Search clinical trials for: Cell Senescence

Total 49329 results

Trio Fertility

Recruiting

Senescent Endometrial Cells in Patients With Thin Endometrial Lining

Asherman's Syndrome | Thin Endometrial Lining | Cell Senescence

Canada
Universidade Federal Fluminense

Not yet recruiting

Effects of Royal Jelly Supplementation in Chronic Kidney Disease

Hemodialysis | Kidney Failure, Chronic | Oxidative Stress

Brazil
National Institute of Medical Sciences and Nutrition...

Not yet recruiting

Adversity and Its Association With the Development and Expression of Rheumatic Diseases (RD)

RhA - Rheumatoid Arthritis
Fundación IVI
Instituto Valenciano de Infertilidad, IVI VALENCIA

Recruiting

Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation (HormoSenoRec)

Endometrial Receptivity

Spain
Odense University Hospital
Novo Nordisk A/S; Odense Patient Data Explorative Network

Recruiting

Senolytics to Improve Osteoporosis Therapy (SENIOR)

Osteopenia, Osteoporosis

Denmark
Yonsei University

Recruiting

Effect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Type 2 Diabetes

Diabetes Mellitus | Sodium-Glucose Transporter 2 Inhibitors | Cellular Senescence

Korea, Republic of
Tianjin Medical University

Recruiting

Peripheral Treg Cell Senescence & Serum Total Cholesterol Level

Hypercholesterolemia

China
Cedars-Sinai Medical Center
National Institute on Aging (NIA)

Recruiting

Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

Obesity | Healthy Lifestyle

United States
Cliniques universitaires Saint-Luc- Université...

Recruiting

Nasal Brushing for the Diagnosis and Understanding of Telomeropathies (TELOSTIC)

Telomere Shortening | Telomere Disease

Belgium
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Recruiting

Characterization of the microVAScular Dysfunction in Covid-19 ARDS (VASCOV)

ARDS, Human | COVID-19 Acute Respiratory Distress Syndrome

France
St. Jude Children's Research Hospital
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer

Frailty | Childhood Cancer

United States
Sundeep Khosla, M.D.

Active, not recruiting

Targeting Cellular Senescence With Senolytics to Improve Skeletal Health in Older Humans

Healthy

United States
Mayo Clinic

Enrolling by invitation

Cellular Senescence and COVID-19 Long-Hauler Syndrome

SARS-CoV2 Infection

United States
Vitality in Aging Research Group, Inc.

Withdrawn

VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements

Aging
Memorial Sloan Kettering Cancer Center
Brigham and Women's Hospital; Weill Medical College of Cornell University; The... and other collaborators

Completed

Cognitive Changes Associated With Breast Cancer Treatment

Breast Cancer | Cognitive Side Effects of Cancer Treatments | Stage I, II and III A Breast Cancer

United States
Central Hospital, Nancy, France

Suspended

PROGENitors, TELomeres and ARTerial Aging (PROGENTELART)

Atherosclerosis of Artery

France
Arbor Life Labs

Completed

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Male Subjects With Hair Loss (REBOOT-MEN)

Androgenetic Alopecia | Androgenic Alopecia | Hair Loss/Baldness | Hair Thinning | Telogen Effluvium | Thinning Hair

United States
Arbor Life Labs

Completed

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Female Subjects With Hair Loss (REBOOT-WOMEN)

Androgenetic Alopecia | Androgenic Alopecia | Hair Loss/Baldness | Hair Thinning | Telogen Effluvium | Thinning Hair

United States
Smith & Nephew, Inc.

Terminated

A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention (WoundWand)

Lower Leg Wound

France, United Kingdom
Centre d'Alt Rendiment
University of Barcelona; Indena S.p.A; Hospital Sant Joan de Deu

Completed

Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes (CoQ10Sport)

Aging | Oxidative Stress | Coenzyme Q10

Spain
Hospices Civils de Lyon

Completed

Premature Aging and Type 2 Diabetes Mellitus: an Increased Risk of Cardiomyopathy? (R2D2)

Type 2 Diabetes Mellitus

France
South China Research Center for Stem Cell and Regenerative...

Unknown

Safety Study of Filler Agent Composed of Umbilical Cord Mesenchymal Stem Cells and Hyaluronic Acid

Senescence Wrinkles, Acne, Pitting Scar
Assistance Publique Hopitaux De Marseille

Completed

IN UTERO SMOKING AND PREMATURE CELLULAR SENESCENCE

Chronic Obstructive Pulmonary Disease

France
Regeneron Pharmaceuticals

Not yet recruiting

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

AGNOSTIC THERAPY IN A PHASE II SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB IN ASSOCIATION WITH CARBOPLATIN OR CISPLATIN AND ETOPOSIDE IN PATIENTS AFFECTED BY EXTENSIVE STAGE - EXTRAPULMONARY SMALL CELL CARCINOMA (DURVASCC)

Extrapulmonary Small Cell Carcinoma

Italy
First Affiliated Hospital of Zhejiang University
First Affiliated Hospital of Wenzhou Medical University; The Affiliated Hospital... and other collaborators

Recruiting

Primary Multiple Myeloma Who Achieved MRD Negativity After Induction Therapy, ASCT or Not

Multiple Myeloma | Minimal Residual Disease

China
The First Affiliated Hospital of Xiamen University

Recruiting

ImmunoPET Targeting Trophoblast Cell-Surface Antigen 2 (Trop-2) in Thyroid Cancer

Solid Tumor | Thyroid Cancer | Tumor | Positron-Emission Tomography

China
Milton S. Hershey Medical Center
Aminex Therapeutics, Inc.

Not yet recruiting

Difluoromethylornithine (DFMO) and AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Ewing Sarcoma | Embryonal Tumor With Multilayered Rosettes | Osteosarcoma Recurrent | Atypical Teratoid/Rhabdoid Tumor | DIPG Brain Tumor | Neuroblastoma Recurrent
Hunter Holmes Mcguire Veteran Affairs Medical Center

Recruiting

Microbiome Modulation With Prebiotics in PTSD and Cirrhosis (RESIST-PTSD)

PTSD | Cirrhosis

United States
Institute of Hematology & Blood Diseases Hospital...

Recruiting

A Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

China
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma (CD19-CARNK/T)

Mantle Cell Lymphoma (MCL) | Primary Mediastinal B-cell Lymphoma (PMBCL) | Diffuse Large B Cell Lymphoma( DLBCL)
Nanjing IASO Biotechnology Co., Ltd.

Recruiting

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03) (FUMANBA-03)

Multiple Myeloma

China
Fujian Cancer Hospital

Recruiting

A Study of Sintilimab Combined With Chemotherapy for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Sohag University

Recruiting

Identification of Pattern and Factors Affecting Recurrence in Head and Neck Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma

Egypt
Genelux Corporation
Newsoara Biopharma Co., Ltd.

Not yet recruiting

Efficacy & Safety of Olvimulogene Nanivacirepvec and Platinum-doublet + Physician's of Choice Immune Checkpoint Inhibitor Compared With Docetaxel in NSCL Cancer (VIRO-25) ((VIRO-25))

Non-small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer | Advanced Non-squamous Non-small-cell Lung Cancer | Non-small Cell Lung Cancer Stage IV | Metastatic Squamous Non-Small Cell Lung Carcinoma | Non-small Cell Lung Cancer Recurrent | Metastatic Non-squamous Non Small Cell Lung Cancer and other conditions
Minovia Therapeutics Ltd.

Recruiting

A Phase Ib Study to Evaluate the MNV-201 in Patients With Low Risk MDS

Myelodysplastic Syndromes

Israel
Henan Cancer Hospital

Not yet recruiting

Clinical Study of SHR-A1921 or SHR-A2009 in Previously Treated Advanced NSCLC

NSCLC

China
Emory University
The Marcus Foundation

Not yet recruiting

A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)

Dilated Cardiomyopathy

United States
Hackensack Meridian Health
Preprogen

Recruiting

Endometrial Cell Collection With the PadKit

Neoplasms

United States
Seattle Children's Hospital

Not yet recruiting

REACT-01: Reversing Autoimmunity Through Cell Therapy

Systemic Lupus Erythematosus

United States
National Cancer Institute (NCI)

Not yet recruiting

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Hard-to-Treat Multiple Myeloma

Multiple Myeloma
Eli Lilly and Company
Loxo Oncology, Inc.

Not yet recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (NEXUS-01)

Cervical Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Renal Pelvis Cancer | Urinary Bladder Neoplasm | Recurrent...

United States
University Hospital, Strasbourg, France

Recruiting

Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring (OPTIMDREP)

Sickle Cell Disease

France
Zhejiang Provincial People's Hospital
Zhejiang University; Hangzhou RonGu Biotechnology Limited Company

Not yet recruiting

Clinical Study of Cord Blood-Derived CAR-NK Cells in Gastric Cancer and Pancreatic Cancer

Gastric Cancer | Pancreas Adenocarcinoma

China
Changhai Hospital
Rui Therapeutics

Not yet recruiting

An Exploratory Clinical Study of CD19 CAR NK Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

Autoimmune Diseases
Wuhan Union Hospital, China
Wuhan Hamilton Biotechnology Co., Ltd; Guangzhou Hamilton Biotechnology Co....

Not yet recruiting

Phase I Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis
Tr1X, Inc.

Recruiting

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

Myelodysplastic Syndromes | Hematologic Malignancy | Hematopoietic Stem Cell Transplant | Acute Myeloid Leukemia in Remission | GVHD, Chronic | GVHD,Acute | GvHD | Acute Lymphoblastic Leukemia, Adult B-Cell | Cancer Remission | Acute Lymphoblastic Leukemia, Adult T-Cell | Chronic Myelomonocytic Leukemia,...

United States
Zhejiang University
Carbiogene Therapeutics Co. Ltd.

Not yet recruiting

Clinical Trial of Autologous GPC3 CAR-T Cells (CBG166) Therapy for Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
NYU Langone Health

Not yet recruiting

Packed Red Blood Cell Transfusion During Cardiac Arrest

Cardiac Arrest

United States
Shanghai Pulmonary Hospital, Shanghai, China
Shanghai Zhongshan Hospital; The First Affiliated Hospital of Xiamen University

Not yet recruiting

Phase II Trial of Almonertinib Plus Lastet for EGFR+ Non-small Cell Lung Cancer

Lung Cancer Non-small Cell Stage IV

China

Search clinical trials for: Cell Senescence

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