Clinical Trials Sponsored by National Comprehensive Cancer Network

Total 1322 results

Ohio State University Comprehensive Cancer Center
National Comprehensive Cancer Network

Recruiting

Electronic Symptom Monitoring Program for Triggered Palliative Referrals in Patients With Thoracic Cancer

Malignant Thoracic Neoplasm

United States
Ohio State University Comprehensive Cancer Center
National Comprehensive Cancer Network

Completed

Ph I Vorinostat in the Treatment of Advanced Staged Oropharyngeal Squamous Cell Carcinoma

Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IV Squamous Cell Carcinoma of the Oropharynx

United States
Ohio State University Comprehensive Cancer Center
National Comprehensive Cancer Network

Completed

Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Fox Chase Cancer Center
National Comprehensive Cancer Network

Completed

Treatment of Locally Advanced Non-Small Cell Lung Cancer (NSCLC) (NSCLC)

Locally Advanced Non-small Cell Lung Cancer

United States
M.D. Anderson Cancer Center
National Comprehensive Cancer Network

Recruiting

A Phase II Study of Futibatinib and Pembrolizumab in Metastatic Microsatellite Stable Endometrial Carcinoma

Metastatic Cancer | Endometrial Carcinoma | Endometrium Cancer

United States
M.D. Anderson Cancer Center
National Comprehensive Cancer Network

Completed

Hepatic Arterial Infusion (HAI) of Abraxane

Solid Tumors | Liver Cancer | Advanced Cancers

United States
M.D. Anderson Cancer Center
National Comprehensive Cancer Network

Completed

CPT-11/Cisplatin and Celecoxib With Radiation Therapy for Patients With Unresectable Non-Small Cell Lung Cancer (NSCLC)

Lung Cancer

United States
Fox Chase Cancer Center
National Comprehensive Cancer Network

Recruiting

Phase II Randomized Trial of Carboplatin+Pemetrexed+Bevacizumab+/- Atezolizumab in Stage IV NSCLC

Non-Small Cell Carcinoma of Lung, TNM Stage 4

United States
Northwestern University
National Comprehensive Cancer Network

Completed

Tivozanib in Recurrent, Platinum-Resistant Ovarian, Fallopian Tube or Primary Peritoneal Cancer (TIVO)

Recurrent Fallopian Tube Cancer | Recurrent Epithelial Ovarian Cancer | Recurrent Primary Peritoneal Cancer

United States
Stanford University
National Comprehensive Cancer Network

Completed

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Neoplasm Metastasis | Lung Cancer | Brain Cancer

United States
Stanford University
National Comprehensive Cancer Network

Completed

Phase I Bortezomib (VELCADE) in Combo With Pralatrexate in Relapsed/Refractory MM

Multiple Myeloma

United States
Stanford University
National Comprehensive Cancer Network

Completed

Evaluating Sunitinib Therapy in Renal Cell Carcinoma Using F-18 FDG PET/CT and DCE MRI

Kidney Neoplasms | Carcinoma, Renal Cell | Kidney (Renal Cell) Cancer

United States
Mayo Clinic
National Comprehensive Cancer Network

Completed

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Stage III Gallbladder Cancer AJCC v8 | Stage IIIA Gallbladder Cancer AJCC v8 | Stage IIIB Gallbladder Cancer AJCC v8 | Refractory Gallbladder Carcinoma | Stage IV Gallbladder Cancer AJCC v8 | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder... and other conditions

United States
Duke University
National Comprehensive Cancer Network

Withdrawn

Mirvetuximab Soravtansine (IMG853) in Folate Receptor Alpha-expressing TNBC (IMGN853)

Breast Cancer Triple Negative

United States
Duke University
National Comprehensive Cancer Network

Terminated

Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology In Men With Castration Resistant Metastatic Prostate Cancer

Prostate Cancer

United States
National Cancer Institute (NCI)
National Comprehensive Cancer Network

Completed

Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
M.D. Anderson Cancer Center
National Comprehensive Cancer Network; Cephalon

Completed

Bendamustine and Bevacizumab for Advanced Cancers

Advanced Cancer

United States
Bhavana Konda
National Comprehensive Cancer Network

Active, not recruiting

Dabrafenib With or Without Trametinib in Treating Patients With Recurrent Thyroid Cancer

Insular Thyroid Cancer | Recurrent Thyroid Cancer | Papillary Thyroid Cancer | Follicular Thyroid Cancer

United States
Ohio State University Comprehensive Cancer Center
Celgene Corporation; National Comprehensive Cancer Network

Completed

Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed By Surgery

Intraocular Melanoma

United States
Fox Chase Cancer Center
Pfizer; National Comprehensive Cancer Network

Completed

Improving the Approach to and Management of the Older Metastatic Breast Cancer Patient

Metastatic Breast Cancer

United States
Ohio State University Comprehensive Cancer Center
Novartis Pharmaceuticals; National Comprehensive Cancer Network

Completed

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
John Grecula
National Comprehensive Cancer Network

Completed

Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
Ohio State University Comprehensive Cancer Center
Genentech, Inc.; National Comprehensive Cancer Network

Completed

Bendamustine and Erlotinib in Treating Patients With Stage IIIB, Stage IIIC, or Stage IV Breast Cancer

Breast Cancer

United States
M.D. Anderson Cancer Center
GlaxoSmithKline; National Comprehensive Cancer Network

Completed

Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients

Solid Tumors | Advanced Cancers

United States
Manisha Shah
National Comprehensive Cancer Network

Completed

Dabrafenib and Pazopanib Hydrochloride in Treating Patients With Advanced Malignant Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Ohio State University Comprehensive Cancer Center
National Comprehensive Cancer Network; Spectrum Pharmaceuticals, Inc

Completed

Pralatrexate and Docetaxel in Treating Patients With Stage IV Esophageal or Gastroesophageal Cancer Who Have Failed Platinum-Based Therapy

Squamous Cell Carcinoma of the Esophagus | Adenocarcinomas of the Gastroesophageal Junction | Adenocarcinoma of the Esophagus | Recurrent Esophageal Cancer | Stage IV Esophageal Cancer

United States
Dana-Farber Cancer Institute
National Comprehensive Cancer Network

Completed

Safety Study of Afatinib and Postoperative Radiation Therapy to Treat Head and Neck Cancer

Squamous Cell Carcinoma of the Head and Neck

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Completed

Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Stage III Mantle Cell Lymphoma | Stage IV Mantle Cell Lymphoma | Stage I Mantle Cell Lymphoma | Stage II Contiguous Mantle Cell Lymphoma | Stage II Non-Contiguous Mantle Cell Lymphoma

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Active, not recruiting

Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage III Esophageal Adenocarcinoma AJCC v8 and other conditions

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Completed

Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer

Esophageal Cancer

United States
Dana-Farber Cancer Institute
National Comprehensive Cancer Network

Not yet recruiting

CV CARE: CardioVascular Care in PC Patients

Cardiovascular Diseases | Prostate Cancer

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Recruiting

Quality of Life Intervention to Inform Patient Decision-Making in Early-Stage Lung Cancer

Lung Non-Small Cell Carcinoma | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage I Lung Cancer AJCC v8 | Stage IA1 Lung Cancer AJCC v8 | Stage IA2 Lung Cancer AJCC v8 | Stage IA3 Lung Cancer AJCC v8 | Stage IB Lung Cancer AJCC v8

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Completed

Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Advanced Adult Hepatocellular Carcinoma | Localized Non-Resectable Adult Hepatocellular Carcinoma | Stage IIIA Hepatocellular Carcinoma | Stage IIIB Hepatocellular Carcinoma | Stage IIIC Hepatocellular Carcinoma | Stage IVA Hepatocellular Carcinoma | Stage IVB Hepatocellular Carcinoma | Stage III... and other conditions

United States
Northwestern University
GlaxoSmithKline; National Comprehensive Cancer Network

Active, not recruiting

Alemtuzumab-Ofatumumab in Previously Untreated Symptomatic Chronic Lymphocytic Leukemia

Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Stage III Chronic Lymphocytic Leukemia | Stage IV Chronic Lymphocytic Leukemia

United States, Sweden
Massachusetts General Hospital
National Comprehensive Cancer Network

Completed

Palliative And Oncology Care Model In Breast Cancer

Metastatic Breast Cancer

United States
Massachusetts General Hospital
National Comprehensive Cancer Network

Completed

Carfilzomib Plus Belinostat in Relapsed/Refractory NHL

Follicular Lymphoma | Mantle Cell Lymphoma | Non-Hodgkin Lymphoma | Peripheral T-cell Lymphoma | Diffuse Large B-cell Lymphoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Novartis; National Comprehensive Cancer Network

Completed

Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma

Cholangiocarcinoma | Soft-tissue Sarcoma | Solid Tumors | Thyroid Cancer

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Recruiting

Decitabine/Cedazuridine and Enzalutamide for the Treatment of Metastatic Castrate Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
Dana-Farber Cancer Institute
National Comprehensive Cancer Network

Active, not recruiting

A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer

Non-small Cell Lung Cancer

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Completed

Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

Carcinoid Tumor | Neuroendocrine Neoplasm | Metastatic Carcinoid Tumor

United States
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Active, not recruiting

TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Colon Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Comprehensive Cancer Network

Active, not recruiting

Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR Study

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
Massachusetts General Hospital
National Comprehensive Cancer Network

Active, not recruiting

Supportive Care Mobile Application for Patients With NSCLC

Quality of Life | Non Small Cell Lung Cancer | Coping Skills

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); National Comprehensive Cancer Network

Terminated

Afatinib and Necitumumab in Patients With EGFR Mutation Positive Advanced or Metastatic Non-small Cell Lung Cancer

Non-Small Cell Lung Carcinoma

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); National Comprehensive Cancer Network

Completed

Capecitabine, Vorinostat, and Radiation Therapy in Treating Patients With Nonmetastatic Pancreatic Cancer

Pancreatic Cancer | Periampullary Adenocarcinoma

United States
Memorial Sloan Kettering Cancer Center
Bayer; National Comprehensive Cancer Network

Active, not recruiting

Sorafenib Plus Doxorubicin in Patients With Advanced Hepatocellular Carcinoma With Disease Progression on Sorafenib

Hepatocellular Carcinoma

United States
Vanderbilt-Ingram Cancer Center
Boehringer Ingelheim; National Comprehensive Cancer Network

Withdrawn

Afatinib and Nivolumab as Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma | Recurrent Squamous Cell Carcinoma of the Head or Neck | Metastatic Squamous Cell Carcinoma of the Head or Neck
Memorial Sloan Kettering Cancer Center
Pfizer; National Comprehensive Cancer Network

Completed

Combination of Temsirolimus and Sorafenib in the Treatment of Radioactive Iodine Refractory Thyroid Cancer

Thyroid Cancer

United States
Memorial Sloan Kettering Cancer Center
Pfizer; National Comprehensive Cancer Network

Completed

Axitinib (AG-013736) in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma

United States
Johns Hopkins University
National Comprehensive Cancer Network

Recruiting

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry (DISSRM)

Kidney Neoplasm

United States

Clinical Trials Sponsored by National Comprehensive Cancer Network

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