Clinical Trials Sponsored by Sara Seifert

Total 1280 results

Universiti Teknologi Mara

Completed

Behavior Intervention for Weight Loss for Type 2 Diabetes Mellitus Adults With Obesity Problem (BMI of ≥23kg/m2) (BMI)

Obesity | Diabetes Mellitus, Type 2 | Behavior

Malaysia
Cara Therapeutics, Inc.

Completed

CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis Patients

Hemodialysis

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Czechia, Hungary, Poland
Cara Therapeutics, Inc.

Completed

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Puerto Rico
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Healthy | Hemodialysis

United States
Sana Klinikum Offenbach

Completed

Addiction Remission and Addiction Transfer After Bariatric Surgery

Obesity

Germany
A.T. Resolve SARL

Completed

Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery

Pain | Inflammation | Cataract

United States
Sana Klinikum Offenbach

Completed

Obesity and Metabolic Surgery in Patients With Type I Diabetes

Type I Diabetes
Sera Prognostics, Inc.

Completed

Proteomic Assessment of Preterm Birth (PAPR)

Preterm Birth

United States
Nara Medical University

Completed

New Angiotensin II Receptor Blocker Azilsartan Study for Stronger Blood Pressure Lowering (NARA)

Hypertension

Japan
Cara Therapeutics, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Pruritus | Notalgia Paresthetica

United States, Poland, Spain, Canada, Germany
Cara Therapeutics, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Medos International SARL

Recruiting

A Study of Implantation of CRENEOUS ENTERPRISE 2 Intracranial Stent in Participants With Severe Symptomatic Intracranial Atherosclerotic Stenosis

Intracranial Atherosclerosis

China
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Universiti Teknologi Mara

Completed

HIV Education Kit for Adolescents (Pencegahan HIV di Kalangan Remaja), PREM-Kit (PREM-Kit)

Human Immunodeficiency Virus

Malaysia
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Universiti Teknologi Mara

Active, not recruiting

Silver Diamine Fluoride: A Randomized Controlled Trial on Its Effectiveness As A Caries Arresting Agent

Quality of Life | Dental Caries

Malaysia
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Sana Klinikum Offenbach

Completed

Impedance Spectroscopy in Esophageal Cancer

Cancer of Esophagus

Germany
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KARE)

Pruritus | Atopic Dermatitis

United States, Canada
Universiti Teknologi Mara

Unknown

Low-Volume Interval Training and Resistance Exercise in Individual With Stroke

Stroke

Malaysia
Cara Therapeutics, Inc.

Completed

A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
Sana Klinikum Offenbach

Completed

MGB/OAGB Versus RYGB After Failed Sleeve

Obesity

Germany
Universiti Teknologi Mara

Unknown

Physical Fitness, Exercise Self-efficacy, Physical Activity Level in People With Spinal Cord Injury (SCI)

Spinal Cord Injuries | Physical Disability
Cara Therapeutics, Inc.

Completed

A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee

Osteoarthritis

United States
Cara Therapeutics, Inc.

Completed

Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus

Pruritus | Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery

Acute Pain

United States
Cara Therapeutics, Inc.

Completed

A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery

Acute Pain

United States
Nara Medical University

Completed

Angiotensin II Receptor Blockers (ARB) and ACE Inhibitors (ACEI) on Silent Brain Infarction and Cognitive Decline

Hypertension | Brain Infarction

Japan
PT. Sari Husada

Unknown

Efficacy Study of Multiple Micro Nutrients Supplementation (Babytop)

Anemia, Iron-deficiency

Indonesia
Nara Medical University

Terminated

The Effects of Carperitide on Short and Long-term Prognosis in Patients With Both Cardiac and Renal Failure

Heart Failure | Renal Failure

Japan
Sarah Lawrence College

Unknown

Schizophrenia and Genetic Counseling

Schizophrenia
Nara Medical University

Unknown

Hemofiltration for Contrast-Induced Nephropathy

Chronic Kidney Disease | Cardiac Catheterization

Japan
sara mostafa amin eladawy

Completed

Clinical and Economic Outcome of Simvastatin in Critically Ill Septic Patient

Critical Illness

Egypt
Cara Medical Ltd

Recruiting

Intra-procedural ECG Changes During TAVR

Transcatheter Aortic Valve Replacement | Conduction Disturbance

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)

Pruritus | Notalgia Paresthetica

United States, Canada
Sana Klinikum Offenbach

Terminated

One-anastomosis Gastric Bypass/Mini-Gastric Bypass Versus Roux-en Y Gastric Bypass (MGBvsRYGB)

Obesity

Germany
Cara Therapeutics, Inc.

Approved for marketing

Intermediate-Size Patient Population Expanded Access Program for Intravenous Difelikefalin

Uremic Pruritus
Cara Therapeutics, Inc.

Completed

CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-2)

Uremic Pruritus

United States, Canada, Czechia, Australia, Germany, Hungary, Korea, Republic of, New Zealand, Poland, Taiwan, United Kingdom
Sera Prognostics, Inc.

Completed

A Multicenter Assessment of a Spontaneous Preterm Birth Risk Predictor (TREETOP)

Preterm Birth

United States
Sana Klinikum Offenbach

Completed

Preoperative Condition in Giant Obese Patients

Morbid Obesity | Bariatric Surgery Candidate

Germany
Cara Therapeutics, Inc.

Completed

Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery

Post Abdominal Surgery Pain

United States
Sana Klinikum Offenbach

Completed

Chronic Inflammation After Obesity Surgery

Obesity
Sana Klinikum Offenbach

Completed

Long Term Results After Sleeve Gastrectomy

Obesity
Sana Klinikum Offenbach

Completed

Edmonton Obesity Staging System: Post-operative Outcome and 30-day Mortality

Postoperative Complications | Other Complications of Other Bariatric Procedure

Germany
Cara Therapeutics, Inc.

Completed

Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery

Postoperative Pain

United States
Para Federal University

Completed

The Use of Low Level Laser Therapy for Wound Healing in Leprosy Patients

Leprosy

Brazil

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