Search clinical trials for: Advanced or Refractory Solid Malignancies
Total 220743 results
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ModernaTX, Inc.RecruitingAdvanced Solid TumorsUnited States, United Kingdom, Australia, Spain
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RasCal Therapeutics, Inc.RecruitingGlioblastoma | Pancreatic Cancer | Lung Cancer | Colon Cancer | Advanced Malignant Solid Neoplasm | RAS MutationUnited States
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ModernaTX, Inc.AstraZenecaActive, not recruitingDose Escalation: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma | Dose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC LymphomaUnited States, Israel, Australia
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M.D. Anderson Cancer CenterMologen AGActive, not recruitingMelanoma | Advanced CancersUnited States
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Jounce Therapeutics, Inc.Completed
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingMalignant Solid Neoplasm | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate... and other conditionsUnited States
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OHSU Knight Cancer InstituteOregon Health and Science UniversityTerminatedPrimary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditionsUnited States
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Revolution Medicines, Inc.Active, not recruitingSolid TumorsUnited States
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AstraZenecaTerminatedLymphoma | Multiple Myeloma | Advanced Solid Tumors | Hematologic MalignanciesUnited States
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Cyteir Therapeutics, Inc.Active, not recruitingSoft Tissue Sarcoma | Follicular Lymphoma | Breast Cancer | Head and Neck Cancer | Small Cell Lung Cancer | Multiple Myeloma | Pancreatic Cancer | Ovarian Cancer | Mantle Cell Lymphoma | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | DLBCL | Non-hodgkin Lymphoma | Malignancy | CLLUnited States
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Revolution Medicines, Inc.SanofiCompletedSolid TumorUnited States, Korea, Republic of
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Prelude TherapeuticsCompletedAdenoid Cystic Carcinoma | Refractory Chronic Myelomonocytic Leukemia | Relapsed/Refractory Acute Myeloid Leukemia | Relapsed/Refractory Mantle Cell Lymphoma | Relapsed/Refractory Diffuse Large B-cell Lymphoma | Relapsed/Refractory Advanced Solid Tumors | Relapsed/Refractory Myelodysplasia | Relapsed...United States
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Revolution Medicines, Inc.SanofiActive, not recruitingSolid TumorsUnited States
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Alligator Bioscience ABCompletedNeoplasms | Solid TumorDenmark, Sweden
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ModernaTX, Inc.TerminatedOvarian Cancer | Relapsed/Refractory Solid Tumor Malignancies or LymphomaUnited States
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Nektar TherapeuticsTerminatedMelanoma | Sarcoma | Renal Cell Carcinoma | Colorectal Cancer | Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Merkel Cell CarcinomaUnited States
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Novita Pharmaceuticals, Inc.Translational Drug DevelopmentCompletedBreast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer | Pancreas Cancer | Liver Cancer | Ovary Cancer | Esophagus Cancer | Advanced or Metastatic Treatment-refractory Solid Tumor MalignanciesUnited States
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Incyte Biosciences International SàrlCompletedCervical Cancer | Hepatocellular Carcinoma | Esophageal Cancer | Ovarian Cancer | Mesothelioma | Non-small Cell Lung Cancer (NSCLC) | Urothelial Carcinoma | Merkel Cell Carcinoma | Diffuse Large B-cell Lymphoma | Triple-negative Breast Cancer | Renal Cell Carcinoma (RCC) | Small Cell Lung Cancer (SCLC) | Squamous... and other conditionsUnited States
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Massachusetts General HospitalCompletedLung Cancer | Solid Tumor (Not Breast or Prostate Cancers)United States
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EMD SeronoCompletedSolid TumorUnited States
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CelgeneCompletedCancer | LymphomasUnited States
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Janssen Research & Development, LLCCompletedNeoplasmsUnited States, Spain, Canada, Belgium
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Janssen Research & Development, LLCCompletedNeoplasms | Neoplasms, Breast | Neoplasms, Ovarian | Advanced or Refractory Solid MalignanciesUnited States, United Kingdom, Spain, Belgium
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University of Medicine and Dentistry of New JerseyNational Cancer Institute (NCI)Completed
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Merck Sharp & Dohme LLCAriad PharmaceuticalsCompletedLymphoma | Multiple Myeloma | TumorsUnited States
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Merck Sharp & Dohme LLCAriad PharmaceuticalsCompletedLymphoma | Multiple Myeloma | Tumors
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)WithdrawnLymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms
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Johnson & Johnson Pharmaceutical Research & Development...Janssen Pharmaceutica N.V., BelgiumCompletedPharmacokinetics | Advanced Malignancies | Solid Malignancies | Protein Kinase Inhibitors | Maximum Tolerated Dose | Antineoplastic Protocols | Clinical Trial, Phase 1
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Johnson & Johnson Pharmaceutical Research & Development...Completed
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Bristol-Myers SquibbCompletedHER2 or EGFR Expressing Advanced Solid MalignanciesSpain, France
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NovaceaUnknownNon-Hodgkin's Lymphoma | Solid MalignanciesUnited States
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Regeneron PharmaceuticalsNot yet recruitingMelanoma | Advanced Solid Tumors | Clear-Cell Renal-Cell Carcinoma (ccRCC)
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858 Therapeutics, Inc.RecruitingBreast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Advanced or Metastatic Solid Tumors | ER+ Breast Cancer | Castrate Resistant Prostate Cancer | BRCA MutationUnited States
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Zhejiang UniversityNot yet recruitingRenal Cell Carcinoma | Nasopharyngeal Carcinoma | Ovarian Cancer | Cervix Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Metastatic Tumor
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Genentech, Inc.RecruitingSolid Tumor, Adult | Refractory Cancer | Recurrent CancerAustralia
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OHSU Knight Cancer InstituteOregon Health and Science University; Incyte CorporationRecruitingAdvanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid NeoplasmUnited States
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23andMe, Inc.Recruiting
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Deciphera Pharmaceuticals LLCRecruitingMelanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene MutationUnited States
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GeneMedicine Co., Ltd.RecruitingRenal Cell Carcinoma | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Malignant MelanomaKorea, Republic of
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NiKang Therapeutics, Inc.RecruitingSmall Cell Lung Carcinoma | Gastric Cancer | Ovarian Neoplasms | Ovarian Cancer | Solid Tumor | Endometrial Neoplasms | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Endometrial Cancer | Small-cell Lung Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Solid... and other conditionsUnited States
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GigaGen, Inc.National Cancer Institute (NCI)RecruitingAdvanced or Metastatic Solid Tumor MalignanciesUnited States
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OnCusp Therapeutics, Inc.RecruitingOvarian Cancer | Solid TumorUnited States
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Alyssum TherapeuticsCBCC Global ResearchRecruiting
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Krystal Biotech, Inc.RecruitingMetastatic Renal Cell Carcinoma | Metastatic Colorectal Cancer | Lung Cancer Metastatic | Lung Cancer, Non-small Cell | Advanced Cancer | Solid Tumor, Adult | Metastatic Osteosarcoma | Metastatic Sarcoma | Metastatic Hepatocellular Carcinoma | Lung Cancer, Small CellUnited States
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Lantern Pharma Inc.RecruitingAdvanced Solid Tumor | Relapsed or Refractory LymphomasUnited States
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Dragonfly TherapeuticsRecruitingSolid Tumor, AdultUnited States, Australia, France
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ImmunoGenesisRecruitingSolid TumorUnited States
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Qurgen Inc.RecruitingBreast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Solid TumorUnited States
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Innolake BiopharmRecruitingMelanoma | Soft Tissue Sarcoma | Cervical Cancer | Head and Neck Cancer | Nasopharyngeal Carcinoma | Ovarian Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Classic Hodgkin LymphomaChina
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Flare Therapeutics Inc.RecruitingAdvanced Solid Tumors Cancer | Advanced Urothelial Carcinoma | Open Label | Oral Drug AdministrationUnited States