Search clinical trials for: BRCA testing

Total 5971 results

Heinrich-Heine University, Duesseldorf
German Cancer Aid

Not yet recruiting

Prostate Cancer Prevention Clinic for Men With Risk of Familial Prostate Cancer (ProFam-Risk)

Prostate Cancer | Familial Prostate Cancer
Memorial Sloan Kettering Cancer Center

Recruiting

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk

BRCA1 Mutation | BRCA2 Mutation | APC Gene Mutation | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | PTEN Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | POLD1 Gene... and other conditions

United States
Weill Medical College of Cornell University
Basser Research Center for BRCA

Recruiting

FaCT Trial (Facilitated Cascade Testing Trial)

BRCA1 Mutation | BRCA2 Mutation

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

Pancreatic Adenocarcinoma | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Recruiting

Identifying and Caring for Individuals With Inherited Cancer Syndrome

Malignant Solid Neoplasm | Lynch Syndrome | Hematopoietic and Lymphoid System Neoplasm | Breast Ductal Carcinoma In Situ | Hereditary Neoplastic Syndrome | BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome

United States
University of Pennsylvania

Recruiting

Evaluating Cascade Communication Methods (ECHO)

BRCA1 Mutation | BRCA2 Mutation

United States
Boston University
National Institute on Minority Health and Health Disparities (NIMHD); University... and other collaborators

Recruiting

Scalable Communication Modalities for Returning Genetic Research Results (BWHS RoR)

Lynch Syndrome | Hereditary Breast and Ovarian Cancer

United States
Abramson Cancer Center at Penn Medicine
Fox Chase Cancer Center; Merck Sharp & Dohme LLC; AstraZeneca; Basser Center for...

Recruiting

Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients (eReach)

Cancer

United States
NYU Langone Health

Recruiting

Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome

MLH1 Gene Mutation | RAD51C Gene Mutation | BRIP1 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | BRCA-Mutated Ovarian Carcinoma | MSH2 A636P | EPCAM

United States
Memorial Sloan Kettering Cancer Center
Phenogen Sciences

Recruiting

Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations

Genetic Testing | BRCA1/2

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6... and other conditions

United States
ARCAGY/ GINECO GROUP
AstraZeneca

Completed

Genomic BRCA and Extensive ovArian Cancer Testing (GREAT)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Cancer

France
University of Washington
National Cancer Institute (NCI)

Active, not recruiting

Genetic Testing for Men With Metastatic Prostate Cancer (GENTleMEN)

Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I)

Hematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Withdrawn

Testing the Addition of Immunotherapy With Hu5F9-G4 (Magrolimab) to the Usual PARP Inhibitor, Olaparib for Treatment of Metastatic or Recurrent Breast or Castrate-Resistant Prostate Cancer With BRCA Mutations

Anatomic Stage IV Breast Cancer AJCC v8 | Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Unresectable Breast Carcinoma | Metastatic Breast Carcinoma | Locally Advanced Breast Carcinoma | Metastatic HER2-Negative Breast Carcinoma | Unresectable HER2-Negative Breast Carcinoma | Locally Advanced HER2-Negative...

United States
Cancer Trials Ireland

Active, not recruiting

Upfront Systematic Tumour BRCA Testing in Patients With High Grade Serous or Endometrioid Ovarian, Fallopian Tube or Primary Peritoneal Cancer (HGSEC): The t-BRCA Study

Fallopian Tube Cancer | Primary Peritoneal Carcinoma | Serous Ovarian Tumor | Endometrioid Carcinoma Ovary

Ireland
Medical College of Wisconsin

Active, not recruiting

Evaluating the Effects of Genetic Testing on Patients' Stress Levels

Breast Cancer

United States
Institute of Cancer Research, United Kingdom
Cancer Research UK; University of Manchester; University of Sussex

Completed

Digital Delivery of Information About Genetic Testing for Breast Cancer (BRCA-DIRECT)

Breast Neoplasm Female

United Kingdom
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

BRCA and NACT in TNBC Patients (Light-Bright)

Triple-Negative Breast Cancer

Italy
Georgetown University
National Cancer Institute (NCI); National Human Genome Research Institute (NHGRI)

Completed

Decision Support Following Genetic Testing for Breast-Ovarian Cancer Susceptibility

Breast Cancer | Ovarian Cancer

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

A Study of the Communication of Genetic Test Results By Telephone: A Multi-Center Study

Candidates for BRCA 1/2 Genetic Testing

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Genetics and Heart Health After Cancer Therapy (Gene-HEART)

Heart Diseases | Breast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2) | Drug-Induced Cardiomyopathy

United States
European Institute of Oncology

Completed

Promoting Men's Adherence to BRCA1/2 Germline Genetic Testing (BRCA-MEN)

BRCA1 Mutation | BRCA2 Mutation | Psychosocial Factors

Italy
Georgetown University
Virginia Commonwealth University; Basser Center for BRCA; Nueva Vida, Inc.; Capital... and other collaborators

Completed

Enhance the Use of Genetic Counseling and Testing in Latinas

Hereditary Breast and Ovarian Cancer Syndrome

United States
Georgetown University
Virginia Commonwealth University; Cornell University

Completed

Testing an Intelligent Tutoring System to Enhance Genetic Risk Assessment

Hereditary Breast and Ovarian Cancer

United States
AGO Research GmbH

Completed

Prevalence of BRCA in Patients With Ovarian Cancer

Ovarian Cancer | BRCA Status

Germany
Columbia University
American Cancer Society, Inc.

Completed

Decision Support for BRCA Testing in Ethnically Diverse Women

Breast Cancer | Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation

United States
Seoul National University Hospital
Bayer; Korean Society of Breast Imaging & Korean Society For Breast Screening

Unknown

Abbreviated Breast MRI for Second Breast Cancer Detection in Women With BRCA Mutation Testing

Breast Cancer | BRCA1 Mutation | BRCA2 Mutation | Recurrent Breast Cancer | Metachronous Neoplasm

Korea, Republic of
AstraZeneca

Terminated

China Ovarian Cancer BRCA Testing Study (CRONUS)

Ovarian Cancer

China, Hong Kong
AstraZeneca

Completed

FLABRA: Frontline Approach for BRCA Testing in OC Treatment naïve Population. A LATIN AMERICA Epidemiologic Study (FLABRA)

Ovarian Cancer

Brazil, Panama, Colombia, Argentina, Mexico, Peru
German Breast Group
AstraZeneca

Completed

Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency (GeparOla)

Breast Cancer | Triple Negative Breast Neoplasms | HRpos Breast Neoplasms | BRCA 1 /2 and / or HRD

Germany
Igentify Ltd
Sheba Medical Center

Unknown

The Use of Digital Genetic Counselor (DGC) for BRCA1/2 Mutation Carrier Testing

BRCA Mutations
National Cancer Institute (NCI)

Completed

Methods in Education for Breast Cancer Genetics

Breast Cancer | Ovarian Cancer

United States
Lei Li

Unknown

Homologous Recombination Deficiency Status in Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Homologous Recombination Deficiency | Prognosis | Chinese

China
Memorial Sloan Kettering Cancer Center

Completed

Decision-making Regarding Prophylactic Mastectomy and Oophorectomy in Women Seeking Genetic Counseling and Testing for BRCA1/2 Mutations

Breast Cancer | Ovarian Cancer

United States
Severance Hospital

Completed

Testing BRCA 1/2 Mutation Using Next Generation Sequencing (BRCANGS)

Breast Cancer | Breast Neoplasms

Korea, Republic of
Abramson Cancer Center of the University of Pennsylvania

Completed

Multiplex Testing for Evaluation of Breast Cancer Risk, Longitudinal Study

BRCA1/2 Negative

United States
AstraZeneca

Completed

Characterizing the Cross-sectional Approach to Ovarian Cancer: Genetic Testing of BRCA (CHARLOTTE)

Ovarian Cancer

Japan
AstraZeneca
RUSSCO (Russian Society of Clinical Oncology)

Completed

OVArian Cancer Non-Interventional Study - OVATAR (OVATAR)

Ovarian, Peritoneal, Fallopian Tube Cancer, BRCAm+ in Russia

Russian Federation
University Hospital, Montpellier

Completed

Comparison to Psychological, Medical and Emotional Influencing Communication and Achievement Factors to Oncogenetics Tests (PSICOM)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer
Lund University

Completed

Written Genetic Counseling and Mutation Analysis of BRCA1 and BRCA2 to Patients With Breast Cancer (BRCAsearch)

Hereditary Breast Cancer

Sweden
Columbia University

Completed

CBPR - BRCA Genetic Testing Among Orthodox Jews

Breast Cancer

United States
Memorial Sloan Kettering Cancer Center

Withdrawn

Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer

Melanoma | Gastric Cancer | Non-Hodgkin's Lymphoma | Lung Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer | Uterine Cancer | CORPUS UTERI,ENDOMETRIUM | LUNG | OVARY

United States
Memorial Sloan Kettering Cancer Center

Completed

Multiplex Testing for Breast Cancer Susceptibility: A Pilot Study of Subject Preferences for Information and Responses After Testing

Breast Cancer

United States
Memorial Sloan Kettering Cancer Center

Completed

Understanding Decision Making Processes for Undergoing Genetic Testing Among Women With Newly Diagnosed Breast Cancer

Breast Cancer

United States
Georgetown University

Completed

Psychosocial Intervention Pilot for Partners in BRCA Testing

Breast Cancer
AstraZeneca
Optum, Inc.

Completed

Evaluating a Novel Onco-genetic BRCA Testing Counselling Model Among Patients With Ovarian Cancer (ENGAGE)

Epithelial Ovarian/Fallopian Tube/Primary Peritoneal Cancer

United States, Italy, Spain
Georgetown University
National Cancer Institute (NCI); National Human Genome Research Institute (NHGRI)

Completed

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Breast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2)

United States
Northwestern University

Completed

4R for Guideline Indicated BRCA Testing of Breast Center Patients (4R)

Genetic Predisposition to Disease | Newly Diagnosed Carcinoma of Breast

United States

Search clinical trials for: BRCA testing

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