Clinical Trials Sponsored by Positive Trial Group

Total 680 results

Trial Management Group Inc.
Hoffmann-La Roche

Completed

Effect of Oseltamivir on Cognitive Function in Subjects With Influenza (FOCUS)

Influenza

Canada
Clinical Trial Agency of HIV Study Group

Completed

VENICE Study Nevirapine Full Dose/Dose Escalation (VENICE)

HIV Infections

Spain
Trial Management Group Inc.
Hoffmann-La Roche

Terminated

Time to Oseltamivir Access When Prescribed by Pharmacists Versus Physicians (ACCESS) (Access)

Influenza

Canada
NCIC Clinical Trials Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

Thalidomide and Prednisone After Autologous Stem Cell Transplantation Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

Canada
Clinical Trial Agency of HIV Study Group

Completed

Once a Day (QD) - Twice a Day (BID) Clinical Trial: Didanosine, Lamivudine and Efavirenz Versus Zidovudine, Lamivudine and Efavirenz in the Starting Treatment of HIV

HIV Infections

Spain
ImmunoGen, Inc.
Gynecologic Oncology Group; European Network of Gynaecological Oncological...

Active, not recruiting

A Study of Mirvetuximab Soravtansine vs. Investigator's Choice of Chemotherapy in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression (MIRASOL)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Cancer

United States, Canada, Germany, China, France, Korea, Republic of, Belgium, United Kingdom, Serbia, Spain, Australia, Israel, Italy, Taiwan, Czechia, Bulgaria, Netherlands, Portugal, Poland, Russian Federation, Ukraine
Seagen Inc.
Gynecologic Oncology Group; European Network of Gynaecological Oncological... and other collaborators

Completed

A Trial of Tisotumab Vedotin in Cervical Cancer

Cervical Cancer

Belgium, Spain, United States, Denmark, Italy, Germany, Czechia, Sweden
Canadian Cancer Trials Group
Trans Tasman Radiation Oncology Group

Completed

Study Comparing Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy (CRT) for Spinal Metastases

Spinal Metastases

Canada, Australia
Canadian Cancer Trials Group
Amgen; Canadian Myeloma Research Group

Completed

High-Dose Weekly Carfilzomib Plus Cyclophosphamide and Dexamethasone in the Treatment of Relapsed Multiple Myeloma

Multiple Myeloma

Canada
Ontario Clinical Oncology Group (OCOG)
NCIC Clinical Trials Group

Completed

Shorter Radiation Schedule for the Treatment of Prostate Cancer

Prostate Cancer

Canada
Canadian Cancer Trials Group
Canadian Cancer Clinical Trials Network

Recruiting

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

Endometrial Cancer

Canada, Australia, Netherlands
NCIC Clinical Trials Group
National Cancer Institute (NCI); Southwest Oncology Group; North Central Cancer...

Completed

Bone Mineral Density in Postmenopausal Women With Primary Breast Cancer Who Are Receiving Treatment on Clinical Trial

Breast Cancer | Osteoporosis

Canada
Merck Sharp & Dohme LLC
Gynecologic Oncology Group; European Network for Gynaecological Oncological...

Active, not recruiting

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

Endometrial Neoplasms

United States, Argentina, Austria, Belgium, Canada, Chile, China, Colombia, Czechia, Denmark, Finland, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Mexico, Norway, Poland, Russian Federation, Spain, Sweden, Taiwan, T... and more
NCIC Clinical Trials Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Southwest... and other collaborators

Completed

Vinorelbine + Cisplatin or No Further Therapy in Non-small Cell Lung Cancer That Has Been Surgically Removed

Lung Cancer

United States, Canada
Canadian Cancer Trials Group
Janssen Inc.

Recruiting

Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma

Non-hodgkin Lymphoma

Canada
Canadian Cancer Trials Group
Apotex Inc.

Active, not recruiting

ASA in Prevention of Ovarian Cancer (STICs and STONEs)

Ovarian Cancer Prevention

Canada, Australia
Canadian Cancer Trials Group
Innate Pharma

Completed

A Dose-Ranging Study of IPH2201 in Patients With Gynecologic Malignancies

Gynecologic Cancer

Canada
Canadian Cancer Trials Group
Oncolytics Biotech

Completed

A Study of Reolysin For Patients With Advanced/Metastatic Breast Cancer

Metastatic Breast Cancer

Canada
Canadian Cancer Trials Group
Oncolytics Biotech

Completed

Reolysin Combined With Docetaxel and Prednisone or Docetaxel and Prednisone Alone in Metastatic Castration Resistant Prostate Cancer

Prostate Cancer

Canada
Canadian Cancer Trials Group
Repare Therapeutics

Recruiting

RP-6306 in Patients With Advanced Cancer

Advanced Cancer

Canada
Canadian Cancer Trials Group
Oncolytics Biotech

Completed

Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Metastatic Colorectal Cancer

Colorectal Cancer

Canada
Canadian Cancer Trials Group
Oncolytics Biotech

Completed

Reolysin in Previously Treated Advanced/Metastatic, Non Small Cell Lung Cancer Receiving Standard Salvage Therapy

Non Small Cell Lung Cancer

Canada
Rectal Cancer Trial on Defunctioning Stoma Study...

Unknown

Early Reversal of Defunctioning Stoma Trial (ELSOR)

Rectal Cancer

Sweden
Rectal Cancer Trial on Defunctioning Stoma Study...

Completed

Rectal Cancer Trial On Defunctioning Stoma (RECTODES)

Rectal Cancer

Sweden
Canadian Cancer Trials Group
NRG Oncology

Recruiting

Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment (ASCENDE-SBRT)

Prostate Cancer

Canada
Canadian Cancer Trials Group
Jazz Pharmaceuticals

Recruiting

Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma

Gastroesophageal Adenocarcinoma

Canada
Trans Tasman Radiation Oncology Group
European Organisation for Research and Treatment of Cancer - EORTC; NCIC Clinical... and other collaborators

Active, not recruiting

Radiation Doses and Fractionation Schedules in Non-low Risk Ductal Carcinoma In Situ (DCIS) of the Breast (DCIS)

Carcinoma, Ductal, Breast

United Kingdom, Netherlands, Ireland, Switzerland, Australia, Singapore, New Zealand, Belgium, Canada, Italy, France
Canadian Cancer Trials Group
Australia New Zealand Gynaecological Oncology Group

Not yet recruiting

STRatIfication of Vulvar SCC by HPV and p53 Status to Guide Excision (STRIVE)

Vulvar Squamous Cell Carcinoma
Trans Tasman Radiation Oncology Group
Australasian Lung Cancer Trials Group

Completed

A Randomized Phase II Study of Stereotactic Ablative Body Radiotherapy for Metastases to the Lung (TROG 13.01 SAFRON II) (SAFRON II)

Cancer | Metastases to the Lung

Australia
Canadian Cancer Trials Group
Melanoma and Skin Cancer Trials Limited

Recruiting

Duration of Anti-PD-1 Therapy in Metastatic Melanoma (STOP-GAP)

Unresectable/Metastatic Melanoma

Canada, Australia
NCIC Clinical Trials Group
National Cancer Institute (NCI); Medical Research Council; Eastern Cooperative... and other collaborators

Completed

Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

Canada
Merck Sharp & Dohme LLC
Gynecologic Oncology Group; European Network of Gynaecological Oncological...

Active, not recruiting

Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

Poland, Korea, Republic of, United States, Australia, Belgium, Brazil, Canada, Chile, Colombia, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Russian Federation, South Africa, Spain, Taiwan, Turkey, Ukraine
Canadian Cancer Trials Group
Queen's University, Belfast; Survivorship Research Group

Active, not recruiting

Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer (CHALLENGE)

Depression | Fatigue | Colorectal Cancer | Sleep Disorders | Cognitive/Functional Effects | Anxiety Disorder | Psychosocial Effects of Cancer and Its Treatment | Excercise

Canada, United States, Australia, France, Korea, Republic of, United Kingdom
Canadian Cancer Trials Group
Celgene; Australian and New Zealand Urogenital and Prostate Cancer Trials Group

Completed

Nab-Paclitaxel to Paclitaxel in Advanced Urothelial Cancer Progressing on or After Platinum Containing Regimen.

Urothelial Cancer

Canada, Australia
University of Sydney
Canadian Cancer Trials Group; Australian and New Zealand Urogenital and Prostate... and other collaborators

Active, not recruiting

Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer (ENZAMET)

Prostatic Neoplasms

New Zealand, Canada, United States, Australia, United Kingdom, Ireland
University College, London
Canadian Cancer Trials Group

Completed

RADICALS - Radiotherapy and Androgen Deprivation In Combination After Local Surgery

Sexual Dysfunction | Prostate Cancer | Gastrointestinal Complications | Urinary Complications

United Kingdom, Canada
Novartis Pharmaceuticals
NCIC Clinical Trials Group

Completed

Chemotherapy and Lapatinib or Trastuzumab in Treating Women With HER2/Neu-Positive Metastatic Breast Cancer

Breast Cancer

United States, Belgium, Canada, United Kingdom, Argentina, Australia, France, Germany, Israel, Italy, Japan, Netherlands, Poland, Russian Federation, Spain, Taiwan, Thailand, India, Korea, Republic of, Mexico, Ukraine
The George Institute
ANZICS Clinical Trials Group

Completed

Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF).

Acute Renal Failure

Australia
Gynecologic Oncology Trial & Investigation Consortium
Japanese Gynecologic Oncology Group

Completed

Intraperitoneal Therapy For Ovarian Cancer With Carboplatin Trial (iPocc)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

Japan, United States, Hong Kong, Korea, Republic of, New Zealand, Singapore
Canadian Cancer Trials Group
Hoffmann-La Roche

Recruiting

Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive (ER+) Breast Cancer Following Progression on First Line CDK 4/6 Inhibitor and Aromatase Inhibitor (FINER)

Breast Cancer

Canada, Australia, New Zealand
Anders Perner

Completed

Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care (CLASSIC)

Sepsis | Septic Shock

Denmark, Finland
Novartis Pharmaceuticals
Canadian Cancer Trials Group

Completed

A Study of Letrozole in the Treatment of Endometrial Cancer

Recurrent and Metastatic Endometrial Cancer

Germany
University of Toronto
Canadian Cancer Trials Group

Completed

Effectiveness of an Individualized Symptom Education Program (ISEP)

Cervical Cancer | Vulvar Cancer | Vaginal Cancer | Uterine Cancer

Canada
Southwest Oncology Group
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

S0226 Anastrozole With or Without Fulvestrant as First-Line Therapy in Postmenopausal Women With Metastatic Breast Cancer

Breast Cancer

Canada, United States
National Cancer Institute (NCI)
Gynecologic Oncology Group; NCIC Clinical Trials Group

Terminated

Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer

Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Stage IB Cervical Cancer | Stage IIA Cervical Cancer | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage IVA Cervical Cancer | Cervical Adenosquamous Cell Carcinoma

United States, Canada
Centre Hospitalier Universitaire de Besancon
European Network of Gynaecological Oncological Trial Groups (ENGOT); ARCAGY...

Recruiting

International Validation Study of Sentinel Node Biopsy in Early Cervical Cancer (SENTICOLIII)

Cervical Cancer

Spain, France, Germany, Czechia, Switzerland, China, Japan, Brazil, Italy, Canada, India, Norway, Slovakia
PrecisionBiotics Group Ltd.
Atlantia Food Clinical Trials

Completed

The Effects of Bifidobacterium Longum 1714® in a Population With Low Mood

Depressive Symptoms | Low Mood

Ireland
Tesaro, Inc.
Gynecologic Oncology Group; European Network of Gynaecological Oncological... and other collaborators

Active, not recruiting

A Study of Niraparib (GSK3985771) Maintenance Treatment in Participants With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

Ovarian Neoplasms

United States, Spain, Finland, Czechia, Italy, Denmark, Germany, Belgium, Israel, Canada, Russian Federation, Sweden, United Kingdom, Poland, Ireland, Ukraine, France, Norway, Switzerland, Hungary
ETOP IBCSG Partners Foundation
Alliance for Clinical Trials in Oncology; Canadian Cancer Trials Group; Breast...

Active, not recruiting

Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer (POSITIVE)

Early Breast Cancer

Korea, Republic of, United States, France, Canada, Spain, Lebanon, Belgium, Switzerland, Israel, Ireland, Japan, Italy, Denmark, Austria, Australia, Greece, Hungary, Netherlands, Norway, Portugal, Serbia, Slovenia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Active, not recruiting

Surgery With or Without Docetaxel and Leuprolide or Goserelin in Treating Patients With High-Risk Localized Prostate Cancer

Prostate Cancer

United States, Canada

Clinical Trials Sponsored by Positive Trial Group

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