Clinical Trials Sponsored by Royal Marsden NHS Foundation Trust

Total 3525 results

Royal Marsden NHS Foundation Trust
Imperial College London

Not yet recruiting

IMaC - Immune Pathways in Oesophagogastric Cancer (IMaC)

Oesophagogastric Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
University of Leeds

Recruiting

EVEREST-HN 1: EVolution of a patiEnt-REported Symptom-based Risk Stratification sySTem

Head and Neck Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Ventana Medical Systems

Recruiting

Value of Analysing Under-utilised Leftover Tissue (VauLT) (VauLT)

Oncology

United Kingdom
Royal Marsden NHS Foundation Trust
Francis Crick Institute

Recruiting

TRACERx Renal CAPTURE Sub-study (TRACERxRenal)

Renal Cell Carcinoma | Cancer | Healthy Volunteers

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London

Active, not recruiting

Changes to Function and Quality of Life and Patient Experience for Patients Undergoing Treatments for Recurrent Oropharyngeal Cancer (FUNQOLR)

Recurrent Oropharynx Carcinoma

United Kingdom
Royal Marsden NHS Foundation Trust
Boehringer Ingelheim; Celgene

Withdrawn

Combination Nab-paclitaxel (N-P) and Nintedanib or N-P and Placebo in Relapsed NSCLC Adenocarcinoma (N3)

Adenocarcinoma of Lung | NSCLC, Recurrent
Royal Marsden NHS Foundation Trust
Cancer Research UK

Unknown

CHOP vs GEM-P in 1st Line Treatment of T-cell Lymphoma, Multicentre Phase II Study (CHEMO-T)

Angioimmunoblastic T-cell Lymphoma | Enteropathy-Associated T-Cell Lymphoma | Anaplastic Large Cell Lymphoma, ALK-Negative | Peripheral T-cell Lymphoma NOS | Hepatosplenic Gamma/ Delta T-cell Lymphoma

United Kingdom
Royal Marsden NHS Foundation Trust
University of Surrey

Completed

A Survivorship Care Plan for Gynaecological Cancer Patients

Sarcoma | Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London

Completed

Chemotherapy Induced Painful Peripheral Neuropathy Ethosuximide (The CIN-E Study) (CINE-E)

Cancer | Peripheral Neuropathy

United Kingdom
Royal Marsden NHS Foundation Trust
Roche Pharma AG

Completed

Capecitabine and Oxaliplatin Plus Bevacizumab as Neoadjuvant Treatment for Untreated Unresectable Liver-only Metastases From Colorectal Cancer

Metastatic Colorectal Cancer

United Kingdom
University of Surrey
Royal Marsden NHS Foundation Trust

Completed

Body Image Issues in Boys Being Treated at the Royal Marsden

Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London; St. George's NHS Foundation Trust

Unknown

Lab-on-a-chip Detection of Cervical Cancer Tumour Markers (MODULAR)

Cervical Cancer
Royal Marsden NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust; University Hospital Plymouth...

Unknown

Tissue Collection for Biomarkers Determining Resistance to Ibrutinib (CLARITY)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukaemia

United Kingdom
Royal Marsden NHS Foundation Trust
Pfizer; Breast Cancer Now

Recruiting

PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer (PAveMenT)

Metastatic Breast Cancer | Triple Negative Breast Cancer | HER2-positive Breast Cancer | Locally Advanced Breast Cancer | Recurrent Breast Cancer | ER+ Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC

Terminated

Pembrolizumab and Hypofractionated Stereotactic Radiotherapy in Patients With Malignant Pleural Mesothelioma (MESO-PRIME)

Advanced Malignant Pleural Mesothelioma

United Kingdom
Royal Marsden NHS Foundation Trust
Merck KGaA, Darmstadt, Germany

Active, not recruiting

Study Title: Peri-operative Immuno-Chemotherapy in Operable Oesophageal and Gastric Cancer (ICONIC)

Gastric Adenocarcinoma | Oesophageal Adenocarcinoma

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological Cancer

Sarcoma | Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Low-Fiber Diet or High-Fiber Diet in Preventing Bowel Side Effects in Patients Undergoing Radiation Therapy for Gynecological Cancer, Bladder Cancer, Colorectal Cancer, or Anal Cancer

Sarcoma | Cervical Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Bladder Cancer | Anal Cancer | Radiation Toxicity | Gastrointestinal Complications

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Vitamin E and Pentoxifylline in Treating Women With Lymphedema After Radiation Therapy for Breast Cancer

Breast Cancer | Lymphedema

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Sargramostim to Prevent Mucositis in Patients Receiving Radiation Therapy for Laryngeal Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Intensity-Modulated Radiation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United Kingdom
Royal Marsden NHS Foundation Trust
Merck KGaA, Darmstadt, Germany

Active, not recruiting

Phase I Study Compound 451238 and Radiotherapy in Soft-tissue Sarcoma

Soft-tissue Sarcoma

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma (GEMMK)

Sarcoma

United Kingdom
The Netherlands Cancer Institute
Royal Marsden NHS Foundation Trust

Terminated

Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients (PASART-2)

Sarcoma | Soft Tissue Sarcomas

United Kingdom, Netherlands
Royal Marsden NHS Foundation Trust

Completed

Reflexology or Aromatherapy Massage in Relieving Symptoms in Patients With Cancer

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Psychosocial Effects of Cancer and Its Treatment

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Sentinel Lymph Node Biopsy to Assess Axillary Lymph Nodes in Women With Stage I or Stage II Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast Cancer

Breast Cancer | Radiation Fibrosis

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Comparison of Three Combination Chemotherapy Regimens in Treating Women With Stage I or Stage II Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Duct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Follow-up Evaluation Using CT Scans in Patients Who Have Been Treated For Metastatic Testicular Cancer

Testicular Germ Cell Tumor

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer

Sarcoma | Cervical Cancer | Testicular Germ Cell Tumor | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Endometrial Cancer | Radiation Toxicity | Vaginal Cancer | Gastrointestinal Complications | Long-term Effects Secondary to Cancer Therapy in Adults

United Kingdom
Royal Marsden NHS Foundation Trust
Pfizer; Hoffmann-La Roche

Recruiting

Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Suppression (FAIM)

Advanced Breast Cancer | Metastatic Breast Cancer | ER+ Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Pfizer; Breast Cancer Now

Active, not recruiting

Crizotinib in Lobular Breast, Diffuse Gastric and Triple Negative Lobular Breast Cancer or CDH1-mutated Solid Tumours (ROLo)

Gastric Cancer | Triple Negative Breast Cancer | Lobular Breast Carcinoma | CDH1 Gene Mutation

United Kingdom
Vitaccess Ltd
Royal Marsden NHS Foundation Trust; Melanoma UK

Completed

The Impact of Melanoma and Drug Treatment in the Real World

Melanoma

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC

Terminated

PembRolIzuMab and Stereotactic Body Radiotherapy In Metastatic Non-small-cell lunG Cancer Patients (PRIMING)

Metastatic Non-small-cell lunG Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Malaysia Palm Oil Board

Completed

PPALM-Palm Oil and Pentoxifylline Against Late Morbidity (PPALM)

Long-term Adverse Effects of Radiotherapy for Pelvic Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
City, University of London

Unknown

Radiation Exposure Awareness From Patients Undergoing Nuclear Medicine Diagnostic Scans (REA)

FDG PET/CT | Skeletal Scintigraphy

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC

Withdrawn

A Study of Anti-PD-1 (Pembrolizumab) Therapy in Metastatic Melanoma (ADAPTeM) (ADAPTeM)

Advanced Melanoma
Royal Marsden NHS Foundation Trust
Merck Serono International SA

Terminated

A Clinical Study of UFT/Leucovorin, Radiotherapy With or Without Cetuximab Following Induction Gemcitabine Plus Capecitabine in Patients With Locally Advanced Pancreatic Cancer (PERU) (PERU)

Pancreatic Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Nipple Aspiration, Ductal Lavage, and Duct Endoscopy in Screening Women at Moderate-to-High Risk of Developing Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Diagnosis and Treatment Planning in Patients Suspected of Having Lung Cancer

Lung Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Enhanced Ultrasound in Determining Extent of Disease in Women With Primary Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer

Breast Cancer | Lymphedema | Perioperative/Postoperative Complications

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Multifunctional Magnetic Resonance Imaging in Predicting Breast Lesions in Women Undergoing Mastectomy for Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Nipple Aspiration, Ductal Lavage, and Duct Endoscopy For Diagnostic Assessment in Women Undergoing Surgery for Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Care of Cancer Patients With Bowel Injury Caused by Radiation Therapy to the Pelvis

Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Radiation Therapy Planning Techniques in Reducing Damage to Normal Tissue in Women Undergoing Breast-Conserving Surgery for Ductal Carcinoma of the Breast

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Oracle Cancer Trust; Biomedical Research Centre

Recruiting

Exploratory Study of Clonal Evolution in Cancer for Patients Undergoing Transoral Robotic Surgery for Radiation Exposed Residual/reCurrent Tumours of the Upper Aerodigestive Tract (RECUT Plus)

Head and Neck Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
Massachusetts General Hospital; Natera, Inc.

Recruiting

Safe De-escalation of Chemotherapy for Stage 1 Breast Cancer (Safe-De)

Breast Cancer

United Kingdom

Clinical Trials Sponsored by Royal Marsden NHS Foundation Trust

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