Search clinical trials for: Drug Drug Interaction Study in Normal Healthy Volunteers

Total 473105 results

Shire

Completed

A Drug Interaction Study of SPD503 and Vyvanse Administered Alone and In Combination in Normal Healthy Volunteers

Healthy

United States
Shire

Completed

A Drug Interaction Study of SPD503 and Concerta Administered Alone and In Combination in Normal Healthy Volunteers

Healthy

United States
Theravance Biopharma

Completed

A Fixed-Sequence, Two-Period, Open-Label Drug-Drug Interaction Study to Assess the Effect of an Inhibitor of Cytochrome P450 Isoenzyme 3A4 and Permeability Glycoprotein 1 on the Pharmacokinetics of TD-1211

Healthy

United States
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Drug Interaction Potentiation

Canada
Ottawa Hospital Research Institute
Merck Sharp & Dohme LLC

Withdrawn

A Drug Interaction Study of Boceprevir in Combination With Amlodipine or Diltiazem in Healthy Volunteers

Hypertension | Hepatitis C

Canada
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Drug Interaction Study of Warfarin and Canagliflozin in Healthy Adult Volunteers

Healthy

Belgium
Allergan
MAP Pharmaceuticals, Inc., a wholly owned subsidiary of Allergan

Completed

Pharmacokinetics & Tolerability Study of MAP0004 Co-administered With Ketoconazole

Healthy

United Kingdom
Boehringer Ingelheim

Completed

Drug-drug Interaction Study of Aggrenox and Omeprazole in Normal Volunteers

Healthy

United States
National Institutes of Health Clinical Center (CC)

Completed

Drug Interaction Study of Tegretol (Carbamazepine) and St. John's Wort in Normal Volunteers

Healthy

United States
Chiesi Farmaceutici S.p.A.

Recruiting

Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers

Chronic Obstructive Pulmonary Disease

Bulgaria
Hangzhou Sciwind Biosciences Co., Ltd.

Recruiting

A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin

Healthy Volunteers

China
Université Catholique de Louvain

Recruiting

Development of Non-invasive Methods to Study Gut Microbiome - Nutrition - Host Interactions

Healthy

Belgium
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
Overseas Pharmaceuticals, Ltd.
Guangzhou Health Start Pharmaceutical Techology Co.,Ltd

Not yet recruiting

An Comparative Pharmacokinetic Study of Amlodipine Besylate Controlled-release Tablets,China in Normal, Healthy, Adult, Human Subjects Under Fasting Conditions

Hypertension

China
Pacira Pharmaceuticals, Inc

Recruiting

Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers

Healthy

United States
Ribon Therapeutics, Inc.

Recruiting

SAD/MAD Safety and PK Study of RBN-3143 in Healthy and Atopic Dermatitis Subjects

Atopic Dermatitis

Australia, New Zealand
Central Institute of Mental Health, Mannheim

Not yet recruiting

Gene-Environment-Interaction: Influence of the COMT Genotype on the Effects of Different Cannabinoids - a PET Study

Healthy Volunteers | Modeling Psychosis

Germany
Arcus Biosciences, Inc.

Completed

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers (ARC-14)

Healthy Participants

Netherlands
National Institute on Drug Abuse (NIDA)
The Peter G. Dodge Foundation (PGDF)

Completed

Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder Via Microbiota Investigations: A Pilot Study

Alcoholism

United States
Takeda

Completed

A Study of the Interaction of Other Drugs With TAK-279 in Healthy Adults

Healthy Volunteers

United States
Daehwa Pharmaceutical Co., Ltd.

Active, not recruiting

Phase 1 Study to Evaluate the Safety and Pharmacokinetic Drug Interaction of DHP2302R1 and DHP2302R2

Healthy Volunteers

Korea, Republic of
Haemonetics Corporation
Machaon Diagnostics; ClinStatDevice

Completed

Normal Reference Range Study With the TEG6s Heparin Neutralization Cartridge in Healthy Volunteers

Healthy

United States
Takeda

Completed

A Study of the Interaction of TAK-279 With Substances That Have an Impact on Metabolism in Healthy Adults

Healthy Volunteers

United States
NewAmsterdam Pharma
Pharma Medica Research, Inc.

Completed

A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and Rosuvastatin

Healthy Volunteers

Canada
Takeda

Completed

A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

United States, Hungary
Eli Lilly and Company

Completed

A Study of Lasmiditan in Healthy Volunteers

Healthy

Singapore
Aligos Therapeutics

Active, not recruiting

A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)

Healthy Volunteers

United States
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Innovative Medicines Initiative; Universitätsklinikum Köln

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Minocin (Minocycline) for Injection in Healthy Adults

Normal Healthy Volunteers

Netherlands
Redx Pharma Plc
Simbec Research

Completed

A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

Liver Diseases | Fibrosis | Kidney Diseases | Inflammation | Idiopathic Pulmonary Fibrosis | Non-alcoholic Steatohepatitis

United Kingdom
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Completed

A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy Volunteers

Healthy Volunteers

China
AbbVie

Completed

A Study to Assess Drug-Drug Interaction Between ABBV-903 and Midazolam in Adult Healthy Volunteers

Healthy Volunteer

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate Drug-drug Interactions and Safety Between "BR3006-1", "BR3006-2", and "BR3006-3" in Healthy Volunteers

Diabetes Mellitus

Korea, Republic of
Dr. Noah Biotech Inc.

Completed

Multiple Dose Study to Evaluate Drug-drug Interactions, Safety and Tolerability of NDC-002 in Healthy Volunteers

Stroke | Stroke Sequelae

Korea, Republic of
DICE Therapeutics, Inc.

Completed

A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants

Healthy Volunteers

United States
Agomab Spain S.L.

Completed

Drug-Drug Interaction Study With AGMB-129 and Midazolam in Healthy Participants

Healthy Volunteers

Belgium
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Healthy Volunteers

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug-drug Interaction of BMS-986196 With Oral Contraceptives in Healthy Female Participants

Healthy Female Volunteers

United States
Hanmi Pharmaceutical Company Limited

Completed

A Study to Evaluate the Drug-drug Interaction and Safety of RLD2301 and RLD2007 in Healthy Volunteers

Healthy Volunteers

Korea, Republic of
Amgen

Completed

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
Sanofi Pasteur, a Sanofi Company
GlaxoSmithKline

Completed

Study of Recombinant Protein Vaccine Formulations Against COVID-19 in Healthy Adults 18 Years of Age and Older

COVID-19 (Healthy Volunteers)

United States
Bayer

Completed

A Study to Learn How Safe the Study Treatment Elinzanetant is and How it Moves Into, Through and Out of the Body When Given as Single Increasing Doses That Are Higher Than Normally Used Compared to Placebo and Moxifloxacin in Healthy Participants

Hot Flashes | Healthy Volunteers | Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men

Germany
Bayer

Completed

Study to Investigate Safety, Tolerability, Pharmacokinetics, and Drug-drug Interaction of Multiple Oral Doses of BAY1830839 in Healthy Male Participants

Healthy Volunteers

Germany
SK Bioscience Co., Ltd.
Coalition for Epidemic Preparedness Innovations

Completed

Safety and Immunogenicity Study of SARS-CoV-2 Nanoparticle Vaccine (GBP510) Adjuvanted With Aluminum Hydroxide (COVID-19)

COVID-19 (Healthy Volunteers)

Korea, Republic of
Takeda

Completed

Study to Investigate the Safety and Immunogenicity of a Tetravalent Chimeric Dengue Vaccine in Healthy Volunteers Between the Ages of 1.5 - 45 Years

Healthy

Colombia, Singapore, Thailand, Puerto Rico
MODAG GmbH
Teva Pharmaceutical Industries, Ltd.; Quotient Sciences; Aptuit

Completed

A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)

Healthy Volunteers

United Kingdom
Global Antibiotics Research and Development Partnership
Parexel; KCAS

Completed

Zoliflodacin Bioequivalence and Drug-Drug Interaction Study

Healthy Volunteers

Germany
Jiangsu Simcere Pharmaceutical Co., Ltd.

Completed

Drug-Drug Interaction Study of Itraconazole, Rifampicin and Midazolam With SIM0417/Ritonavir in Healthy Participants

Healthy Volunteers

China

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