Search clinical trials for: Drug-drug Interactions

Total 950 results

AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Cairo University

Recruiting

Drug-drug Interactions With Anti-tuberculous Drugs

Drug-drug Interaction

Egypt
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SY-5007 in Healthy Subjects

Healthy Subjects

China
Daewoong Pharmaceutical Co. LTD.

Recruiting

Drug-drug Interactions Between DWC202313 and DWC202314 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Dizal Pharmaceuticals

Recruiting

Drug-drug Interactions Between AZD4205 and Itraconazole/Carbamazepine

Healthy Subjects

United States
Celgene

Recruiting

A Study Evaluating Potential Disease-Mediated Drug-Drug Interaction in Adult Participants With Active Eosinophilic Esophagitis Receiving Cendakimab

Eosinophilic Esophagitis

United States
University Hospital, Bordeaux

Recruiting

Impact of an Artificial Intelligence Platform on Inappropriate Medication Use in Older Adults (PING)

Drug-drug Interactions | Geriatric Disease

France
University of Alabama at Birmingham
Merck Sharp & Dohme LLC; University of Washington; Wits Reproductive Health and...

Active, not recruiting

Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa (EPIC)

HIV Infections | Contraception | Drug-drug Interaction

South Africa
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Dizal Pharmaceuticals

Completed

Drug-drug Interactions Between DZD9008 and Itraconazole/Carbamazepine

Healthy Subjects

United States
Daewoong Pharmaceutical Co. LTD.

Completed

Drug-drug Interactions Between DWP14012 and Aspirin in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Enrolling by invitation

Drug-drug Interactions Between DWC202211 and DWC202212 in Healthy Subjects (DWJ1610)

Drug-drug Interaction

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Completed

Drug-drug Interactions Between DWP14012 and DWC202202 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Onconic Therapeutics Inc.

Completed

Drug-drug Interactions and Safety Among JP-1366, Amoxicillin, and Clarithromycin in Healthy Volunteers

Helicobacter Pylori Associated Gastrointestinal Disease

Korea, Republic of
Shionogi

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy Adults

Healthy Volunteer

United States, Japan
Eisai Co., Ltd.

Completed

A Study to Assess the Effect of Food Intake and Drug-drug Interactions of E7090 When Co-administered With Rabeprazole or Rifampin in Healthy Participants

Healthy Participants

Japan
Makerere University
University of Turin, Italy; University of Liverpool; European and Developing...

Completed

Drug-drug Interactions Between Remdesivir and Commonly Used Antiretroviral Therapy (RemTLAR)

HIV/AIDS | Ebola

Uganda
Acerta Pharma BV

Completed

A Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics, Food Effects, and Drug-drug Interactions of ACP-196 in Healthy Participants

Healthy Participants

United States
Pfizer

Completed

Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600

Healthy Volunteers

Belgium
Pfizer

Completed

A STUDY TO EVALUATE THE EFFECT OF PF-06651600 ON PHARMACOKINETICS OF SINGLE DOSE SUMATRIPTAN IN HEALTHY PARTICIPANTS.

Healthy Volunteers

United States
Centre Hospitalier Universitaire Vaudois

Completed

Drug-drug Interactions Between Antiretroviral Drugs and Cardiovascular Drugs in Elderly Patients

Cardiovascular Diseases | HIV Infections | Drug Interactions

Switzerland
AstraZeneca
Parexel

Completed

A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine

Solid Tumours

United States
Walter K. Kraft
Merck Sharp & Dohme LLC

Completed

Doravirine, Rifapentine and Isoniazid Interaction (DORIIS)

Latent Tuberculosis | Human Immunodeficiency Virus | Drug Interaction Potentiation | Rifamycins Causing Adverse Effects in Therapeutic Use

United States
Muğla Sıtkı Koçman University

Unknown

Epidemiology of Polipharmacy and Potential Drug-Drug Interactions in Elderly Cardiac Outpatients (EPIC)

Polypharmacy | Drug-drug Interactions

Turkey
Bayer

Completed

Study to Learn More About the Effect of Itraconazole (ITZ) Given Repeatedly by Mouth on the Way How the Study Drug BAY1902607 Given One Time by Mouth Acts in the Human Body of Healthy Male Participants

Drug Interactions

Germany
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer

Prostate Cancer | Pharmacokinetics of Dextromethorphan | Pharmacokinetics of Caffeine

Moldova, Republic of
Genelex Corporation
University of Utah

Completed

YouScript IMPACT Registry (IMPACT)

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme Deficiency | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome... and other conditions

United States
Genelex Corporation

Completed

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome P450 CYP2C9 Enzyme Deficiency | Cytochrome P450 CYP2C19 Enzyme Deficiency | Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant | CYP2D6 Polymorphism | Ultrarapid... and other conditions

United States
Johnson & Johnson Pharmaceutical Research & Development...

Withdrawn

A Study to Evaluate the Pharmacokinetic Drug Interaction Between Multiple Doses of JNJ-31001074 and a Single Dose of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Women

Healthy | Pharmacokinetics | Drug Interactions
Bristol-Myers Squibb

Completed

A Phase 1 Drug-drug Interaction Study in Healthy Volunteers (DDI)

Drug-drug Interaction Study

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
AstraZeneca

Completed

Study in Healthy Volunteers to Investigate the Effects of Ketoconazole on the Pharmacokinetics of NKTR-118

Healthy Volunteers | Bioavailability | Drug- Drug Interactions

United States
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
Repros Therapeutics Inc.

Completed

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

Drug-drug Interaction

United States
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Losartan and PA21

Drug Interaction Potentiation

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Abiraterone Following Administration of Abiraterone Acetate Tablets in Healthy Adult Men

Healthy Volunteers

Belgium
The Miriam Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Unknown

Rifampin and Efavirenz Interactions in Older Children

HIV | Tuberculosis

Ghana
The Miriam Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Unknown

Rifampin and Nevirapine Interactions in Young Children

HIV | Tuberculosis

Ghana
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Warfarin and PA21

Drug Interaction Potentiation

United States
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Digoxin and PA21

Drug Interaction Potentiation

United States
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Completed

Drug-drug Interaction Study in Healthy Male Volunteers Following the Administration of Pantoprazole and Rosuvastatin

Drug Interaction Potentiation

Canada
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Omeprazole and PA21

Healthy

United States
Vifor Pharma

Completed

A Drug-Drug Interaction Study of Furosemide and PA21

Healthy

United States
University of North Carolina, Chapel Hill
Humana Foundation

Not yet recruiting

Food and Friends: Healthy Meals Delivered to You

Food Insecurity | Mental Health Issue
University of Alberta

Not yet recruiting

Hemispheric Asymmetries in Emotion-Cognition Interactions

Anxiety Depression Disorder
Chiesi Farmaceutici S.p.A.

Recruiting

Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers

Chronic Obstructive Pulmonary Disease

Bulgaria
Atea Pharmaceuticals, Inc.

Not yet recruiting

Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir

Healthy Volunteer Study

Canada
University of Copenhagen
LEGO Foundation

Recruiting

The Playful Learning in Infancy Program (PLIP)

Parent-Child Relations | Infant Development

Denmark

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