Clinical Trials Sponsored by Royal Tropical Institute

Total 965 results

Cairo University
Theodor Bilharz Research Institute; National Hepatology & Tropical Medicine...

Unknown

Kaffes Stent in the Management of Post-surgical Biliary Strictures

Cholangitis | Biliary Stricture | Bile Duct Injury | Bile Duct Stricture | Benign Biliary Stricture

Egypt
Nasser Aghdami MD., PhD

Completed

Intracoronary Transplantation of Bone Marrow Derived Mononuclear Cells in Pediatric Cardiomyopathy

Cardiomyopathy

Iran, Islamic Republic of
Tropical Medicine Research Institute
London School of Hygiene and Tropical Medicine; World Health Organization; International...

Completed

The Impact of Artemether-Lumefantrine on Genes Associated With Antimalarial Resistance

Falciparum Malaria | Antimalarials

Sudan
Swiss Tropical & Public Health Institute
National Institute of Public Health, Vientiane, Laos

Not yet recruiting

Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis

Strongyloidiasis | Strongyloides Stercoralis Infection
University Hospital, Basel, Switzerland
Swiss Tropical & Public Health Institute; Ifakara Health Institute

Completed

Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa (RenalOne)

HIV Infections | Hypertension | Diabetes Mellitus | Chronic Kidney Diseases | Tuberculosis | Schistosomiasis

Switzerland
Jennifer Keiser
Vector Borne & Neglected Tropical Disease Control Division, Ministry of Health...

Completed

Efficacy of Ivermectin-albendazole vs Albendazole Alone in School-aged Children Infected With Trichuris Trichiura (FACEITeffic)

Trichuriasis

Uganda
Swiss Tropical & Public Health Institute
University Hospital, Basel, Switzerland; Ifakara Health Institute

Recruiting

Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa (RenalTWO)

Cardiovascular Diseases | HIV Infections | Infections | Obesity | Chronic Kidney Diseases | Type 2 Diabetes Mellitus | Anemia | Dyslipidemias | Albuminuria | Arterial Hypertension | Underweight

Tanzania
Swiss Tropical & Public Health Institute
Drugs for Neglected Diseases; Ifakara Health Institute

Completed

PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets (HELP-OFZ)

Filariasis

Tanzania
Swiss Tropical & Public Health Institute
Rehab Basel; University of Basel

Recruiting

Long-term Effects of AAT in Patients With ABI

Acquired Brain Injury

Switzerland
University of California, Davis
Lao Tropical and Public Health Institute

Completed

Further Development and Assessment of Tools to Measure Risk Factors for and Treatment of Thiamine Deficiency Disorders

Thiamine Deficiency

Lao People's Democratic Republic
London School of Hygiene and Tropical Medicine
Wellcome Sanger Institute

Completed

Global Syphilis Sequencing

Syphilis

United Kingdom
Swiss Tropical & Public Health Institute
Rehab Basel; University of Basel

Completed

Neurovascular Reactions to AAT in Patients With DOC (AAT NIRS)

Brain Injuries | Consciousness Disorder

Switzerland
Christoph Hatz
University of Zurich

Completed

The Effect of Hand Hygiene on Colonization Rates With Multidrug Resistant Enteric Pathogens in Travellers

Drug Resistance, Multiple | Travel Medicine

Switzerland
Institute of Tropical Medicine, Belgium
KU Leuven; Université de Kisangani

Completed

Reservoir of Invasive Salmonellosis in Children, DRC

Salmonella Infections | Infection of Bloodstream

Congo, The Democratic Republic of the
Swiss Tropical & Public Health Institute
Pevion Biotech Ltd; Mymetics Corporation

Completed

Phase Ib Trial of Two Virosome Formulated Malaria Vaccine Components (PEV 301, PEV 302) in Tanzania (PMAL03)

Falciparum Malaria

Tanzania
Murdoch Childrens Research Institute
Royal Children's Hospital; Monash Health

Recruiting

Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children (MIST+)

Snoring | Tonsillar Hypertrophy | Sleep Disorder; Breathing-Related | Obstructive Sleep Apnea of Child | Sleep Disorders in Children | Adenoidal Disorder

Australia
Royal Marsden NHS Foundation Trust

Completed

Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological Cancer

Sarcoma | Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Low-Fiber Diet or High-Fiber Diet in Preventing Bowel Side Effects in Patients Undergoing Radiation Therapy for Gynecological Cancer, Bladder Cancer, Colorectal Cancer, or Anal Cancer

Sarcoma | Cervical Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Bladder Cancer | Anal Cancer | Radiation Toxicity | Gastrointestinal Complications

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Vitamin E and Pentoxifylline in Treating Women With Lymphedema After Radiation Therapy for Breast Cancer

Breast Cancer | Lymphedema

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Sargramostim to Prevent Mucositis in Patients Receiving Radiation Therapy for Laryngeal Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Intensity-Modulated Radiation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United Kingdom
Region Stockholm
KTH Royal Institute of Technology; Getinge Group

Not yet recruiting

Artificial Intelligence - to Predict and Prevent Hypotension During Surgery

Monitoring, Intraoperative
Royal Marsden NHS Foundation Trust

Completed

Nipple Aspiration, Ductal Lavage, and Duct Endoscopy in Screening Women at Moderate-to-High Risk of Developing Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Diagnosis and Treatment Planning in Patients Suspected of Having Lung Cancer

Lung Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Enhanced Ultrasound in Determining Extent of Disease in Women With Primary Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer

Breast Cancer | Lymphedema | Perioperative/Postoperative Complications

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Multifunctional Magnetic Resonance Imaging in Predicting Breast Lesions in Women Undergoing Mastectomy for Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Nipple Aspiration, Ductal Lavage, and Duct Endoscopy For Diagnostic Assessment in Women Undergoing Surgery for Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Care of Cancer Patients With Bowel Injury Caused by Radiation Therapy to the Pelvis

Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Radiation Therapy Planning Techniques in Reducing Damage to Normal Tissue in Women Undergoing Breast-Conserving Surgery for Ductal Carcinoma of the Breast

Breast Cancer

United Kingdom
Rwanda Biomedical Centre
Institute of Tropical Medicine; World Health Organization

Recruiting

Preventing Acquired Resistance: Strengthen TB Treatment by Adding Amikacin in the First Treatment Week of Multidrug-resistant Tuberculosis (Stake)

Tuberculosis, Multidrug-Resistant

Rwanda
Fundação de Medicina Tropical Dr. Heitor Vieira...
Butantan Institute

Active, not recruiting

Effectiveness of the Adsorbed Vaccine COVID-19 (Coronavac) Among Education and Public Safety Workers With Risk Factors for Severity (COVACMANAUS)

Covid19

Brazil
Wageningen University
University of Ibadan; International Institute for Tropical Agriculture

Completed

The Efficacy of Pro-vitamin A Biofortified Cassava on Vitamin A Status in Nigerian Preschool Children (CASSAVITA II)

Vitamin A Deficiency

Nigeria
Institute of Tropical Medicine, Belgium
University of Liverpool; Rinda Ubuzima

Completed

Safety and Acceptability of Vaginal Rings That Protect Women From Unintended Pregnancy (Ring-Plus)

Contraception

Rwanda
Swiss Tropical & Public Health Institute
Institute of Tropical Medicine, Belgium; B.P. Koirala Institute of Health Sciences and other collaborators

Completed

Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders (NIDIAGDigest)

Shigellosis | Schistosomiasis | Strongyloidiasis | Dientamoebiasis | Giardiasis | Amoebiasis | Soil-transmitted Helminthiasis | Intestinal Salmonellosis | Campylobacteriosis | Aeromonas Spp. Infections | Cryptosporidium Spp. Infections

Côte D'Ivoire, Indonesia, Mali, Nepal
University of California, Davis
Lao Tropical and Public Health Institute

Completed

Thiamine Responsive Disorders (TRD) Among Infants in Lao PDR

Thiamine Deficiency

Lao People's Democratic Republic
The Netherlands Cancer Institute
Royal Marsden NHS Foundation Trust

Terminated

Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients (PASART-2)

Sarcoma | Soft Tissue Sarcomas

United Kingdom, Netherlands
Royal Marsden NHS Foundation Trust

Completed

Reflexology or Aromatherapy Massage in Relieving Symptoms in Patients With Cancer

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Psychosocial Effects of Cancer and Its Treatment

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Sentinel Lymph Node Biopsy to Assess Axillary Lymph Nodes in Women With Stage I or Stage II Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast Cancer

Breast Cancer | Radiation Fibrosis

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Comparison of Three Combination Chemotherapy Regimens in Treating Women With Stage I or Stage II Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Duct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast Cancer

Breast Cancer

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Follow-up Evaluation Using CT Scans in Patients Who Have Been Treated For Metastatic Testicular Cancer

Testicular Germ Cell Tumor

United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer

Sarcoma | Cervical Cancer | Testicular Germ Cell Tumor | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Endometrial Cancer | Radiation Toxicity | Vaginal Cancer | Gastrointestinal Complications | Long-term Effects Secondary to Cancer Therapy in Adults

United Kingdom
Murdoch Childrens Research Institute
Sydney Children's Hospitals Network; Royal Children's Hospital; Monash Health; Royal...

Not yet recruiting

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2) (VANCAPP)

Infections | Sepsis | Bacteremia

Australia
Liverpool School of Tropical Medicine
Kenya Medical Research Institute; Institute of Primate Research

Enrolling by invitation

Mapping Snakebite Risk in Kenya and Eswatini

Epidemiology | Snakebite

Kenya
National Institute of Malariology, Parasitology...
Institute of Tropical Medicine, Belgium

Unknown

P. Falciparum Resistance to Artemisinin in Vietnam

Drug Resistant Malaria Due to Plasmodium Falciparum

Vietnam
London School of Hygiene and Tropical Medicine
Statens Serum Institut

Completed

Evaluation of Local Mechanisms for Staff Motivation to Reduce Hospital Mortality

Malaria | Hospital Mortality

Guinea-Bissau
Institute of Tropical Medicine, Belgium
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique...

Active, not recruiting

Febrile Illness in Kinshasa and Kimpese (FIKI²)

Febrile Illness

Congo, The Democratic Republic of the

Clinical Trials Sponsored by Royal Tropical Institute

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