Search clinical trials for: Dose Dense

Total 21002 results

Ottawa Hospital Research Institute

Recruiting

Evaluating Omission of Granulocyte Colony-stimulating Factors in Breast Cancer Patients Receiving Paclitaxel Portion of Dose-dense Adriamycin-cyclophosphamide and Paclitaxel Chemotherapy (REaCT-OGF)

Early-stage Breast Cancer

Canada
Shantou Central Hospital

Recruiting

Neoadjuvant Dose-dense Chemotherapy for HR+/HER2- Breast Cancer Patients With High Proliferation Index

Breast Cancer

China
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Validation of a Treatment Algorithm for Poor-Risk NSGCTnon Seminomatous Germ-cell Tumors (VAPOR)

Non-Seminomatous Germ Cell Tumor

France
Peking University
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Effectiveness of Cryotherapy Combined With Compression Therapy for Preventing Chemotherapy-induced Peripheral Neuropathy

Breast Cancer

China
Centre Georges Francois Leclerc

Recruiting

Evaluation and Modeling of the Effect of G-CSF on the Evolution of Polynuclear Neutrophils During Dense Dose Epirubicin-Cyclophosphamide Regeneration (EMEG-ECDD)

Localized Breast Cancer

France
Georgetown University

Recruiting

RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer (RAGE)

Non-metastatic Breast Cancer | Cancer Related Cognitive Decline

United States
Assistance Publique - Hôpitaux de Paris
BTG International Inc.

Recruiting

Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System Lymphoma (METHOGLU)

Primary Central Nervous System Lymphoma

France
Tongji Hospital
Sun Yat-sen University; First Affiliated Hospital, Sun Yat-Sen University; Qilu... and other collaborators

Not yet recruiting

Biomarker-driven Targeted Therapy in Patients With Recurrent Platinum-resistant Epithelial Ovarian Cancer (BRIGHT)

Ovarian Cancer

China
Second Affiliated Hospital, School of Medicine,...
Women's Hospital School Of Medicine Zhejiang University; Zhejiang Provincial... and other collaborators

Recruiting

Efficacy and Safety of Dose-dense Chemotherapy (ddEC-ddP) for Neoadjuvant Chemotherapy of HER2-negative Breast Cancer

HER2-negative Breast Cancer | Neoadjuvant Chemotherapy

China
Yonggao Mou
The First Affiliated Hospital of Nanchang University

Recruiting

Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimen

Glioblastoma

China
New York Medical College

Recruiting

Dose Dense Rituximab for High Risk Newly Diagnosed Acute Immune Thrombocytopenic Purpura (NYMC207)

Immune Thrombocytopenic Purpura

United States
Fudan University

Recruiting

Carboplatin Intensified Chemotherapy for TRIple NEgative Breast Cancer(CITRINE) (CITRINE)

Triple-negative Breast Cancer

China
Effector Therapeutics

Recruiting

Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies (Zotatifin)

Solid Tumor, Adult

United States
Pusan National University Yangsan Hospital

Recruiting

Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma

Urothelial Carcinoma | Neoadjuvant Chemotherapy | Muscle Invasive Bladder Cancer

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Trial Comparing Dose-dense AC-T With TP as Adjuvant Therapy for TNBC With Homologous Recombination Repair Deficiency

Triple Negative Breast Cancer

China
Kyorin University
Japan Clinical Oncology Group

Recruiting

Bevacizumab Alone Versus Dose-dense Temozolomide Followed by Bevacizumab for Recurrent Glioblastoma, Phase III (RE-GEND)

Recurrence | Glioblastoma | Progression

Japan
Tianjin Medical University Cancer Institute and...

Recruiting

Evaluation of the Relationship of TOP2α Expression and Effect of Non Dose-dense Chemotherapy for Breast Cancer

Breast Cancer

China
Charite University, Berlin, Germany

Not yet recruiting

NeoAdjuvant Chemotherapy Followed by Radical Hysterectomy (OP) Versus Primary Chemo-RADiation in Cervical Cancer FIGO Stage IB2 and IIB (NACOPRAD)

Cervical Cancer
Fudan University

Active, not recruiting

Neoadjuvant Dose-dense EC Followed by ABX With PD-1 for Triple Negative Breast Cancer Patients (NeoTENNIS)

Triple Negative Breast Cancer

China
G1 Therapeutics, Inc.

Completed

Trilaciclib, a CDK4/6 Inhibitor, in Patients With Early-Stage Triple Negative Breast Cancer

Breast Cancer | Triple Negative Breast Cancer

United States
Association Pour La Recherche des Thérapeutiques...

Active, not recruiting

NEoadjuvant Dose-dense MVAC In cOmbination With Durvalumab and Tremelimumab in Muscle-invasive Urothelial Carcinoma (NEMIO)

Infiltrating Bladder Urothelial Carcinoma

France
University Hospital, Saarland

Completed

Dose Dense Chemotherapy in Elderly Patients > 80 Years Old With DLBCL

DLBCL | Old Age; Debility

Germany
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai East Hospital; Zhejiang University; The... and other collaborators

Completed

CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase II (CHABLIS-T II)

Stroke

China
Memorial Sloan Kettering Cancer Center
Genentech, Inc.; Amgen

Completed

Phase II Study of Dose-Dense Doxurubicin and Cyclophosphamide (AC) Followed By Paclitaxel With Trastuzumab in HER2/ NEU-Amplified Breast Cancer: Feasibility

Breast Cancer

United States
Hoffmann-La Roche
Breast International Group; Frontier Science & Technology Research Foundation... and other collaborators

Completed

A Study Comparing Atezolizumab (Anti PD-L1 Antibody) In Combination With Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus Chemotherapy Alone In Patients With Operable Triple-Negative Breast Cancer (IMpassion030)

Triple Negative Breast Cancer

Russian Federation, United States, Israel, Italy, Spain, France, Korea, Republic of, United Kingdom, Denmark, Taiwan, Hungary, Argentina, Australia, Austria, Belgium, Brazil, China, Germany, Hong Kong, Japan, Mexico, Romania, Switze... and more
Icahn School of Medicine at Mount Sinai

Terminated

Neoadjuvant Dose-Dense For Early Her2Neu Positive Breast Cancer

Locally Advanced Breast Cancer

United States
Yale University

Completed

Neoadjuvant MEDI4736 Concomitant With Weekly Nab-paclitaxel and Dose-dense AC for Stage I-III Triple Negative Breast Cancer

Breast Neoplasms

United States
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC

Completed

Dose Dense Paclitaxel With Pembrolizumab (MK-3475) in Platinum Resistant Ovarian Cancer

Ovarian Cancer

United States
Case Comprehensive Cancer Center

Terminated

Weight-based Dosing for Dense Weekly Paclitaxel and Carboplatin in Overweight Patients w/ Body Surface Area (BSA) > 2.0

Gynecologic Malignancies

United States
University of Bergen
Haukeland University Hospital

Active, not recruiting

Predictors for Response to Dose-dense Docetaxel and Epirubicin Breast Cancer (DDP)

Stage III Breast Cancer AJCC V7

Norway
National Cancer Institute (NCI)

Completed

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Glioblastoma | Astrocytoma | Brain Tumor | Gliosarcoma | Astroglioma

United States
Ian E. Krop, MD, PhD
Massachusetts General Hospital; Genentech, Inc.; Brigham and Women's Hospital; New...

Completed

Preoperative Dose-dense Doxorubicin and Cyclophosphamide Followed by Paclitaxel With Bevacizumab in Operable Breast Cancer

Breast Cancer

United States
The Netherlands Cancer Institute

Terminated

Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD

Breast Cancer

Netherlands
Far Eastern Memorial Hospital

Completed

Dose-dense Chemotherapy Versus Intraperitoneal Chemotherapy as First-line Chemotherapy in Advanced Ovarian Cancer

Advanced Ovarian Cancer

Taiwan
AZ-VUB
Universitaire Ziekenhuizen KU Leuven; Universitair Ziekenhuis Brussel

Completed

Phase II Study of Neoadjuvant Weekly Paclitaxel and Carboplatin Followed by Dose Dense Epirubicin and Cyclophosphamide in Stage II and III Triple Negative Breast Cancer

Breast Cancer

Belgium
University of Wisconsin, Madison
Amgen

Completed

Dose Dense TC + Pegfilgrastim Support for Breast Cancer (ddTC)

Female Breast Cancer

United States
Celgene

Completed

Study of Dose-dense Adriamycin Plus Cytoxan (AC) Followed by Either ABI-007 (Abraxane) or Taxol With Bevacizumab as Adjuvant Therapy for Patients With Breast Cancer

Breast Cancer

United States
Memorial Sloan Kettering Cancer Center
New York University; University of North Carolina, Chapel Hill

Completed

Neoadjuvant Dose Dense Gemcitabine and Cisplatin (DD GC) In Patients With Muscle-Invasive Bladder Cancer

Bladder Cancer

United States
Fox Chase Cancer Center

Completed

Dose Dense MVAC for Muscle Invasive Bladder Cancer

Muscle Invasive Bladder Cancer | High Risk Urothelial Carcinoma of the Upper Urinary Tracts

United States
Eisai Inc.

Completed

Dose Dense Doxorubucin and Cyclophosphamide Followed by Eribulin Mesylate for the Adjuvant Treatment of Early Stage Breast Cancer

HER2-normal

United States
Ottawa Hospital Research Institute

Completed

Multicentre Study to Determine the Feasibility of Using an Integrated Consent Model to Compare Three Standard of Care Regimens for The Treatment of Triple-Negative Breast Cancer in the Neoadjuvant/Adjuvant Setting (REaCT-TNBC) (OTT15-04)

Breast Cancer

Canada
National Institutes of Health Clinical Center (CC)
CERN Foundation - Collaborative Ependymoma Research Network

Completed

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

Brain Tumors | Spinal Cord Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Breast Cancer Research Foundation

Completed

Trial of Partial Breast Irradiation With Various Concurrent Chemotherapy Regimens (PBIC)

Breast Cancer

United States
Centre Hospitalier Universitaire de Besancon

Terminated

Preoperative Dose-dense Chemotherapy With Weekly Cisplatin, Epirubicin and Paclitaxel to Treat Patients With Locally Gastric Cancer (IPEC-GC)

Stomach Neoplasms | Oesophageal Junction Cancer | Lower Oesophagus Cancer

France
Yonsei University

Completed

Safety and Efficacy of Pegteograstim in Korean Breast Cancer Patients

Breast Cancer

Korea, Republic of
Agendia
University of South Florida; University of Miami; University of Oklahoma; Ohio... and other collaborators

Completed

MINT I Multi- Institutional Neo-adjuvant Therapy MammaPrint Project I (MINT)

Breast Cancer

United States
Western Regional Medical Center

Terminated

Fasting on Newly Diagnosed Breast Cancer (STEFNE)

HER2-positive Breast Cancer

United States
Memorial Sloan Kettering Cancer Center
Dana-Farber Cancer Institute; Columbia University; Schering-Plough

Completed

Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastoma

Glioblastoma | Gliomas

United States
Fondazione Italiana Linfomi ONLUS

Completed

Dose-dense ABVD First Line Therapy in Early Stage Unfavorable Hodgkin's Lymphoma

Hodgkin Lymphoma

Italy
Beaumont Hospital

Completed

Dose Dense Chemotherapy With Lipegfilgrastim Support in Early Breast Cancer

Breast Cancer

Ireland

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