Search clinical trials for: DCC-2618

Total 250 results

Takeda

Completed

Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI)

Gastroesophageal Reflux

Belgium, Bulgaria, Poland, Estonia, United Kingdom, Czechia
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis (TRuE-AD4)

Atopic Dermatitis

Germany, Poland, United States, Spain, United Kingdom, Italy, Belgium, Canada, Netherlands, Australia, Bulgaria, France, Switzerland, Hungary, Korea, Republic of
Biogen

Enrolling by invitation

A Study to Evaluate the Continuous Safety and Efficacy of Litifilimab (BIIB059) in Adults With Active Systemic Lupus Erythematosus (EMERALD)

Systemic Lupus Erythematosus (SLE)

Spain, Bulgaria, United States, China, Serbia, Mexico, Korea, Republic of, Chile, Argentina, Poland, Japan, Romania, Colombia, Hungary, Czechia, United Kingdom, Taiwan, Philippines, Brazil, Israel, France
Idorsia Pharmaceuticals Ltd.

Recruiting

A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus (OPUS-1)

Lupus Erythematosus, Systemic

Taiwan, United States, Korea, Republic of, Poland, Greece, Philippines, Romania, Bulgaria, Argentina, France, Mexico
Sumitomo Pharma America, Inc.

Terminated

A Clinical Trial to Determine the Long-term Safety and Tolerability of an Investigational Drug in People With Major Depressive Episode Associated With Bipolar I Disorder (Bipolar I Depression).

Depressive Episodes, Bipolar I Depression

United States, Bulgaria, Japan
Organon and Co
Iqvia Pty Ltd

Recruiting

A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain (ELENA)

Endometriosis

United States, Hungary, Poland, France, Germany, Czechia, Belgium, Bulgaria, Italy, Latvia
Seqirus

Active, not recruiting

A Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an Adjuvanted Quadrivalent Influenza Vaccine Compared to a Non-adjuvanted Quadrivalent Influenza Vaccine in Adults ≥65 Years of Age

Influenza, Human

Turkey, Belgium, Bulgaria, Czechia, Finland, Georgia, Italy, Korea, Republic of, Lithuania, Netherlands, Poland, Romania, Spain, Taiwan
Galapagos NV

Recruiting

A Study Evaluating the Effects of GLPG3667 Given as Oral Treatment for up to 24 Weeks in Adults With Dermatomyositis (GALARISSO)

Dermatomyositis

United States, Belgium, Italy, Chile, Spain, Poland, United Kingdom, Bulgaria, Romania, Croatia, Czechia, France, Argentina
Fresenius Kabi SwissBioSim GmbH

Completed

MSB11022 in Moderate to Severe Rheumatoid Arthritis (Auriel-RA)

Moderate to Severe Rheumatoid Arthritis

Bulgaria, United Kingdom, Hungary, Czechia, Poland, Germany
Amgen

Recruiting

Study of Daxdilimab (HZN-7734) in Patients With Moderate-to-Severe Primary Discoid Lupus Erythematosus (RECAST DLE)

Discoid Lupus Erythematosus

United States, Germany, Canada, France, Greece, Denmark, Brazil, Bulgaria, Czechia, Argentina, Poland
Biogen

Recruiting

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus (TOPAZ-1)

Lupus Erythematosus, Systemic

United States, Australia, Korea, Republic of, Chile, Spain, Poland, Philippines, Taiwan, Greece, Brazil, Bulgaria, Mexico, France, Russian Federation, Sweden
Galapagos NV
Gilead Sciences

Completed

Study to Evaluate the Effect of Filgotinib on Semen Parameters in Adult Males With Active Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, or Non-radiographic Axial Spondyloarthritis (MANTA-RAy)

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis | Non-Radiographical Axial Spondyloarthritis

Bulgaria, Ukraine, Poland, Estonia, Czechia, Georgia, Latvia, Spain
H. Lundbeck A/S

Terminated

Study With Lu AF11167 for the Treatment of Negative Symptoms in Patients With Schizophrenia

Schizophrenia

Bulgaria, Czechia, Estonia, Germany, Hungary, Latvia, Poland, Ukraine
H. Lundbeck A/S

Terminated

Efficacy of Lu AF35700 in Patients With Early-in-disease or Late-in-disease Treatment-resistant Schizophrenia (Anew)

Treatment-resistant Schizophrenia

United States, Japan, Russian Federation, Bulgaria, United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

Systemic Lupus Erythematosus

United States, Spain, China, Korea, Republic of, Argentina, Bulgaria, Chile, Greece, Japan, Mauritius, Mexico, Moldova, Republic of, Poland, South Africa, Australia, Colombia, Philippines, Serbia
H. Lundbeck A/S

Completed

Continuation With Vortioxetine in Child and Adolescent Patients With Major Depressive Disorder (MDD) From 7 to 17 Years of Age

Depressive Disorder, Major

Spain, Hungary, Russian Federation, Bulgaria, Estonia, France, Germany, Italy, Latvia, Poland, Serbia, South Africa, United Kingdom
Optinose US Inc.

Completed

Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis Without the Presence of Nasal Polyps

Chronic Rhinosinusitis

United States, Australia, Poland, New Zealand, Spain, Georgia, United Kingdom, Bulgaria, Czechia, Romania
Forest Laboratories

Completed

Study of the Efficacy of a Fixed-dose Regimen of Cariprazine Compared to Placebo for Treatment of the Depressive Episode in Participants With Bipolar I Disorder

Depression | Bipolar Disorder

United States, Bulgaria, Serbia, Ukraine, Croatia, Romania, Puerto Rico, Slovakia
Momenta Pharmaceuticals, Inc.

Completed

Phase 3 Study of M923 and Humira® in Subjects With Chronic Plaque-type Psoriasis

Psoriasis | Chronic Plaque Psoriasis

United States, Poland, Canada, Czechia, Estonia, Germany, Slovakia, Bulgaria, Latvia
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis

NASH

United States, Canada, Spain, Japan, Bulgaria
Hoffmann-La Roche
Atea Pharmaceuticals, Inc.

Terminated

A Six-Month Follow-Up Study of Participants With Coronavirus Disease 2019 (COVID-19) Previously Enrolled in a RO7496998 (AT-527) Study (MEADOWSPRING)

COVID-19 | Long COVID

Denmark, Switzerland, Turkey, Belgium, Mexico, Brazil, Argentina, Germany, Romania, Ukraine
Sumitomo Pharma America, Inc.

Terminated

A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.

Depressive Episodes, Bipolar I Depression

United States, Bulgaria, Japan, Romania, Canada, Slovakia
ALK-Abelló A/S

Completed

Mite Asthma Pediatric Immunotherapy Trial (MAPIT)

Allergic Rhinitis Due to House Dust Mite | Allergic Asthma Due to Dermatophagoides Farinae | Allergic Asthma Due to Dermatophagoides Pteronyssinus

Poland, United Kingdom, Spain, United States, Russian Federation, Hungary, France, Bulgaria, Germany
Pfizer

Suspended

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

COVID-19

United States, United Kingdom, Japan, South Africa, Bulgaria, Puerto Rico, Mexico, Hungary
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW)

Systemic Lupus Erythematosus

United States, Korea, Republic of, Taiwan, Bulgaria, Spain, China, Argentina, Australia, Chile, Greece, Japan, Mauritius, Mexico, Moldova, Republic of, Philippines, Poland, South Africa, Colombia, Brazil, Serbia, Israel, Romania
Novo Nordisk A/S

Active, not recruiting

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes (FOCUS)

Diabetes Mellitus, Type 2

Spain, United States, India, Czechia, Canada, Latvia, United Kingdom, Portugal, Serbia, Poland, Romania, Brazil, Russian Federation, Slovakia, Bulgaria, Mexico, Germany, Greece, Israel
Rigel Pharmaceuticals

Completed

Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis (Taski-2)

Rheumatoid Arthritis

United States, Mexico, Poland, Romania, Colombia, Bulgaria
Novo Nordisk A/S

Active, not recruiting

A Research Study to See How Semaglutide Helps People With Excess Weight and Type 2 Diabetes Lose Weight

Obesity | Diabetes Mellitus, Type 2

United States, Canada, Hungary, Portugal, Slovakia, South Africa, Poland, Bulgaria
Hoffmann-La Roche
Atea Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19 (MORNINGSKY)

COVID-19

Switzerland, Turkey, Denmark, Belgium, Japan, Mexico, Argentina, Brazil, Germany, Portugal, Romania, Ukraine
Forest Laboratories

Completed

Study on the Efficacy, Safety, and Tolerability of Cariprazine Relative to Placebo in Participants With Bipolar I Depression

Depression | Bipolar Disorder

United States, Bulgaria, Poland, Puerto Rico, Lithuania, Estonia
Immunic AG

Active, not recruiting

MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS) (EMPhASIS)

Relapsing-Remitting Multiple Sclerosis (RRMS)

Poland, Bulgaria, Romania, Ukraine
Gedeon Richter Plc.

Completed

Comparative Efficacy and Safety Study of RGB-14-P and Prolia® in Women With Postmenopausal Osteoporosis

Postmenopausal Osteoporosis

Poland, United States, Spain, Hungary, Italy, Czechia, Bulgaria, Ukraine
Pfizer

Completed

Drug Concentration, Immunogenicity, and Efficacy Study in Patients With Rheumatoid Arthritis Currently Treated With Etanercept, Adalimumab, or Infliximab (ANTIBODY-RA)

Rheumatoid Arthritis

United States, Turkey, Bulgaria, Argentina, Australia
Pfizer

Completed

Study of Abrocitinib Compared With Dupilumab in Adults With Moderate to Severe Atopic Dermatitis on Background Topical Therapy

Atopic Dermatitis

Spain, Taiwan, United States, Korea, Republic of, Poland, Canada, Australia, Hungary, Germany, Latvia, Finland, Chile, Bulgaria, Slovakia, Italy
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Safety, Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e., Grand Mal) Seizures.

Generalized Tonic Clonic Seizures

Korea, Republic of, United States, Austria, Serbia, India, Spain, Poland, Malaysia, China, Bulgaria, Denmark, Greece, Hungary, United Kingdom, Belarus, France, Montenegro, Philippines, Romania, Russian Federation, Slovakia, Ukraine, Lebano... and more
Incyte Corporation

Completed

Topical Ruxolitinib Evaluation in Vitiligo Study 1 (TRuE-V1)

Non-segmental Vitiligo

United States, Spain, Canada, France, Poland, Bulgaria, Germany, Italy
Pfizer

Completed

Dose Ranging Study to Assess Efficacy, Safety, Tolerability and Pharmacokinetics of PF-06700841 Topical Cream in Participants With Mild or Moderate Atopic Dermatitis

Atopic Dermatitis

Germany, United States, Canada, Denmark, Hungary, Australia, Latvia, Poland, Bulgaria, Japan
Pfizer

Completed

Study Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis on Background Topical Therapy (JADE Compare)

Skin Diseases | Immune System Diseases | Hypersensitivity | Hypersensitivity, Immediate | Genetic Diseases, Inborn | Skin Diseases, Genetic | Dermatitis | Eczema | Skin Diseases, Eczematous | Dermatitis, Atopic

Spain, Taiwan, United States, Australia, Poland, Germany, Hungary, Bulgaria, Czechia, Japan, Korea, Republic of, Latvia, Canada, United Kingdom, Mexico, Chile, Slovakia, Italy
Fresenius Kabi SwissBioSim GmbH

Completed

A Study to Evaluate the Efficacy, Pharmacodynamics, Safety, and Immunogenicity of FKS518 in Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

Hungary, Poland, Georgia, Bulgaria, Czechia, Estonia
Pfizer

Completed

TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE

Rheumatoid Arthritis

Czechia, Hungary, Spain, Poland, Canada, Bulgaria, Chile, Georgia, Slovakia, Ukraine
Boehringer Ingelheim

Completed

BI 695501 Compared to Adalimumab in Patients With Active Rheumatoid Arthritis

Arthritis, Rheumatoid

Spain, United States, Korea, Republic of, Malaysia, Poland, Thailand, Bulgaria, Chile, Estonia, Germany, Hungary, New Zealand, Russian Federation, Serbia, Ukraine
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN) (TRuE-PN2)

Prurigo Nodularis

Korea, Republic of, Spain, United States, Poland, Italy, Australia, Austria, Germany, Canada, Switzerland, France, Denmark, Bulgaria
Pfizer

Completed

Dose Ranging Study To Assess Efficacy, Safety and Tolerability Of PF-06700841 Topical Cream In Psoriasis

Psoriasis

United States, Germany, Canada, Denmark, Hungary, Australia, Latvia, Poland, Bulgaria, Japan
Biogen

Recruiting

A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy (AMETHYST)

Subacute Cutaneous Lupus Erythematosus | Chronic Cutaneous Lupus Erythematosus

United States, Italy, Korea, Republic of, Taiwan, Argentina, Chile, Spain, Canada, Serbia, France, Germany, Japan, Brazil, United Kingdom, Puerto Rico, Bulgaria, Portugal, Switzerland, Philippines, Saudi Arabia, Sweden, Mexico, Poland, Hunga... and more
Bayer

Completed

A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 52 Weeks in Women Who Have Been Through the Menopause (OASIS-3)

Hot Flashes | Vasomotor Symptoms Associated With Menopause

Belgium, United States, Poland, Spain, Bulgaria, Finland, Canada, Denmark, United Kingdom
Inventiva Pharma

Completed

Phase 2b Study in NASH to Assess IVA337 (NATIVE)

Non-Alcoholic Steatohepatitis (NASH)

United States, Spain, United Kingdom, France, Belgium, Austria, Switzerland, Australia, Germany, Slovenia, Bulgaria, Canada, Czechia, Italy, Mauritius, Poland
Minerva Neurosciences

Completed

A Study to Evaluate the Efficacy and Safety of MIN-117 in Adult Patients With Major Depressive Disorder

Major Depressive Disorder

United States, Bulgaria, Finland, Georgia, Moldova, Republic of, Poland, Ukraine
Sunovion

Completed

Lurasidone Pediatric Bipolar Study (Illuminate)

Bipolar I Depression

United States, Korea, Republic of, Bulgaria, Poland, Mexico, Puerto Rico, Colombia, Hungary, France, Philippines, Ukraine
Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Post-Authorisation Safety Cohort Observation of RetacritTM (Epoetin Zeta) Administered Subcutaneously for the Treatment of Renal Anaemia (PASCO II)

Pregnancy | Lactation | Renal Anemia

France, Croatia, Spain, United Kingdom, Germany, Sweden, Bulgaria, Greece, Denmark, Finland, Ireland, Italy
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Placebo-controlled Safety and Efficacy Study of Pregabalin in Subjects With Post-traumatic Peripheral Neuropathic Pain

Neuropathic Pain

United States, Korea, Republic of, Germany, Hungary, Canada, Denmark, Sweden, Poland, Romania, South Africa, Bulgaria, Croatia, Puerto Rico

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