Clinical Trials Sponsored by TiGenix n.v.

Total 1535 results

Janssen Vaccines & Prevention B.V.

Completed

Safety and Efficacy Study of Vaccine Schedule With Ad26.Mos.HIV and MVA-Mosaic in Human Immunodeficiency Virus (HIV)-Infected Adults

Human Immunodeficiency Virus

Thailand
Wissenschaftliches Institut Bethanien e.V

Completed

The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation

Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Obesity Hypoventilation Syndrome | Restrictive Lung Disease | Hypoventilation Syndrome

Germany
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate the Safety and Immunogenicity of Seasonal Influenza Vaccine and an Adenovirus Serotype 26- Based Vaccine Encoding for the Respiratory Syncytial Virus Pre-fusion F Protein (Ad26.RSV.preF), With and Without Co-administration, in Adults Aged 60 Years and Older in Stable Health

Healthy

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study to Assess the Safety, Reactogenicity and Immunogenicity of a Trivalent Inactivated Poliovirus Vaccine (IPV) Based on Sabin Strains Compared to Conventional Salk IPV in a 6, 10 and 14 Weeks of Age Immunization Schedule

Healthy

Philippines
Janssen Vaccines & Prevention B.V.

Completed

Safety, Tolerability and Immunogenicity Study of Different Vaccine Schedules With Ad26.Mos.HIV and Clade C Glycoprotein (gp)140 in Healthy Human Immunodeficiency Virus (HIV)-Uninfected Adults

Healthy

United States
Wissenschaftliches Institut Bethanien e.V

Completed

Inspiratory Muscle Training During Right-heart Catheterization

Respiratory Muscle Training | Right-heart Hemodynamics | Inspiratory Resistance

Germany
Wissenschaftliches Institut Bethanien e.V

Completed

Travelling in Patients With Sleep Related Breathing Disorders

Travel, Sleep Related Disorder
Medical Enterprises Europe B.V.

Withdrawn

SHTC - EUROPE-1 Synergo Hyperthermia-Chemotherapy by European Urologists' Research Operation Preserving Evolution Study I (SHTC-EUROPE-1)

Neoplasms | Urologic Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Urologic Diseases | Urinary Bladder Diseases | Urinary Bladder Neoplasms
N.M. Wulffraat

Completed

Treatment of Steroid Resistant GVHD by Infusion MSC (MSCforGVHD)

Graft-versus-host-disease

Netherlands
Allergan S.A. DE C.V..

Completed

Comparison of Efficacy & Tolerability Between Ganfort vs Krytantek in Mexican Patients With Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Glaucoma Primary Open Angle

Mexico
Foerderinitiative Pharmazeutische Betreuung e.V.

Unknown

Pharmaceutical Care of Patients With Impaired Mobility in a Model-region of Decreasing Supply of Medical Services

Diabetes
Probiomed S.A. de C.V.

Unknown

TREatment of degeNerative and Neoplastic Diseases With Rituximab (TREND)

Diffuse Large B Cell Lymphoma

Mexico
UNC Lineberger Comprehensive Cancer Center
AstraZeneca; Rgenix, Inc.

Recruiting

Abequolixron (RGX-104) and Durvalumab in Lung Cancer

Non-Small Cell Lung Cancer

United States
AiCuris Anti-infective Cures AG
Impatients N.V. trading as myTomorrows

Available

Expanded Access Intermediate Size Treatment Protocol: Pritelivir for Immunocompromised Subjects With Treatment Resistant Herpes Simplex Virus Type 1 or 2

HSV
Johnson & Johnson Pharmaceutical Research & Development...
Janssen Pharmaceutica N.V., Belgium

Completed

A Safety and Dose-finding Study of JNJ-26481585 for Patients With Advanced Solid Malignancies and Lymphoma.

Neoplasms | Lymphoma

United Kingdom
ATRO Medical B.V.
Avania

Recruiting

AIR (Artificial Implant to Restore the Medial Meniscus Function)2 Clinical Investigation (AIR2)

Knee Injuries and Disorders

Netherlands
L.V. Prasad Eye Institute

Not yet recruiting

To Evaluate the Clinical Safety and Efficacy of Limbal Stem Cell for Treatment of Superficial Corneal Pathologies".

Corneal Scars and Opacities
Wissenschaftliches Institut Bethanien e.V

Recruiting

Respiratory Muscle Strength in Patients With Obesity Hypoventilation Syndrome (OHS) or With a Precursor of the Disease

Obesity Hypoventilation Syndrome

Germany
Janssen Vaccines & Prevention B.V.

Completed

A Safety, Tolerability and Immunogenicity Study of 2 Different Regimens of Tetravalent Ad26.Mos4.HIV Prime Followed by Boost With Tetravalent Ad26.Mos4.HIV Along With Either Clade C gp140 Plus Adjuvant OR With a Combination of Mosaic and Clade C gp140 Plus Adjuvant in Healthy HIV Uninfected Adults (IPCAVD-012)

Healthy

United States, Rwanda, Kenya
Wissenschaftliches Institut Bethanien e.V

Completed

Clinical Course and Treatment of COVID-19 Inpatients in Hospital

COVID-19

Germany
L.V. Prasad Eye Institute

Completed

Ologen® Collagen Matrix Versus Mitomycin-C in Patients With Juvenile-onset Open Angle Glaucoma

Open Angle Glaucoma

India
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Adenovirus Serotype 26 Based Respiratory Syncytial Virus Pre-fusion (Ad26.RSV.Pre-F) Vaccine in RSV-Seronegative Toddlers 12 to 24 Months of Age

Respiratory Syncytial Virus

Canada, United Kingdom, Spain, Brazil, Sweden, Poland, Australia, Finland
Janssen Vaccines & Prevention B.V.

Completed

A Study of an Ad26.RSV.PreF-based Regimen at the End of Shelf-life in Adults Aged 60 to 75 Years

Respiratory Syncytial Virus Prevention

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate Dose Levels of Ad26.COV2.S Administered as a Two-dose Schedule in Healthy Adults

COVID-19 Prevention

United States, Germany, Brazil, Poland, South Africa
Janssen Vaccines & Prevention B.V.

Completed

A Study of an Ad26.RSV.preF-based Regimen in the Prevention of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)-Confirmed Respiratory Syncytial Virus (RSV)-Mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older (CYPRESS)

Respiratory Tract Diseases | Respiratory Syncytial Viruses

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults (ENSEMBLE 2)

Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19

United States, United Kingdom, Belgium, Spain, France, Germany, Philippines, Brazil, Colombia, South Africa
Orthox Limited
Avania B.V.

Terminated

FibroFix Cartilage P Knee Implant Study (FFLEX)

Osteoarthritis, Knee

United Kingdom, Hungary
Janssen Vaccines & Prevention B.V.

Completed

An Exploratory Study to Evaluate the Prophylactic Efficacy of a Single Immunization of Ad26.RSV.preF Against Respiratory Syncytial Virus Infection in a Virus Challenge Model in Healthy 18 to 50 Year-old Adults

Healthy

United Kingdom
TripleMed B.V.
Fakkel bvba

Completed

ANEUFIX for Endoleaks Type II (ACP-T5)

Abdominal Aortic Aneurysm

Netherlands
L.V. Prasad Eye Institute

Unknown

Limbus-derived Stem Cells for Prevention of Postoperative Corneal Haze

Corneal Scars and Opacities

India
Wissenschaftliches Institut Bethanien e.V

Completed

Impact of CPAP Therapy in Obstructive Sleep Apnea on Parameters of Nocturnal Pulse Wave Analysis

Obstructive Sleep Apnea

Germany
Wissenschaftliches Institut Bethanien e.V

Completed

Cryobiopsy vs. VATS in Diagnosis of Interstitial Lung Diseases

Interstitial Lung Disease

Germany
Medical Enterprises Europe B.V.

Withdrawn

RITE-EUROPE (Radiofrequency-Induced Thermochemotherapy Effect-EUROPE)

Bladder Cancer
Janssen Vaccines & Prevention B.V.

Completed

A Safety and Immunogenicity Study of Heterologous and Homologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants

Healthy

United States
AbGenomics B.V Taiwan Branch

Terminated

A Study of AbGn-168H in Patients With Steroid Refractory Acute Graft-vs-Host Disease After Donor Stem Cell Transplant

Acute Graft Versus Host Disease

United States
Revent Medical International B.V.

Completed

Feasibility Study of the ReVENT Sleep Apnea System (REV-001)

Obstructive Sleep Apnea (OSA)
AbGenomics B.V Taiwan Branch

Withdrawn

A Study Evaluating the Efficacy and Safety of Neihulizumab vs "Conventional Treatment" to Treat Sr-aGvHD

Steroid-refractory aGvHD Subsequent to Allogeneic Hematopoietic Cell Transplantation

United States
AbGenomics B.V Taiwan Branch

Completed

A Study of Multiple Doses of AbGn-168H by Intravenous Infusion in Patients With Moderate to Severe Chronic Plaque Psoriasis

Moderate to Severe Chronic Plaque Psoriasis

United States
Refocus Ocular Europe, B.V.

Completed

Trial of the PresView Implant for the Improvement of Near Vision in Presbyopic Patients

Presbyopia

United Kingdom
AbGenomics B.V Taiwan Branch

Completed

Phase IIa Study of Multiple Doses of AbGn-168H by iv Infusion in Moderate to Severe Chronic Plaque Psoriasis Patients (AbGn-168H)

Moderate to Severe Chronic Plaque Psoriasis

United States
Aeon Astron Europe B.V.

Unknown

Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Trabeculectomy: A Study in Germany

Open-angle Glaucoma

Germany
Bayer
Biogen Netherlands B.V; Novartis Europharm Limited; Merck Europe B.V.

Not yet recruiting

An Observational Study to Learn About the Interferon-beta Exposure of Pregnant Women During the Second and Third Trimester in Finland and Sweden (INFORM)

Multiple Sclerosis (MS)

Sweden, Finland
H. Lee Moffitt Cancer Center and Research Institute
Trod Medical N.V.

Completed

Focal Prostate Radio-Frequency Ablation

Prostate Cancer

United States
Digna Biotech S.L.
University of Navarra; Porphyria Centre Sweden; UniQure N.V.

Completed

Observational Study of Acute Intermittent Porphyria Patients

Acute Intermittent Porphyria

Spain
Janssen Pharmaceutica N.V., Belgium
Agentschap voor Innovatie door Wetenschap en Technologie

Completed

The Effect of Nicotine on Arousal, Cognition and Social Cognition in Young and Elderly Healthy Subjects.

Schizophrenia | Cognition Disorders
Janssen Pharmaceutica N.V., Belgium
Agentschap voor Innovatie door Wetenschap en Technologie

Completed

The Effect of Nicotine on Arousal, Cognition and Social Cognition in Schizophrenic Patients

Schizophrenia | Cognition Disorders
BAAT Medical Products B.V.

Recruiting

SINEFIX-2022 Pilot Phase

Rotator Cuff Tears (RCTs)

Germany
Maastricht University
BioActor B.V.

Recruiting

The Effect of Sweet Orange and Pomegranate Extract Supplementation on Exercise Capacity in Middle-aged Adults (Actiful2)

Exercise Capacity

Netherlands
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate a Range of Dose Levels of an Adenovirus Serotype 26 (Ad26.RSV.preF)-Based Vaccine in Older Adults

Healthy

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older (EVERGREEN)

Respiratory Syncytial Viruses | Lower Respiratory Tract Disease

United States, Taiwan, Thailand, Canada, Poland, United Kingdom, Brazil, Chile, New Zealand, Estonia, Finland, South Africa, Australia, China

3

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