Search clinical trials for: Antibody and Cell-mediated Immune Responses

Total 474429 results

Radboud University Medical Center
Pfizer; ImaginAb, Inc.; University Hospital Tuebingen

Not yet recruiting

Immuno-pet iMaging resPonses administeRed Immune checkpoiNt inhibiTor (IMPRINT)

NSCLC

Germany, Netherlands
Aditxt, Inc.

Recruiting

Immune Responses to COVID-19 Infection or Vaccination

COVID-19

United States
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

COVID-19 Vaccine Responses in PIDD Subjects

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Primary Immune Deficiency | Primary Antibody Deficiencies | CVID | XLA | Secondary Hypogammaglobulinemia

United States
INanoBio Inc.
TMC HealthCare

Recruiting

Investigation of Antibody and Immune Responses to SARS-CoV-2 Proteins in COVID-19 Patients (SARS-CoV-2)

COVID-19 | SARS-CoV-2 Infection

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

A Longitudinal Study of COVID-19 Sequelae and Immunity

COVID-19

United States
VBI Vaccines Inc.

Completed

Safety, Tolerability, and Immunogenicity of the COVID-19 Vaccine Candidates VBI-2902a and VBI-2905a

Covid19

Canada
OHSU Knight Cancer Institute
Oregon Health and Science University

Terminated

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Primary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditions

United States
Viela Bio (acquired by Horizon Therapeutics)

Completed

A Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Prophylaxis of Allograft Rejection in Adults Receiving a Kidney Transplant

Kidney Transplantation | Transplant Rejection | Allografts | Rejection; Transplant, Kidney

United States
Chinese University of Hong Kong

Enrolling by invitation

COVID-19 Serology in People Living With HIV in Hong Kong

HIV Infections | SARS-CoV-2 Infection | Vaccination; Infection

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Amsterdam UMC Clinical Trial With a Native-like HIV-1 Envelope Vaccine (ACTHIVE-001)

HIV-1-infection

Netherlands
Association "Naso Sano" Onlus

Enrolling by invitation

Clinical and Immunological Responses After SARS-CoV-2 Infection Causing COVID-19

COVID-19 | Covid19 | SARS-CoV2 Infection | Olfactory Disorder | Smell Disorder | Smell Loss

Italy
Chulalongkorn University
National Vaccine Institute, Thailand; Chula Vaccine Research Center (ChulaVRC)... and other collaborators

Completed

ChulaCov19 Vaccine in Healthy Adults

COVID-19 Vaccine | Safety Issues

Thailand
Imperial College London

Active, not recruiting

Modelling the Interaction Between Rationally-designed Synthetic Model Viral Protein Immunogens (EAVI2020_01)

HIV-1-infection

United Kingdom
Ogevity Therapeutics, Inc.
National University, Singapore

Completed

Immune Responses With Reduxium

Viral Infection | Immune Tolerance

Singapore
Imperial College Healthcare NHS Trust

Completed

Nasal and Systemic Immune Responses to Nasal Influenza Vaccine (Flu-M3)

Influenza | Vaccine Virus Shedding

United Kingdom
Dragonfly Research, LLC

Completed

Humoral and T-Cell Responses to COVID-19 Vaccination in Multiple Sclerosis Patients Treated With Ocrelizumab Treated With Ocrelizumab or Natalizumab (OCR-VAX)

Pathologic Processes | Nervous System Diseases | Immune System Diseases | Multiple Sclerosis | Demyelinating Autoimmune Diseases, CNS | Autoimmune Diseases of the Nervous System | Demyelinating Diseases | Autoimmune Diseases

United States
Imperial College London
Bill and Melinda Gates Foundation

Completed

Optimising DNA Vaccinations in Healthy Volunteers (DNAVAC001)

HIV-1-infection
National Institute of Allergy and Infectious Diseases...

Completed

Challenge Infection of Healthy Adult Volunteers With RSV A2

Upper Respiratory Tract Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-EBOMAB092-00-AB (MAb114), Administered Intravenously to Healthy Adults

Healthy Adult Immune Responses to Vaccine

United States
MCM Vaccines B.V.
Merck Sharp & Dohme LLC; Sanofi Pasteur, a Sanofi Company

Completed

Long-term Persistence of Hepatitis B and Pertussis Antibody Responses in Healthy 4 to 5 Year Old Children Previously Vaccinated With Vaxelis® or INFANRIX® Hexa (V419-012)

Hepatitis B | Pertussis
Public Health England
Institute of Child Health; National Institute of Biological Standards and Control

Completed

Study to Evaluate the Immune Response of United Kingdom (UK) Infants Receiving DTaP/Hib/IPV, Meningococcal C Conjugate and Pneumococcal Conjugate Vaccines, Antibody Persistence and Responses to Booster Doses in the Second Year of Life (Sched2)

Pneumococcal Infections | Meningococcal Infections

United Kingdom
University of Virginia
National Cancer Institute (NCI)

Unknown

Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma

Recurrent Neuroblastoma | Disseminated Neuroblastoma

United States
National Eye Institute (NEI)

Completed

Immune Responses to Antigens in Non-infectious Eye Inflammatory Diseases

Eye Diseases

United States
GlaxoSmithKline

Withdrawn

A Study to Evaluate the One Year Long-term Persistence of Immune Responses Following Two Different Rabies Vaccine Post-exposure Regimens in Chinese Children

Virus Diseases
GlaxoSmithKline

Completed

A Study to Evaluate Persistence of Immune Responses After Post-exposure Prophylaxis of Rabipur® (Purified Chicken-embryo Cell Rabies Vaccine) in Chinese Children

Virus Diseases

China
Imperial College London
Medical Research Council; Wellcome Trust

Completed

Investigating Immunisation Strategies of DNA, MVA and CN54rgp140 Adjuvanted With GLA-AF to Maximise Antibody Responses (UKHVCSpoke003)

HIV

United Kingdom
Vanderbilt University
Centers for Disease Control and Prevention; Marshfield Clinic Research Foundation

Completed

Factors Associated With Maintenance of Antibody Responses to Influenza Vaccine in Older, Community-Dwelling Adults

Aging
National Institute of Allergy and Infectious Diseases...
The Emmes Company, LLC

Completed

Evaluation of Influenza-Specific Immune Responses in Children and Adults During the 2010-2011 Influenza Season in the U.S.

Influenza

United States
Papua New Guinea Institute of Medical Research
The University of Western Australia

Completed

Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea

Pneumonia | Meningitis | Otitis Media

Papua New Guinea
French National Agency for Research on AIDS and...
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Antibody Responses to Pneumococcal Vaccines Among HIV-Infected Adults.

HIV Infections
Anastasia Vishnevetsky, MD, MPH
argenx

Not yet recruiting

Efgartigimod for the Treatment of Acute Optic Neuritis (PET-AON)

Optic Neuritis

United States
Fujian Cancer Hospital
Zhangzhou Municipal Hospital of Fujian Province

Recruiting

Nituzumab Plus Serplulimab Combined With SBRT in Cervical Cancer

Cervical Cancer

China
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Refractory Grade 1 Follicular Lymphoma | Refractory Grade 2 Follicular Lymphoma | Refractory Grade 3a Follicular Lymphoma

United States
Zumutor Biologics Inc.

Recruiting

Phase 1 Trial of ZM008 as Single Agent and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Colorectal Cancer | Esophageal Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Pancreas Adenocarcinoma | Diffuse Large B Cell Lymphoma | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Biliary Tract Cancer | High Grade Ovarian Serous Adenocarcinoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States
Xuanwu Hospital, Beijing

Recruiting

National, Multicentric Registry Study on Neuroimmunological Diseases in China (NIDBase)

Multiple Sclerosis | Myasthenia Gravis | Autoimmune Encephalitis | Acute Disseminated Encephalomyelitis | NMO Spectrum Disorder | Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

China
Xijing Hospital

Recruiting

Preoperative Adjuvant SOX Plus PL-1 Antibody and FLOT Plus PD-1 Antibody for Locally Advanced dMMR Gastric Cancer

Gastric Cancer | Chemotherapeutic Toxicity | Immune-related Adverse Event

China
University of Washington

Not yet recruiting

Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphoma

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma | Ann Arbor Stage II Marginal Zone Lymphoma | Ann Arbor Stage III Marginal Zone Lymphoma and other conditions

United States
Ruijin Hospital

Not yet recruiting

Efficacy of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL

Diffuse Large B-Cell Lymphoma
M.D. Anderson Cancer Center
Incyte Corporation

Not yet recruiting

Phase II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion

Advanced Cholangiocarcinoma | FGFR2 Fusion

United States
MedMira Laboratories Inc.

Not yet recruiting

Cross-sectional Investigational Study to Evaluate the Sensitivity, Specificity, and Utility of the MedMira Inc. Multiplo® Complete Syphilis (TP/nTP) Antibody Test (POCT) to Diagnose Infectious Syphilis in Participants Attending the Sexual Health Clinic in Ottawa, Ontario.

Treponema Pallidum

Canada
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study and Modulation of Immune Responses in Primary and Metastatic Colon Cancers (I-COMET)

Colon Cancer | Peritoneal Carcinoma

France
Rallybio IPA, LLC

Not yet recruiting

Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

Fetal and Neonatal Alloimmune Thrombocytopenia
Michael Hoelscher
Jimma University; St. Paul's Hospital Millennium Medical College, Ethiopia

Recruiting

SARS-CoV-2 Specific Antibody Responses and Impact for COVID-19 Disease in Ethiopia (CoVICIS)

COVID-19 Recurrent | SARS CoV 2 Infection | COVID-19 Breakthrough

Ethiopia
First Affiliated Hospital of Wenzhou Medical University
Shanghai First Song Therapeutics Co., Ltd

Not yet recruiting

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Fruquintinib and Albumin-paclitaxel Combined With or Without PD-1 Antibody in 2nd-line Treatment of G/GEJ Adenocarcinoma

Gastric Cancer
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
Osel, Inc.
National Cancer Institute (NCI); City of Hope Medical Center; Miyarisan Pharmaceuticals...

Recruiting

CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

Metastatic Renal Cell Carcinoma | Metastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Sarcomatoid Renal Cell Carcinoma | Advanced Renal Cell Carcinoma | Advanced Sarcomatoid Renal...

United States
Médecins du Monde
University of Bristol; PATH; UNITAID; Burnet Institute; Population Services International and other collaborators

Not yet recruiting

Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income Countries

Hepatitis | Hiv | Drug Use
Chinese PLA General Hospital

Recruiting

Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.

PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma

China

Search clinical trials for: Antibody and Cell-mediated Immune Responses

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