde Central Hospital
University of Exeter; University of Yaounde 1; MRC/UVRI & LSHTM Uganda Research...

Recruiting

Characteristics of Young-onset Diabetes in Sub-Saharan Africa (YODA) Study (YODA)

Type 1 Diabetes | Diabetes, Autoimmune

Tanzania, Cameroon, South Africa, Uganda
Johns Hopkins Bloomberg School of Public Health
MRC/UVRI and LSHTM Uganda Research Unit; Rakai Health Sciences Program

Completed

Enhanced Provision of Male Circumcision (MC) for HIV Prevention, Rakai, Uganda

Neonatal Male Circumcision
MRC/UVRI and LSHTM Uganda Research Unit
Karolinska Institutet; University of California, San Francisco; European and... and other collaborators

Recruiting

Improving HIV Prevention Among Adolescent Girls and Young Women (AGYW) in Uganda (PeerPREP)

HIV-1-infection

Uganda
London School of Hygiene and Tropical Medicine
MRC/UVRI and LSHTM Uganda Research Unit; World Health Organization; Makerere... and other collaborators

Completed

Menstrual Health Interventions and School Attendance Among Ugandans (MENISCUs-2)

Menstrual Health Intervention

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Department for International Development, United Kingdom; University of Exeter and other collaborators

Recruiting

Identification and Characterization of Diabetes in Low-resource Populations (DOP)

Diabetes

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Epicentre, Paris, France.; Janssen Pharmaceutica N.V., Belgium; Coalition for... and other collaborators

Completed

ZEBOVAC (Ebola Vaccine Trial, Ad26.ZEBOV/MVA-BN-Filo)

Ebola Virus Disease

Uganda
EuroVacc Foundation
Medical Research Council; Centre Hospitalier Universitaire Vaudois; MRC/UVRI... and other collaborators

Completed

Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS (EV06)

HIV/AIDS

Uganda
London School of Hygiene and Tropical Medicine
Imperial College London; MRC/UVRI and LSHTM Uganda Research Unit; University...

Completed

The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis (HCBV)

HIV | Bacterial Vaginosis

Uganda
University of Oxford
KEMRI-Wellcome Trust Collaborative Research Program; Institut Pasteur; MRC/UVRI... and other collaborators

Completed

Non- Inferiority Fractional-doses Trial for Yellow Fever Vaccine (NIFTY)

Yellow Fever

Kenya, Uganda
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); MRC/UVRI and... and other collaborators

Completed

Impact of Peer Health Workers and Mobile Phones on HIV Care

HIV Infections
University of California, San Francisco
National Institute of Mental Health (NIMH); MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

A Cognitive Behavioral And Structural HIV Prevention Intervention for Young Ugandan Sex Workers (ZETRA)

Sexually Transmitted Infection

Uganda
Wawer, Maria J., M.D.
Johns Hopkins Bloomberg School of Public Health; MRC/UVRI and LSHTM Uganda... and other collaborators

Unknown

Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community

HIV Infections | Sexually Transmitted Diseases | Papillomavirus Infections | Gonorrhea | Chlamydia Infections | Syphilis | Genital Herpes | Bacterial Vaginosis

Uganda
Makerere University
MRC/UVRI and LSHTM Uganda Research Unit; Ministry of Health, Uganda; Epicentre; Makerere University Lung Institute and other collaborators

Not yet recruiting

Solidarity/Tokomeza Ebola Trial (TOKOMEZA)

Sudan Ebola Virus Vaccines
London School of Hygiene and Tropical Medicine
Guy's and St Thomas' NHS Foundation Trust; Indian Institute of Public Health... and other collaborators

Active, not recruiting

Gestational Diabetes in Uganda and India Improving Screening and Self-management (GUIDES)

Gestational Diabetes

Uganda, India
University of California, San Francisco
London School of Hygiene and Tropical Medicine; National Institute of Mental... and other collaborators

Completed

Improving Uptake and Adherence to HIV Prevention Services With Pre-exposure Prophylaxis (PrEP), HIV Self- Testing and Adherence Support for Very High Risk HIV-negative Young Women Aged 15-24 in Kampala, Uganda (POPPi)

HIV/AIDS

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Karolinska Institutet; Amsterdam Institute for Global Health and Development; University of Rwanda and other collaborators

Recruiting

East Africa Point of Care Viral Load Study (EAPoC-VL)

HIV | Viral Load | Point of Care Monitoring

Kenya, Uganda
University of California, San Francisco
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Adjunctive Linezolid for the Treatment of Tuberculous Meningitis (ALTER)

Tuberculosis, Meningeal

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
London School of Hygiene and Tropical Medicine; Assistance Publique - Hôpitaux... and other collaborators

Not yet recruiting

Implementing Oral (Event-driven and Daily) and Long-acting Pre-Exposure Prophylaxis in Mobile Men in Sub-Saharan Africa (MOBILEMEN)

HIV
Makerere University
MRC/UVRI and LSHTM Uganda Research Unit; Makerere University Lung Institute; Directorate... and other collaborators

Recruiting

Clinical Trial of Natural Therapeutics for COVID-19 and Other Acute Respiratory Viral Infections (CONAT)

Acute Respiratory Infection

Uganda
National Institute of Allergy and Infectious Diseases...
MRC/UVRI and LSHTM Uganda Research Unit; Fogarty International Center of the... and other collaborators

Completed

Safety and Effectiveness of the Vaccine ALVAC-HIV vCP205 in HIV-Negative Adult Volunteers in Uganda

HIV Infections

Uganda
St George's, University of London
Assistance Publique - Hôpitaux de Paris; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Recruiting

Serocorrelate of Protection Against GBS (PREPARE WP3)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

France, Italy, Malawi, Netherlands, Uganda, United Kingdom
University of Oxford
Imperial College London; KEMRI-Wellcome Trust Collaborative Research Program; University of Nairobi and other collaborators

Active, not recruiting

A Study to Test Three Experimental HIV Vaccines in Healthy Adults. (HIV-CORE 006)

HIV-1-infection

Kenya, Uganda, Zambia
Wits Health Consortium (Pty) Ltd
London School of Hygiene and Tropical Medicine; King's College London; Karolinska... and other collaborators

Completed

The CHAPS Trial: Combined HIV Adolescent PrEP and Prevention (CHAPS)

HIV/AIDS

South Africa
University College, London
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Active, not recruiting

Long-Acting Treatment in Adolescents (LATA) (LATA)

HIV Infections | Hiv | HIV-1-infection | Paediatric Human Immunodeficiency Virus Infection

Uganda, Zimbabwe, Kenya, South Africa
University of Oxford
European and Developing Countries Clinical Trials Partnership (EDCTP); Medical...

Recruiting

A Study to Assess the Experimental Malaria Vaccines RH5.2-VLP and R21

Malaria, Plasmodium Falciparum

Gambia
MRC/UVRI and LSHTM Uganda Research Unit
King's College London; Karolinska Institutet; Gilead Sciences; Imperial College... and other collaborators

Enrolling by invitation

A Combination Efficacy Study in Africa of Two DNA-MVA-Env Protein or DNA-Env Protein HIV-1 Vaccine Regimens With PrEP (PrEPVacc)

HIV Infections

Uganda
Washington State University
National Institute of Allergy and Infectious Diseases (NIAID); Washington University... and other collaborators

Recruiting

RVF and Other Emerging Infectious Diseases in East and Central Africa

Hemorrhagic Fevers, Viral | Rift Valley Fever

Congo, The Democratic Republic of the, Kenya, Tanzania, Uganda

Clinical Trials Sponsored by MRC/UVRI and LSHTM Uganda Research Unit

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cote d'Ivoire

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations