Search clinical trials for: Drug-drug interaction

Total 2878 results

AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Chiesi Farmaceutici S.p.A.

Recruiting

Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers

Chronic Obstructive Pulmonary Disease

Bulgaria
Cairo University

Recruiting

Drug-drug Interactions With Anti-tuberculous Drugs

Drug-drug Interaction

Egypt
Atea Pharmaceuticals, Inc.

Not yet recruiting

Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir

Healthy Volunteer Study

Canada
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Drug-drug Interaction Study of HRS-1780 Tablets in Healthy Subjects

Chronic Kidney Disease(CKD)

China
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SY-5007 in Healthy Subjects

Healthy Subjects

China
Daewoong Pharmaceutical Co. LTD.

Recruiting

Drug-drug Interactions Between DWC202313 and DWC202314 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

Drug-drug Interaction Study of XZP-3621 Tablet

Healthy Subjects

China
Dizal Pharmaceuticals

Recruiting

Drug-drug Interactions Between AZD4205 and Itraconazole/Carbamazepine

Healthy Subjects

United States
Radboud University Medical Center
Astellas Pharma Inc

Recruiting

Determining the Clinical Relevance of the Interaction Between Enzalutamide and the Opioid Morphine and the DOAC Edoxaban (MIND THE GAP)

Drug-drug Interaction

Netherlands
Tomsk National Research Medical Center of the Russian...

Recruiting

PIM Incidence in Older Cardiovascular Patients During COVID-19 Pandemics (PIM-BARS)

Potentially Inappropriate Medications

Russian Federation
Celgene

Recruiting

A Study Evaluating Potential Disease-Mediated Drug-Drug Interaction in Adult Participants With Active Eosinophilic Esophagitis Receiving Cendakimab

Eosinophilic Esophagitis

United States
University of Alabama at Birmingham
National Institute of Allergy and Infectious Diseases (NIAID); Indiana University and other collaborators

Recruiting

Kuwa Free! - Live Free!

HIV Infections | Contraception | Drug-drug Interaction

Kenya
University Hospital, Bordeaux

Recruiting

Impact of an Artificial Intelligence Platform on Inappropriate Medication Use in Older Adults (PING)

Drug-drug Interactions | Geriatric Disease

France
AstraZeneca

Terminated

Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies

Haematological Malignancies

France, Italy, United States, Korea, Republic of, Germany, Australia
Alexion Pharmaceuticals, Inc.

Completed

Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine

Healthy Participants

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

Drug-drug Interaction Study of Lemborexant as an Adjunctive Treatment for Buprenorphine/Naloxone for Opioid Use Disorder

Opioid Use Disorder | Drug Interaction | Analgesics

United States
University of Alabama at Birmingham
Merck Sharp & Dohme LLC; University of Washington; Wits Reproductive Health and...

Active, not recruiting

Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa (EPIC)

HIV Infections | Contraception | Drug-drug Interaction

South Africa
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
Kaken Pharmaceutical

Active, not recruiting

A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants

Healthy Adults

United States
Boehringer Ingelheim

Completed

Drug-drug Interaction Trial Between Rifampicin and BI 409306 in Healthy Volunteers

Healthy

Germany
AstraZeneca
Parexel

Terminated

A Study to Assess the Effect of AZD5055 on the Pharmacokinetics (PK) of Nintedanib in Healthy Participants.

Healthy Subjects

United Kingdom
Arcus Biosciences, Inc.

Completed

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers (ARC-14)

Healthy Participants

Netherlands
AstraZeneca

Active, not recruiting

Drug-drug Interaction Study With AZD5305 and Itraconazole in Patients With Advanced Solid Malignancies

Advanced Solid Malignancies

Romania, Moldova, Republic of
DICE Therapeutics, Inc., a wholly owned subsidiary...

Completed

A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants

Healthy Participants

United States
Insel Gruppe AG, University Hospital Bern
University of Bern; Center for Primary Care and Public Health (Unisante), University...

Enrolling by invitation

B-free Multistage Trial (B-free)

HIV | Drug Resistance | Drug Drug Interaction

Switzerland
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Boehringer Ingelheim

Completed

Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin

Healthy

Germany
Pfizer

Completed

Drug-Drug Interaction Study Assessing Effect of Carbamazepine on PF-07321332 Boosted With Ritonavir

Healthy Participant

United States
Pfizer

Completed

Drug-Drug Interaction Study to Estimate the Effect of PF-07321332/Ritonavir and Ritonavir on Midazolam in Healthy Participants

Healthy Participants

Belgium
University of Cape Town
Wellcome Trust; Medecins Sans Frontieres, Netherlands

Completed

Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosis (RADIANT-TB)

HIV Infections | Tuberculosis

South Africa
AstraZeneca
Parexel

Completed

A Study to Assess the Effects of Fluvoxamine on Savolitinib Exposure in Healthy Male Subjects

Healthy Male Subjects

United States
ViiV Healthcare

Completed

Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)

HIV Infections

United States
Bristol-Myers Squibb

Completed

A Study to Investigate the Interaction of BMS-986322 and a Combined Oral Hormonal Contraceptive (Ethinyl Estradiol [EE]/Norethindrone [NET]) in Healthy Female Participants

Healthy Participants

United States
Daiichi Sankyo, Inc.

Completed

A Study of Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment

Hepatic Impairment | Moderate Impaired Hepatic Function

United States
SIGA Technologies
PPD; Biomedical Advanced Research and Development Authority

Completed

Drug-drug Interaction Study of TPOXX When Co-administered With Phosphate Binders

Smallpox

United States
Pfizer

Completed

Drug-Drug Interaction Study Assessing Effect of Itraconazole on PF-07321332/Ritonavir in Healthy Participants

Healthy Participant

Belgium
GlaxoSmithKline

Suspended

Drug Interaction Assessment of GSK3882347 in Healthy Participants Aged 18 to 65 Years

Urinary Tract Infections

United Kingdom
ViiV Healthcare

Completed

First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4011499 in Healthy Participants

HIV Infections

United States
Dizal Pharmaceuticals

Completed

Drug-drug Interactions Between DZD9008 and Itraconazole/Carbamazepine

Healthy Subjects

United States
zr Pharma & GmbH

Completed

Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives

Neoplasms

Poland, Slovakia, Hungary
Atea Pharmaceuticals, Inc.

Completed

Drug-drug Interaction Study of Ruzasvir and Bemnifosbuvir (AT-527)

Healthy Volunteer Study

Canada
AstraZeneca

Completed

A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.

Dyslipidemia

United States
CMP Development, LLC

Completed

Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug)

Drug Drug Interaction

India
Alexion

Completed

Potential Drug Interaction Between ALXN2040 and Rosuvastatin

Healthy Participants

United States
Daewoong Pharmaceutical Co. LTD.

Completed

Drug-drug Interactions Between DWP14012 and Aspirin in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Enrolling by invitation

Drug-drug Interactions Between DWC202211 and DWC202212 in Healthy Subjects (DWJ1610)

Drug-drug Interaction

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Completed

Drug-drug Interactions Between DWP14012 and DWC202202 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
MODAG GmbH
Teva Pharmaceutical Industries, Ltd.; Quotient Sciences; Aptuit

Completed

A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)

Healthy Volunteers

United Kingdom
Jiangsu Simcere Pharmaceutical Co., Ltd.

Completed

Drug-Drug Interaction Study of Itraconazole, Rifampicin and Midazolam With SIM0417/Ritonavir in Healthy Participants

Healthy Volunteers

China

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