Search clinical trials for: Endothelial Function, MRI, Vascular Biology

Total 47085 results

Rio de Janeiro State University
Laboratory for Clinical and Experimental Research on Vascular Biology

Completed

Effect of L-arginine on Microcirculation, Myogenesis and Angiogenesis Associated With Aging, Sarcopenia and Diabetes

Type 2 Diabetes | Sarcopenia | Aging | Microcirculation

Brazil
Pär Johansson

Terminated

Metabolomic Alterations in the Vascular Compartment in Patients With Sepsis (METSEP)

Endothelial Dysfunction

Denmark
Boston University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Resveratrol on Endothelial Function in Type 2 Diabetes Mellitus

Diabetes Mellitus

United States
Rio de Janeiro State University
Laboratory for Clinical and Experimental Research on Vascular Biology

Completed

Acute and Short-term Chronic Effects of Galvus (Vildagliptin) in Diabetes Type 2 Obese Women

1- Microvascular Function | 2-oxidative Stress | 3-inflammation

Brazil
Rio de Janeiro State University
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Completed

Effect of Resistance Training on Microvascular, Hemodynamic and Physical Parameters in Obese Adolescents

Obesity

Brazil
University of Calgary

Completed

Endothelial Function Assessed With BOLD-MRI (EFBOLD-MRI)

Endothelial Function

Canada
Eastman Dental Insitute and Hospital
University College London Hospitals; Johnson & Johnson; British Heart Foundation and other collaborators

Completed

Effect of Intensive Periodontal Therapy on Vascular Function

Periodontitis

United Kingdom
Hospital Universitario Getafe

Recruiting

Biomarkers of Inflammation and Endothelial Dysfunction in Patients With Myocardial Infarction With Non-obstructive Coronary Arteries (IMACORN-INFLI)

Myocardial Infarction | Inflammation | Biomarkers | Endothelial Dysfunction | MINOCA

Spain
S. Tony Wolf

Not yet recruiting

Effects of an Antioxidant Supplement on Blood Vessel Health

Healthy
VA Office of Research and Development

Not yet recruiting

NightWare and Cardiovascular Health in Veterans With PTSD

Cardiovascular Diseases | Endothelial Dysfunction | Vascular Stiffness | Nightmare | Autonomic Dysfunction | Post-traumatic Stress Disorder (PTSD) | Veteran

United States
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions
Maastricht University Medical Center
Diabetes Fonds

Recruiting

The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 Diabetes (PYRAMID)

Type 2 Diabetes | Neuropathy, Diabetic | Nephropathy, Diabetic | Microvascular Function | Retinopathy, Diabetic

Netherlands
Allife Medical Science and Technology Co., Ltd.
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Critical Limb Ischemia

Critical Limb Ischemia

China
Eva Rumiz González
Hospital Clinic of Barcelona; Hospital General Universitario Elche; Hospital... and other collaborators

Recruiting

INOCA Spanish National Registry (ESP-INOCA)

Ischemia | Coronary Disease | Non-Obstructive Coronary Atherosclerosis

Spain
Josip Juraj Strossmayer University of Osijek
University Hospital Center Osijek

Not yet recruiting

Endothelial Function in Prehypertension

Hypertension,Essential

Croatia
Zhongshan Ophthalmic Center, Sun Yat-sen University

Not yet recruiting

Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage (DR)

Diabetic Retinopathy | Diabetic Macular Edema | Anti-vascular Endothelial Growth Factor

China
Kodiak Sciences Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR) (GLOW2)

Non-proliferative Diabetic Retinopathy

United States, Puerto Rico
University of Colorado, Denver
National Institute on Aging (NIA)

Not yet recruiting

Cardiometabolic Consequences of the Loss of Ovarian Function (LILAC)

Menopause | Aging | Adiposity | Estrogen Deficiency

United States
Fundación EPIC

Recruiting

Plan to Evaluate Early Endothelialization of a Polymer Free Sirolimus-eluting Coronary Stent System (VIVO ISARTM) Compared With Everolimus-eluting Durable Polymer Stent (XIENCE SkypointTM) in Patients Undergoing Percutaneous Coronary Intervention.

Coronary Artery Disease

Spain
Sohag University

Recruiting

Relationship Between Dyslipidemia and The Response of Diabetic Macular Edema to Intravitreal Injection of Anti Vascular Endothelial Growth Factor Agents

Diabetic Macular Edema

Egypt
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Recurrent Glioblastoma | Recurrent WHO Grade 4 Glioma

United States
Bayer

Recruiting

A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis (SIRIUS)

Thrombolysis | Symptomatic Proximal Deep Vein Thrombosis

Belgium, France, Italy, Netherlands, Canada, Germany, Czechia
University of Colorado, Boulder
American Heart Association

Recruiting

Fisetin to Improve Vascular Function in Older Adults

Aging | Endothelial Dysfunction | Arterial Stiffness

United States
Canadian Medical and Surgical Knowledge Translation...
Unity Health Toronto; University of Western Ontario, Canada

Not yet recruiting

Functional Investigation of Endothelial Function and Regenerative Cell Exhaustion (FIERCE)

Diabetes Mellitus, Type 2

Canada
University of Sao Paulo
Hospital das Clínicas de Ribeirão Preto

Recruiting

Beetroot Juice Supplementation in Chronic Hypertensive Pregnancies (BEET_CH)

Hypertension | Pregnancy | Hypertension in Pregnancy

Brazil
Second Affiliated Hospital of Soochow University

Recruiting

A Clinical Study of Recombinant Human Vascular Endothelial Inhibitor in Combination With PRaG for Advanced Refractory Non-small Cell Lung Cancer

Advanced Solid Tumor | Refractory Tumor

China
The First Hospital of Jilin University

Recruiting

Early Tirofiban Administration After Intravenous Thrombolysis in Acute Ischemic Stroke

Acute Ischemic Stroke

China
Penn State University
American Heart Association

Not yet recruiting

Passive Calf Stretching Therapy in Peripheral Artery Disease

Peripheral Artery Disease | Claudication, Intermittent

United States
Imperial College London

Not yet recruiting

Endothelial Cell Activation and Total Pulmonary Resistance in PAH

Pulmonary Artery Hypertension
Texas Tech University

Recruiting

2 Weeks of Citrulline Supplementation on Arterial Function in Postmenopausal Women With Elevated Blood Pressure or Hypertension

Hypertension | Menopause

United States
Texas Tech University

Recruiting

Effects of L-citrulline Supplementation on Vascular Function in Metabolic Syndrome

Metabolic Syndrome | Menopause

United States
Zhongda Hospital

Not yet recruiting

DDX17 Orchestrate Septic Vascular Endothelial Pyroptosis by Controlling Gasdermin D Pore Formation

Sepsis | Septic Shock
Ibrahim Halil Sahin
Bayer

Not yet recruiting

Regorafenib in Combination With Pembrolizumab or Pembrolizumab for MSI-H Colorectal Cancer

MSI-H Colorectal Cancer

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna
University of Bologna

Not yet recruiting

Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy (EDIPE)

Preeclampsia | Hypertensive Disorder of Pregnancy

Italy
Allife Medical Science and Technology Co., Ltd.

Not yet recruiting

Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke

China
AbbVie

Recruiting

Observational Study of Adult Participants With Diabetic Macular Edema and Suboptimal Response to Anti-Vascular Endothelial Growth Factor Treated With Dexamethasone Intravitreal Implant

Diabetic Macular Edema

Greece, Portugal, Belgium, United Kingdom, Italy, Israel, China, Germany
Rio de Janeiro State University
Universidade Federal Fluminense; Rio de Janeiro State Research Supporting Foundation...

Recruiting

Obesity and Bariatric Surgery According to a Biopsychosocial Perspective.

Depression | Quality of Life | Obesity | Anxiety Disorders | Heart Rate Variability

Brazil
Anna Stanhewicz, PhD

Recruiting

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

Oxidative Stress | Gestational Diabetes | Vascular Endothelial Function

United States
Anna Stanhewicz, PhD

Recruiting

Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

Gestational Diabetes | Vascular Endothelial Function

United States
Attikon Hospital

Recruiting

The Effect of Coenzyme Q10 on Endothelial, Vascular and Myocardial Function

Non-Alcoholic Fatty Liver Disease

Greece
University of Oklahoma
Amazentis SA

Recruiting

Urolithin A Supplementation in Middle-aged Adults With Obesity

Obesity | Cognitive Impairment | Vascular Dementia

United States
University of Catania

Recruiting

Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis

Atherosclerosis | Endothelial Dysfunction | Peri-Implantitis | Peri-implant Mucositis

Italy
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery (SOLSTICE)

Vascular Diseases | Endothelial Dysfunction | Kidney Injury | Brain Disease | Vascular Inflammation

United States
InCor Heart Institute

Recruiting

The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers (RE-AGES)

Coronary Artery Disease | Menopause | Endothelial Dysfunction

Brazil
Mineralys Therapeutics Inc.

Recruiting

A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen

Hypertension

United States
University of California, Davis
National Cancer Institute (NCI); Amino Up Chemicals Co., Ltd.

Recruiting

Standardized Extract of Cultured Lentinula Edodes Mycelia (AHCC®) in Ovarian Cancer Patients on Adjuvant Chemotherapy

Fallopian Tube Carcinoma | Peritoneal Carcinoma | Ovarian Epithelial Carcinoma

United States
Rio de Janeiro State University

Recruiting

Glycemic Patterns After Bariatric Surgery and High Glycemic Variability and Hypoglycemia Unawareness Risk Factors

Bariatric Surgery

Brazil
Algemeen Ziekenhuis Maria Middelares

Recruiting

Extensive CArdioVAscular Characterization and Follow-up of Patients Receiving Immune Checkpoint Inhibitors (CAVACI)

Cancer | Atherosclerosis | Cardiotoxicity | Diastolic Dysfunction | Immune Checkpoint Inhibitor-Related Myocarditis | Immune-related Adverse Event | Cardiac Abnormalities, Variable

Belgium

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