Search clinical trials for: Anti TNF

Total 160197 results

Pfizer

Not yet recruiting

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Ascentage Pharma Group Inc.

Recruiting

A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.

CLL/SLL

China
Children's Hospital of Eastern Ontario

Not yet recruiting

PRecisiOn Microbiome Directed ExtensiOn of Anti-TNFα Crohn's Disease ThErapy in Children: The PROMOTE Trial (PROMOTE)

Inflammatory Bowel Diseases | Crohn Disease

Canada
Hellenic Institute for the Study of Sepsis

Recruiting

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) (REACT)

Community-acquired Pneumonia

Greece
Nemysis Ltd
RDC Clinical Pty Ltd

Recruiting

Safety and Effectiveness of Iron Hydroxide Adipate Tartrate (IHAT) in Iron Deficient Premenopausal Women

Iron-deficiency

Australia
Prof Curdin Conrad
Centre Hospitalier Universitaire Vaudois

Not yet recruiting

TYK2 Inhibition in Paradoxical Psoriasis (TYPP)

Psoriasis

Switzerland
Vastra Gotaland Region

Recruiting

Comparison Between Infliximab and Adalimumab on Patients With Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

Sweden
OncoCareClinic 308 Ltd

Recruiting

The 1st Tumor CytokinoTherapy Database (TCTD-1)

Oncology

Russian Federation
IMBiologics Corp.

Not yet recruiting

A Study of IMB-101 in Healthy Volunteers and Participants With Rheumatoid Arthritis

Rheumatoid Arthritis
The Third Xiangya Hospital of Central South University

Recruiting

IUS Combined With VAT Predicts Anti-TNF-α Efficacy in Patients With IBD: a Prospective Study

Inflammatory Bowel Diseases | Predictors | Intestinal Ultrasound | Visceral Adipose Tissue | TNF-α

China
Merck Sharp & Dohme LLC

Recruiting

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States, Israel, Taiwan, United Kingdom, Chile, Canada, Japan, Brazil, China
NorthShore University HealthSystem
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Effects of TNF Blockade on Human BPH/LUTS

Benign Prostatic Hyperplasia (BPH)

United States
Tom Appleton
Western University; Canadian Research Group in Immuno-Oncology

Not yet recruiting

Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

Inflammatory Arthritis | Immune-related Adverse Event
Duke University
International Headache Society

Recruiting

NDPH Biomarker Study in Children and Adolescents

New Persistent Daily Headache

United States
Hospital del Río Hortega
Francisco Javier Garcia Alonso; Jesús Barrio

Recruiting

Influence of HLA-DQA1*05 Genotype in Adults With Anti-TNF Treatment With Proactive Therapeutic Drug Monitoring. (Proa-DQ)

Inflammatory Bowel Diseases | Drug Monitoring

Spain
Federico II University
Crohn's and Colitis Foundation

Not yet recruiting

AppenDectomy Vs ANti TNF-a in Inducing Clinical and EnDoscopic Remission in Left-sided Ulcerative Colitis (ADVANCED-UC)

Ulcerative Colitis
Assistance Publique - Hôpitaux de Paris

Recruiting

Certolizumab in Recurrent Implantation Failure (RIF) (CERTIFY)

Recurrent Unexplained Implantation Failure

France
University of Calgary
Alimentiv Inc.

Recruiting

PATHFINDER: Evaluating the Optimal First-Line Treatment Strategy for Moderate-to-Severely Active Ileal-dominant Crohn's Disease

Crohn Disease

Canada
Lihua Duan

Not yet recruiting

Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ Fusion Protein in the Treatment of Acute Gout

Acute Gout

China
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy (Step-Up HS)

Hidradenitis Suppurativa

United States, Japan, Australia, Canada, Korea, Republic of, New Zealand, Puerto Rico, Spain, Austria, Italy, Bulgaria, Israel, Taiwan, Croatia, Hungary, Netherlands, Switzerland, Germany, Portugal, France, United Kingdom, Czechia, ... and more
Institut Claudius Regaud
Institut National de la Santé Et de la Recherche Médicale, France

Recruiting

Blocking TNF to Potentiate the ICI-dependent Immune Awakening in Melanoma (ATPIC)

Melanoma | Immune Defect | Tumor Skin

France
Jagiellonian University

Recruiting

Subclinical Hypothyroidism and Chronic Inflammation in PCOS

Subclinical hypothyroïdism | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries | Hypothalamic-Pituitary-Gonadal Axis Dysfunction

Poland
AbbVie

Recruiting

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis (SELECT- SWITCH)

Rheumatoid Arthritis

United States, Japan, United Kingdom, Canada, Korea, Republic of, Puerto Rico, South Africa, Hungary, Bulgaria, Spain, Portugal, Chile, Croatia, France, Belgium, Germany, Greece, Romania, Brazil, Italy, Serbia, China, Colombia, Mexico
University Hospital, Montpellier

Recruiting

Study of the Functional Status Neutrophils in Rheumatoid Arthritis Patients to Identify New Biomarkers of Response to Anti-TNFalpha Therapy (NeutroARTherap)

Rheumatoid Arthritis

France
Connecticut Children's Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Emory... and other collaborators

Recruiting

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease (CAMEO)

Crohn Disease

United States, Canada
Insel Gruppe AG, University Hospital Bern
Bristol-Myers Squibb

Recruiting

Combined Microbiota and Metabolic Signature in Ulcerative Colitis Predicts Anti-Inflammatory Therapy Success (COMMIT)

Ulcerative Colitis

Switzerland
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of TNF-alpha Antagonists (Infliximab) Withdrawal in Sarcoidosis (TAWIS)

Sarcoidosis

France
University of Pennsylvania
Janssen Scientific Affairs, LLC

Recruiting

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients (EVOLUTION)

Psoriatic Arthritis

United States
University of Pennsylvania
Janssen Scientific Affairs, LLC

Not yet recruiting

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients (EVOLUTION)

Psoriatic Arthritis

United States
Qilu Hospital of Shandong University

Recruiting

The Clinical Efficacy of Immunomodulators in RA Patients

Arthritis, Rheumatoid

China
Rambam Health Care Campus

Recruiting

Pre-treatment With Azithromycin to Reduce Immunogenicity to to Anti-TNF Agents in Patients With Crohn's Disease (AZITRATIM)

Biological Substance; Adverse Effect | Crohn's Disease Relapse

Israel
ANRS, Emerging Infectious Diseases

Recruiting

Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis (TIMPANI)

Tuberculous Meningitis | HIV I Infection

Mozambique, Brazil, Zambia
Jiangsu Simcere Pharmaceutical Co., Ltd.

Recruiting

A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma

Advanced Solid Tumor | Cutaneous T-cell Lymphoma (CTCL)

United States
Sohag University

Not yet recruiting

Comparative Study of Janus Kinase (JAK) Inhibitors Vs Tumor Necrosis Factor (TNF) Inhibitors in Rheumatoid Arthritis

Rheumatoid Arthritis
University Hospital, Clermont-Ferrand
University of Southampton; Institut National de Recherche pour l'Agriculture...

Not yet recruiting

The Oxylipin Response as a New PrEdictive Biomarker of Patient Responsiveness to Biotherapy in Rheumatoid Arthritis (OPERA) (OPERA)

Rheumatoid Arthritis

France
Sun Yat-sen University
Shanghai Weike Bioscience Co., Ltd.

Not yet recruiting

A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC

Nasopharyngeal Carcinoma | TNF | Chemo-radiotherapy
University Hospital, Montpellier

Recruiting

Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis (SEQUENS-RA)

Rheumatoid Arthritis

France, Monaco
University of Sulaimani

Recruiting

Therapeutic Response to Tumor Necrosis Factor-alpha (TNF-alpha) Antagonists in Rheumatoid Arthritis. (TNF-alpha)

Rheumatoid Arthritis | Inflammatory Arthritis | Ankylosing Spondylitis

Iraq
University of Pisa

Recruiting

Infliximab Efficacy, TDM and Serum TNFα Levels in Pediatric HSCT Recipients With aGVHD: Prospective Observational Study

Hematopoietic Stem Cell Transplantation | Graft Versus Host Disease, Acute

Italy
Fundación de Investigación Biomédica - Hospital...

Recruiting

Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events

Ulcerative Colitis | Thromboembolism

Spain
Marie Hudson, MD
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Recruiting

Stand UP to Rheumatoid Arthritis (SUPRA) (SUPRA)

Rheumatoid Arthritis

Canada
TILT Biotherapeutics Ltd.
Merck Sharp & Dohme LLC

Recruiting

Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab and Pegylated Liposomal Doxorubicin as Treatment for Ovarian Cancer. (PROTA)

Platinum-resistant Ovarian Cancer | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Refractory Fallopian Tube Carcinoma | Platinum-Refractory Primary Peritoneal Carcinoma | Platinum-refractory Ovarian Carcinoma | Platinum-Sensitive Ovarian... and other conditions

United States, Finland
Navidea Biopharmaceuticals

Recruiting

Tc 99m Tilmanocept Imaging for Early Prediction of Anti-TNFα Therapy Response in Moderate to Severe Active RA

Rheumatoid Arthritis

United States
Centre Hospitalier Universitaire de Besancon

Recruiting

Biomedicines and Bacterial Translocation in Spondyloarthritis (TEARE-BIO)

Axial Spondyloarthritis

France
TILT Biotherapeutics Ltd.

Recruiting

Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1 (AVENTIL)

Melanoma | Head and Neck Squamous Cell Carcinoma

United States, Finland
Hanyang University Seoul Hospital
Linical Korea

Not yet recruiting

REduCed Dose of TNFi in Patients With Ankylosing SpondyliTis (RECAST)

Ankylosing Spondylitis | Axial Spondyloarthritis
Dan Liang

Recruiting

Reduction or Discontinuation of TNF-α Inhibitor in Non-infectious Uveitis Patients

Uveitis | Adalimumab

China
Ottawa Hospital Research Institute
The Ottawa Hospital; University of Ottawa

Not yet recruiting

Early Changes in Pain, Disease Activity, and Ultrasound Evidence of Inflammatory Synovitis in Patients Receiving JAK-inhibitor vs. TNF-inhibitor Therapy for Active Rheumatoid Arthritis: A Feasibility Study.

Rheumatoid Arthritis
AbbVie

Recruiting

A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy

Hidradenitis Suppurativa

United States, Australia, Canada, Germany, Greece, Japan, Spain, Puerto Rico
Jeffrey Curtis
Bristol-Myers Squibb; Eli Lilly and Company; University of Pennsylvania; Novartis; Pfiz... and other collaborators

Recruiting

COVID-19 VaccinE Response in Rheumatology Patients (COVER)

Rheumatoid Arthritis | Spondylarthritis | Psoriatic Arthritis

United States

Search clinical trials for: Anti TNF

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