Search clinical trials for: Bioavailability Pharmacokinetic Formulation

Total 16168 results

Shionogi

Recruiting

A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants

Healthy Volunteers

United States
Pfizer

Recruiting

A Study for Two Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Healthy Participants

United States
AstraZeneca

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oral AZD6793 in Healthy Subjects and to Assess the Relative Oral Bioavailability Between Two Formulations. The Study Will Also Assess the Food Effect on the PK of AZD6793 Compared to Fasting State

Inflammatory Diseases

United Kingdom
Karyopharm Therapeutics Inc

Recruiting

Relative Bioavailability/Bioequivalence of Different Formulations of Selinexor, the Impact of Hepatic Impairment on Selinexor Pharmacokinetics, Tolerability and Antitumor Activity of Selinexor Combination Treatment (SPRINT)

Other Solid Tumors | Colorectal Cancer (CRC) | Non-Small Cell Lung Carcinoma (NSCLC)

Israel
Hadassah Medical Organization

Recruiting

Bioequivalence Assessment of Cannabidiol (CBD) Administrated in Oral Formulations

Pain

Israel
ESM Technologies, LLC
The University of Texas Health Science Center, Houston

Active, not recruiting

Bioavailability Evaluation of curQ+ Curcumin Formulation

Bioavailability

United States
Eli Lilly and Company

Completed

A Study to Compare Two Formulations of LY3209590 in Healthy Participants

Healthy

Singapore
Pfizer

Completed

A Study to Investigate the Effect of Tablet Formulation and Food on PF-07104091 in Healthy Participants

Healthy

United States
Factors Group of Nutritional Companies Inc.
Isura

Completed

Pharmacokinetics and Safety of a New Micellar Glutathione Formulation

Bioavailability | Safety

Canada
AbbVie

Completed

Relative Bioavailability of Two Lutikizumab Formulations and Pharmacokinetics, Safety, and Tolerability of Lutikizumab in Chinese Participants

Healthy Volunteers

United States
Medicines for Malaria Venture

Completed

Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers. (PedPQP(BA/FE))

Malaria

Tanzania
Factors Group of Nutritional Companies Inc.
Isura

Completed

Pharmacokinetics of Different CoQ10 Formulations

Coenzyme Q10 Pharmacokinetics

Canada
Factors Group of Nutritional Companies Inc.

Completed

Comparing the Pharmacological Profile of Formulations Containing Omega 3 Fatty Acids

Pharmacokinetics

Canada
Novartis Pharmaceuticals

Terminated

Study to Compare the Pharmacokinetics, Safety and Tolerability of the Pediatric and Adult Branaplam Formulation in Healthy Adults and the Effect of Food on the Latter.

Healthy Volunteers

United Kingdom
Biogen

Completed

A Study to Evaluate the Relative Bioavailability of Two Formulations of BIIB104 and Assess the Effect of Food on the Pharmacokinetics of BIIB104 Following Administration of a Single, Fixed, Oral Dose of BIIB104 in Healthy Participants

Healthy Volunteers

United States
Factors Group of Nutritional Companies Inc.

Completed

Pharmacological Profile of Different Berberine Formulations, and Effects on Blood Sugar Levels

Pharmacokinetics

Canada
University Hospital Inselspital, Berne

Withdrawn

Pharmacokinetic Study to Investigate the Bioavailability and Tolerability of 3 Oral Formulations of Sodium Thiosulfate (TSTS)

Healthy
GlaxoSmithKline

Completed

Comparison of Daprodustat Formulations Produced by Two Methods of Manufacture for Bioequivalence and Dissolution in Healthy Participants

Anaemia

United States
Cinclus Pharma AG

Completed

Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation (BA)

Pharmacokinetics | Bioavailability | Safety

Slovenia
Genentech, Inc.

Completed

A 3-Part Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0980, the Effect of Food, and the Effect of Rabeprazole on the Pharmacokinetics of the Tablet

Healthy Volunteer

United States
Pfizer

Completed

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | NSCLC | Prostate Cancer | Advanced Solid Tumors | Solid Tumors

United States, Australia
Bayer

Completed

Relative Bioavailability and Food Effect Study With Vericiguat to Characterize the Pediatric Formulation in Adult Healthy Subjects

Pharmacokinetics

Germany
Celgene

Completed

A Study to Evaluate the Relative Bioavailability of a Pediatric Granule Formulation of Ozanimod in Healthy Adult Subjects

Healthy Volunteers

United States
AstraZeneca
Parexel

Completed

Study to Assess the Bioavailability of Different Formulations of AZD9977 and Dapagliflozin and Influence of Food in Selected Formulations in Healthy Volunteers

Heart Failure

Germany
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of Modified Release Formulations of Danicopan in Healthy Adult Participants

Healthy

United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Bioequivalence Study of Coated Cesol Tablet Formulation Versus Biltricide

Healthy

Germany
Agios Pharmaceuticals, Inc.

Completed

A Study to Compare the Relative Bioavailability of Two AG-881 Formulations and Evaluate the Effect of Food and Omeprazole on the Pharmacokinetics of AG-881

Healthy Volunteers

United States
AstraZeneca

Completed

A Study to Assess the Reaction of Body for Four Different Formulations of AZD9977 (Part A) and Influence of Food and Lower Dose of a Selected Formulation (Part B) in Healthy Male Subjects

Heart Failure

United Kingdom
AstraZeneca

Completed

A Study to Assess the Relative Bioavailability of 3 Different Formulations Under Fasted and Fed Condition

Chronic Kidney Disease

Germany
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Ziprasidone Pharmacokinetics Using a Reduced Food Effect Formulation Compared to Pharmacokinetics From Commercial Capsules

Healthy

United States
Pfizer

Completed

Study To Assess The Bioequivalence Under Fed And Fasted Conditions Of The Fesoterodine Beads-In-Capsule SR4 And SR7 Formulations And To Estimate The Bioavailability of SR7 Beads Sprinkled On Apple Sauce Relative To The Beads-In-Capsule SR7 Formulation Administer

Neurogenic Detrusor Overactivity

Belgium
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Pilot Open-Label Crossover Bioavailability Study of Celecoxib in Healthy Volunteers

Healthy Volunteers

Singapore
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Pharmacokinetics Of Celecoxib Test Formulations

Healthy Volunteers

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Bioavailability of 3 Sildenafil Oral Disintegrating Tablet Formulations Compared to the Standard Oral Tablet

Healthy Volunteers

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Given With Or Without Food.

Erectile Dysfunction

Singapore
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study To Assess The Pharmacokinetics, Safety, And Tolerability Of A Pregabalin Controlled Release Formulation Administered Following Various Sized Caloric Meals As Compared To The Pregabalin Immediate Release Formulation

Healthy

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Pharmacokinetics of Two Eletriptan Oral Formulations Given With and Without Water and the Commercial Tablet Formulation Given With Water

Healthy Volunteers

Singapore
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A 5-treatment, Study in Healthy Volunteers to Assess The Safety, Tolerability, and Pharmacokinetics of Four Controlled Release (CR) Pregabalin Tablet Formulations and the Immediate Release (IR) Formulation Administered Fasted

Healthy

Belgium
Astellas Pharma Global Development, Inc.
FibroGen

Completed

A Study to Assess the Relative Bioavailability of Roxadustat Following a Single Dose of Pediatric Azo Dye-free Tablet Formulation and Pediatric Azo Dye-free Mini-tablet Formulation Compared to a Single Dose of Azo Dye-containing Tablet Formulation in Healthy Adult Subjects

Healthy Adult Subjects

Germany
Otsuka Pharmaceutical Development & Commercialization...
PRA Health Sciences

Completed

Trial to Assess the Bioavailability of Quetiapine Versus Seroquel® in Subjects With Schizophrenia or Bipolar Disorder

Schizophrenia | Bipolar Disorder

United States
Celgene

Completed

Relative Bioavailability and PPI Effects of CC-92480 Test and Reference Formulations in Healthy Subjects

Healthy Volunteer

United States
AstraZeneca
Quotient Sciences

Completed

AZD4635 Relative Bioavailability Study (Rel Bio)

Healthy Volunteers

United Kingdom
Food and Drug Administration (FDA)
Algorithme Pharma Inc; Vince & Associates Clinical Research, Inc.

Completed

A Bioavailability Crossover Study of Two Formulations of Lamotrigine Extended Release Tablets in Healthy Subjects

Healthy

United States
Celgene

Completed

Bioavailability of Enasidenib (CC-90007) Sprinkle Formulation Relative to the Reference Tablet Formulation and Effect of Food on the Pharmacokinetics of Sprinkle Formulation in Healthy Adults

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Relative Oral Bioavailability of a Single Dose of JNJ-53718678 Administered as Oral Concept Formulation Compared to the Current Oral Solution and to Assess the Effect of Food on the Pharmacokinetics of Oral Concept Formulation

Healthy

Belgium
Sucampo Pharma Americas, LLC
Takeda

Completed

Comparative Pharmacokinetics and Food-Effect Bioavailability of Lubiprostone Sprinkle in Healthy Volunteers

Healthy Volunteers

United States
Bausch Health Americas, Inc.

Completed

Pharmacokinetics and Bioavailability Comparison of Two Different Formulations of MNTX Tablets

Normal Volunteers

United States
Pfizer

Completed

Evaluate Taste and Relative Bioavailability of Two Microsphere Formulations of Crizotinib in Healthy Participants

Healthy Volunteers

United States
Pfizer

Completed

Bioavailability Study of PF-06651600 Formulations in Healthy Participants

Healthy Volunteers

Belgium
ViiV Healthcare

Completed

A Study to Compare the Relative Bioavailability of Two Different Formulations of GSK3640254

HIV Infections

United Kingdom

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