Search clinical trials for: Analytic treatment interruption

Total 63811 results

ANRS, Emerging Infectious Diseases

Recruiting

Assessment of HIV Remission Upon cART Interruption in Early Treated Individuals Carrying the MHC B35/53Bw4TTC2 Genotype

HIV Infections

France
National Cancer Institute (NCI)

Recruiting

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

HIV

United States
Boris Juelg, MD PhD
National Institute of Allergy and Infectious Diseases (NIAID); The University... and other collaborators

Recruiting

Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and VRC07-523LS in HIV-1-Infected Adults

Acquired Immunodeficiency Syndrome | Sexually Transmitted Diseases, Viral | Retroviridae Infections | HIV | Immunologic Deficiency Syndrome, Acquired

United States
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Clinical... and other collaborators

Recruiting

Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study

HIV Infection

Malawi, Botswana, South Africa, Zimbabwe
Steven Deeks
Caring Cross

Recruiting

CAR-T Cells for HIV Infection

HIV Infections

United States
University of California, San Francisco
Chan Zuckerberg Biohub

Recruiting

SCOPE Analytic Treatment Interruption Protocol (SCOPE-ATI)

HIV/AIDS

United States
National Institute of Allergy and Infectious Diseases...
ImmunityBio, Inc.; Rockefeller University

Recruiting

Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control During Analytic Treatment Interruption

HIV Infection

United States
SEARCH Research Foundation
US Military HIV Research Program

Recruiting

Post Analytic Treatment Interruption Study

HIV

Thailand
Mayo Clinic

Enrolling by invitation

Analytic Treatment Interruption (ATI) to Assess HIV Cure

HIV

United States
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Clinical... and other collaborators

Active, not recruiting

Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 704/HPTN 085 AMP Study

HIV Infection

United States, Peru, Brazil
AbbVie

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1

HIV Infection | HIV-1 | Human Immunodeficiency Virus (HIV)

United States, Australia, Canada, Puerto Rico
IrsiCaixa

Withdrawn

Immune Therapy and Analytical Treatment Interruption in HIV+ Participants Who Received an Allogeneic Stem Cell Transplantation (ITATI)

HIV Infection

Spain, Netherlands, Italy
International AIDS Vaccine Initiative
National Institute of Allergy and Infectious Diseases (NIAID); Beth Israel... and other collaborators

Completed

A Phase 1/2a Study of PGT121, VRC07-523LS and PGDM1400 Monoclonal Antibodies in HIV-uninfected and HIV-infected Adults

HIV/AIDS

United States
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Aelix Therapeutics

Completed

Study to Assess the Safety and Durability of Viral Control Beyond 24 Weeks of Analytical Treatment Interruption After the Administration of Candidate HIV-1 Vaccines DNA.HTI, MVA.HTI and ChAdOx1.HTI or Placebo in Early Treated HIV-1 Positive Individuals (ATI Extension of AELIX-002 Study)

HIV-1 Infection

Spain
Rockefeller University
National Institute of Allergy and Infectious Diseases (NIAID); Montefiore Medical... and other collaborators

Completed

3BNC117 and 10-1074 in ART-treated Individuals

Human Immunodeficiency Virus

United States
National Institute of Allergy and Infectious Diseases...

Completed

Vedolizumab (Anti-alpha4beta7) in Subjects With HIV Infection Undergoing Analytical Treatment Interruption

HIV

United States
National Institute of Allergy and Infectious Diseases...

Completed

Impact of a Short-Term Analytical Treatment Interruption and Re-Initiation of Antiretroviral Therapy on Immunologic and Virologic Parameters in HIV-Infected Individuals

HIV

United States
Institute of Tropical Medicine, Belgium
University Hospital, Ghent; Universitair Ziekenhuis Brussel; Agentschap voor... and other collaborators

Completed

Analytical Treatment Interruption in HIV Positive Patients (ISALA)

HIV-1 Infection

Belgium
Rockefeller University
University Hospital of Cologne

Completed

3BNC117 and 10-1074 in HIV-infected Individuals

Human Immunodeficiency Virus (HIV)

United States, Germany
University of Minnesota

Withdrawn

Predictors of Time to Viremia With an Analytic Treatment Interruption

HIV

United States
National Institute of Allergy and Infectious Diseases...

Completed

VRC-HIVMAB060-00-AB (VRC01) in People With Chronic HIV Infection Undergoing Analytical Treatment Interruption

HIV

United States
South East Asia Research Collaboration with Hawaii
National Institute of Allergy and Infectious Diseases (NIAID); National Institute... and other collaborators

Completed

Viral Suppression After Analytic Treatment Interruption in Thai Patients Who Initiated Highly Active Antiretroviral Therapy During Acute HIV Infection

Acute HIV Infection | Antiretroviral Treatment Interruption

Thailand
Argos Therapeutics

Completed

Safety and Efficacy Study of AGS-004 During Analytical Treatment Interruption

HIV Infection

United States, Canada
Nanjing First Hospital, Nanjing Medical University

Recruiting

Endostar Combined With SBRT and Envafolimab in the Treatment of Advanced Gastrointestinal Tumors

Gastrointestinal Neoplasms

China
UConn Health
National Institute of Mental Health (NIMH)

Recruiting

Personalized Depression Treatment Supported by Mobile Sensor Analytics (DepWatch)

Depression

United States
Williams College
Temple University

Recruiting

Using Technology to Investigate Lapses in a Weight Loss Program Among Individuals With Overweight and Obesity

Obesity | Weight Loss

United States
Sunnybrook Health Sciences Centre
GlaxoSmithKline

Recruiting

Alternative Dosing Of Niraparib To Decrease Dose Interruption In First Line Maintenance Treatment For Ovarian Cancer

Ovarian Cancer | Stage IV Ovarian Cancer | High Grade Ovarian Serous Adenocarcinoma | Stage III Ovarian Cancer

Canada
AstraZeneca
LOGEX Healthcare Analytics Amsterdam The Netherlands

Recruiting

Retrospective Study on Characteristics and Outcomes in Hospitalised Patients Treated With Ondexxya

Hemorrhage

Netherlands
Chinese PLA General Hospital

Recruiting

Thrombus Imaging and Treatment Analytics in Neurology (Titan)

Thrombosis | Thrombus, Brain

China
Hospital Clínico Universitario de Valladolid

Recruiting

Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption (MADRE-MIA)

Migraine | Headache, Migraine

Spain
University of California, San Francisco
Washington University School of Medicine; University of Washington; Pacific Pediatric... and other collaborators

Recruiting

Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma (PNOC027)

Medulloblastoma | Medulloblastoma, Childhood | Medulloblastoma Recurrent

United States
University of Greifswald
German Research Foundation; Charite University, Berlin, Germany; Hannover Medical... and other collaborators

Recruiting

A Comparison of Two Psychotherapy Programs in Persistently Depressed Treatment-Resistant Inpatients (ChangePDD)

Treatment-resistant Depression | Persistent Depressive Disorder

Germany
University Hospital, Antwerp
Universiteit Antwerpen

Recruiting

COIN-B: Controlled Interruption of Nucleos(t)Ide Analogue Treatment in Chronic Hepatitis B Infections (COIN-B)

Chronic Hepatitis B

Belgium
Sequenom, Inc.
Laboratory Corporation of America

Recruiting

The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis (RA)

United States
Albert Einstein College of Medicine

Completed

Percutaneous Interruption of the Coracohumeral Ligament for the Treatment of Frozen Shoulder (CHLTenex)

Adhesive Capsulitis

United States
IrsiCaixa
Hospital Clinic of Barcelona; University of Oxford; Germans Trias i Pujol Hospital and other collaborators

Completed

Study to Evaluate the Safety and Effect of HIVconsv Vaccines in Combination With Histone Deacetylase Inhibitor Romidepsin on the Viral Rebound Kinetic After Treatment Interruption in Early Treated HIV-1 Infected Individuals

HIV

Spain
ETOP IBCSG Partners Foundation
Alliance for Clinical Trials in Oncology; Canadian Cancer Trials Group; Breast...

Active, not recruiting

Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer (POSITIVE)

Early Breast Cancer

Korea, Republic of, United States, France, Canada, Spain, Lebanon, Belgium, Switzerland, Israel, Ireland, Japan, Italy, Denmark, Austria, Australia, Greece, Hungary, Netherlands, Norway, Portugal, Serbia, Slovenia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM) (A-DREAM)

Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Castration-Sensitive Prostate Carcinoma

United States
George Washington University
CareDx; VirginiaBio Analytics, LLC

Terminated

Personalization of Immunosuppressive Treatment for Organ Transplant Recipients (STAART)

Kidney Diseases | Kidney Failure, Chronic | Kidney Transplant Infection | Kidney Transplant Rejection | Kidney Injury | Kidney Disease, Chronic | Kidney Failure | Kidney Failure, Acute | Kidney Transplant; Complications | Kidney Ischemia

United States
Mucosa Innovations, S.L.

Completed

Oral Mucositis and Quality of Life With a Mucosa Topical Composition in Head & Neck Cancer Patients.

Quality of Life | Pain | Mucositis | Radiation Toxicity | Chemotherapeutic Toxicity | Oral Mucositis | Saliva | Speech

Spain
Centre Leon Berard

Completed

Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (ImadGist)

Gastrointestinal Stromal Tumors | Resected Gastrointestinal Stromal Tumors | Non-metastatic | High Risk of Recurrence | KIT Gene Mutation

France
Assistance Publique - Hôpitaux de Paris
Groupe Hospitalier Pitie-Salpetriere

Completed

Beta Blocker Interruption After Uncomplicated Myocardial Infarction (AβYSS)

Myocardial Infarction

France
COG Analytics
Friends Research Institute, Inc.

Completed

Continuing Care App for Probationers and Parolees

Substance Use Disorders

United States
The Canadian College of Naturopathic Medicine
Massachusetts General Hospital; McGill University; Mitacs; Ekhagastiftelsen; Netherlands... and other collaborators

Active, not recruiting

Dietary Counselling Plus Omega-3 Supplementation in the Treatment of Generalized Anxiety Disorder (EASe-GAD)

Generalized Anxiety Disorder

Canada
South East Asia Research Collaboration with Hawaii
The Thai Red Cross AIDS Research Centre; Cooper Human Systems

Completed

Efficacy of VHM After Treatment Interruption in Subjects Initiating ART During Acute HIV Infection

Acute HIV Infection

Thailand
Pfizer

Completed

A Study of a Potential Oral Treatment to Prevent COVID-19 in Adults Who Are Exposed to Household Member(s) With a Confirmed Symptomatic COVID-19 Infection

COVID-19

United States, Russian Federation, Thailand, Czechia, Colombia, Bulgaria, Japan, South Africa, Turkey, Argentina, Hungary, Malaysia, Mexico, Poland, Spain, Ukraine, Brazil
Servier

Completed

Non-drug Treatment Study in Parkinson's Disease Patients and Healthy Volunteers to Collect Biological Samples in Order to Assess ex Vivo the Activity of Candidate Therapies and Develop Novel Analytical Methods for Biomarkers (IRIS-CLE-LRRK2)

Parkinson Disease

France
American Gene Technologies International Inc.

Enrolling by invitation

An Antiretroviral Treatment Interruption (ATI) Study to Evaluate the Impact of Genetically Modified Autologous Cells (AGT103-T) to Suppress Human Immunodeficiency Virus Replication in the Absence of Antiretroviral Therapy

HIV

United States
R-Pharm International, LLC
Unimed Laboratories CJSC; Data Management 365; Center of Pharmaceutical Analytics...

Completed

Study to Evaluate the Efficacy and Safety of RPH-104 Treatment in Patients With Idiopathic Recurrent Pericarditis

Pericarditis

Russian Federation
Pfizer

Completed

To Examine the Effects of Axitinib Dose Reduction and Interruption for Adverse Event Management Among Patients Receiving Axitinib in for the Treatment of Advanced Renal Cell Carcinoma

Renal Cell Carcinoma

United States

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