Search clinical trials for: Clinical pharmacology

Total 59183 results

Wright State University

Recruiting

The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population

Aging | Actinic Keratoses | Non-Melanoma Skin Cancer

United States
Peking University Third Hospital

Not yet recruiting

A Clinical Pharmacological Study of Dose Halving of Dexamethasone in Pregnant Women With Preterm Labour With Preterm Birth at Greater Than or Equal to 34 Gestational Weeks (34GW+)

Respiratory Distress Syndrome of Newborn
Wright State University

Recruiting

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Rosacea

United States
Calico Life Sciences LLC
AbbVie

Recruiting

A Thorough QT Study of ABBV-CLS-7262 in Healthy Subjects

Healthy

United States
Universitätsklinikum Hamburg-Eppendorf

Not yet recruiting

Intermittent Hypoxemia, Lung Function Decline, Morbidity, and Mortality in COPD (PROSA Study). (PROSA)

Chronic Obstructive Pulmonary Disease (COPD)

Germany
Materia Medica Holding

Recruiting

Clinical Trial of the Efficacy and Safety of Raphamin in Combined Treatment of Community-acquired Pneumonia

Pneumonia | Community-acquired Pneumonia

Russian Federation
NeuroBo Pharmaceuticals Inc.

Recruiting

First in Human Study in Subjects With Obesity, But Otherwise Healthy

Obesity

United States
Helsinki University Central Hospital
University of Helsinki

Recruiting

KF2022#3-trial: Effect of Tea and Cola Beverage on Absorption of Risperidone Oral Solution (KF2022#3)

Psychosis | Food-drug Interaction

Finland
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
University Hospital, Basel, Switzerland

Not yet recruiting

Acute Analgesic Effects of DMT on Experimentally Induced Pain in Healthy Participants (DPS)

Healthy

Switzerland
Ahon Pharmaceutical Co., Ltd.

Recruiting

Phase 1 Hepatic Insufficiency Trial of Methoxyethyl Etomidate Hydrochloride

Hepatic Insufficiency

China
Eli Lilly and Company

Recruiting

A Study of LY3971297 in Healthy Participants and Participants With Obesity and Hypertension

Hypertension | Healthy | Obesity

United States, Singapore
BioMarin Pharmaceutical

Recruiting

A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria

Nonalcoholic Fatty Liver Disease | Kidney Stone | Hyperoxaluria

United States
Intellia Therapeutics
Regeneron Pharmaceuticals

Recruiting

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Australia, United Kingdom, New Zealand, Canada
Mikkel Bring Christensen

Recruiting

Postprandial Profiles of Metabolites and Appetite-regulating Hormones in Plasma and Cerebrospinal Fluid

Obesity | Diabetes Mellitus, Type 2

Denmark
ProMis Neurosciences, Inc

Recruiting

A Phase 1a Study of PMN310 In Healthy Volunteers

Healthy Participants

United States
NeuroBo Pharmaceuticals Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed NASH

NON-ALCOHOLIC STEATOHEPATITIS

United States
Merck Sharp & Dohme LLC

Recruiting

A Study of Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014)

Hepatic Impairment | Non-alcoholic Steatohepatitis

United States
Universitaire Ziekenhuizen KU Leuven
Innovative Medicines Initiative; BELpREG

Recruiting

UmbrelLACT Study: Clinical Lactation Study on the Exposure to Medicines Via Human Milk (UmbrelLACT)

Breast Feeding | Human Milk

Belgium
Chiesi Farmaceutici S.p.A.

Recruiting

Efficacy and Safety of Tanimilast in Asthmatics uNcontrolled on ICS-containinG backgrOund Maintenance Therapy (TANGO)

Uncontrolled Asthma

Argentina, Bulgaria, Czechia, Georgia, Germany, Hungary, Italy, Korea, Republic of, Latvia, Lithuania, Poland, Romania, South Africa, Spain
University of California, San Francisco
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Not yet recruiting

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration (CANNIC)

Tobacco Use | Cannabis | Cannabis Use | Vaping | THC | Cannabis Smoking

United States
Boehringer Ingelheim

Recruiting

A Study to Test How Well Different Doses of BI 3006337 Are Tolerated by People With Overweight or Obesity and With Fatty Liver Disease

Obesity | Non-alcoholic Fatty Liver Disease

United States
Bayer

Recruiting

A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes (FINE-ONE)

Chronic Kidney Disease | Type 1 Diabetes Mellitus

United Kingdom, United States, Korea, Republic of, Denmark, Germany, Italy, China, Spain, Canada
Chiesi Farmaceutici S.p.A.
SGS S.A.

Recruiting

Clinical Study to Evaluate the Safety, Tolerability and the Concentration of the BDP (Beclomethasone Dipropionate), Active Metabolite of BDP, FF( Formoterol Fumarate) and GB (Glycopyrronium Bromide), After Inhalation of CHF 5993 at Two Different Doses and QVAR®

Asthma

Belgium
Eli Lilly and Company

Recruiting

A Study of LY3502970 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Beckley Psytech Limited

Recruiting

BPL-003 Efficacy and Safety in Treatment Resistant Depression

Treatment Resistant Depression

Spain, Germany, United States, Poland, Australia, United Kingdom
Clinical Centre of Serbia
Faculty of Medicine, University of Belgrade

Recruiting

Oxidative Stress and Inflammation Biomarkers in Surgically Treated Patients With Laryngeal Cancer

Quality of Life | Pain, Postoperative | Laryngeal Cancer | Pain Management | Oxidative Stress Induction | Interleukins

Serbia
AbbVie

Recruiting

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus (SELECT-SLE)

Systemic Lupus Erythematosus

United States, Japan, Puerto Rico, Switzerland, Israel, Korea, Republic of, Hungary, New Zealand, Bulgaria, Latvia, Taiwan, Slovakia, Croatia, South Africa, Australia, Poland, Portugal, Spain, Estonia, France, Lithuania, Brazil, Ger... and more
PainReform LTD
Lotus Clinical Research, LLC

Recruiting

A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain

Bunion

United States
AbbVie

Recruiting

Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-552 Capsules Moves Through the Body of Participants Aged 50 to 90 Years With Mild Alzheimer's Disease

Alzheimer's Disease (AD)

United States, Japan, New Zealand, Australia, Spain, Germany, United Kingdom
Gilead Sciences

Recruiting

Study of Bulevirtide in Participants Who Have Normal or Impaired Liver Function

Chronic Hepatitis D Infection

United States
Gilead Sciences

Recruiting

A Multiple-Dose Study of Bulevirtide in Participants With Normal and Impaired Renal Function

Chronic Hepatitis D Infection

United States
Centre of Clinical Pharmacology, Hanoi Medical...

Not yet recruiting

Efficacy and Safety of DT01 Tablets in Patients With Irritable Bowel Syndrome With Diarrhea

Irritable Bowel Syndrome With Diarrhea

Vietnam
University Hospital, Basel, Switzerland

Not yet recruiting

Acute Dose-dependent Effects of DMT-bolus Applications in Healthy Subjects (DMT BDR-Study) (DMT BDR)

Healthy

Switzerland
Wright State University

Recruiting

The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy

Actinic Keratosis | Photodynamic Therapy | Imipramine

United States
Xilio Development, Inc.

Recruiting

XTX301 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

United States
Ionis Pharmaceuticals, Inc.
AstraZeneca

Recruiting

An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

United States, Austria, Belgium, Canada, France, Germany, Israel, Italy, Portugal, Spain, Sweden, United Kingdom, Australia, Greece
Medical University of Vienna

Recruiting

Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19

COVID-19 | Post-COVID-19 Syndrome

Austria
Federation Bio Inc.

Recruiting

Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria

Healthy | Enteric Hyperoxaluria

United States
Clarametyx Biosciences, Inc.

Recruiting

A 2-Part First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of CMTX-101

Community-acquired Pneumonia | Bacterial Pneumonia

United States
Odense University Hospital

Recruiting

Thromboembolism in Anorexia Nervosa (TEAN)

Anorexia Nervosa | Thrombosis | Thromboembolism

Denmark, Sweden
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Short-course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer

Radiotherapy | Rectal Neoplasms Malignant

China
Amgen

Recruiting

Single and Multiple Ascending Dose Study to Evaluate AMG 786 in Healthy Participants and Participants With Obesity

Obesity

United States
Grünenthal GmbH

Recruiting

Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee

Osteoarthritis

Japan, United States, South Africa, Bulgaria, Poland, Romania, United Kingdom
Helsinki University Central Hospital
University of Helsinki

Recruiting

KF2019#1-trial: Effects of a Thrombocyte Inhibitor on a Cholesterol-lowering Drug (KF2019#1)

Pharmacokinetics

Finland
Genentech, Inc.

Recruiting

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With The Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer

Korea, Republic of, United States, Spain, Taiwan, United Kingdom, Japan, Germany, Argentina, Turkey, Greece, Italy, Singapore, South Africa
Medical University of Vienna

Recruiting

The Effect of Antibiotic Eye Drops on the Nasal Microbiome in Healthy Subjects

Nasal and Pharyngeal Microbiome

Austria
Bayer

Recruiting

A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes (CONFIDENCE)

Type 2 Diabetes Mellitus | Chronic Kidney Disease

United States, Belgium, Spain, Taiwan, Korea, Republic of, Japan, Italy, Denmark, Israel, Canada, France, India, Netherlands, Germany
RWTH Aachen University
B. Braun-Stiftung

Not yet recruiting

Individual Risk Profiles for Adverse Drug Reactions in Geriatric Patients

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Polypharmacy | Pharmacogenomic Testing
Psychiatric Research Unit, Region Zealand, Denmark
Region Zealand; Steno Diabetes Center Sjaelland

Not yet recruiting

Medication Review in Patients With Schizophrenia and Diabetes

Diabetes | Schizophrenia | Metabolic Syndrome

Search clinical trials for: Clinical pharmacology

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