Search clinical trials for: Cell senescence

Total 49200 results

Universidade Federal Fluminense

Not yet recruiting

Effects of Royal Jelly Supplementation in Chronic Kidney Disease

Hemodialysis | Kidney Failure, Chronic | Oxidative Stress

Brazil
National Institute of Medical Sciences and Nutrition...

Not yet recruiting

Adversity and Its Association With the Development and Expression of Rheumatic Diseases (RD)

RhA - Rheumatoid Arthritis
Fundación IVI
Instituto Valenciano de Infertilidad, IVI VALENCIA

Recruiting

Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation (HormoSenoRec)

Endometrial Receptivity

Spain
Odense University Hospital
Novo Nordisk A/S; Odense Patient Data Explorative Network

Recruiting

Senolytics to Improve Osteoporosis Therapy (SENIOR)

Osteopenia, Osteoporosis

Denmark
Yonsei University

Recruiting

Effect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Type 2 Diabetes

Diabetes Mellitus | Sodium-Glucose Transporter 2 Inhibitors | Cellular Senescence

Korea, Republic of
Tianjin Medical University

Recruiting

Peripheral Treg Cell Senescence & Serum Total Cholesterol Level

Hypercholesterolemia

China
Cedars-Sinai Medical Center
National Institute on Aging (NIA)

Recruiting

Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

Obesity | Healthy Lifestyle

United States
Cliniques universitaires Saint-Luc- Université...

Recruiting

Nasal Brushing for the Diagnosis and Understanding of Telomeropathies (TELOSTIC)

Telomere Shortening | Telomere Disease

Belgium
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Recruiting

Characterization of the microVAScular Dysfunction in Covid-19 ARDS (VASCOV)

ARDS, Human | COVID-19 Acute Respiratory Distress Syndrome

France
St. Jude Children's Research Hospital
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer

Frailty | Childhood Cancer

United States
Sundeep Khosla, M.D.

Active, not recruiting

Targeting Cellular Senescence With Senolytics to Improve Skeletal Health in Older Humans

Healthy

United States
Mayo Clinic

Enrolling by invitation

Cellular Senescence and COVID-19 Long-Hauler Syndrome

SARS-CoV2 Infection

United States
Vitality in Aging Research Group, Inc.

Withdrawn

VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements

Aging
Memorial Sloan Kettering Cancer Center
Brigham and Women's Hospital; Weill Medical College of Cornell University; The... and other collaborators

Completed

Cognitive Changes Associated With Breast Cancer Treatment

Breast Cancer | Cognitive Side Effects of Cancer Treatments | Stage I, II and III A Breast Cancer

United States
Central Hospital, Nancy, France

Suspended

PROGENitors, TELomeres and ARTerial Aging (PROGENTELART)

Atherosclerosis of Artery

France
Arbor Life Labs

Completed

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Male Subjects With Hair Loss (REBOOT-MEN)

Androgenetic Alopecia | Androgenic Alopecia | Hair Loss/Baldness | Hair Thinning | Telogen Effluvium | Thinning Hair

United States
Arbor Life Labs

Completed

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Female Subjects With Hair Loss (REBOOT-WOMEN)

Androgenetic Alopecia | Androgenic Alopecia | Hair Loss/Baldness | Hair Thinning | Telogen Effluvium | Thinning Hair

United States
Smith & Nephew, Inc.

Terminated

A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention (WoundWand)

Lower Leg Wound

France, United Kingdom
Centre d'Alt Rendiment
University of Barcelona; Indena S.p.A; Hospital Sant Joan de Deu

Completed

Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes (CoQ10Sport)

Aging | Oxidative Stress | Coenzyme Q10

Spain
Hospices Civils de Lyon

Completed

Premature Aging and Type 2 Diabetes Mellitus: an Increased Risk of Cardiomyopathy? (R2D2)

Type 2 Diabetes Mellitus

France
South China Research Center for Stem Cell and Regenerative...

Unknown

Safety Study of Filler Agent Composed of Umbilical Cord Mesenchymal Stem Cells and Hyaluronic Acid

Senescence Wrinkles, Acne, Pitting Scar
Assistance Publique Hopitaux De Marseille

Completed

IN UTERO SMOKING AND PREMATURE CELLULAR SENESCENCE

Chronic Obstructive Pulmonary Disease

France
Taizhou Hospital

Not yet recruiting

Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Cell (SCLC)

SCLC | Maintenance Treatment
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States
University Hospital, Brest

Not yet recruiting

Impact of Respiratory Rehabilitation on Quality of Life in Patients With Metastatic Non-small Cell Lung Cancer Treated With Immunotherapy and Chemotherapy in the Maintenance Phase (REHABIM)

Cancer
Fujian Medical University Union Hospital

Recruiting

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder Neoplasms | Treatment Outcome | Neoplasm Recurrence, Local | Multicenter Study | Immunotherapy, Active | BCG Vaccine

China
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Retrospective-prospective Study to Evaluate Treatment Management and Outcomes of Patients With Waldenström's Macroglobulinemia (WM) Treated in Italy According to the Zanubrutinib (Brukinsa®) Compassionate Use Program (CUP) and in Common Practice Following Commercial Approval.

Waldenström's Macroglobulinemia (WM)

Italy
University of Washington

Not yet recruiting

Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphoma

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma | Ann Arbor Stage II Marginal Zone Lymphoma | Ann Arbor Stage III Marginal Zone Lymphoma and other conditions

United States
Ruijin Hospital

Not yet recruiting

Efficacy of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL

Diffuse Large B-Cell Lymphoma
St. Jude Children's Research Hospital
BioLineRx, Ltd.

Not yet recruiting

SCD Stem Cell Mobilization and Apheresis Using Motiixafortide

Sickle Cell Disease

United States
Instituto do Cancer do Estado de São Paulo

Not yet recruiting

Study to Compare Two Partial Nephrectomy Techniques for Renal Tumors: Robot-assisted vs Videolaparoscopic (VPN x RANP)

Renal Cancer
Hunan Province Tumor Hospital
Hunan Cancer Hospital

Recruiting

Efficacy and Resistance Mechanisms of IP in NSCLC With Leptomeningeal Metastases (EPIC)

Non-Small Cell Lung Cancer

China
University of Utah
Georgetown University; West Virginia University

Recruiting

Rural Adult and Youth Sun Protection Study (RAYS)

Skin Cancer | Melanoma (Skin)

United States
Ruijin Hospital

Not yet recruiting

Blinatumomab Maintenance After Allo-HSCT

High Risk Acute Lymphoblastic Leukemia
Chinese University of Hong Kong

Not yet recruiting

Diagnostic Utility of Mycobacterium Tuberculosis Cell-free DNA (MYDNITE)

Tuberculosis, Pleural
Nerissa T. Viola

Not yet recruiting

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy

Non Small Cell Lung Cancer

United States
Istituti Clinici Scientifici Maugeri SpA

Not yet recruiting

Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation.

Chronic Obstructive Pulmonary Disease | Respiratory Failure

Italy
National Cancer Institute (NCI)

Not yet recruiting

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Metastatic Urothelial Carcinoma | Unresectable Urothelial Carcinoma
Massachusetts General Hospital

Not yet recruiting

Ziftomenib Maintenance Post Allo-HCT

Acute Myeloid Leukemia | Acute Myeloid Leukemia in Remission | NPM1 Mutation | KMT2A Rearrangement

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Neuroendocrine Carcinoma.

Neuroendocrine Carcinoma

China
Virginia Commonwealth University

Not yet recruiting

CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial (CBT-I in PBT)

Glioblastoma | Astrocytoma | Oligodendroglioma | Meningioma | Primary Brain Tumor | Primary Central Nervous System (CNS) Lymphoma

United States
Medical University of Lublin

Recruiting

Relationship Between Circulating Sclerostin and Bone Lesions in Patients With Mastocytosis

Mastocytosis | Bones

Poland
Instituto de Investigación Biomédica de Salamanca
Carlos III Health Institute

Recruiting

Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment

Diffuse Large B Cell Lymphoma

Spain
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) (SPARKLE)

Sickle Cell Disease
King's College Hospital NHS Trust

Recruiting

The Incidence and Outcomes of Metabolically Active Brown Adipose Tissue (aBAT) in Patients With Pheochromocytoma or Paraganglioma (PPGLs)

Pheochromocytoma | Paraganglioma

United Kingdom
Main Line Health
Pfizer; Sumitomo Pharma America, Inc.

Not yet recruiting

The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial

Endometriosis

United States
Nuritas Ltd

Recruiting

A Study to Determine the Safety and Tolerability of a Range of Doses of PeptiControl in Pre-diabetic Individuals

Overweight | Pre Diabetes

India
Mayo Clinic

Recruiting

Fasting Mimicking Diet for Reducing Immune Related Adverse Events for Cancer Patients on Immune Checkpoint Inhibitors, FMD-ICI Trial

Malignant Solid Neoplasm | Melanoma | Renal Cell Carcinoma | Lung Non-Small Cell Carcinoma | Urothelial Carcinoma | Lung Small Cell Carcinoma

United States
Cardarelli Hospital

Not yet recruiting

NBI for Early Diagnosis of OPMD/OSCC (NBI_Oral)

Oral Squamous Cell Carcinoma | Oral Potentially Malignant Disorder

Italy
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.

Not yet recruiting

Umbilical-Cord-Derived Mesenchymal Stem Cells Injection for Chronic Radiation Proctitis

Chronic Radiation Proctitis

Search clinical trials for: Cell senescence

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