Search clinical trials for: Fibroblast inhibitors

Total 64477 results

Chang Gung Memorial Hospital

Recruiting

Evaluation of 68Ga-FAPI-46 and 18F-FDG PET/CT Imaging for Detecting Recurrent Tumor Lesions in Patients of Ovarian Cancer

Ovarian Cancer

Taiwan
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

68 Gallium-Fibroblast Activating Protein Inhibitors-46 Positron Emission Tomography - Computerized Tomography for Molecular Assessment of Fibroblast Activation and Risk Assessment in Solid Tumors (FAPI)

Solid Tumor, Unspecified, Adult

Italy
Jules Bordet Institute

Recruiting

Molecular Imaging of FAP Expressing Cancer-associated Fibroblasts in NSCLC Treated With Immune-checkpoint Inhibitors (LIFE)

Non Small Cell Lung Cancer

Belgium
The First Affiliated Hospital of Xiamen University

Recruiting

Characterizing Spondyloarthritis With 68Ga-FAPI PET/CT

Ankylosing Spondylitis | Spondyloarthritis | Axial Spondyloarthritis

China
Peking Union Medical College Hospital

Not yet recruiting

Characterizing Histiocytosis With 68Ga-FAPI PET/CT

Histiocytosis

China
Peking Union Medical College Hospital

Recruiting

FAPI-PET/CT in Psoriatic Arthritis

Psoriatic Arthritis

China
Peking Union Medical College Hospital

Not yet recruiting

Head-to-head Comparison of Diagnosis Value of Pulmonary Fibrosis on 68Ga-FAPI-04 and 18F-FDG PET-CT

Pulmonary Fibrosis

China
Peking Union Medical College Hospital

Recruiting

68Ga-FAPI PET/MR for Atherosclerosis

Atherosclerosis

China
Peking Union Medical College Hospital

Recruiting

Characterizing Rheumatoid Arthritis With 68Ga-FAPI PET/CT

Arthritis

China
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
Peking Union Medical College Hospital

Recruiting

Characterizing IgG4-RD With 68Ga-FAPI PET/CT

IgG4-related Disease

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Incyte Corporation

Recruiting

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

Bladder Cancer | NMIBC | Urothelial Carcinoma Recurrent | Non-Muscle Invasive Bladder Cancer

United States
University of Colorado, Denver
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

COMT Inhibition Among Individuals With Comorbid AUD/ADHD

Attention Deficit Hyperactivity Disorder | Alcohol Use Disorder

United States
National Institute of Diabetes and Digestive and...

Completed

Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers

Healthy Volunteers

United States
Janssen Research & Development, LLC

Active, not recruiting

A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations (THOR)

Urothelial Cancer

Korea, Republic of, United States, Italy, Spain, Japan, United Kingdom, Belgium, Israel, China, Austria, France, Canada, Taiwan, Turkey, Germany, Russian Federation, Bulgaria, Poland, Greece, Brazil, Netherlands, Australia, Argentina, Mexic... and more
University of California, Berkeley
University of California, San Francisco; Lawrence Berkeley National Laboratory

Completed

Dopaminergic Mechanisms Underlying Human Social Behavior

Executive Function | Decision Making | Dopamine

United States
Basilea Pharmaceutica

Terminated

Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma (FIDES-03)

Gastric Adenocarcinoma

Spain, United States, Korea, Republic of, Belgium, Russian Federation, United Kingdom, Italy, France, Turkey, Germany, Poland, Brazil, Australia, Argentina, Chile
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Mesenchymal Chondrosarcoma | Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Malignant Peripheral Nerve Sheath Tumor | PEComa | Synovial Sarcoma | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Undifferentiated High Grade Pleomorphic... and other conditions

United States, Canada, Puerto Rico
Northwestern University
National Cancer Institute (NCI); Boehringer Ingelheim; Robert H. Lurie Cancer...

Active, not recruiting

Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A | Fibroblast Growth Factor Basic Form Measurement | FLT3 Internal Tandem Duplication

United States
Eisai Co., Ltd.

Active, not recruiting

A Study of E7090 as Monotherapy and in Combination With Other Anticancer Agents in Participants With Estrogen Receptor Positive (ER+) and Human Epidermal Growth Receptor 2 Negative (HER2-) Recurrent/Metastatic Breast Cancer

Breast Neoplasms

Japan
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

Glioblastoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Advanced Solid Tumors | Triple Negative Breast Cancer | Biliary Tract Cancers

United States, Argentina, Australia, Canada, Chile, Colombia, France, Germany, Israel, Italy, Korea, Republic of, Russian Federation, Spain, Switzerland, Taiwan, Thailand, United Kingdom
Roswell Park Cancer Institute
AIM ImmunoTech Inc.

Terminated

Chemokine-Modulatory Regimen for Recurrent Resectable Colorectal Cancer

Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States
Basilea Pharmaceutica

Completed

Derazantinib and Atezolizumab in Patients With Urothelial Cancer (FIDES-02)

Urothelial Carcinoma

United Kingdom, Korea, Republic of, Italy, Canada, France, Spain, Germany, United States, Hungary, Australia, Poland, Switzerland, Czechia, Austria
Peking Union Medical College Hospital

Completed

Analyse of Diagnosis Value of Keloid on 68Ga- FAPI-04 PET-CT

Keloid

China
Incyte Corporation

Terminated

Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)

Metastatic Urothelial Carcinoma | Unresectable Urothelial Carcinoma

Spain, France, United States, Italy, Japan, Ireland, Slovakia, Austria, Belgium, Canada, Finland, Germany, Poland, Portugal, Romania, United Kingdom
Peking Union Medical College Hospital

Unknown

Characterizing Inflammatory Bowel Disease With 68Ga-FAPI PET/CT

Inflammatory Bowel Disease

China
Scynexis, Inc.

Completed

Oral Ibrexafungerp (SCY-078) vs Standard-of-Care Following IV Echinocandin in the Treatment of Invasive Candidiasis

Mycoses | Candidemia | Candidiasis, Invasive

United States, El Salvador, Germany, Guatemala, Honduras
Peking Union Medical College Hospital

Unknown

Characterizing SAPHO With 68Ga-FAPI PET/CT

SAPHO Syndrome

China
M.D. Anderson Cancer Center
Bristol-Myers Squibb

Terminated

Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGF

Colorectal Cancer | Colorectal Adenocarcinoma

United States
GlaxoSmithKline

Completed

Study to Evaluate GSK3052230 in Combination With Paclitaxel and Carboplatin, or Docetaxel or as Single Agent in Subjects With Solid Malignancies and Deregulated Fibroblast Growth Factor (FGF) Pathway Signaling

Neoplasms

United States, Denmark, Spain, Belgium, United Kingdom, Russian Federation, Netherlands
Second Affiliated Hospital of Nanchang University

Unknown

Recombinant Bovine Basic Fibroblast Growth Factor for the Treatment of Radiation Induced Oral Mucositis

Stomatitis
Teresa Helsten, MD
Eisai Co., Ltd.

Withdrawn

Study of Lenvatinib in Patients With Advanced Cancer and Aberrations in FGF/FGFR Signaling

Cancer

United States
Bristol-Myers Squibb
AbbVie

Completed

Study of Elotuzumab in Combination With Lenalidomide and Dexamethasone in Subjects With Multiple Myeloma and Various Levels of Renal Function

Multiple Myeloma

United States
University Hospital, Montpellier

Completed

Pharmacokinetic of Doripenem and Piperacillin/Tazobactam in More Than 120 kg Critically Ill Patients

Septic Shock

France
Far Eastern Memorial Hospital

Unknown

Function and Modulation of Fibulin-1 Assembly in Nucleus of Corneal Fibroblasts

Function of Mitomycin C in Cornea
European Organisation for Research and Treatment...

Completed

Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Dermatofibrosarcoma Protuberans or Giant Cell Fibroblastoma

Sarcoma

France, Belgium, Netherlands, United Kingdom
Xijing Hospital
Yantai Medgenn Ltd.

Unknown

Impact of Endostar Combined With Chemotherapy on the Angiogenesis of Advanced Non-small Cell Lung Cancer (NSCLC)

Lung Neoplasms

China
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemia

Candidemia | Invasive Candidiasis

Taiwan
University of California, Irvine
Eurofins Viracor

Not yet recruiting

Prospect Eval of Efficacy of CMV-TCIP Direct Letermovir Prophylax After Allogen Hemato Cell Transpla

CMV | Allogeneic Stem Cell Transplantation

United States
Guangdong Provincial People's Hospital

Not yet recruiting

Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML

Acute Myeloid Leukemia

China
Iffat Anwar Medical Complex

Recruiting

Assessment of Different Clinical Techniques to Treat Patients With Chronic Low Back Pain (CLBP)

Chronic Low Back Pain (CLBP)

Pakistan
University of Pennsylvania

Not yet recruiting

Letrozole and Misoprostol for Early Pregnancy Loss Management: A Prospective Pilot Cohort Study (LeMi)

Miscarriage | Early Pregnancy Loss | Miscarriage in First Trimester

United States
Shanghai Zhongshan Hospital

Not yet recruiting

IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly Patients With Acute Coronary Syndrome (OPTION2)

Coronary Artery Disease
Bayer

Not yet recruiting

A Study to Learn More About How Well BAY 2927088 Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Human Epidermal Growth Factor Receptor 2 (HER2)

Advanced Non-small Cell Lung Cancer | HER2 Mutation

United States, Korea, Republic of, Belgium, China, Japan, Taiwan, Denmark, Germany, Israel, Italy, United Kingdom, Bulgaria, Portugal, Switzerland, Greece, Turkey, Sweden, France, Singapore, Mexico, Spain, Netherlands, Poland, Brazil, A... and more
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Gumarontinib Combined With 3rd EGFR-TKI in Patients With Non-small Cell Lung Cancer.

Non-small Cell Lung Cancer
Medical University of Lodz
Poznan University of Medical Sciences; Medical Research Agency, Poland; Clinical... and other collaborators

Not yet recruiting

Comparison of Ustekinumab, Infliximab and Combination Therapy in Moderately to Severely Active Ulcerative Colitis (COMBO-UC)

Inflammatory Bowel Diseases | Ulcerative Colitis
Universität des Saarlandes

Recruiting

Pharmacokinetics of Bisoprolol and SGLT2i in Acutely Decompensated Heart Failure (BISO-ADHF)

Acute Decompensated Heart Failure

Germany
Rigshospitalet, Denmark
Aarhus University Hospital Skejby

Recruiting

The Nordic Aortic Valve Intervention Trial 4 (NOTION-4) (NOTION-4)

Heart Diseases | Cardiovascular Diseases | Aortic Valve Stenosis | Heart Valve Diseases | Valve Disease, Aortic

Denmark
New Approaches to Neuroblastoma Therapy Consortium
Nationwide Children's Hospital; United Therapeutics; Children's Neuroblastoma...

Not yet recruiting

NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

Neuroblastoma

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Modeling Amyotrophic Lateral Sclerosis With Fibroblasts (FIBRALS)

Amyotrophic Lateral Sclerosis

France

Search clinical trials for: Fibroblast inhibitors

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