Search clinical trials for: Apolipoprotein B-100, Familial Defective

Total 26915 results

Click Therapeutics, Inc.

Active, not recruiting

An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis

Psoriasis | Atopic Dermatitis

United States
Click Therapeutics, Inc.

Completed

An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer

Multiple Sclerosis | Breast Cancer | Lung Cancer

United States
University Hospital, Bonn

Completed

Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretion (SVS)

Hypercholesterolemia

Germany
Astellas Pharma Inc
Toray Industries, Inc

Completed

Study to Compare Pharmacokinetic Profiles of TRK-100STP in Japanese, Chinese, and South Korean Non-elderly Healthy Adult Males

Healthy Adult Male | Pharmacokinetics of TRK-100-STP

Japan
Novo Nordisk A/S

Completed

A Research Study of How a New Medicine NNC0365-3769 (Mim8) Works in the Body of Healthy People

Healthy Volunteers - Haemophilia A

Germany
Göteborg University
Sahlgrenska University Hospital, Sweden

Completed

Effect of Body Weight Loading on Urinary Electrolyte Excretion (EBU)

Obesity | Edema

Sweden
Chong Kun Dang Pharmaceutical

Unknown

Clinical Trial to Investigate the Pharmacokinetics and Safety of CKD-393

T2DM (Type 2 Diabetes Mellitus)

Korea, Republic of
National Taiwan University Hospital

Recruiting

Ropeginterferon Alfa 2b for Early MyelofibrosisDIPSS Low/Intermediate-1 Risk Myelofibrosis

Pre-fibrotic Myelofibrosis

Taiwan
National Taiwan University Hospital

Recruiting

Clinical Decision-Making and Virtual Reality Exercise

Degenerative Disc Disease | Degenerative Spondylolisthesis | Degenerative Intervertebral Discs | Degenerative Lumbar Spinal Stenosis

Taiwan
Medinox, Inc.
Orient Europharma Co., Ltd.

Completed

NOX-100 for Preventing Hypotension During Hemodialysis

Hypotension

Taiwan
Istinye University

Completed

Pectoralis Minor Shorthening and Swimming Performance

The Study Will Not be Based on Any Disease | Ability to Swim 100m Independent Freestyle | Be Between the Ages of 9-16 | Continuing Running as Part of a Sports Club

Turkey
Massachusetts General Hospital
Fisher Wallace Labs, LLC

Completed

Efficacy and Safety of Cranial Electrical Stimulation (CES) for Major Depressive Disorder (MDD)

Major Depressive Disorder

United States
Heron Therapeutics

Active, not recruiting

Safety Study of Repeat Doses of SUSTOL in Adults

Chemotherapy-Induced Nausea and Vomiting (CINV)

United States
Bharat Biotech International Limited

Completed

A Trial Using Double-Bolus THR-100 Versus Streptokinase (THR-100)

Acute Myocardial Infarction

India
National Taiwan University Hospital

Active, not recruiting

Analysis of Risk Factors and Prognosis of Pediatric Patients After Operations for Congenital Heart Disease

Congenital Heart Disease | Pediatric

Taiwan
Nemours Children's Clinic

Completed

Metabolism of Fibrinogen and Apolipoprotein B-100 in Childhood Obesity and Cardiovascular Disease

Obesity | Cardiovascular Disease
Azienda Ospedaliero-Universitaria Consorziale Policlinico...
Prof. Carlo Manno; Dott. Francesco Pesce; Dott. Michele Rossini; Dott. Vincenzo...

Unknown

Correlation Between Platelet Function Analyzer-100 Testing and Bleeding Events After Percutaneous Kidney Biopsy

Kidney Diseases | Hemorrhage | Blood Platelet Disorder

Italy
Pusan National University Hospital
Pusan National University Yangsan Hospital

Unknown

Nasogastric Tube Insertion Using Cook Airway Exchange Catheter in Anesthetized Patients

Elective Surgery of Gastrointestinal Tract | 100 Adults Aged Between 20 and 70 Years Old | ASA Physical Status of I or II

Korea, Republic of
Thai Red Cross AIDS Research Centre
Johns Hopkins University; Centers for Disease Control and Prevention; The HIV...

Completed

Behavioral and Biomedical HIV Prevention Interventions for Thai Men Who Have Sex With Men (HIV-NAT 120)

HIV Testing, MSM

Thailand
Novartis
Novartis Vaccines

Completed

A Study to Evaluate Safety and Immunogenicity of Trivalent Influenza Vaccine, Formulation 2015 Southern Hemisphere, When Administered to Healthy Adult Subjects.

Human Influenza

Brazil
U.S. Army Medical Research and Development Command
National Institute of Allergy and Infectious Diseases (NIAID); US Military... and other collaborators

Recruiting

Safety, Tolerability, and Immunogenicity of ALFQ in a HIV Vaccine Containing A244 and B.65321 in Healthy Adults (RV575)

Human Immunodeficiency Virus (HIV) | AIDS Virus

United States
University of Malaya
Pfizer; Cancer Research Malaysia; Pantai Hospital Kuala Lumpur; Hospital Sultan...

Recruiting

Efficacy of Talazoparib in Asian Metastatic Breast Cancer Patients With a Homologous Recombinant Deficiency (HRD) Signature

Triple Negative Breast Cancer | HRD 100 Gene Expression High

Malaysia
Chong Kun Dang Pharmaceutical

Completed

Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-393 in Healthy Subjects

Diabetes Mellitus, Type 2

Korea, Republic of
University of Mississippi Medical Center

Terminated

Does An Abnormal PFA 100 Predict Bleeding After Renal Biopsy?

Hemorrhage | Kidney Failure, Chronic | Blood Platelet Disorders | Kidney Failure, Acute

United States
National Medical Research Center for Therapy and...
Moscow State University of Medicine and Dentistry

Recruiting

Genetic Testing and Motivational Counseling for FH (GENMOTIV-FH)

Medication Adherence | Adherence, Medication | Treatment Adherence | Familial Hypercholesterolemia | Motivational Interviewing | Adherence, Patient | Treatment Adherence and Compliance | Patient Compliance | Adherence | Hypercholesterolemia, Familial | Patient Adherence | Hypercholesterolemia, Autosomal Dominant and other conditions

Russian Federation
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Male Subjects

Cardiovascular Disease | Healthy Male Subjects

United Kingdom
GlaxoSmithKline

Terminated

A First Time in Human Study Exploring Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2618960 in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis (RRMS)

Multiple Sclerosis, Relapsing-Remitting

United Kingdom
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol Levels

Hypercholesterolemia

Germany
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study in Subjects on Stable Statin Therapy

Hypercholesterolemia

Netherlands, United States
Chong Kun Dang Pharmaceutical

Completed

Study to Assess PK/PD Character, Safety/Tolerability of CKD-519 New Formulation in Healthy Male Subject.

Dyslipidemia

Korea, Republic of
Aalborg University Hospital
Aarhus University Hospital

Completed

Assessment of Serum Cystatin C as a Marker of Kidney Function in Children

Kidney Disease

Denmark
La Jolla Pharmaceutical Company

Completed

Study of the Safety of GCS-100 in Subjects With Chronic Lymphocytic Leukemia (PR-CS008)

Chronic Lymphocytic Leukemia

United States
Ranbaxy Laboratories Limited

Completed

A Comparitive Bioavailability Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fasting Conditions and After Low and High Fat Meal

Healthy
Bayer

Completed

Continuous Dosing of BAY73-4506 in Patients With Advanced Malignancies

Neoplasm

United States
University of Florida
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Effects of Deep Brain Stimulation on Motor, Mood, and Cognitive Symptoms in Parkinson's Disease

Parkinson Disease

United States
La Jolla Pharmaceutical Company

Withdrawn

GCS-100LE in Combination With Etoposide and Dexamethasone in Relapsed or Refractory Diffuse Large B-Cell Lymphoma (GCS-100LE)

Diffuse Large B-cell Lymphoma

United States
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Evaluate the Effectiveness of First Aid E-book Intervention Among New Nurses

First Aid | Knowledge | Self-efficacy

Taiwan
OrthoTrophix, Inc

Completed

A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees

Knee Osteoarthritis

United States
University of California, Los Angeles

Completed

NOrth American Study for the Treatment of Recurrent epIstaxis With DoxycycLine: The NOSTRIL Trial (NOSTRIL)

Epistaxis

United States
Agios Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Mitapivat (AG-348) in Healthy Adult Participants

Healthy Volunteers

United States
Wageningen University
Friesland Campina

Unknown

Postprandial Effects of Milk Fats (POEMI)

Nutrition | Metabolism | Genomics | Postprandial Metabolism

Netherlands
Horizon Pharma Ireland, Ltd., Dublin Ireland
Ucyclyd Pharma, Inc.

Completed

A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group

Hepatic Encephalopathy | Urea Cycle Disorders

Ukraine
Mespere Lifesciences Inc.

Unknown

ED Decision Making Among Hypotensive Patients

Hypotension

United States
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Completed

Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia

Presbyopia

China
Novartis Vaccines

Completed

Safety and Dose Ranging Study of Acellular Pertussis and Acellular Pertussis -Tetanus-Diphtheria Booster Vaccines in Healthy Adults Ages 18 to 40 Years

Pertussis | Whooping Cough | Tetanus | Diphtheria | Lockjaw

Belgium
Medical University of Vienna

Recruiting

The Effect of Hyperoxia and Hypoxia on Fluorescence Lifetime Imaging Ophthalmoscopy in Healthy Subjects- a Randomized, Double Blind, Crossover Study

To Investigate the Effect of 100% Oxygen Breathing on Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Healthy Subjects

Austria
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Osaka University
Merck Sharp & Dohme LLC

Unknown

Relationship Between CETP Deficiency and Atherosclerosis in Patients With Hyperalphalipoproteinemia (INFINITY)

Hyper-LDL-cholesterolemia | Low CETP Activity | CETP Deficiency | Hyperalphalipoproteinemia | High Level of Remnant Cholesterol

Japan
San Diego State University

Completed

AVACEN Treatment Method and Postprandial Blood Glucose

Postprandial Hyperglycemia

United States
National Cheng-Kung University Hospital

Unknown

The Impact of Tenofovir Alafenamide on Profiles of Body Weight and Metabolic Features in Chronic Hepatitis B Patients. (HBV)

HBV

Taiwan

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