Search clinical trials for: DDI study

Total 118956 results

Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Eli Lilly and Company

Recruiting

A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants

Healthy

United States
Eccogene

Recruiting

ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants

Type 2 Diabetes Mellitus

United States
Qpex Biopharma, Inc.
Shionogi Inc.; Biomedical Advanced Research and Development Authority

Recruiting

P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants

Bacterial Infections

Australia
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Assess the Effect of Itraconazole Capsules on the Pharmacokinetics of ZX-7101A Tablets in Healthy Adult Subjects in China

Pharmacokinetics

China
Maple Leaf Research

Recruiting

Drug-Drug Interaction Study in Trans Women Living With HIV (T-DDI)

Hiv | Transgenderism

Canada
Yale University
National Institute on Drug Abuse (NIDA); Aptinyx

Recruiting

Safety, Tolerability and Pharmacokinetics of NYX-783 and Oxycodone DDI Study

Opioid Use Disorder

United States
Celgene

Recruiting

A Study Evaluating Potential Disease-Mediated Drug-Drug Interaction in Adult Participants With Active Eosinophilic Esophagitis Receiving Cendakimab

Eosinophilic Esophagitis

United States
Haisco Pharmaceutical Group Co., Ltd.
The Fourth Hospital of Hebei Medical University

Recruiting

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK16149 Capsules and Metformin Hydrochloride Tablets

Diabetic Neuropathies | Diabetic Neuropathy Peripheral

China
Arcus Biosciences, Inc.

Completed

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers (ARC-14)

Healthy Participants

Netherlands
Loxo Oncology, Inc.
Eli Lilly and Company

Completed

A Drug Drug Interaction (DDI) Study of Selpercatinib and Dabigatran in Healthy Participants

Healthy

United States
Jemincare

Completed

A DDI Study of JMKX000623 and Metformin Hydrochloride

Healthy | Drug-Drug Interaction

China
Diagnostica Stago

Active, not recruiting

ThRombosis ExclUsion STudy (TRUST)

Venous Thromboembolism | Pulmonary Embolism | Deep Venous Thromboses

United States, Spain, France, Belgium, Italy
PMV Pharmaceuticals, Inc

Active, not recruiting

A Study to Investigate the Effects of Acid Reducing Agents on Pharmacokinetics of PC14586 in Healthy Participants

Healthy Volunteers

United States
Reata, a wholly owned subsidiary of Biogen
Celerion; Q2 Solutions; Altasciences Company Inc.

Completed

An Open-label DDI Study of Omaveloxolone in Healthy Subjects

Healthy Adult Subjects

United States
Reata, a wholly owned subsidiary of Biogen
Covance

Completed

A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone

Healthy Adult Subjects

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Digoxin (P-Glycoprotein Substrate) in Healthy Participants

Healthy

United States
Eli Lilly and Company

Completed

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Healthy

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Different Formulations of Midazolam in Healthy Participants

Healthy

United States
Melinta Therapeutics, Inc.

Completed

Open Label Study Evaluating the Effects of a Single Oritavancin Infusion on Cytochrome P450 in Healthy Volunteers (DDI)

Healthy

United States
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects

Overweight Subjects | Obese Subjects

China
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Completed

A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy Volunteers

Healthy Volunteers

China
Vigonvita Life Sciences

Completed

Drug-Drug Interaction (DDI) Study for TPN171H

Erectile Dysfunction

China
Haisco Pharmaceutical Group Co., Ltd.

Completed

A Study to Evaluate the DDI of HSK7653 With Metformin

Type 2 Diabetes Mellitus

China
ViiV Healthcare

Completed

Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)

HIV Infections

United States
Yangtze River Pharmaceutical Group Co., Ltd.

Completed

A Study of the Interaction of Tunodafil Hydrochloride Tablets and Alcohol

Erectile Dysfunction

China
Atriva Therapeutics GmbH

Completed

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Food Effect and DDI of Ascending Doses of the MEK Inhibitor Zapnometinib

Healthy

Germany
Drugs for Neglected Diseases

Completed

DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan (OXA-07)

Trypanosomiasis, African

Malaysia
zr Pharma & GmbH

Completed

Pharmacokinetic Drug-Drug Interaction Study of Rucaparib (DDI)

Neoplasms

Poland
Epizyme, Inc.

Completed

Study to Describe the Interaction Between Tazemetostat and Itraconazole and Between Tazemetostat and Rifampin in Participants With Advanced Cancer

Solid Tumor | Mesothelioma | Rhabdoid Tumor | Hematologic Malignancy | Advanced Malignancies | Synovial Sarcoma | Renal Medullary Carcinoma | Diffuse Large B-Cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Non-Hodgkin Lymphoma (NHL) | All Malignancies | Epithelioid Sarcoma (ES)

Spain, United States
Mitsubishi Tanabe Pharma America Inc.

Completed

Relative Bioavailability and Drug-drug Interaction Study With MT-7117 and a Proton Pump Inhibitor (MT-7117 BA DDI)

Healthy Volunteer

Germany
CMP Development, LLC

Completed

Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug)

Drug Drug Interaction

India
Eli Lilly and Company

Completed

A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants

Obesity

United States
Alexion

Completed

Drug-Drug Interaction (DDI) Study of ALXN2050 in Healthy Adult Participants

Healthy

United States
AbbVie

Completed

A Study to Assess the Pharmacokinetics and Safety of Co-administered Oral Galicaftor, Navocaftor, and ABBV-576 in Healthy Adults for the Treatment of Cystic Fibrosis (ABBV-576 DDI)

Healthy Volunteers

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

The DDI Study Had Been Designed to Investigate the Effect of SHR3680 on the Pharmacokinetics of Midazolam, S-Warfarin and Omeprazole

Prostate Cancer Patients

China
Seno Medical Instruments Inc.

Completed

The PIONEER-01 Study of the Imagio Breast Imaging System

Breast Cancer

United States
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz

Malaria

United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Montmorillonite Power or Loperamide on the Pharmacokinetics of Pyrotinib in Healthy Subjects

HER2-positive Recurrent / Metastatic Breast Cancer

China
Altimmune, Inc.

Completed

ALT-801 DDI Study in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

Australia
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Malaria

United Kingdom
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole

Malaria

United Kingdom
Sunshine Lake Pharma Co., Ltd.

Active, not recruiting

A Study to Evaluate Drug-Drug Interaction of Larotinib With Itraconazole and Rifampin in Healthy Adult Participants (Z650)

Healthy Volunteers

China
Hutchmed

Completed

Fruquintinib DDI Study With P-gp and BCRP Substrates

Metastatic Colorectal Cancer

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

DDI Study of Evobrutinib and Carbamazepine

Healthy

Germany
Beijing InnoCare Pharma Tech Co., Ltd.

Completed

DDI Study of Orelabrutinib

Healthy Person

China
Abdul Wali Khan University Mardan

Completed

Drug-Drug Interaction Study of Voriconazole With Clarithromycin.

Healthy

Pakistan
Blade Therapeutics

Completed

Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

Australia
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Blade Therapeutics

Completed

Dedicated Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

United States

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