Search clinical trials for: DNA inflammation

Total 16172 results

LEO Pharma

Not yet recruiting

A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968

Joint Pain | Gout Flares | Joint Inflammation
University Hospital of Ferrara
Azienda Ospedaliera Universitaria Policlinico; Azienda Ospedaliera di Padova; Fondazione IRCCS San Gerardo dei Tintori

Not yet recruiting

Effect of Infections and Global DNA Methylation on Frailty Trajectories in Hospitalized Older Patients (INFRAGEN) (INFRAGEN)

Inflammation | Frailty | Aging | Telomere Shortening | Hospital Infection
Foundation IRCCS San Matteo Hospital
Ministero della Salute, Italy

Recruiting

HCMV Breakthrough Infections During Letermovir Prophylaxis (CMVbreak)

Cytomegalovirus Infections | Hematopoietic Stem Cell Transplantation | Cytomegalovirus Viremia

Italy
Atara Biotherapeutics

Recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

High-grade B-cell Lymphoma | MCL | Diffuse Large B-cell Lymphoma (DLBCL) | Relapsed/Refractory B-cell Non-Hodgkin Lymphoma | DLBCL/High-grade B-cell Lymphoma With MYC and BCL2 Rearrangements | Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma | LBCL With IRF4 Rearrangement | High-grade B-cell... and other conditions

United States
Hamilton Health Sciences Corporation
One Fertility

Not yet recruiting

Supplementation for Male Subfertility (FertEnhancer)

Male Infertility

Canada
Centre Hospitalier Régional d'Orléans

Recruiting

Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS) - Stimulator of Interferon Genes (STING) (ROXANE)

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis

France
Ludwig-Maximilians - University of Munich
University Hospital Erlangen; University Hospital Regensburg

Not yet recruiting

Reduction of SystemiC Inflammation After Ischemic Stroke by Intravenous DNase Administration (ReSCInD) (ReSCInD)

Ischemic Stroke | Inflammatory Response

Germany
Albert Einstein College of Medicine
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Cough Capture as a Portal Into the Lung (CC1)

Lung Diseases | Lung Diseases, Obstructive | Lung Cancer | Lung Diseases, Interstitial | Lung Inflammation

United States
DNA International Hospital
University of Science Ho Chi Minh City

Recruiting

Evaluating the Safety and Efficacy of Autologous Adipose Tissue-derived Mesenchymal Stem Cell Transplantation on Proinflammatory Cytokines and Anti-inflammatory Cytokines on Ageing-related Low-grade Inflammation Patients.

Aging | Chronic Inflammation | Aging Problems

Vietnam
Institute for Atherosclerosis Research, Russia

Not yet recruiting

The Effects of Allicor on Patients After Revascularization Treatment During a Year (TEA-PARTY)

Peripheral Arterial Disease | Atherosclerosis

Russian Federation
Memo Therapeutics AG

Recruiting

Safety, Tolerability and Efficacy of AntiBKV as Treatment of BKV Infection in Kidney Transplant Recipients (SAFE KIDNEY II)

BK Viremia; BKV DNAemia

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLD

Non-alcoholic Fatty Liver Disease | Chronic Hepatitis b

China
The Second Affiliated Hospital of Chongqing Medical...
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

The Efficacy and Safety of Tenofovir Amibufenamide to Treat Low-level Viraemia After Entecavir Treatment (POWER)

Chronic Hepatitis B

China
Olatec Therapeutics LLC

Recruiting

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Arthritis | Joint Pain | Gout | Gout Flare | Gouty Arthritis | Acute Gout Flare | Gout Attack

United States, Spain, France
Children's Hospital Medical Center, Cincinnati

Recruiting

Time-restricted Feeding to Reduce Inflammation in Fanconi Anemia

Fanconi Anemia

United States
Susanne Dam Nielsen, MD, DMSc
Rigshospitalet, Denmark; Technical University of Denmark

Recruiting

Herpesvirus Immunology in Solid Organ Transplant Recipients - Liver Transplant Study (HISTORY)

Varicella Zoster Virus Infection | Cytomegalovirus Infections | Liver Transplant; Complications

Denmark
Ruijin Hospital

Not yet recruiting

Prevalence of Significant Liver Fibrosis and Inflammation in Chronic HBV Infected Patients in Grey Zone

Chronic Hepatitis b
Willows Health
Nottingham Trent University

Not yet recruiting

Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) (BRANCH-P)

Depression | Heart Diseases | Cardiovascular Diseases | HIV Infections | Obesity | Diabetes | Cancer | Chronic Kidney Diseases | Arthritis | Bulimia | Alzheimer Disease | Cellulitis | Cirrhosis | Eczema | Osteoporosis | Appendicitis | Bronchitis | Bowel Disease | Gout | Alcoholic Liver Disease | Flu | High Cholesterol | Allergies | Indigestion | ... and other conditions

United Kingdom
McMaster University
Canadian Institutes of Health Research (CIHR)

Recruiting

Intravenous DNase I for the Treatment of Sepsis (IDEALSepsisI) (IDEALSepsisI)

Sepsis | Critical Illness

Canada
The University of Queensland

Recruiting

A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients (BEAT-BK)

Kidney Transplant Infection | Kidney Transplant Failure and Rejection | BK Viremia

Australia
Fuzhou General Hospital

Recruiting

Peginterferon Alpha-2b Therapy in Chronic Hepatitis Patients With Normal ALT Level and Low Viremia

Chronic Hepatitis B Patients With a Normal ALT Level and Low Viremia

China
University of Vienna
SMZ-Ost Donauspital

Recruiting

DNA Damage and Oxidative Stress in Hospitalized COVID-19 Patients (ABCD)

Covid19

Austria
Ruijin Hospital
Intuitive Surgical

Recruiting

Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors (PORTAL)

Pancreatic Adenocarcinoma | Chronic Pancreatitis | Ampullary Adenocarcinoma | Cholangiocarcinoma, Extrahepatic | Pancreatic Cysts | Pancreatic Endocrine Tumors | Duodenal Adenocarcinoma

China
Peking University People's Hospital

Recruiting

CMV Infection and Immune Intervention After Transplantation

Transplantation Infection | CMV Viremia

China
University of Aarhus
Odense University Hospital; Aarhus University Hospital; Rikshospitalet University...

Recruiting

EVITA Study - Epstein-Barr Virus Infection moniToring in renAl Transplant Recipients (EVITA)

Post-transplant Lymphoproliferative Disorder | EBV Infection | EBV Viremia | Epstein-Barr Virus Associated Lymphoproliferative Disorder

Denmark, Norway
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan Biobank

Inflammation | Sjogren's Syndrome | Dry Eye Syndrome | Healthy Control

Taiwan
Global Healthy Living Foundation
University of Alabama at Birmingham

Recruiting

PatientSpot Formerly Known as ArthritisPower (GHLF)

Heart Failure | Stroke | Epilepsy | Multiple Sclerosis | Obesity | Diabetes | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Peripheral Arterial Disease | Inflammatory Bowel Diseases | Amyotrophic Lateral Sclerosis | Psoriasis | Asthma | Muscular Dystrophy | Fibromyalgia | Alzheimer... and other conditions

United States
University of Wisconsin, Madison
University of Wisconsin Carbone Cancer Center (UWCCC)

Recruiting

Treatment of Cytomegalovirus (CMV) Infections With Viral-Specific T Cells

Cytomegalovirus Infections | Opportunistic Infections | CMV Infection | CMV Viremia

United States
University of Illinois at Chicago
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

DNA Methylation and Vascular Function

Obesity | Vascular Dysfunction

United States
New Discovery LLC

Recruiting

Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission

Viremia | Hepatitis B Infection | Chronic Infection | Birth Defect | Congenital Malformation

China
University of Alabama at Birmingham

Recruiting

Cytomegalovirus (CMV) Vaccines: Reinfection and Antigenic Variation (CMV)

Cmv Congenital | CMV Viremia

Brazil
National Institutes of Health Clinical Center (CC)

Recruiting

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

Healthy Volunteers | Endothelial Dysfunction | Inflammation in Cardiopulmonary and Vascular Disease States

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Eltrombopag for People With Fanconi Anemia

Fanconi Anemia

United States
Martin Huelsmann

Recruiting

NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients

Heart Diseases | Diabetes Mellitus, Type 2

New Zealand, Austria, Netherlands, Spain, United Kingdom
Memorial Sloan Kettering Cancer Center

Recruiting

Trial of Third Party Donor Derived CMVpp65 Specific T-cells for The Treatment of CMV Infection or Persistent CMV Viremia After Allogeneic Hematopoietic Stem Cell Transplantation

CMV Infection | Persistent CMV Viremia

United States
National Institute of Environmental Health Sciences...

Completed

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

Inflammation | Cancer | Cardiomyopathy | HIV-1 Seropositive

United States
Nguyen Ton Ngoc Huynh

Active, not recruiting

Umbilical Cord Mesenchymal Stem Cell for Aging-related Low-grade Inflammation

Diabetes | Lipid Metabolism Disorders | Obese | Aging Problems | Inflammatory Disease

Vietnam
Centre Hospitalier Universitaire de Saint Etienne

Active, not recruiting

Detection of Herpesvirus DNA (CMV, EBV, HHV-6 and HSV) in Colonic Tissue: Impact on Ulcerative Colitis Flare-up (VIRCH)

Colitis, Ulcerative

France
Tulane University
Louisiana Clinical and Translational Science (LA CaTS) Center Clinical Research...

Completed

Epigenetic Analysis of Regulation of the Inflammasome-activating NLRP3 Gene in Monocytes From Atrial Fibrillation Patients and Controls

Atrial Fibrillation | Arrhythmia

United States
Medical University of South Carolina
The Skin Center Dermatology Group

Completed

Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca

Verruca Vulgaris | Molluscum Contagiosum Skin Infection

United States
Hospital do Rim e Hipertensão

Enrolling by invitation

Real-world CMV Outcomes Among Kidney Transplant Recipients in Brazil

CMV Infection | CMV Viremia

Brazil
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

Plasmablastic Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell... and other conditions

United States
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes. (ELICIT)

HIV Infections | Cytomegalovirus | CMV

United States
Carlos Wambier
Brown University; Sun Pharmaceutical Industries Limited; Lifespan; Ocean State...

Active, not recruiting

Effects of Tildrakizumab on Epigenetic Age

Psoriasis | Aging | Inflammation; Skin | Epigenetic Disorder

United States
St Vincent's University Hospital, Ireland
University College Dublin; Health Research Board, Ireland

Completed

Effect of Liraglutide vs CPAP on Cardiometabolic Outcomes in Obstructive Sleep Apnea

Sleep Apnea, Obstructive

Ireland
University of Aarhus
Aarhus University Hospital

Completed

Early Detection of Epstein-Barr Virus Related Disease.

Epstein-Barr Virus Infections | Post-transplant Lymphoproliferative Disorder | Hemophagocytic Lymphohistiocytoses | Epstein-Barr Virus-Related Hodgkin Lymphoma | Epstein-Barr Virus-Related Non-Hodgkin Lymphoma | Mononucleosis | Epstein-Barr Virus Related Malignancy | Epstein-Barr Viraemia | Hemophag...

Denmark
New York Medical College
Merck Sharp & Dohme LLC

Completed

Cytomegalovirus (CMV) Viremia and Disease Occurrence in Pediatric Allogeneic Stem Cell Transplantation Recipients

Cytomegalovirus Infections

United States
Huahui Health

Active, not recruiting

A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level Viremia

Chronic HBV Infection

China
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Beth Israel Deaconess Medical Center
National Institutes of Health (NIH)

Completed

Role of Inflammation in Progressive Multifocal Leukoencephalopathy (PML)

Progressive Multifocal Leukoencephalopathy

United States

Search clinical trials for: DNA inflammation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Trinidad & Tobago

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations