Search clinical trials for: Alpha Particle Therapy

Total 59867 results

Fusion Pharmaceuticals Inc.
AstraZeneca

Not yet recruiting

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Advanced Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Metastatic Colorectal Carcinoma

United States, Canada
Perspective Therapeutics

Recruiting

MC1R-targeted Alpha-particle Therapy Trial in Adults With Advanced Melanoma

Metastatic Melanoma | Melanoma (Skin) | Mucosal Melanoma | Melanoma Stage IV | Melanoma Stage III | Melanoma, Uveal

United States
Perspective Therapeutics

Recruiting

Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors (212-Pb-VMT)

Neuroendocrine Tumors | Pheochromocytoma | Carcinoid Tumor | Paraganglioma | Neuroendocrine Tumor of the Lung | Neuroendocrine Carcinoma Metastatic | Neuroendocrine Tumor of Pancreas | Neuroendocrine Tumor Carcinoid | Carcinoid Tumor of GI System

United States
Hekabio

Completed

Radiation Therapy (HB-001) by Alpha-particle Sources for Recurrent Malignant Solid Tumors in Japan

Breast Cancer | Head and Neck Cancer

Japan
Osaka University
Japan Agency for Medical Research and Development

Recruiting

Clinical Trial of Targeted Alpha Therapy for Prostate Cancer (Alpha-PS1)

Prostate Cancer

Japan
National Cancer Institute (NCI)

Not yet recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

Pheochromocytoma | Somatostatin Receptor Positive | Paragangliomas | Gastrointestinal Neuroendocrine Tumors

United States
Jules Bordet Institute
RayzeBio, Inc.

Not yet recruiting

A Phase I Study to Assess the Tolerability of 225Ac-DOTATATE in Patients With Refractory and Relapsing Multiple Myeloma Expressing Somatostatin Receptors (AcTRESS)

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory | Multiple Myeloma Progression

Belgium
Fusion Pharmaceuticals Inc.

Recruiting

FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) (AlphaBreak)

Metastatic Castration-resistant Prostate Cancer

United States
Gitte Fredberg Persson MD PhD

Recruiting

Longitudinal Study of Local Ablative Therapy in Oligometastatic Disease (OLIGO-DK)

Surgery | Oligometastatic Disease | Radiotherapy | Metastases | Stereotactic Radiation | Ablation Techniques

Denmark
Weill Medical College of Cornell University
The Leona M. and Harry B. Helmsley Charitable Trust

Not yet recruiting

Testing the Role for Anti-fungal Therapy in Improving the Response to Medicine for Crohn's Disease

Inflammatory Bowel Diseases | Crohn's Disease

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma | Estrogen Receptor-Positive Breast Carcinoma

United States
NorthShore University HealthSystem

Not yet recruiting

Effect of Tizanidine on Postoperative Urinary Retention After Sacrospinous Suspension

Postoperative Urinary Retention | Reconstructive Pelvic Surgery | Sacrospinous Vaginal Vault Suspension
Children's Oncology Group

Not yet recruiting

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Recurrent Juvenile Myelomonocytic Leukemia | Refractory Juvenile Myelomonocytic Leukemia
King's College Hospital NHS Trust
European Society of Intensive Care Medicine; Royal Centre for Defence Medicine

Not yet recruiting

The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock (REPERFUSE)

Septic Shock | Acute Kidney Injury

United Kingdom
University of California, Davis
United States Department of Defense

Recruiting

Molecularly Targeted Radionuclide Therapy Via the Integrin Alphavbeta6

Metastatic Nonsmall Cell Lung Cancer

United States
OncoCareClinic 308 Ltd

Recruiting

The 1st Tumor CytokinoTherapy Database (TCTD-1)

Oncology

Russian Federation
Chulalongkorn University
King Chulalongkorn Memorial Hospital

Recruiting

Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG (CMD03DIPG)

Diffuse Intrinsic Pontine Glioma | DIPG Brain Tumor

Thailand
Cairo University

Not yet recruiting

Low Level Diode Laser Versus Topical Chamomile in Management of Chemotherapy Induced Oral Mucositis

Chemotherapy Induced Oral Mucositis
CNAO National Center of Oncological Hadrontherapy

Recruiting

Sarcopenia in Head and Neck Cancer Patients Treated With Curative Hadrontherapy

Head and Neck Cancer

Italy
Jian Chen

Recruiting

Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Alpha Tau Medical LTD.

Recruiting

A Study of Diffusing Alpha Radiation Therapy for Patients With Breast Carcinoma in Frail or Elderly Patients.

Breast Cancer | Breast Carcinoma | Recurrent Breast Cancer

Israel
Medtronic - MITG
NAMSA

Not yet recruiting

Randomized Trial of UI-EWD vs. Conventional Endoscopic Therapy for Bleeding Ulcers (TREET)

Acute Gastrointestinal Bleeding
Hideho Okada, MD, PhD
National Cancer Institute (NCI); California Institute for Regenerative Medicine...

Recruiting

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

Glioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | MGMT-Unmethylated Glioblastoma

United States
General Hospital of Ningxia Medical University

Not yet recruiting

Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension on Maternal Hemodynamics

Outcome
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients

Adverse Effect
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment

Adverse Effect
General Hospital of Ningxia Medical University

Not yet recruiting

Intensive Versus Standard Treatment for Hypotension on Maternal Hemodynamics in Preeclamptic Patients

Adverse Effect
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment

Adverse Effect
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients

Adverse Effect
Mongolian National University of Medical Sciences
Mongolian National Cancer Center

Recruiting

Interferon Alpha Therapy for Cervical CINI and HPV Infection

HPV Infection | Cervical Dysplasia

Mongolia
McMaster University

Not yet recruiting

Nutritional Therapy in Late-onset Pompe Disease (PDT-MIS)

Obesity | Lysosomal Storage Diseases | Muscle Loss | Glycogen Storage Disease Type II | Pompe Disease | Nutrition Poor | Glycogen Storage Disease Type II, Adult | Glycogen Storage Disease Type II Late Onset
Maria Sklodowska-Curie National Research Institute...
Immutep S.A.S.

Recruiting

Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trial (EFTISARC-NEO)

Immunotherapy | Sarcoma,Soft Tissue | Radiation Therapy | Neoadjuvant

Poland
National Cancer Institute (NCI)

Not yet recruiting

A Study Comparing the Combination of Dasatinib and Chemotherapy Treatment With or Without Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or Philadelphia Chromosome-Like (Ph-Like) ABL-Class B-Cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
The 923rd Hospital of Joint Logistics Support Force...
Guangzhou Reforgene Medicine Co., Ltd.

Recruiting

Safety and Efficacy of RM-004 Cells for Hemoglobin H-Constant Spring Disease

Hemoglobinopathies | Hereditary Diseases | Alpha Thalassemia Hemoglobin H Constant Spring

China
Merck Sharp & Dohme LLC

Recruiting

A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

Essential Thrombocythemia

Poland, Israel, Australia, Hong Kong, Japan, New Zealand, Taiwan, Korea, Republic of, United States, Spain, Italy, Netherlands, Germany
Algemeen Ziekenhuis Maria Middelares

Recruiting

Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast Reconstruction (GDFT DIEP-flap)

Hypotension During Surgery

Belgium
Pfizer

Recruiting

A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2 (Tranquillo 2)

Stable Nonsegmental Vitiligo | Active Nonsegmental Vitiligo

China, Spain, Japan, Canada, United States, Hungary, Taiwan, Poland, Slovakia, Germany
Astellas Pharma Global Development, Inc.

Recruiting

A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats (OPTION-VMS)

Hot Flashes

United States
Federal University of Minas Gerais

Recruiting

Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome

Burning Mouth Syndrome

Brazil
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Recruiting

Spanish Decision Tool for Ovarian Cancer Maintenance Therapy

Ovarian Cancer

United States
Alpha Tau Medical LTD.

Not yet recruiting

Alpha Radiation Emitters Device for the Treatment of Pancreatic Cancer Emitters for the Treatment of Locally Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreatic Adenocarcinoma | Unresectable Pancreatic Cancer
Taichung Armed Forces General Hospital

Recruiting

Can Acupoint Low Intensity Shockwave Therapy Improve Bladder Voiding Efficiency

Detrusor Underactivity

Taiwan
Getz Pharma

Not yet recruiting

Medical Stone Expulsive Therapy for Acutely Obstructed Ureteric Calculi

Ureteric Stone of Lower Third of Ureter
Novartis Pharmaceuticals

Recruiting

A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.

Glioblastoma Multiforme | Gastroesophageal Adenocarcinoma | Pancreatic Ductal Adenocarcinoma

Netherlands, Spain, Israel, United States, Switzerland
Axsome Therapeutics, Inc.

Recruiting

A Study to Access the Efficacy and Safety of Solriamfetol in Subjects With ADHD (FOCUS)

ADHD

United States
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Interferon Alfa Therapy Based on Th17 Profile in Membranous Nephropathy (ALPHAGEM)

Membranous Nephropathy

France
Sarawak General Hospital
Universiti Sains Malaysia; Avantsar Sdn. Bhd.

Recruiting

Efficacy and Safety of Moisturising Cream With or Without Vitamin E and Urea Cream in Palmar-plantar Erythrodysesthesia (ECaPPE)

Palmar-Plantar Erythrodysesthesia | Palmar-Plantar Erythrodysesthesia Due to Cytotoxic Therapy

Malaysia
Odense University Hospital

Recruiting

Early Initiated Vasopressor Therapy in the Emergency Department (VASOSHOCK)

Shock | Shock, Septic | Hypotension | Hypovolemia | Hypotension and Shock | Hypovolemic Shock | Hypotension Symptomatic | Hypovolemic

Denmark
Fujun Zhang

Recruiting

Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma (RAFAS-001)

Sarcoma,Soft Tissue | Brachytherapy | Poly(ADP-ribose) Polymerase Inhibitors

China

Search clinical trials for: Alpha Particle Therapy

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