Search clinical trials for: Cross-over multicenter trial

Total 43263 results

Sanquin Research & Blood Bank Divisions
Radboud University Medical Center; Maastricht University Medical Center; UMC... and other collaborators

Unknown

Assessment of the Mu-Drop System for Serum Eye Drops (AmuSED)

Dry Eye Syndrome

Netherlands
Amsterdam UMC
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Preeclampsia Intervention Netherlands (PI-NL)

Pre-Eclampsia | HELLP Syndrome | Pre-eclampsia or Eclampsia With Pre-existing Hypertension | HELLP | Pre-Eclampsia; Complicating Pregnancy | Pre-Eclampsia Onset Less Than 37 Weeks | Pre-Eclampsia as Antepartum Condition | Pre-Eclampsia; Affecting Fetus | HELLP Syndrome Complicating Pregnancy
Fujian Medical University Union Hospital

Recruiting

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder Neoplasms | Treatment Outcome | Neoplasm Recurrence, Local | Multicenter Study | Immunotherapy, Active | BCG Vaccine

China
Hospital Italiano de Buenos Aires

Not yet recruiting

Mortality of MBL-producing Enterobacteriaceae Bacteremias With the Combined Use of Ceftazidime-avibactam and Aztreonam vs. Other Active Antibiotics. A Multicenter Target Trial Emulation.

Bacteremia
Bayer

Recruiting

A Study to Learn About Whether BAY H006689 Causes an Allergic Reaction When Applied as a Topical Gel in Healthy Participants

Pain | Healthy Volunteers

United States
KidSIM Simulation Program
University of Alabama at Birmingham; Columbia University; University of Southern... and other collaborators

Not yet recruiting

Evaluation of the InterFACE-AR System for Cardiopulmonary Arrest: A Multicenter, Randomized Controlled Trial (InterFACE-AR)

Cardiac Arrest | Cardiopulmonary Arrest
Peking University First Hospital

Recruiting

Comparison of MRI Artificial Intelligence-guided cTB Versus Routine cTB in Prostate Cancer Diagnosis

Prostate Cancer

China
Intra-Cellular Therapies, Inc.

Recruiting

Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

Bipolar Depression

United States
Jing-yuan Fang, MD, Ph. D

Recruiting

Tislelizumab With Fruquintinib, Metronidazole, in Mismatch Repair-proficient or Microsatellite Stability, Advanced Colorectal Cancer: a Multicenter, Single Arm, Clinical Trial

Colorectal Cancer

China
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Immediate Corticosteroid Therapy and Rituximab to Prevent Generalization in Ocular Myasthenia: a PROBE Multicenter Open-label Randomized Controlled Trial. (IMCOMG)

Ocular Myasthenia Gravis
Major Extremity Trauma Research Consortium

Not yet recruiting

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures: A Multicenter Randomized Controlled Trial (iVAC)

Wound Heal | Wound Complication | Wound Dehiscence | Fracture of Tibia | Infected Wound
Peking University First Hospital

Recruiting

Fuzheng Nizeng Formula for Chronic Atrophic Gastritis With Low-grade Intraepithelial Neoplasia, a Multicenter Randomized Controlled Trial

Atrophic Gastritis With Low-grade Intraepithelial Neoplasia

China
Beijing Tiantan Hospital

Not yet recruiting

Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke (TAPIS)

Ischemic Stroke, Acute
Zhejiang Cancer Hospital

Not yet recruiting

Eribulin Combined With Sintilimab as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Breast Cancer:A Multicenter, Single-arm,Phase II Clinical Trial

Metastatic Breast Cancer

China
The Fourth Affiliated Hospital of China Medical...

Recruiting

A Prospective, Experimental, Multicenter, Open-label, Randomized, Controlled Trial of 3-month Dual Antiplatelet Therapy Followed by Ticagrelor Versus 6-month Dual Antiplatelet Therapy Followed by Ticagrelor After Implanting Bridge

Brain Disease | Vertebral Artery Stenosis

China
Huashan Hospital

Recruiting

aSAH Treatment Based on Intraventricular ICP Monitoring: A Prospective, Multicenter, Randomized and Controlled Trial (ASTIM-MT)

Intracranial Pressure Increase | Aneurysmal Subarachnoid Hemorrhage

China
Peking University Third Hospital
Beijing Yanqing Hospital

Recruiting

A Prospective Multicenter Cohort Study About Internal Fixation Using PFUN Versus PFNA for Femoral Intertrochanteric Fracture

Femoral Intertrochanteric Fractures

China
Auckland City Hospital

Not yet recruiting

Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery (Balanced-2)

Delirium | Anesthesia | Cognitive Decline | Cognition Disorder | Surgery-Complications | Delirium, Postoperative
University Hospital, Tours
Hospices Civils de Lyon; Centre Hospitalier Universitaire Dijon; CHU de Reims; University... and other collaborators

Not yet recruiting

Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial (CARVECIR)

Clinically Significant Portal Hypertension | Asymptomatic Cirrhosis

France
The Third People's Hospital of Hangzhou
The Third Affiliated hospital of Zhejiang Chinese Medical University

Recruiting

Efficacy of Electroacupuncture Combined With Pregabalin in the Treatment of Trigeminal Herpetic Neuralgia: a Multicenter Randomized Controlled Trial Study Protocol

Trigeminal Herpetic Neuralgia

China
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

Investigating the Safety and Efficacy of SHR6508 Injection in the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients : A Multicenter, Long-term Clinical Trial

Secondary Hyperparathyroidism (SHPT) in Subjects With Chronic Kidney Disease (CKD) on Hemodialysis

China
Wuhan Union Hospital, China

Recruiting

The Prognostic Value of CPCs Quantified by Flow Cytometry in Patients With Multiple Myeloma: a Prospective, Multicenter Clinical Trial

Multiple Myeloma

China
BioMarin Pharmaceutical

Recruiting

A Multicenter Multinational Observational Study of Children With Hypochondroplasia

Hypochondroplasia

United States, Spain, Canada, France, Japan, Australia, Italy, Argentina, Brazil, Germany, United Kingdom
MicroPort NeuroTech Co., Ltd.

Recruiting

A PROSPECTIVE, MULTICENTER, SINGLE-ARM TRIAL FOR THE NEW SIZES OF BRIDGE STENTS FOR VERTEBRAL ARTERY STENOSIS: Bridge-MAX

Brain Diseases | Vertebral Artery Stenosis | Vertebral Artery Thrombosis

China
Apellis Pharmaceuticals, Inc.

Recruiting

A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Geographic Atrophy

United States
Cardresearch

Recruiting

A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial (REVIVE)

Chronic Fatigue Syndrome | Long COVID-19 Syndrome

Brazil
University of British Columbia

Recruiting

Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma

Transitional Cell Cancer of the Renal Pelvis and Ureter | Urothelial Carcinoma of the Renal Pelvis and Ureter

Canada
SPP Pharmaclon Ltd.

Recruiting

A Multicenter Clinical Trial of Ingaron in Pulmonary Tuberculosis

Respiratory Tuberculosis

Russian Federation
PT Bio Farma

Recruiting

Effectiveness & Safety of Ovine Enoxaparin Sodium to Originator Enoxaparin in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients: a Multicenter, Non-randomized, Open-label, Non-inferiority Trial

Safety Issues | Effect of Drug

Indonesia
Menarini International Operations Luxembourg SA

Recruiting

Open-label, Multicenter, multinAtionaL, inteRventional Clinical Trial to Assess Efficacy and Safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients (ARTEMISIA)

Hypertension

Hungary
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Trial of ZX-7101A Tablets to Evaluate the Efficacy and Safety in the Treatment of Uncomplicated Influenza in Adolescents (ZX-7101A-207)

Respiratory Viral Infection

China
Monyan Pharmaceutical (Shanghai) Co., Ltd.

Recruiting

A Multicenter Clinical Trial on DH001 Tablets in the Prevention of Doxorubicin-induced Cardiotoxicity in Cancer Patients

Heart Failure | Cancer | Arrhythmia | Doxorubicin Induced Cardiomyopathy | Doxorubicin Adverse Reaction

China
Sigrid Therapeutics AB

Recruiting

Multicenter Trial Investigating Performance and Safety of the Medical Device SiPore21® (SHINE)

Overweight or Obesity

Slovakia, Poland, Romania
Mayo Clinic
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals

Morbidity;Newborn | Death; Neonatal

United States
Mao Jianhua
Tongji Hospital; Xinhua Hospital, Shanghai Jiao Tong University School of Medicine and other collaborators

Recruiting

Study of Adrenocorticotropic Hormone on Children With Frequent Relapse or Steroid-dependent Nephrotic Syndrome: a Prospective, Multicenter, Randomized，Open-label Clinical Trial.

Nephrotic Syndrome in Children

China
Stanford University
Boston Children's Hospital; Duke University

Not yet recruiting

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

Heart Failure | Cardiomyopathies | Congenital Heart Disease | Cardiogenic Shock

United States
Escient Pharmaceuticals, Inc

Recruiting

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria (CALM-CSU)

Chronic Spontaneous Urticaria

Spain, United States, Germany, Canada, Poland, Netherlands
EnCompass Technologies, Inc.

Not yet recruiting

U.S. Multicenter Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

Aortic Stenosis
Duke University

Recruiting

A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial (MOAB)

Recurrent Glioblastoma

United States
University of California, San Diego
National Institute on Drug Abuse (NIDA); RTI International; Drexel University

Recruiting

A Systems Analysis and Improvement Approach for Optimizing HIV Service Delivery in Syringe Services Programs (SAIA-SSP-HIV)

HIV Infections

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia: a Multicenter Open-label Randomized Controlled Trial (DASSOH)

Hyponatremia
University of Campinas, Brazil

Recruiting

Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions A Multicenter Randomized Clinical Trial.

Gingival Recession

Brazil
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Impact of Annual Versus Biannual Infusions of Ocrelizumab in Patients With Active MS,After 2 Years of Initial Treatment, on Freedom From Radiological Disease Activity at Two Years: a Multicenter Randomized Controlled Non-inferiority Trial (WINDOCRE)

Multiple Sclerosis

France
University Hospital, Tours

Not yet recruiting

Health-Economic Evaluation of Early Diagnosis of Epithalial Ovarian Cancer Recurrence Using the ROMA Score: a Prospective Multicenter Randomized Trial (ROMECO)

Epithelial Ovarian Cancer
University of Michigan Rogel Cancer Center

Recruiting

Multicenter Trial of ESK981 in Patients With Select Solid Tumors

Pancreatic Adenocarcinoma | Pancreatic Neuroendocrine Tumor | Pancreatic Neuroendocrine Carcinoma | Adenosquamous Carcinoma | Gastrointestinal Neuroendocrine Tumor | Gastrointestinal Neuroendocrine Carcinoma | Neuroendocrine Prostate Carcinoma

United States
Rush University Medical Center
International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports...

Recruiting

Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)

Meniscus Tear, Tibial

United States
Göteborg University
Forte; Medtanken Group AB; FoU i Västra Götalandsregionen

Recruiting

The Effect and Experience of the Parental Program AFFEKT

Quality of Life | Stress | Parent-Child Relations | Parenting | Behavior, Child

Sweden
Mridula George, MD

Recruiting

OCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-stage Triple-negative Breast Cancer

Triple Negative Breast Cancer (TNBC)

United States
Emory University
CURE Drug Repurposing Collaboratory (CDRC)

Recruiting

Treatment of Long CoronaVirus Disease (COVID) (TLC) Feasibility Trial

COVID-19

United States
Shandong University

Recruiting

High-dose Dexamethasone Plus Hetrombopag vs High-dose Dexamethasone Alone as Frontline Treatment for Newly Diagnosed Adult Primary Immune Thrombocytopenia: A Prospective, Multicenter, Randomized Trial

ITP - Immune Thrombocytopenia

China

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