Search clinical trials for: Adalimumab trough level

Total 8490 results

Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Recruiting

Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring (ADDORA)

Rheumatoid Arthritis

Netherlands
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Active, not recruiting

Using Adalimumab Serum Concentration to Choose a Subsequent Biological DMARD in Rheumatoid Arthritis Patients Failing Adalimumab Treatment (ADDORA-switch)

Rheumatoid Arthritis

Netherlands
University Hospital, Ghent
KU Leuven

Completed

A Non-inferiority Study on Dose Reduction of Adalimumab in Psoriasis Patients Who Are Overtreated

Psoriasis

Belgium
Radboud University Medical Center
Erasmus Medical Center

Active, not recruiting

Lengthening Adalimumab Dosing Interval in Quiescent Crohn's Disease Patients (LADI)

Crohn Disease | Crohn Disease in Remission

Netherlands
AbbVie

Completed

A Prospective Non-interventional Multicenter Study to Evaluate the Effectiveness of Adalimumab in Korean Patients With Ulcerative Colitis (UC) and Identify Potential Predictors of Clinical Response in Routine Clinical Practice (EUREKA)

Ulcerative Colitis

Korea, Republic of
Oslo University Hospital

Completed

Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease

Norway
Universitaire Ziekenhuizen KU Leuven

Unknown

Adalimumab Trough Concentrations in Crohn's Disease: A Pilot Pharmacokinetic Study

Crohn's Disease

Belgium
Alexandria University

Recruiting

Effect of Obesity on Cyclosporine Blood Trough Level in Nephrotic Syndrome Patients

Nephrotic Syndrome

Egypt
Boston Medical Center
American Society of Health-System Pharmacists

Recruiting

Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis (TDM-RA)

Rheumatoid Arthritis

United States
McMaster University
The Physicians' Services Incorporated Foundation

Recruiting

Vancomycin Dosing for Serious MRSA Infections: A Non-inferiority Randomized Trial of Trough Level Versus AUC/MIC

MRSA

Canada
Beth Israel Deaconess Medical Center
Veloxis Pharmaceuticals

Not yet recruiting

Efficacy of Envarsus XR and Digital Health Technology in Reducing Tacrolimus Fluctuation and Frequency of Dose Changes

Medication Adherence | Renal Transplant
Hospital Universitario La Paz

Recruiting

Correlation of Serum Adalimumab Levels at an Administration of 40 mg Weekly vs 80 mg Every Two Weeks (IntnsificADA)

Inflammatory Bowel Diseases

Spain
University Hospital, Montpellier

Recruiting

Interest of the Dosage of Adalimumab Serum Levels in Crohn's Disease Patients for Prevention of Postoperative Recurrence (ADAPT)

Crohn Disease

France
University Hospital, Montpellier

Recruiting

Comparison of Trough Level- and Clinical-based Spacing of Infliximab Infusions in Patients With IBD in Deep Remission (SPACIFIX)

Inflammatory Bowel Diseases

France
Singapore General Hospital

Active, not recruiting

Efficacy of Achieving Early Target Trough Levels of Tacrolimus Using CYP3A5 Guided Dosing Versus Weight-based Dosing in a Multi-ethnic Population of Kidney Transplant Recipients in Singapore

Kidney Transplant Rejection | Kidney Transplant; Complications

Singapore
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Completed

Adalimumab Dose Reduction Aiming Low Serum Concentration With Control of Disease Activity (ADDORA-low)

Rheumatoid Arthritis

Netherlands
Hospital San Carlos, Madrid
Merck Sharp & Dohme LLC; Hospital Universitario Ramon y Cajal; Complejo Hospitalario... and other collaborators

Completed

Golimumab Trough Levels in Patients With Ulcerative Colitis (GLMLEVEL)

Ulcerative Colitis

Spain
University Hospital, Basel, Switzerland

Completed

Characterization of Adalimumab Concentrations in Pediatric Patients With Inflammatory Rheumatic Disease With and Without Methotrexate (ADA in PiRD)

Rheumatic Diseases

Switzerland, Germany
Schneider Children's Medical Center, Israel

Completed

Pediatric Crohn's Disease AdalImumab Level-based Optimization Treatment (PAILOT) Trial

Crohn's Disease

Israel
CR-CSSS Champlain-Charles-Le Moyne

Completed

Vancomycin Dose Adjustments Comparing Trough Levels to The AUC/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population (VancoDATABayes)

Adult | Vancomycin | Area Under Curve

Canada
Guy's and St Thomas' NHS Foundation Trust
Merck Sharp & Dohme LLC

Completed

Study of the Golimumab Exposure-Response Relationship Using Serum Trough Levels (GO-LEVEL)

Ulcerative Colitis

United Kingdom
Novartis Pharmaceuticals

Terminated

Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma Concentrations (MACS1148)

CML | Philadelphia Chromosome Positive (Ph+) | Chronic Myelogenous Leukemia Chronic Phase(CML-CP) Patients With Low Imatinib Trough Levels

United States
University of Utah
Boston University; University of Pennsylvania; Northwestern University; Columbia... and other collaborators

Completed

ACEI or ARB and COVID-19 Severity and Mortality in US Veterans

Hypertension | COVID

United States
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Association of Cefepime Trough Levels With Clinical Efficacy and Neurotoxicity in Patients With Febrile Neutropenia

Pharmacokinetics | Pharmacodynamics | Cefepime

Belgium
Columbia University
Veloxis Pharmaceuticals

Active, not recruiting

Envarsus on the Effect of Total Tacrolimus Dose/Trough Level Ratio on Renal Function (eGFR) in Kidney Transplantation

Renal Transplant Rejection | Kidney Transplant Failure and Rejection

United States
Southern Medical University, China
Third Affiliated Hospital, Sun Yat-Sen University; 181 Central Hospital of...

Completed

Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation.

Transplantation

China
AbbVie

Completed

A Phase 4 Trial Assessing the ImPact of Residual Inflammation Detected Via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remission Rheumatoid ArThritis (RA) Subjects (PREDICTRA)

Rheumatoid Arthritis | Musculoskeletal and Connective Tissue Diseases

United States, Australia, Austria, Canada, France, Germany, Greece, Hungary, Ireland, Italy, Netherlands, Spain, Sweden, United Kingdom
Southeast University, China

Completed

The Influencing Factors of Vancomycin Trough Level and the Rate Achieving the Target Trough Level

Vancomycin
Medical University of Vienna

Completed

The Vienna Prograf and Endothelial Progenitor Cell Extension Study (PEP-X)

Renal Failure | Immunosuppression
Universitaire Ziekenhuizen KU Leuven

Completed

Evaluation of the Dosing Regimen of Vancomycin in Pediatric Patients

Gram-Positive Bacterial Infections

Belgium
Versailles Hospital

Completed

A Prospective Randomized Phase II Study Evaluating the Monitoring of Imatinib Mesylate Plasmatic Through Level in Patients Newly Diagnosed With CP-CML (OPTIMIMATINIB)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

France
Chulalongkorn University

Unknown

The Study of Voriconazole Trough Level in the First Two Weeks After Administration in King Chulalongkorn Memorial Hospital.

Fungal Infection | Voriconazole

Thailand
Centre Francois Baclesse
University Hospital, Caen

Terminated

Relation Between Safety Endpoints and Everolimus Trough Blood Level in Advanced Renal Cell Carcinoma

Renal Cell Carcinoma

France
Cedars-Sinai Medical Center

Unknown

Individualized Infiximab Dosing-Proof of Concept Study

Inflammatory Bowel Diseases

United States
Macquarie University, Australia

Unknown

Effect of Enzalutamide Dose Reduction on Fatigue, Cognition, and Drug Trough Levels in Patients With Prostate Cancer (EFFECT)

Prostate Cancer

Australia
AbbVie

Terminated

Fecal Calprotectin Levels, Quality of Life, and Workability in Patients Suffering From Ulcerative Colitis Under Adalimumab Therapy - AdaProQuo (AdaProQuo)

Moderate to Severe Ulcerative Colitis
Universitaire Ziekenhuizen KU Leuven
Pfizer

Completed

An Observational Monocentric Study Investigating the Association Between Trough Serum Levels of Etanercept, Antibodies Towards Etanercept and Its Effectiveness in Psoriasis Patients (DERM)

Psoriasis
Seoul National University Hospital

Unknown

Influence of CYP3A5 Polymorphism on Liver Function Abnormality and the Trough Level Change After Conversion

Liver Dysfunction

Korea, Republic of
Klinikum Westbrandenburg GmbH

Unknown

TOPIT; Trough Level Optimized Pediatric Inflammatory Bowel Disease Therapy: A Multicenter Study Comparing Effectiveness of Trough Level Optimized Infliximab Maintenance Therapy With Standard Dosing Regimen of Pediatric Patients With Crohn's Disease (TOPIT)

Pediatric Crohns Disease
Groupe d'Etude Therapeutique des Affections Inflammatoires...

Completed

Study Investigating Tailored Treatment With Infliximab for Active Crohn's Disease (TAILORIX)

Crohn's Disease

France
Chulalongkorn University

Unknown

First Tacrolimus Dose Trough Level is Better Than CYP3A5 Genotyping in Tacrolimus Dose Prediction

Kidney Transplantation Recipients

Thailand
AbbVie (prior sponsor, Abbott)
Raffeiner GmbH

Completed

Reveal the Level of Anxiety in Patients With Crohn's Disease Receiving Adalimumab (RELAX)

Anxiety | Severe Crohn's Disease

Austria
Asan Medical Center

Terminated

Voriconazole Trough Plasma Levels : Genetic Polymorphism, Efficacy, Safety in Patients With Hematologic Malignancy

Invasive Fungal Infection

Korea, Republic of
Chulalongkorn University

Completed

Concentration-controlled Therapy of Mycophenolate Mofetil (MMF) in Proliferative Lupus Nephritis

Lupus Nephritis

Thailand
CSL Behring

Completed

Efficacy and Safety of Vivaglobin® in Previously Untreated Patients With Primary Immunodeficiency

Common Variable Immunodeficiency | Agammaglobulinemia

Canada, Germany, Italy, Spain
Hannover Medical School

Completed

Patient Education After Lung Transplantation Via Tablet Computers Versus Conventional Education

Lung Transplantation

Germany
Halic University

Not yet recruiting

The Relationship Between Body Perception and Self-Esteem Level and Quality of Life in Adolescent Idiopathic Scoliosis

Quality of Life | Scoliosis; Adolescence | Self Esteem

Turkey
Duke University

Not yet recruiting

Integration of Mindfulness and Acupuncture After Spine Surgery (I-MASS)

Laminectomy | Single Level Spinal Fusion | Discetomy

United States
Assiut University

Recruiting

Investigating Microparticle Levels In Filtered Packed Red Blood Cell Units

Packed Red Cells Causing Adverse Effects in Therapeutic Use

Egypt
Riphah International University

Recruiting

Moderate Intensity Soleus Pushups Versus Sustained Soleus Pushups on Blood Glucose Level Among Young Population

Health Behavior

Pakistan

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