Search clinical trials for: Advanced Glycation Endproduct Inhibitor

Total 82670 results

Assistance Publique - Hôpitaux de Paris
Action Research Group; Bristol-Meyers Squibb & Pfizer

Completed

Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis (ATLANTIS)

Symptomatic Aortic Stenosis | Eligible for Transcatheter Aortic Valve Replacement

France, Germany, Italy, Spain
Albert Einstein College of Medicine
Juvenile Diabetes Research Foundation; National Institutes of Health (NIH)

Completed

Reactive Oxygen Species in the Pathogenesis of Diabetic Complications

Type 1 Diabetes

United States
BioStratum

Completed

Effect of Pyridorin in Patients With Diabetic Nephropathy

Diabetic Nephropathy
BioStratum

Completed

Effect of Pyridorin in Patients With Diabetic Nephropathy

Diabetic Nephropathy
InCor Heart Institute

Recruiting

The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers (RE-AGES)

Coronary Artery Disease | Menopause | Endothelial Dysfunction

Brazil
Medical University of South Carolina

Active, not recruiting

Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

Prostate Cancer

United States
Martin-Luther-Universität Halle-Wittenberg

Completed

Influence of Conditional Workout Postpartum on Arterial Stiffness Among Women With Status After Preeclampsia, Superimposed Preeclampsia or HELLP-syndrome (RedCarRisk)

Preeclampsia | HELLP Syndrome | Superimposed Preeclampsia

Germany
Columbia University

Completed

Advanced Glycation Endproducts and Bone Material Strength in T2D Treated With Pyridoxamine

Diabetes Mellitus, Type 2

United States
vTv Therapeutics

Terminated

Study of Azeliragon in Patients With Mild Alzheimer's Disease and Impaired Glucose Tolerance (Elevage)

Alzheimer Disease

United States, Canada
Medical University of South Carolina

Terminated

Study of Chitosan for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients

Prostate Cancer

United States
Federico II University

Completed

Potential Role of AGEs in Paediatric Allergies

Allergy

Italy
University of Colorado, Denver

Completed

The Relationship Between Advanced Glycation Endproducts and Diabetes

Type 2 Diabetes Mellitus | Diabetic Retinopathy

United States
Maastricht University Medical Center

Completed

Restriction of Dietary AGEs to Prevent Diabetes in Overweight Individuals

Diet | Vascular Function | Insulin Sensitivity/Resistance | Beta-cell Function | Advanced Glycation Endproducts | AGEs

Netherlands
InCor Heart Institute

Unknown

Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease

Coronary Artery Disease Progression

Brazil
Nemours Children's Clinic
Pfizer; Medtronic; Quest Diagnostics-Nichols Insitute

Completed

Statins in Children With Type 1 Diabetes and Hypercholesterolemia

Hypercholesterolemia | Diabetes Mellitus, Insulin-Dependent

United States
Medical University of South Carolina

Withdrawn

Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients

Prostate Cancer

United States
Northwell Health

Withdrawn

The Effect of Sodium-Glucose Cotransporter 2 Inhibitors on Advanced Glycation End Products

Diabetes | SGLT-2 Inhibitors | Advanced Glycation End Products
University Hospital, Clermont-Ferrand

Completed

Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) (SEGA)

Acute Respiratory Distress Syndrome

France
Technological Education Institute of Sterea Ellada
European Union

Completed

Non Invasive Measurement of the Haemodynamic Parameters and of the Advanced Glycation End Products (AGEs) Levels (NONINVASHEMO)

Hemodynamic Instability | Skin and Subcutaneous Tissue Disorders

Greece
Shanghai Jiao Tong University School of Medicine

Unknown

Adavanced Glycated Endproducts and Development of CAD (AGENDA)

Inflammation | Atherosclerosis

China
Radboud University Medical Center
Dutch Heart Foundation; Synvista Therapeutics, Inc

Completed

Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function

Cardiovascular Disease | Physical Activity | Aging | Endothelial Dysfunction

Netherlands
University Hospital, Clermont-Ferrand

Completed

Soluble Forms and Ligands of RAGE in ALI/ARDS (SoLiRAGE). (SoLiRAGE)

Acute Respiratory Distress Syndrome | Acute Lung Injury | Mechanical Ventilation

France
University of Copenhagen
The Ministry of Science, Technology and Innovation, Denmark

Completed

Effects of Advanced Glycation Endproducts on Satiety and Inflammation (AGE-1)

Obesity | Cardiovascular Disease | Insulin Resistance | Type 2 Diabetes

Denmark
Profil Institut für Stoffwechselforschung GmbH
Icahn School of Medicine at Mount Sinai; Heart and Diabetes Center North-Rhine...

Completed

Effects of Food Advanced Glycation Endproducts on Vascular Function in Diabetes

Type 2 Diabetes Mellitus

Germany
University Hospital, Strasbourg, France

Unknown

Quantifying Physical and Biochemical Factors That Contribute to Primary Graft Dysfunction After Lung Transplantation

Primary Graft Dysfunction

France
Synvista Therapeutics, Inc

Completed

The BENEFICIAL Study: Evaluating the Efficacy and Safety of Alagebrium (ALT-711) in Patients With Chronic Heart Failure (BENEFICIAL)

Heart Failure

Netherlands
Synvista Therapeutics, Inc
National Institutes of Health (NIH)

Completed

STRETCH Study: Effect of Distensibility on Endothelial-Dependent Vasoreactivity in Patients With ISH

Cardiovascular Disease

United States
Shenzhen Institute of Advanced Technology, Chinese...

Recruiting

Variation in the Impact of Coffee on the Metabolic Rate

Healthy

China
Ba Yi
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Clinical Study of Irinotecan Hydrochloride Liposome Combined With Capecitabine for Second-line Treatment in Patients With Advanced or Metastatic Biliary Tract Carcinoma

Biliary Tract Carcinoma

China
Wuxi People's Hospital

Recruiting

Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced Solid Tumours

Cancer | PD-L1 Gene Mutation

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations

Non-Small Cell Lung Cancer With HER2- Mutations

China
Blokhin's Russian Cancer Research Center

Recruiting

Neoadjuvant Prolgolimab Monotherapy in Locally Advanced MMR-deficient Colorectal Cancer

Colorectal Cancer

Russian Federation
Khyber Medical University Peshawar

Recruiting

Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet

Inflammation | Obesity | Insulin Resistance | Dyslipidemias | Advance Glycation

Pakistan
Celgene

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma (GOLSEEK-2)

Lymphoma, Follicular

United States, Australia, Brazil, Canada, Chile, France, Germany, Italy, Korea, Republic of, Poland, Spain, Taiwan, United Kingdom
National University Hospital, Singapore

Not yet recruiting

A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers (VALUE-CHECK)

Carcinoma, Hepatocellular | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Oesophageal Cancer | GastroEsophageal Cancer

Singapore
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

M9466 as Single Agent or in Combination With Tuvusertib in Advanced Solid Tumors (DDRiver 501)

Advanced Solid Tumor

United States, Germany
Mayo Clinic

Not yet recruiting

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Cholangiocarcinoma | Refractory Cholangiocarcinoma | Stage III Hilar Cholangiocarcinoma AJCC v8 | Stage IV Hilar Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Pfizer

Not yet recruiting

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Melanoma and Skin Cancer Trials Limited

Not yet recruiting

Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma (NEOPECS)

Locally Advanced Cutaneous Squamous Cell Carcinoma
Acepodia Biotech, Inc.

Not yet recruiting

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
InSilico Medicine Hong Kong Limited

Not yet recruiting

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

Locally Advanced/Metastatic Solid Tumors
Jacobio Pharmaceuticals Co., Ltd.

Not yet recruiting

JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation

Advanced Non-squamous Non-small-cell Lung Cancer | Metastatic Non-squamous Non Small Cell Lung Cancer
AstraZeneca
Daiichi Sankyo

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung15)

Metastatic Non-small Cell Lung Cancer
Osel, Inc.
City of Hope Comprehensive Cancer Center; Miyarisan Pharmaceutical Co., Ltd.

Recruiting

Dose Finding Study of CBM588 in Combination With Nivolumab/Ipilimumab in Advanced Stage Renal Cell Carcinoma

Advanced or Metastatic Renal Cell Carcinoma

United States
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Phase II Study of SSGJ-707 Combination Therapy in Advanced NSCLC Patients

First-line Advanced NSCLC Patients

China
Tianjin Medical University Cancer Institute and...

Recruiting

Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure

HCC

China
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Chidamide Combined With Sintilimab and Bevacizumab for the First-line Treatment of Advanced Liver Cancer

Liver Cancer
University Hospital, Basel, Switzerland

Not yet recruiting

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors (ISCA-CHECK)

Advanced Solid Tumor

Switzerland
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine as Conversion Therapy of Locally Advanced Colorectal Cancer

Colorectal Cancer

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC

Pancreatic Adenocarcinoma | Advanced Cancer | Drug Use | Capecitabine | Oxaliplatin | First-Line | Cadonilimab | Nanoliposomal Irinotecan

China

Search clinical trials for: Advanced Glycation Endproduct Inhibitor

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