Clinical Trials Sponsored by Somaxon Pharmaceuticals

Total 19528 results

Alexion Pharmaceuticals

Completed

Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)

Hypophosphatasia

United States, United Arab Emirates, United Kingdom
OncBioMune Pharmaceuticals

Unknown

Study of Proscavax Vaccine in Patients With Localized Prostate Cancer vs Active Surveillance

Prostate Cancer

United States
Endo Pharmaceuticals

Completed

Open-Label Safety and Tolerability Study of Oxymorphone for Acute Postoperative Pain in Pediatric Subjects.

Postoperative Pain

United States
ORIC Pharmaceuticals

Completed

Single and Multiple Dose Study of ORIC-101 in Adult Healthy Subjects

Healthy Volunteers

United Kingdom
Alexion Pharmaceuticals

Completed

Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency

Wolman Disease | Lysosomal Acid Lipase Deficiency

United Kingdom, France, United States, Egypt, Ireland
Alnylam Pharmaceuticals

Terminated

INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP

Acute Hepatic Porphyria | Acute Intermittent Porphyria (AIP) | Hereditary Coproporphyria (HCP) | Variegate Porphyria (VP) | ALA Dehydratase Deficient Porphyria (ADP) | Hepatic Porphyrias | Porphyria Acute

United States
Quark Pharmaceuticals

Completed

A Study to Evaluate Efficacy and Safety of QPI-1002 for Prevention of Acute Kidney Injury Following Cardiac Surgery

Acute Kidney Injury

United States, Canada, Germany
Alnylam Pharmaceuticals

Terminated

A Study of an Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

Antitrypsin Deficiency Liver Disease

United Kingdom
Titan Pharmaceuticals

Completed

Re-Treatment Study of Probuphine in Opioid Addiction

Opioid Dependency

United States
Titan Pharmaceuticals

Completed

Safety and Efficacy of Probuphine in the Treatment of Opioid Dependence

Opioid Dependence

United States
Titan Pharmaceuticals

Completed

Extension to Safety and Efficacy of Probuphine in the Treatment of Opioid Dependence (PRO-807)

Opioid Dependence

United States
Ferring Pharmaceuticals

Terminated

Study to Assess Long-term Effectiveness of Zomacton® and Treatment Adherence in Patients With Growth Hormone Deficiency or Ullrich-Turner Syndrome (RAZANT)

Growth Disorders

Germany
Ferring Pharmaceuticals

Completed

Effectiveness and Safety of Firmagon® in Androgen Ablative Therapy of Advanced Hormone-dependent Prostate Carcinoma in Argentina (FAST AR)

Advanced Hormone Dependent Prostate Cancer

Argentina
Regeneron Pharmaceuticals

Completed

Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN3918 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Arrowhead Pharmaceuticals

Terminated

A Study of ARC-521 Injection in Normal Adult Volunteers and Patients With Chronic Hepatitis B (CHB)

Hepatitis B

New Zealand
Alexion Pharmaceuticals

Terminated

Natural History Study to Characterise the Course of Disease Progression in Participants With Mucopolysaccharidosis Type IIIB

MPS IIIB (Sanfilippo B Syndrome)

Spain, United States, Brazil, United Kingdom, Portugal, Italy
Anthera Pharmaceuticals

Completed

SOLUTION: Study of Oral Liprotamase Unit-Matched Therapy Of Non-Porcine Origin in Patients With Cystic Fibrosis

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States, Hungary, Israel, Poland, Spain, Canada, Czechia
Arrowhead Pharmaceuticals

Terminated

A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Alpha-1 Antitrypsin Deficiency

Australia, Netherlands, Germany, United Kingdom
Sunesis Pharmaceuticals

Completed

Safety and Efficacy Clinical Study of SNS-595 in Patients With Advanced Small Cell Lung Cancer

Small Cell Lung Cancer | Carcinoma, Small Cell

United States, Canada
Alexion Pharmaceuticals

Completed

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 (Sebelipase Alfa) in Adult Subjects With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | LAL-Deficiency | Cholesterol Ester Storage Disease (CESD)

France, United Kingdom, United States, Canada, Czechia
Alnylam Pharmaceuticals

Completed

ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)

Amyloid Neuropathies | Amyloid Neuropathies, Familial | Amyloidosis, Hereditary | Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) | Amyloidosis, Hereditary, Transthyretin-Related | Familial Transthyretin Cardiac Amyloidosis

United States, France, Italy, Spain, Canada, Germany, Belgium, Sweden, United Kingdom
ASLAN Pharmaceuticals

Completed

A Study of Varlitinib in Japanese Subjects With Advanced or Metastatic Solid Tumours

Advanced or Metastatic Solid Tumors | Advanced or Metastatic Biliary Tract Cancer

Japan
Vanda Pharmaceuticals

Completed

An Observational Study to Investigate the Effects of Rapid Transmeridian Travel

Jet Lag Disorder

United States
Alnylam Pharmaceuticals

Completed

A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)

Acute Intermittent Porphyria

United States, United Kingdom, Sweden
Prolong Pharmaceuticals

Completed

A Study of EPEG in Beta Thalassemia Patients

Beta-Thalassemia

Thailand
Prolong Pharmaceuticals

Withdrawn

Safety and Pharmacokinetics of SANGUINATE™ in Sickle Cell Disease (SCD) Patients

Sickle Cell Disease

Israel
ASLAN Pharmaceuticals

Withdrawn

Study of Varlitinib Plus Capecitabine in Patients With Advanced or Metastatic Biliary Tract Cancer

Advanced or Metastatic Biliary Tract Cancer
Prolong Pharmaceuticals

Completed

Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis

Anemia, Sickle Cell

United States
Anthera Pharmaceuticals

Completed

SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic Fibrosis (SIMPLICITY)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Vanda Pharmaceuticals

Unknown

Study to Assess the Efficacy of VLY-686 in Relieving Symptoms of Gastroparesis

Gastroparesis

United States
Ferring Pharmaceuticals

Completed

Efficacy and Safety of Prepopik® in Children for Overall Colon Cleansing in Preparation for Colonoscopy (Prepopik PREA)

Need for Bowel Preparation

United States
Aerie Pharmaceuticals

Completed

Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution

Ocular Hypertension | Open Angle Glaucoma

United States
Alexion Pharmaceuticals

Terminated

A Open Label Study in Previously Studied, SBC-103 Treatment Naïve MPS IIIB Subjects to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 Administered Intravenously (CL01-T)

Mucopolysaccharidosis III, Type B (MPS IIIB) | Sanfilippo B

United Kingdom
Aerie Pharmaceuticals

Completed

Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Hope Pharmaceuticals

Terminated

Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage

Subarachnoid Hemorrhage

United States
Merrimack Pharmaceuticals

Completed

Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment

Colorectal Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | Triple Negative Breast Cancer | Squamous Cell Head and Neck Cancer

United States
Jazz Pharmaceuticals

Withdrawn

Pharmacokinetic and Pharmacodynamic Assessment of Treatment With CPX-351 (Cytarabine: Daunorubicin) Liposome for Injection in Acute Leukemias and MDS Patients With Moderate Hepatic Impairment

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS)

United States
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Paroxysmal Nocturnal Hemoglobinuria
Lyric Pharmaceuticals

Completed

Efficacy, Safety, and Pharmacokinetics (PK) Study of Ulimorelin in Patients With Enteral Feeding Intolerance (EFI): The PROMOTE Trial (PROMOTE)

Enteral Feeding Intolerance (EFI)

United States, Spain, Netherlands
Merrimack Pharmaceuticals

Unknown

A Study Evaluating MM-310 in Patients With Solid Tumors

Soft Tissue Sarcoma | Small Cell Lung Cancer | Ovarian Cancer | Squamous Cell Carcinoma of the Head and Neck | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Gastric Carcinoma | Solid Tumors | Pancreatic Ductal Adenocarcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Prostate Adenocarcinoma

United States
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Spain, Sweden, United Kingdom, Netherlands
Jazz Pharmaceuticals

Completed

Trial of CPX-351 in Newly Diagnosed Elderly AML Patients

Acute Myeloid Leukemia

United States, Canada
Allena Pharmaceuticals

Completed

Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones

Nephrolithiasis | Kidney Stones | Hyperoxaluria | Secondary Hyperoxaluria | Dietary Hyperoxaluria

United States
Gem Pharmaceuticals

Completed

Efficacy and Safety Study of GPX-150 to Treat Soft Tissue Sarcoma

Soft Tissue Sarcoma

United States
Immune Pharmaceuticals

Unknown

Evaluation of Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of Bertilimumab in Patients With Active Moderate to Severe Ulcerative Colitis

Ulcerative Colitis, Active Severe | Ulcerative Colitis, Active Moderate

Israel
KAI Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of Etelcalcetide in Hemodialysis Patients With Secondary Hyperparathyroidism

Hyperparathyroidism, Secondary

United States, Australia
Regeneron Pharmaceuticals

Completed

Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection) (RE-VIEW)

Age - Related Macular Degeneration (AMD)

United States
Threshold Pharmaceuticals

Terminated

Phase I TH-302 Plus Gemcitabine Plus Nab-Paclitaxel in Pancreatic Cancer

Pancreatic Cancer

United States
Endo Pharmaceuticals

Completed

AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease

Advanced Dupuytren's Disease

United States
Endo Pharmaceuticals

Completed

Safety and Efficacy Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease (JOINT-I)

Advanced Dupuytren's Disease

United States

Clinical Trials Sponsored by Somaxon Pharmaceuticals

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