Search clinical trials for: Airflow Obstruction, Chronic

Total 31451 results

University of Birmingham
Salford Royal Foundation Trust

Recruiting

Sputum Colour Charts to Guide Antibiotic Self-treatment of Acute Exacerbation of COPD (Colour COPD)

Pulmonary Disease, Chronic Obstructive

United Kingdom
STS Medical

Not yet recruiting

Quantification of the Airflow Into Sinuses Before and After ArchSinus Implantation

Chronic Sinusitis, Ethmoidal
Gelb, Arthur F., M.D.

Recruiting

Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap

Emphysema | COPD, Emphysema, Asthma COPD Overlap

United States
Virginia Hawkins

Completed

Does Severity of Airflow Obstruction Correlate to Static Lung Volumes

Pulmonary Disease, Chronic Obstructive

United Kingdom
University of Nebraska
VA Nebraska Western Iowa Health Care System

Completed

Airway Macrophages and Sputum Milieu in Adult Subjects With Airflow Obstruction

Pulmonary Disease, Chronic Obstructive | Occupational Diseases | Tobacco Use Disorder | Bronchitis, Chronic

United States
Tufts Medical Center
Virginia Commonwealth University

Active, not recruiting

Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD Exacerbation | Airflow Obstruction

United States
CSA Medical, Inc.

Completed

Safety and Feasibility Study of Rejuvenair™ for Treating Chronic Bronchitis Patients (Feasibility)

Bronchitis, Chronic | Cryotherapy Effect

Netherlands, Canada, United Kingdom
Nuvaira, Inc.

Completed

Targeted Lung Denervation for Patients With Moderate to Severe COPD (AIRFLOW)

Chronic Obstructive Pulmonary Disease (COPD)

France, Belgium, Netherlands, Austria, Germany, United Kingdom
Mesoblast, Inc.

Completed

PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Chronic Bronchitis

United States
Imperial College London

Unknown

Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19 (PASSPORT)

COVID-19 | Asthma | Copd | Small Airways Disease

United Kingdom
Novartis Pharmaceuticals

Completed

A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251

Chronic Obstructive Pulmonary Disease, COPD

Poland, United States
Azienda Socio Sanitaria Territoriale degli Spedali...
Università degli Studi di Ferrara

Completed

Efficacy of Sub-gingival Air-polishing With Erythritol in the Treatment of Periodontitis (GBT2017)

Periodontitis, Aggressive | Periodontitis, Adult

Italy
University of Illinois at Chicago
National Heart, Lung, and Blood Institute (NHLBI)

Completed

COPD Assessment and Management Bundle Versus Usual Care

Chronic Obstructive Pulmonary Disease

United States
Forest Laboratories

Completed

Study To Assess Efficacy and Safety of Oglemilast in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States
Riphah International University

Completed

Icing and Airflow Stimulation in Obstructive Lung Diseases

Chronic Obstructive Pulmonary Disease

Pakistan
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstruction.

Respiratory Disorders

Sweden, United Kingdom
Queen's University

Completed

Effects of N-acetylcysteine on Cardiorespiratory Control in COPD Patients With Mild-to-moderate Airflow Obstruction

Pulmonary Disease, Chronic Obstructive
University of Cadiz
European Regional Development Fund

Completed

Feel Breathe, Restriction Device Ventilatory Nasal (COPD) (BreatheCOPD)

Chronic Obstructive Pulmonary Disease

Spain
Sunovion Respiratory Development Inc.

Completed

Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [ie, Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered With an Electronic eFlow Nebulizer System in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
Sunovion Respiratory Development Inc.

Completed

Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [i.e., Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered Using an eFlow Nebulizer in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
AstraZeneca

Completed

A Non-interventional Study to Investigate the Current Situation of Asthma-COPD Overlap Syndrome in Patients Over Age 40 With Persistent Airflow Limitation in China

Asthma-COPD Overlap Syndrome

China
GlaxoSmithKline

Completed

Investigation of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of Oral Danirixin in Symptomatic COPD Subjects With Mild to Moderate Airflow Limitation at Risk for Exacerbations

Pulmonary Disease, Chronic Obstructive

United States, Germany
AstraZeneca

Terminated

Comparison of Aclidinium Bromide and Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States
AstraZeneca

Completed

Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca

Completed

Efficacy, Safety and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, Formoterol Fumarate and Placebo for 28-Weeks Treatment in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Australia, Canada, New Zealand
Novartis Pharmaceuticals

Withdrawn

Safety and Efficacy of NVA237 as an add-on to Fixed Dose Combination LABA/ICS (GLOW8)

Chronic Obstructive Pulmonary Disease
AstraZeneca

Completed

Long-term Safety, Tolerability and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-35) (LAS-MD-35)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Efficacy, Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Aclidinium Bromide and Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Australia, Canada, New Zealand
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome

United States
AstraZeneca

Completed

Efficacy and Safety Study of Two Fixed-dose Combinations of Aclidinium Bromide With Formoterol Fumarate Compared With Aclidinium Bromide, Formoterol Fumarate and Placebo (LAC-MD-27)

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca

Completed

Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Invion, Inc.

Completed

Efficacy and Safety of Βeta-adrenoceptor Inverse Agonist and Biased Ligand, Nadolol, In Smoking Cessation of Patients With Chronic Cough With or Without Airflow Obstruction

Smoking Cessation

United States
AstraZeneca

Completed

Efficacy, Safety, and Tolerability of Aclidinium Bromide in the Treatment of Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-38) (LAS-MD-38)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Efficacy and Safety of Aclidinium Bromide for Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-33)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Long-term Extension Study of the Safety, Tolerability, and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-36)

Chronic Obstructive Pulmonary Disease

United States, Canada
Breathe Technologies, Inc.

Completed

Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) (PRIDE)

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease | Airflow Obstruction, Chronic

United States
Breathe Technologies, Inc.

Completed

In-home Evaluation of a Noninvasive Open Ventilation System in Patients With Severe Respiratory Insufficiency

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease | Airflow Obstruction, Chronic

United States
Novartis Pharmaceuticals

Completed

Comparison of Long-term Safety of the Combination Product QVA149A Against Placebo and Standard of Care Treatment in Chronic Obstructive Pulmonary Disease Patients With Moderate to Severe Airflow Limitation

Chronic Obstructive Pulmonary Disease (COPD)

Colombia, India, Korea, Republic of, Poland, Croatia, Estonia, Hungary, United Kingdom, Israel, Latvia, Turkey, Argentina, Panama, Mexico, Russian Federation, Serbia, Slovenia
Novartis Pharmaceuticals

Completed

A Multi-centre Randomized Double Blind 52-week Study to Assess the Safety of QVA149 Compared to QAB149 in Patients With COPD Who Have Moderate to Severe Airflow Limitation

Chronic Obstructive Pulmonary Disease (COPD)

United States, Romania, Hungary, Bulgaria, Spain, Finland, Puerto Rico
Novartis Pharmaceuticals

Completed

A 12 Week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation.

Chronic Obstructive Pulmonary Disease (COPD)

United States, Poland, Romania, Canada, Philippines, Spain, Ukraine, Vietnam
Novartis Pharmaceuticals

Completed

A 12-week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation

Chronic Obstructive Pulmonary Disease (COPD)

United States, Colombia, Egypt, Hungary, France, Guatemala, Panama, Slovakia, Slovenia
Arthur F Gelb MD

Completed

Evaluation Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange

COPD

United States
ROX Medical, Inc.

Completed

Study of the Effect of the ROX AC1 on Exercise Capacity and Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease

Germany
ROX Medical, Inc.

Completed

A Pilot Study to Evaluate the ROX Anastomotic Coupler System in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
GlaxoSmithKline

Completed

Airflow Limitation in Cardiac Diseases in Europe (ALICE)

Pulmonary Disease, Chronic Obstructive

Germany, Belgium, Spain, Ireland, Netherlands, Sweden, Italy, France, Greece
Paracelsus Medical University

Completed

SCOPE-Study: Salzburg Chronic Obstructive Pulmonary Disease- Exercise and Oxygen Study (SCOPE)

Chronic Obstructive Pulmonary Disease

Austria
The University of Hong Kong

Unknown

A Study on Smoking-related Lung Function Abnormalities and Correlation With Serum Biomarkers in Chinese

Chronic Airflow Obstruction

Hong Kong
Baqiyatallah Medical Sciences University

Completed

Can Airflow Limitation in Chronic Obstructive Pulmonary Disease (COPD) be Reversible by Drugs?

Chronic Obstructive Pulmonary Disease

Iran, Islamic Republic of
Deep Breeze

Completed

Vibration Response Imaging in Chronic Obstructive Pulmonary Disease and Asthma

Chronic Obstructive Pulmonary Disease | Asthma

United States
Hillel Yaffe Medical Center

Unknown

Correlation of Airflow Limitation and Other Respiratory Characteristics With Radiologic Changes of Lung Structure

Chronic Obstructive Pulmonary Disease

Israel

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