Search clinical trials for: Evaluate the anti-tumor Efficacy, Safety, Tolerability,Pharmacokinetics and Immunogenicity

Total 483177 results

National Institute of Allergy and Infectious Diseases...

Recruiting

Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.

HIV

United States
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Immunogenicity, and Pharmacokinetics of GR2102 in Healthy Adult

Respiratory Syncytial Virus Infections

China
Novavax

Not yet recruiting

A Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine and Influenza Combination Vaccine

COVID-19
Imunon

Recruiting

Study to Evaluate the Safety & Immunogenicity of IMNN-101 Administered in Healthy Adults Previously Vaccinated Against SARS-CoV-2

SARS CoV 2 Infection

United States
International AIDS Vaccine Initiative
Universidad de Zaragoza; Biofabri, SLU

Not yet recruiting

A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in IGRA Positive Adolescents and Adults Living in a TB Endemic Region.

Tuberculosis (TB)
National Institute of Allergy and Infectious Diseases...
Duke University; National Institutes of Health (NIH); Department of Health and... and other collaborators

Not yet recruiting

A Clinical Trial in Adult Participants Without HIV and in Overall Good Health to Evaluate the Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 Followed by CH505 TF chTrimer Boost Both Adjuvanted With Either Lipid Nanoparticles (LNPs) or 3M-052-AF + Alum

HIV

United States, South Africa
Biogen

Recruiting

A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male Participants

Healthy Volunteer

United States
JHM BioPharma (Tonghua) Co. , Ltd.

Recruiting

A Phase I/II, Randomized, Double-blind, Placebo, and Active Controlled Clinical Study to Evaluate the Safety, Tolerability, Immunogenicity, and Preliminary Efficacy of JHM03 in Subjects With Moderate to Severe Glabellar Lines

Moderate to Severe Glabellar Lines

China
WestVac Biopharma Co., Ltd.
WestVac Biopharma (Guangzhou) Co., Ltd.

Recruiting

A Phase 3 Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of Booster Vaccination With Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell)

COVID-19

China
Yisheng Biopharma (Singapore) Pte. Ltd.

Not yet recruiting

A Phase I, The Study to Evaluate the Safety, Immunogenicity and Efficacy of YS-HBV-002

Chronic Hepatitis b
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

A Clinical Trial Evaluated the Safety and Tolerability, Pharmacokinetic and Pharmacodynamics Profile, and Immunogenicity of a Single Dose of JS010 Injection in Healthy Subjects

Migraine

China
CanSino Biologics Inc.

Recruiting

A Clinical Trial to Evaluate the Immunogenicity and Safety of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) in Adults Aged 18 to 55 Years

Meningococcal Meningitis

Indonesia
Osivax
Centre for the Evaluation of Vaccination Hôpital Cochin Assistance Publique...

Recruiting

First-in-human Study to Evaluate the Safety and Immunogenicity of Three Dose Levels of the OVX033 Coronavirus Vaccine Candidate in Healthy Volunteers

Coronavirus

France
CanSino Biologics Inc.

Recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over

Tetanus

China
CNBG-Virogin Biotech (Shanghai) Ltd.

Recruiting

A PhaseⅡ Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine

SARS-CoV-2 Infection

China
CNBG-Virogin Biotech (Shanghai) Ltd.
Shulan (Hangzhou) Hospital

Recruiting

A Phase 1 Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine

SARS-CoV-2 Infection

China
Aimei Vacin BioPharm (Zhejiang) Co., Ltd.

Recruiting

A Clinical Trial to Evaluate the Immunogenicity and Safety of the 23-valent Pneumococcal Polysaccharide Vaccine in Healthy People

Pneumococcal Disease

China
CanSino Biologics Inc.

Recruiting

A Study to Evaluate the Safety and Immunogenicity of ChAdOx1-VZV in Healthy Adults Aged 50-65 Years

Herpes Zoster

Canada
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Mosaic Hexavalent Influenza Vaccine VRC-FLUMOS0116-00-VP (FluMos-v2) in Healthy Adults

Influenza

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Immunogenicity of Two Doses of DCVC H1 HA mRNA-LNP in Healthy Adults

Influenza

United States
AIM Vaccine Co., Ltd.
Zhejiang Provincial Center for Disease Control and Prevention

Not yet recruiting

A Phase II Clinical Trial to Evaluate the Immunogenicity and Safety of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021)

SARS-CoV-2

China
Shanxi Kangbao Biological Product Co., Ltd.
Institute of Pathogen Biology, Chinese Academy of Medical Sciences

Recruiting

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects

Hiv

China
Sinocelltech Ltd.

Not yet recruiting

A Study to Evaluate the Immunogenicity and Safety of A Recombinant Protein COVID-19 Vaccine as Booster Vaccines

COVID-19 | SARS-CoV-2 Infection
Mabwell (Shanghai) Bioscience Co., Ltd.

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetic Properties and Immunogenicity of 9MW3811 in Healthy Subjects

Idiopathic Pulmonary Fibrosis

China
Stemirna Therapeutics

Not yet recruiting

A Phase II/III Study to Evaluate the Immunogenicity and Safety and Efficacy of SWIM816 Vaccines for SARS-CoV-2

Safety | Immunogenicity
International AIDS Vaccine Initiative
National Institute of Allergy and Infectious Diseases (NIAID); Access to Advanced...

Not yet recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of a Prophylactic HIV Vaccine Candidate

Hiv
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study Evaluates the Safety, Pharmacokinetics, Immunogenicity and Efficacy of QLS31903 in Advanced Solid Tumor Patients

Advanced Solid Tumors

China
Fundacion Clinic per a la Recerca Biomédica
Polymun Scientific GmbH

Recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein SOSIP v8.2 763 Vaccine, Adjuvanted With MPLA Liposomes, in Healthy, HIV-Uninfected Adults (HIVAC-FOUND)

Healthy

Spain
International Vaccine Institute

Recruiting

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of the Sm-p80 + GLA-SE (SchistoShield®) Candidate Vaccine in Healthy Adults in Burkina Faso and Madagascar

Schistosomiasis

Burkina Faso, Madagascar
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults

Influenza

United States
L & L biopharma Co., Ltd., Shanghai China

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LB4330 in Patients With Advanced Solid Tumors（MEETCD8-001） (MEETCD8-001)

Solid Tumor

China
ModernaTX, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.

Cytomegalovirus Infection

United States
Laboratorio Elea Phoenix S.A.
Syneos Health

Recruiting

Double-blind Study to Evaluate the PK, Efficacy, Safety and Immunogenicity of MB12 Versus Keytruda® in Stage IV NSCLC

Non Small Cell Lung Cancer Metastatic

Argentina
Clarametyx Biosciences, Inc.

Recruiting

A 2-Part First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of CMTX-101

Community-acquired Pneumonia | Bacterial Pneumonia

United States
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Recruiting

A Trial Evaluate the Immunogenicity and Safety of Recombinant COVID-19 Omicron-Delta Variant Vaccine (CHO Cell)

COVID-19

Uzbekistan
Boryung Biopharma Co., Ltd.

Not yet recruiting

To Evaluate the Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in Healthy Children Aged From 24mons-15yrs

Hepatitis A | Hep A

Korea, Republic of, Thailand
International Vaccine Institute
Massachusetts General Hospital; EuBiologics Co.,Ltd

Recruiting

Dose Escalation Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Healthy Adults

Cholera Vaccination Reaction

Korea, Republic of
Sinocelltech Ltd.

Not yet recruiting

A Study to Evaluate the Immunogenicity and Safety of a Recombinant Protein COVID-19 Vaccine SCTV01E-1 in Population Aged Above 18 Years

COVID-19 | SARS-CoV-2 Infection
The Aurum Institute NPC
Coalition for Epidemic Preparedness Innovations

Recruiting

Phase 2a Trial to Evaluate Safety and Immunogenicity of COVID-19 Vaccine Strategies in HIV-infected/Uninfected Adults. (AUR1-8-341)

COVID-19

South Africa
Huashan Hospital

Recruiting

A Real-world Study to Evaluate the Safety and Immunogenicity of a Third-dose Booster After Two Doses of an Inactivated COVID-19 Vaccine

COVID-19 | Vaccine Reaction

China
Vaxxinity, Inc.

Recruiting

A Phase 1 Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-313 in Healthy Participants

Migraine

Belgium
D'Or Institute for Research and Education
Bill and Melinda Gates Foundation; University of Oxford

Not yet recruiting

An Observer-blind, Cohort Randomized, Exploratory Phase 3 Study to Evaluate the Safety and Immunogenicity of Recombinant Covid-19 Vaccine, mRNA Covid-19 Vaccine and Recombinant SARS-CoV-2 Trimeric S-protein Subunit Vaccine as 4th Dose in Individuals Primed/ Boosted With Various Regimens

COVID-19

Brazil
LG Chem

Not yet recruiting

Study to Evaluate the Immunogenicity and Safety of LBVD(Hexavalent Vaccine), Given to Healthy Infants at Primary Series

Hepatitis B | Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Influenzae Type B Infection
ModernaTX, Inc.

Recruiting

A Study to Evaluate the Safety and Immunogenicity of the mRNA COVID-19 Vaccines in Healthy Children Between 6 Months to Less Than 6 Years of Age

SARS-CoV-2

United States, Puerto Rico
Green Cross Corporation

Recruiting

Evaluate the Safety and Immunogenicity After MG1111(BARICELA Inj.) as 2nd Vaccination in 4 ~ 6 Year Old Healthy Children With a History of 1st Varicella Vaccination

Varicella

Korea, Republic of
GlaxoSmithKline
Affinivax, Inc.

Recruiting

A Phase 2 Study to Evaluate the Safety, Tolerability, and Immunogenicity of AFX3772 Vaccine in Healthy Infants

Pneumococcal Infections | Pneumonia, Pneumococcal | Pneumonia, Bacterial

United States, Puerto Rico
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Recruiting

A Study of TQH2722 Injection to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Immunogenicity in Healthy Adult Subjects

Atopic Dermatitis

China
Walvax Biotechnology Co., Ltd.
Shanghai RNACure Biopharma Co., Ltd.

Not yet recruiting

A Phase 1b Trial to Evaluate the Safety and Immunogenicity of a SARS-CoV-2 mRNA Chimera Vaccine Against COVID-19

COVID-19
Walvax Biotechnology Co., Ltd.
Shanghai RNACure Biopharma Co., Ltd.

Not yet recruiting

A Phase 1a Trial to Evaluate the Safety and Immunogenicity of a SARS-CoV-2 mRNA Chimera Vaccine Against COVID-19

COVID-19
Yabao Pharmaceutical Group

Not yet recruiting

A Phase Ia Clinical Study to Evaluate the Safety, Tolerability, PK and Immunogenicity of YBSW015 in Healthy Subjects

Coronavirus Disease 2019

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