Search clinical trials for: Dual PI3K/mTOR Inhibitor

Total 69240 results

Pfizer

Terminated

A Study Of Two Dual PI3K/mTOR Inhibitors, PF-04691502 And PF-05212384 In Patients With Recurrent Endometrial Cancer

Endometrial Neoplasms

United States, Canada, Spain, United Kingdom, Japan, Russian Federation, Poland, Australia
Beijing Tiantan Hospital

Recruiting

Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅳ(TRACE Ⅳ)

Minor Ischemic Stroke | Tenecteplase

China
University of Alabama at Birmingham

Not yet recruiting

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

Non Small Cell Lung Cancer

United States
Kaohsiung Medical University

Recruiting

Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp Eradication

Helicobacter Pylori Eradication

Taiwan
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Tegoprazan Dual Therapy and Furazolidone-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication: A Prospective, Multicenter, Open-label, Randomized Controlled Clinical Study

Helicobacter Pylori Infection | Tegoprazan | Furazolidone
Shenyang Northern Hospital

Not yet recruiting

OCT or Angiography Guided De-escalation of DAPT

ST Elevation Myocardial Infarction | Dual Antiplatelet Therapy | Optical Coherence Tomography | Antiplatelet De-escalation | Neointimal Coverage

China
ANRS, Emerging Infectious Diseases

Not yet recruiting

Study Evaluating the Safety, in Terms of HBV Virological Control at 96 Weeks, of 2 Antiviral Treatment Relief Strategies, in Patients Co-infected With the HIV-1 and HBV Viruses (BI-LIGHT)

HIV Infections | HBV Coinfection
BioNTech SE
DualityBio Inc.

Not yet recruiting

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Endometrial Cancer
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections (LUCY-1)

Cytomegalovirus Infection

France
AstraZeneca

Recruiting

Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

China
University College, London
Novartis; Cancer Research UK; Janssen Pharmaceutica NV

Not yet recruiting

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer (STAMPEDE2)

Prostate Cancer Metastatic
Beijing Tiantan Hospital

Not yet recruiting

Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke (TAPIS)

Ischemic Stroke, Acute
Chen Xiaoping

Recruiting

Triple vs. Dual Adjuvant Therapy Following Liver Resection for HCC.

HCC

China
Tongji University

Recruiting

Pembrolizumab Combined With Preoperative Chemotherapy (Albumin Paclitaxel+Carboplatin) Neoadjuvant Therapy for Resectable Locally Advanced (Stage II/III) Esophageal Squamous Cell Carcinoma

Esophageal Cancer

China
The Fourth Affiliated Hospital of China Medical...

Recruiting

A Prospective, Experimental, Multicenter, Open-label, Randomized, Controlled Trial of 3-month Dual Antiplatelet Therapy Followed by Ticagrelor Versus 6-month Dual Antiplatelet Therapy Followed by Ticagrelor After Implanting Bridge

Brain Disease | Vertebral Artery Stenosis

China
Woo-Keun Seo

Not yet recruiting

Highest Efficacy of Dual Antiplatelet Therapy After Carotid Artery Stenting in High Bleeding Risk Patients

Carotid Artery Diseases
Medical University of Warsaw

Recruiting

Aspirin Dose Comparison in Elderly PCI Patients: 30mg vs. 75mg in Acute Coronary Syndrome (LowASA-PCI)

Myocardial Infarction | Acute Coronary Syndrome

Poland
Samsung Medical Center

Recruiting

Emulation of Randomized Clinical Trial in Cardiovascular Disease (RCT-BigData)

Myocardial Infarction | Coronary Artery Disease

Korea, Republic of
Shenyang Northern Hospital

Not yet recruiting

OPT-CAD Score GUIded Dual ANtiplatelet De-esCalation Time (OPT-GUIDNACE)

Acute Coronary Syndrome

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Antiplatelet Therapy After Successful Percutaneous Coronary Intervention for Chronically Occluded Coronary Artery (DAPT-CTO)

Chronic Total Occlusion
Xijing Hospital of Digestive Diseases

Recruiting

Standard or Short-course Vonoprazan Non-bismuth Triple Therapy or High-dose Dual Therapy Versus Rabeprazole-bismuth Quadruple Therapy for Primary Helicobacter Pylori Eradication

the Eradication Rates of Helicobacter Pylori

China
Yongquan Shi

Recruiting

Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Gastritis Dyspepsia Helicobacter Pylori Infection Gastric Cancer Peptic Ulcer

China
Fu Jen Catholic University Hospital

Recruiting

Fourteen-Day Vonoprazan-Based Dual Therapy With Amoxicillin as First-Line Helicobacter Pylori Treatment in Comparison With Extended Sequential Therapy

Helicobacter Pylori Infection

Taiwan
Jeil Pharmaceutical Co., Ltd.

Not yet recruiting

Evaluation of Efficacy and Safety When Administered JP-2266 in Type 2 Diabetes Patients

Type 2 Diabetes Mellitus

Korea, Republic of
Yuhan Corporation

Not yet recruiting

Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension

Essential Hypertension

Korea, Republic of
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Stent-Assisted Coiling Followed by Ticagrelor Monotherapy Instead of Dual Antiplatelet Therapy in Unruptured Intracranial Aneurysm (SAC-TIDE)

Intracranial Aneurysm | Stent Complication

China
China National Center for Cardiovascular Diseases

Not yet recruiting

24 Versus 12-Month Dual Antiplatelet Therapy After Drug-Eluting Stent in Patients With Elevated Lipoprotein(a) Levels (DAPT-Lp(a))

Coronary Artery Disease | Dual Antiplatelet Therapy | Elevated Lipoprotein(a) Level | Drug-Eluting Stent

China
OCEAN-SHD Study Group

Recruiting

Non-antithrombotic Therapy After Transcatheter Aortic Valve Implantation Trial

Aortic Stenosis | Aspirin | TAVI(Transcatheter Aortic Valve Implantation) | DAPT(Dual Antiplatelet Therapy) | SAPT(Single Antiplatelet Therapy)

Japan
Shanghai Changzheng Hospital

Not yet recruiting

The Observation on the Efficacy of Dual Therapy Based on Vonoprazan in Eradicating Helicobacter Pylori

The Eradication Rate of Helicobacter Pylori
iVascular S.L.U.

Not yet recruiting

Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy (ANGIODAPT)

Coronary Artery Disease
Azienda Ospedaliera Universitaria Policlinico "G...
Gianluca Di Bella; Antonio Micari; Giampiero Vizzari; Giorgio Quadri; Greca Zanda; Ferdinando...

Recruiting

De-escalating Antiplatelet Therapy to Assess Platelet Reactivity and Outcomes in High Bleeding Risk Patients With Recent ACS (DESC-HBR)

Coronary Artery Disease | Acute Coronary Syndrome | Dual Antiplatelet Therapy

Italy
Riphah International University

Recruiting

the Effect of Speed Dependent Treadmill Training on Dual Task Performance in Patient With Parkinson's Disease.

Parkinson Disease

Pakistan
Xueli Cai

Recruiting

Stent Implantation Versus Balloon Dilation for Acute Anterior Circulation Tandem Occlusion (START)

Stroke | Thrombectomy | Tandem Occlusion

China
Fudan University

Recruiting

Cryoablation Combined With Tislelizumab Plus Lenvatinib in 1L Treatment of Advanced HCC (CASTLE-10) (CASTLE-10)

Hepatocellular Carcinoma

China
Fudan University

Recruiting

Cryoablation Combined With Tislelizumab Plus Lenvatinib In Previously Treated Gastric Cancer Liver Metastasis (CASTLE-09) (CASTLE-09)

Gastric Cancer Metastatic to Liver

China
Xuanwu Hospital, Beijing

Recruiting

Drug-eluting Stenting Versus Medical Treatment for Extracranial Vertebral Artery Stenosis (VISTA)

Ischemic Stroke | Vertebral Artery Stenosis

China
Yanqing Li
The Affiliated Hospital of Qingdao University; The Second Affiliated Hospital... and other collaborators

Recruiting

Comparison of Two Dual Therapies in the First-line Treatment of Helicobacter Pylori Infection （SHARE2301）

Helicobacter Pylori Infection

China
Fudan University

Recruiting

Oncolytic Virotherapy Combined With Tislelizumab Plus Lenvatinib in Patients With Advanced Biliary Tract Cancer (OPTIONS-05) (OPTIONS-05)

Advanced Biliary Tract Cancer

China
Centro Cardiologico Monzino
IRCCS National Neurological Institute "C. Mondino" Foundation

Recruiting

Antiplatelet Therapies in Patients With Depression and Coronary Disease (ENHANCE)

Depression | Coronary Artery Disease

Italy
Daejeon St. Mary's hospital
Jeil Pharmaceutical Co., Ltd.

Not yet recruiting

The Efficacy and Safty of Proton Pump Inhibitor (Lansoprazole) (PPI)

Coronary Artery Disease
Kiyuk Chang
Seoul St. Mary's Hospital; Korea University Guro Hospital; St Vincent's Hospital and other collaborators

Recruiting

Comparison of 1 Month vs. 12 Months DAPT in Patients Undergoing PCI With Genoss® DES (GENOSS-DAPT)

Coronary Artery Disease

Korea, Republic of
Hospital Israelita Albert Einstein

Recruiting

Platelet Sub-study of the Neomindset Trial

Acute Coronary Syndrome

Brazil
University Hospital, Clermont-Ferrand
Fondation Apicil; Inserm U1107 " Neuro-Dol ", Clermont-Ferrand, France; Plateforme... and other collaborators

Not yet recruiting

Helping Osteoarthritis Patients to Walk With NSAID (PERIPATEI)

Chronic Pain | Osteoarthritis, Knee | Osteoarthritis, Hip

France
Second Affiliated Hospital, School of Medicine,...

Recruiting

Exploratory Observation of Two Short-term Regimens After LAA Occlusion by LAMax LAAC® Device for Subjects With Non-valvular Atrial Fibrillation

Non-valvular Atrial Fibrillation

China
Xijing Hospital of Digestive Diseases

Recruiting

Effects of High-dose Dual Therapy and Bismuth Quadruple Therapy for Helicobacter Pylori Eradication on Intestinal Microecology

Gastritis | Dyspepsia | Gastric Cancer | Peptic Ulcer | Helicobacter Pylori Infection

China
Emory University
National Cancer Institute (NCI); Xencor, Inc.

Recruiting

Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer

Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma | Castration-Sensitive Prostate Carcinoma

United States
Insel Gruppe AG, University Hospital Bern

Recruiting

Algorithm-based Tailoring of Dual Antiplatelet Therapy to Improve Outcomes Following Percutaneous Coronary Interventions (TAILOR-DAPT)

Coronary Artery Disease | Percutaneous Coronary Intervention | Platelet Aggregation Inhibitors

Switzerland
Kindai University
Boston Scientific Corporation

Recruiting

PRasugrEl Monotherapy Following prImary percUtaneous Coronary Intervention for ST-elevation Myocardial Infarction (PREMIUM)

ST-segment Elevation Myocardial Infarction (STEMI)

Japan
University of Florida

Recruiting

Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI (TAILOR BLEED)

Coronary Artery Disease

United States

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