Search clinical trials for: Advanced/metastatic solid malignancies, TMB high
Total 28585 results
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Innovent Biologics (Suzhou) Co. Ltd.CompletedAdvanced/Metastatic Solid MalignanciesUnited States
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Marengo Therapeutics, Inc.RecruitingNeoplasms | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Epstein-Barr Virus Infections | Advanced Solid Tumors | Vulvar Neoplasms | Vulvar Diseases | Abdominal Neoplasm | Lung Neoplasm | Papillomavirus Infection | Genital Neoplasm, FemaleUnited States, Canada
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Medicenna Therapeutics, Inc.Merck Sharp & Dohme LLCRecruitingClear Cell Renal Cell Carcinoma | Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Solid Tumor | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Skin Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Primary Peritoneal Cancer | Endometrial Carcinoma and other conditionsUnited States, Australia, Korea, Republic of, Canada
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Institut BergoniéBayer; Merck KGaA, Darmstadt, GermanyRecruitingHepatocellular Carcinoma | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Soft-tissue Sarcoma | Urothelial Carcinoma | Thyroid Cancer | Gastro-enteropancreatic Neuroendocrine Tumor | Biliary Tract Cancer | HPV-Related Carcinoma | Solid Tumor, Adult | Mesotheliomas Pleural | GIST | Renal Carcinoma | Colorectal... and other conditionsFrance
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Capital Medical UniversityDuke UniversityWithdrawn
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Bristol-Myers SquibbCompletedPan TumorUnited States, Puerto Rico, Italy, Argentina, Australia, Belgium, Canada, Chile, Denmark, France, Germany, Netherlands, Poland, Romania, Singapore, Spain, United Kingdom
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Zumutor Biologics Inc.RecruitingColorectal Cancer | Esophageal Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Pancreas Adenocarcinoma | Diffuse Large B Cell Lymphoma | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Biliary Tract Cancer | High Grade Ovarian Serous AdenocarcinomaUnited States
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University of Kansas Medical CenterNot yet recruiting
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ImmuneOncia Therapeutics Inc.Not yet recruitingA Study of Phase2, IMC-001 In Patients With Metastatic Or Locally Advanced TMB-H Solid Tumor (TMB-H)TMB-H | Histologically or Cytologically Proven Metastatic or Locally Advanced Solid Tumors
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7 Hills Pharma, LLCRecruitingMelanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditionsUnited States
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Assistance Publique - Hôpitaux de ParisAction Research GroupNot yet recruitingAortic Valve Stenosis | Heart Valve Diseases
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Shanghai Pharmaceuticals Holding Co., LtdRecruitingAdvanced Solid TumorsChina
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AstraZenecaRecruitingER+ HER2- Advanced Breast Cancer | High-grade Serous Ovarian Cancer (HGSOC)United States, United Kingdom, Korea, Republic of, Australia, Spain
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Memorial Sloan Kettering Cancer CenterRecruitingPancreatic Cancer | Pancreatic Cancer Metastatic | Pancreatic Ductal Adenocarcinoma | Pancreatic Carcinoma | Metastatic Pancreatic Cancer | Metastatic Pancreatic Ductal AdenocarcinomaUnited States
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Daiichi SankyoMerck Sharp & Dohme LLCRecruiting
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A2A Pharmaceuticals Inc.RecruitingTriple Negative Breast Cancer | Endometrial Cancer | High Grade Serous Ovarian CancerUnited States
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Neonc Technologies, Inc.RecruitingMelanoma | Renal Cell Carcinoma | Cervical Cancer | Small Cell Lung Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Merkel Cell Carcinoma | Gastroesophageal Junction... and other conditionsUnited States
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Johns Hopkins All Children's HospitalCannonball Kids' Cancer Foundation; Swim Across America Foundation; Benjamin...Not yet recruitingLymphocytesUnited States
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Molecular Templates, Inc.RecruitingMelanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Microsatellite Instability High | Mismatch Repair DeficiencyUnited States
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Recursion Pharmaceuticals Inc.RecruitingSolid Tumor | APC Gene Mutation | AXIN1 Gene MutationUnited States
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National Institute of Allergy and Infectious Diseases...Baylor College of Medicine; University of Pittsburgh; Ann & Robert H Lurie Children... and other collaboratorsNot yet recruitingInfluenza | Transplantation Infection | Immunization; InfectionUnited States
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Lantern Pharma Inc.Recruiting
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Incyte CorporationRecruitingMelanoma | Hepatocellular Carcinoma (HCC) | Renal Cell Carcinoma (RCC) | Colorectal Carcinoma (CRC) | Microsatellite Instability - High (MSI-H) | Mismatch Repair Deficient (dMMR)United States, Canada, South Africa, Mexico
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Volastra Therapeutics, Inc.RecruitingGastric Adenocarcinoma | Uterine Carcinosarcoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Transitional Cell Carcinoma of Bladder | Colorectal Adenocarcinoma | Gastroesophageal Junction... and other conditionsUnited States
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Incyte CorporationRecruitingAdvanced Solid TumorBrazil, Georgia, Greece, Turkey, Mexico, Romania, South Africa, Hungary, New Zealand, China
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HighField Biopharmaceuticals CorporationRecruiting
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OncoC4, Inc.Avance Clinical; OncoC4 AU Pty LtdRecruitingMelanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Fallopian Tube Cancer | Non Small Cell Lung Cancer | Bile Duct Cancer | Bladder Cancer | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Primary Peritoneal... and other conditionsAustralia
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Novartis PharmaceuticalsRecruitingMSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal CancersJapan, Italy, Spain, Singapore, Belgium, Germany, Korea, Republic of, Sweden, Taiwan, France, Israel, Norway, United States
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ImmuneOnco Biopharmaceuticals (Shanghai) Inc.Shandong Cancer Hospital and InstituteRecruitingBreast Cancer | Small Cell Lung Cancer | Colorectal Cancer | Advanced Solid Tumor | Non-small Cell Lung Cancer | Squamous Cell Cancer of Head and NeckChina
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Kymera Therapeutics, Inc.RecruitingAdvanced Solid Tumors | Acute Lymphocytic Leukemia | Lymphomas | Myeloid MalignanciesUnited States
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Cancer Research UKRoyal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of BirminghamRecruitingMelanoma | Neoplasms by Histologic Type | Lymphoproliferative Disorders | Neoplasms by Site | Cancer | Colorectal Neoplasms | Endometrial Neoplasms | Malignant Neoplasm | MalignancyUnited Kingdom
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Jiangxi Provincial Cancer HospitalRecruitingMetastatic CancerChina
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Cancer Research UKRoyal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of BirminghamRecruitingSolid Tumor | Haematological MalignancyUnited Kingdom
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University of MinnesotaRecruitingSolid Organ TransplantUnited States
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Seoul National University HospitalNot yet recruiting
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Sun Yat-sen UniversityRecruitingSolid Tumor | Intestinal Flora | Immune Checkpoint InhibitorChina
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ProfoundBio US Co.RecruitingOvarian Cancer | Fallopian Tube Cancer | Mesothelioma | Triple Negative Breast Cancer | Endometrial Cancer | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Breast Adenocarcinoma | High Grade Epithelial Ovarian Cancer | Hormone Receptor-positive/Her2 Negative Breast CancerUnited States, China
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University of California, San FranciscoNot yet recruiting
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NextCure, Inc.Merck Sharp & Dohme LLCRecruitingCervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Endometrial Cancer | Colo-rectal Cancer | Advanced or Metastatic Solid Tumors | Microsatellite Instability Low | Microsatellite Instability High | Microsatellite Stable | Head Neck CancerUnited States
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National Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid... and other conditionsUnited States, Puerto Rico
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National Cancer Institute (NCI)RecruitingLocally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid NeoplasmUnited States, Puerto Rico
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Novartis PharmaceuticalsRecruitingCarcinoma, Renal Cell | Carcinoma, Non-Small-Cell Lung | Nasopharyngeal Carcinoma | Carcinoma, Ovarian Epithelial | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Neoplasms | Anal Cancer | Cutaneous Melanoma | Esophagogastric Cancer | Carcinoma, Thymic | High Microsatellite...Italy, Spain, Singapore, Germany, Taiwan, Japan, Canada, Hong Kong, United States
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Monte Rosa Therapeutics, IncRecruitingNSCLC | Prostate Cancer | SCLC | DLBCL | High Grade Neuroendocrine Cancer | L-MYC and N-MYC Amplified Solid Tumors | NSCLC With High or Low L-MYC or N-MYC Expression | HR-positive, HER2-negative Breast CancerUnited States, Canada
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PfizerRecruitingGlioma | Melanoma | Colorectal Cancer | Brain Neoplasms | Non-Small Cell Lung Cancer | Thyroid Cancer | Malignant NeoplasmsCanada, United States
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University of OklahomaVerastem, Inc.RecruitingCervical Cancer | Solid Tumor | Endometrioid Cancer | Mucinous Ovarian Cancer | High Grade Serous Ovarian CancerUnited States
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Australian & New Zealand Children's Haematology...Medical Research Future Fund; Minderoo Foundation; Children's Cancer Institute...RecruitingChildhood Cancer | Relapsed Cancer | Refractory Cancer | Childhood Leukemia | Childhood Solid Tumor | Childhood Brain TumorAustralia
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Revolution Medicines, Inc.RecruitingAdvanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC) | Colorectal Cancer (CRC)United States, Italy, Spain, Malaysia, Korea, Republic of, France, Australia, Thailand, Taiwan, Poland, Singapore, Czechia, Serbia
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Novartis PharmaceuticalsInnovative Therapies For Children with Cancer ConsortiumRecruitingNeuroblastomaGermany, Italy, Singapore, Spain, United States, Australia, France
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Ascentage Pharma Group Inc.RecruitingSarcoma | Nasopharyngeal Carcinoma | Gastric Cancer | B Cell Lymphoma | Mesothelioma | Non Hodgkin Lymphoma | Ovarian Clear Cell Carcinoma | Epithelioid Sarcoma | Castrate Resistant Prostate CancerUnited States