Search clinical trials for: 14C radio-labeled

Total 535 results

Astellas Pharma Global Development, Inc.

Completed

A Study to Look at How a Single Oral Dose of 14C-OSI-906 is Absorbed, Broken Down and Eliminated in the Body

Advanced Solid Tumors | Pharmacokinetics of 14C-OSI-906

United States
Astellas Pharma Global Development, Inc.

Withdrawn

A Study to Investigate the Absorption, Metabolism and Excretion of [14C]ASP8273 in Subjects With Solid Tumors

Solid Tumors | Epidermal Growth Factor Receptor (EGFR) Mutations
Shenzhen TargetRx, Inc.
The First Affiliated Hospital of Soochow University

Not yet recruiting

TGRX-326 Pharmacokinetic Mass Balance

Non Small Cell Lung Cancer
Cerevel Therapeutics, LLC

Not yet recruiting

A Trial to Assess the Absorption, Metabolism, Excretion, and Mass Balance of [14C]-Darigabat After a Single Oral Dose in Healthy Male Participants

Healthy Participants

United States
Celgene

Not yet recruiting

A Study to Evaluate the Drug Levels, Metabolism and Excretion, and Absolute Bioavailability of BMS-986365 in Healthy Male Participants

Healthy Volunteers

United States
Calico Life Sciences LLC
AbbVie

Recruiting

Study of [14C] ABBV-CLS-7262 in Healthy Male Volunteers Following Single Oral Dose Administration

Healthy Volunteer

United States
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study to Evaluate the Mass Balance of [14C]SHR7280 in Healthy Adult Volunteers

Assisted Reproduction

China
Pfizer

Not yet recruiting

A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.

Healthy Participants
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Mass Balance of [14C] SY-5007 in Healthy Adult Male Subjects in China

Healthy Subjects

China
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

M1774 Human Mass Balance Study (DDRIVER Solid Tumors 303)

Solid Tumor

Hungary
Viracta Therapeutics, Inc.

Recruiting

A Mass Balance Study of [14C]-Nanatinostat and Relative Bioavailability Study of Nanatinostat in Patients With Advanced Cancers

Advanced Cancer

Spain
Denali Therapeutics Inc.

Recruiting

A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants

Healthy Volunteers

United States
Wageningen University
TNO; Gelderse Vallei Hospital; Bonumose, Inc.

Recruiting

Mass Balance of Orally Administered [14C] (3S,4S,5R)-1,3,4,5,6-pentahydroxy-hexan-2-one (TrueCal)

Energy Intake | Energy Metabolism

Netherlands
Abbisko Therapeutics Co, Ltd

Recruiting

A Mass Balance Study of [14C]ABSK021

Healthy Subjects

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Mass Balance Study of TQB3616

Breast Cancer

China
Eli Lilly and Company
Loxo Oncology, Inc.

Not yet recruiting

A Study of [14C]-LOXO-783 in Healthy Adult Participants

Healthy

United States
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Drug Levels, Physical and Chemical Changes, and Removal of BMS-986196 in Healthy Male Participants

Healthy Male Volunteers

United States
Takeda

Recruiting

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Solid Tumors

Hungary
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study of the Absorption, Metabolism and Excretion of [14C]XZP-3621 in Human

Healthy Volunteers

China
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Recruiting

The Mass Balance Study of [14C]JT001

Healthy Subjects

China
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

Substance Balance Study of [14C]ZX-7101A in Healthy Adult Male Subjects in China

Influenza, Human
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

A Clinical Trial of XZP-3287 for Material Balance

Healthy Male Subjects

China
Chipscreen Biosciences, Ltd.

Recruiting

Mass Balance Study of [14C]Chiauranib

Small Cell Lung Cancer

China
Impact Therapeutics, Inc.

Not yet recruiting

A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects

Solid Tumor
Icahn School of Medicine at Mount Sinai

Recruiting

Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer

Breast Cancer | Metastasis

United States
Angion Biomedica Corp
Quotient Sciences

Recruiting

A Study to Assess the Absorption, Metabolism and Excretion of [14C]-ANG-3777

Healthy

United Kingdom
L'Oreal

Recruiting

Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE, Under Real Sun Exposure

Real Life Pigmentation

India
Incyte Corporation

Active, not recruiting

A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants

Healthy Participants

United Kingdom
Eli Lilly and Company

Completed

A Study of Carbon-14-Labelled [14C] LY3473329 in Healthy Male Participants

Healthy

United Kingdom
Boehringer Ingelheim

Active, not recruiting

A Study in People With Advanced Cancer to Test How BI 907828 is Processed in the Body

Solid Tumors

Hungary
AstraZeneca
Quotient Sciences

Completed

An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604

Asthma

United Kingdom
Arcus Biosciences, Inc.
Gilead Sciences

Completed

A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Compound in the Treatment of Cancer

Healthy Participants

Netherlands
Biogen

Completed

A Study to Look at How a Single Oral Dose of Carbon-14-Labelled [14C] BIIB091 Moves Through and is Processed by the Body in Healthy Male Participants (Mass Balance)

Healthy Volunteer

United States
Rivus Pharmaceuticals, Inc.

Completed

A Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-HU6

Healthy

United States
Basilea Pharmaceutica

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
Pfizer

Completed

A Study to Learn About Effect of Sisunatovir in Healthy Adult Male Participants

Respiratory Syncytial Virus Infections

United States
Pfizer

Completed

A Study to Understand What the Body Does to the Study Medicine Called PF-07220060 When Taken by Healthy Adults

Healthy Participants

Netherlands
Celgene

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion of Orally Administered [14C]-BMS-986368 in Healthy Male Participants

Healthy Volunteers

United States
AbbVie

Completed

A Study to Assess the Mass Balance of [14C] ABBV-552 in Healthy Male Participants Following Single Oral Dose Administration

Healthy Volunteer

United States
Cassava Sciences, Inc.

Completed

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-Simufilam Following a Single Oral Dose in Healthy Male Subjects

Metabolism | Absorption | Excretion

United States
Kyowa Kirin, Inc.

Completed

Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-KW-6356

Healthy Male Subjects

United States
Bristol-Myers Squibb

Withdrawn

A Study of Absorption, Metabolism, and Elimination CC-90010 in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Spain
Guangdong Raynovent Biotech Co., Ltd

Completed

Mass Balance Study of [14C]RAY1216 in Healthy Adult Male Subjects in China

Pharmacokinetics

China
Bayer

Completed

A Study to Learn How BAY2927088 is Taken up and Handled by the Body in Healthy Male Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

Netherlands
Eli Lilly and Company

Completed

A Study of Carbon-14-Labeled [14C]-LY3549492 in Healthy Participants

Healthy Male

United Kingdom
Oystershell NV

Completed

Safety and Efficacy of a Head Lice Shampoo

Head Lice

Germany
Eli Lilly and Company

Completed

A Phase I Study of LY3502970 in Healthy Participants

Healthy

United States
Epizyme, Inc.

Completed

Open-Label, Multi-Center, Two-Part, Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors

Follicular Lymphoma | Marginal Zone Lymphoma | Advanced Solid Tumors | Mantle-Cell Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal Lymphoma

United Kingdom
Guangzhou Lupeng Pharmaceutical Company LTD.

Completed

The Mass Balance Study of LP-168 in Healthy Subjects

Clinical Pharmacology

China
Kazia Therapeutics Limited
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects

Healthy

United Kingdom

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