Search clinical trials for: Endotoxin challenge

Total 1539 results

National Jewish Health

Not yet recruiting

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma (Nasal-LPS)

Asthma | Asthma; Eosinophilic

United States
University of California, Los Angeles

Completed

An Inflammatory Challenge Using Endotoxin

Inflammatory Response | Alcohol Use Disorder | Craving | Depressed Mood

United States
Laureate Institute for Brain Research, Inc.

Completed

Lipopolysaccharide (LPS) Challenge in Depression

Major Depressive Disorder

United States
Janssen Research & Development, LLC

Completed

A Study of Adalimumab on Inflammatory Mediators Following a Systemic Endotoxin Challenge

Healthy

Belgium
University of Alabama at Birmingham
American Fibromyalgia Syndrome Association

Completed

The Innate Central Nervous System Immune Response to an Experimental Immune Challenge in People With Fibromyalgia

Fibromyalgia

United States
Hospices Civils de Lyon

Completed

Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk Prevention (SINFONI)

Cardiometabolic Risk | Abdominal Obesity

France
Janssen Research & Development, LLC

Completed

A Study Exploring the Use of Vaccine and Antigen Challenges for Immune Monitoring in Healthy Participants

Healthy

Belgium
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Development of Novel Non-invasive Inflammometry Following Lipopolysaccharide, Endotoxin (LPS) Challenge in Healthy Volunteers

Healthy

Germany
GlaxoSmithKline

Completed

Endotoxin Challenge Study For Healthy Men and Women

Pulmonary Disease, Chronic Obstructive

Germany
Pfizer

Terminated

A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model (POM)

Healthy

United States
AstraZeneca

Completed

Study to Investigate the Effect of a Single Dose of AZD7624 on Inflammation Caused by an Endotoxin Challenge

LPS Challenge, Neutrophils

United Kingdom
OPKO Health, Inc.

Completed

Effects of TT301 on Cytokine Levels Post Endotoxin Challenge

Traumatic Brain Injury

United States
University of Lausanne
Centre Hospitalier Universitaire Vaudois

Completed

Lactate Metabolism After an Endotoxin Challenge in Healthy Humans

Sepsis

Switzerland
University of California, Los Angeles

Completed

Cytokine-Associated Depression and Social Pain

Depression

United States
Dr. George Luciuk

Recruiting

Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing Immunotherapy or Oral Challenges

Hypersensitivity | Anaphylaxis

Canada
Institutul de Urgenţă pentru Boli Cardiovasculare...

Recruiting

Portal Vein Pulsatility Index to Assess Fluid Intolerance

Venous Congestion

Romania
McMaster University

Not yet recruiting

Measurements of Inflammation Induced by Allergen Inhalation Challenge in Mild Allergic Asthma (MATT)

Mild Asthma

Canada
University of Texas, El Paso
National Institute on Minority Health and Health Disparities (NIMHD)

Recruiting

Evidence-based Intervention to Improve Walking Engagement in El Paso, Texas

Physical Activity | Activity Trackers

United States
Centre for Human Drug Research, Netherlands

Recruiting

Deep Phenotyping of Cutaneous Lupus Erythematosus

Cutaneous Lupus Erythematosus

Netherlands
University of Leicester
University Hospitals, Leicester

Not yet recruiting

Ischaemic Lesions in Acute Intracerebral Haemorrhage (CHALLENGE-ICH)

Intracerebral Haemorrhage
University of Cologne

Recruiting

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges (RESERVE)

Hyponatremia

Germany
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (DACAT)

Drug Hypersensitivity | Drug-Induced Anaphylaxis | Antibiotic Allergy | Drug Allergy | Beta Lactam Adverse Reaction | Cephalosporin Allergy | Cephalosporin Reaction

United States
Lakehead University
Illinois Institute of Technology, Chicago, USA

Recruiting

Honest, Open, Proud - College for Post-Secondary Students With Mental Health Challenges

Mental Health Issue | Stigmatization | Disclosure

Canada
Chinese PLA General Hospital

Not yet recruiting

Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.

PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma
Humanitas Clinical and Research Center
European Society of Intensive Care Medicine

Not yet recruiting

Fluid Challenge in Intensive Care The FENICE II Study (FENICE II)

Critical Illness | Septic Shock

Italy
CentraCare

Recruiting

Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness (PHOENIX)

Fluid Responsiveness

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Peripheral Tissue Perfusion in Intensive Care (INPPEREA)

Acute Circulatory Failure
University Hospital, Caen

Recruiting

Haemodynamic and Respiratory Effects of a Low Positive End Expiratory Pressure Associated With a Fluid Challenge in Knee-chest Position (OPTIPEP)

Surgery

France
VistaGen Therapeutics, Inc.

Recruiting

Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-3) (PALISADE-3)

Social Anxiety Disorder

United States
University of Parma
Foundation for Liver Research; Azienda Ospedaliero-Universitaria di Parma; National... and other collaborators

Recruiting

Precision Nutrition to Improve Cardiometabolic Health With Dietary (Poly)Phenols (PRE-CARE-DIET)

Obesity | Cardiometabolic Health | Individual Variability in (Poly)Phenol Metabolism | Personalized Dietary Intervention

Italy
Craig Erickson
Healx Limited

Recruiting

Placebo-Controlled, Single-Dose Challenge Study of Gaboxadol in Adult Males With Fragile X Syndrome (FXS)

Fragile X Syndrome

United States
Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Development of a Novel Non-invasive Inflammometry Following Allergen Challenge in Patients With Mild Allergic Asthma

Mild Allergic Asthma

Germany
James Tarbox, MD
Texas Tech University Health Sciences Center

Recruiting

Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge

Penicillin Allergy

United States
University of Michigan

Recruiting

Michigan Food and Atopic Dermatitis (M-FAD) Program - Molecular Analytics Project

Healthy | Atopic Dermatitis | Food Allergy

United States
Scandinavian Biopharma AB
Johns Hopkins Bloomberg School of Public Health

Recruiting

Pre-Study of Wild Type Enterotoxigenic E. Coli (ETEC) Strain for Verification of a Planned Challenge Dose

ETEC Diarrhea

United States
Kilis 7 Aralik University
Hasan Kalyoncu University

Not yet recruiting

Impact of Workload and Fatigue on Sleep in OR Nurses

Shift Work | Sleep Perception

Turkey
Poznan University of Physical Education

Not yet recruiting

Effects of Krill Oil on Intestinal Integrity Markers in Elite Rowers.

Endothelial Dysfunction
Imperial College London

Recruiting

PsilOCD: A Pharmacological-Challenge Feasibility Study

Obsessive-Compulsive Disorder

United Kingdom
Hvivo
Pfizer

Recruiting

Dose, Safety, and Pathogenicity of a New Influenza B Strain

Influenza B

United Kingdom
Bhumibol Adulyadej Hospital

Not yet recruiting

Fluid Responsiveness in Prone Patients

Fluid Responsiveness
Chen Xiaoping

Recruiting

Comparing the Prognosis of Patients With HCC and PVTT Treated With Surgery Versus Locoregional Therapy.

Hepatocellular Carcinoma

China
Stanford University
Challenger Health, LLC

Not yet recruiting

The Effect of a Bioactive Fabric Sleeve

Recovery

United States
South Valley University

Recruiting

Acetylcholine Iontophoresis As A New Challenge With Type 2 Diabetic Peripheral Neuropathy: A Possible New Therapy

Type 2 Diabetes Mellitus | Peripheral Neuropathy

Egypt
Leiden University Medical Center

Recruiting

Non-Invasive Portal and Hepatic Vein Pressure Estimation (NONEEDLES)

Portal Hypertension

Netherlands
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
University of Miami

Recruiting

Yoga Training and Retinal Vasculature With Parkinson's Disease

Cognitive Change

United States
Northern Ontario School of Medicine

Recruiting

Evaluation of a Direct Oral Penicillin Challenge in a Rural Community (DOC)

Allergy Penicillin

Canada
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Recruiting

Hydrodissection in Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

Taiwan
Federal Research and Clinical Centre of Intensive...

Recruiting

Comparing Fluid Responsiveness Assessment Methods in Patients With Impaired Consciousness

Cognitive Impairment | Hypotension

Russian Federation
Ifakara Health Institute
University of Oxford

Not yet recruiting

In-vivo Transmission Model in Semi-immune Adults

Controlled Human Malaria Infection | Malaria Transmission | Induced Blood Stage Malaria Infection | Malaria Challenge

Tanzania

Search clinical trials for: Endotoxin challenge

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