Search clinical trials for: First generation vaccine

Total 28320 results

ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Biochemically Recurrent Prostate Carcinoma | Metastatic Prostate Carcinoma | Prostate Adenocarcinoma | Stage IVB Prostate Cancer AJCC v8

United States
Centre for Infectious Disease Research in Zambia
Institut National de la Santé Et de la Recherche Médicale, France; Imperial... and other collaborators

Active, not recruiting

Human Challenge With Live-attenuated Rotavirus to Assess Next-generation Rotavirus Vaccines in Africa

Diarrhea | Diarrhea Rotavirus

Zambia
Hannover Medical School

Terminated

Pharmacovigilance in Gerontopsychiatric Patients (GAP)

Depression | Schizophrenia | Anxiety Disorders | Dementia | Psychosomatic Disorders

Germany
Tehran University of Medical Sciences
Pasteur Institute of Iran, Tehran, Iran; Razi Vaccine and Serum Research Institute and other collaborators

Completed

Safety/Efficacy Trial of Killed Leishmania Vaccine in Volunteers With no Response to Leishmanin

Healthy

Iran, Islamic Republic of
Tehran University of Medical Sciences
Pasteur Institute of Iran, Tehran, Iran; Razi Vaccine and Serum Research Institute and other collaborators

Completed

Safety/Efficacy Trial of Killed Leishmania Vaccine in Volunteers With Positive Response to Leishmanin (LST>0)

Healthy

Iran, Islamic Republic of
McMaster University
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

A Trial of a Next Generation COVID-19 Vaccine Delivered by Inhaled Aerosol (AeroVax)

COVID-19 Infection

Canada
Changchun BCHT Biotechnology Co.
The First Affiliated Hospital of Yunnan University of Traditional Chinese... and other collaborators

Not yet recruiting

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of the Fully Human Anti-tetanus Toxin Monoclonal Antibody A82 / B86 Injection Combination Formulation

Clostridium Tetanus
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in mHSPC Patients

Metastatic Prostate Cancer | Therapy, Directly Observed

China
Germans Trias i Pujol Hospital

Not yet recruiting

Precision Psychiatry for Depression: Immune Response and Affective Symptoms as Predictors of Response to Antidepressants (LYMPHODEP)

Depression | Inflammation | Immunity | Antidepressants

Spain
First Affiliated Hospital of Zhejiang University

Recruiting

Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Venlafaxine Hydrochloride Sustained-release Tablets in Patients With Major Depression Disorder

Major Depression Disorder

China
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study Of SY-3505 Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC

Non-small Cell Lung Cancer

China
Yan'an Affiliated Hospital of Kunming Medical University
Shanghai Zhongshan Hospital; Kunming Chenggong District People's Hospital

Not yet recruiting

The 5th Generation Tele-Robotic-Assisted Percutaneous Coronary Intervention: A First-in-Human Trial

Myocardial Ischemia | Cardiovascular Diseases | Coronary Artery Disease | Coronary Disease | Arteriosclerosis
Clover Biopharmaceuticals AUS Pty Ltd

Recruiting

First-in-human Safety and Immunogenicity Study of SCB-1019 in Healthy Adults

Respiratory Syncytial Virus Infection

Australia
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Prostatic Neoplasms | Metastatic Castration-resistant Prostate Cancer (mCRPC)

Australia, Germany, United States, Puerto Rico, Israel, Korea, Republic of, Taiwan, China, Costa Rica, Guatemala, Spain, France, Hong Kong, Portugal, Romania, Chile, Czechia, Hungary, Italy, Sweden, Turkey, United Kingdom, Estonia, Ir... and more
Nektar Therapeutics

Recruiting

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis (REZOLVE-AD)

Moderate to Severe Atopic Dermatitis

Spain, Czechia, United States, Australia, Croatia, Bulgaria, Poland, Canada, Germany, Hungary
Fujian Cancer Hospital
First Affiliated Hospital of Fujian Medical University; Fujian Provincial Hospital and other collaborators

Not yet recruiting

MRI Radiomics Combined With Pathomics on the Prediction of Molecular Classification and Prognosis of Endometrial Cancer

Endometrial Neoplasms

China
Osivax
Centre for the Evaluation of Vaccination Hôpital Cochin Assistance Publique...

Recruiting

First-in-human Study to Evaluate the Safety and Immunogenicity of Three Dose Levels of the OVX033 Coronavirus Vaccine Candidate in Healthy Volunteers

Coronavirus

France
Arcturus Therapeutics, Inc.
Novotech (Australia) Pty Limited; Seqirus

Recruiting

Safety and Immunogenicity First-in-human Dose-ranging Study of Self-Amplifying RNA Seasonal Influenza Vaccine in Adults

Influenza, Human

Australia
Statens Serum Institut
Bill and Melinda Gates Foundation; Aurum Institute; Leiden University Medical... and other collaborators

Recruiting

First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b (nTB-01)

Healthy

South Africa
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms

China
Fudan University

Recruiting

SRS for NSCLC With Oligo-residual Intracranial Disease After First-line 3rd Generation EGFR-TKI

Non-small Cell Lung Cancer | Brain Metastases

China
Sanofi

Recruiting

A Study to Investigate Vaccine Responses in Subcutaneous Amlitelimab Treated Atopic Dermatitis Participants Aged 18 Years and Older Compared With Placebo (HYDRO)

Dermatitis Atopic

Canada, United States
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY BD)

Bipolar Depression

Austria, Germany, Italy, Spain, United Kingdom
University Hospital, Antwerp
Kom Op Tegen Kanker; Stichting tegen Kanker

Recruiting

First-in-human Interleukin-15-transpresenting Wilms' Tumor Protein 1-targeting Autologous Dendritic Cell Vaccination in Cancer Patients (IL15-TransDC)

Esophageal Cancer | Ovarian Cancer | Pancreas Cancer | Liver Cancer

Belgium
First Affiliated Hospital of Zhejiang University

Recruiting

Development and Application of Comprehensive Intervention Techniques for Adolescent Depression

Adolescent | Depressive Disorder

China
The First Affiliated Hospital with Nanjing Medical...
Novlead Inc.

Recruiting

A Clinical Study of Inhaled Nitric Oxide in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (NOVEL)

Chronic Obstructive Pulmonary Disease

China
Bill & Melinda Gates Medical Research Institute

Recruiting

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Malaria

United States
Immune Oncology Research Institute

Recruiting

Continuous Infusion of First-Generation 5-HT3 Receptor Antagonists in Combination With Dexamethasone

Pediatric Cancer

Armenia
Changchun BCHT Biotechnology Co.
The First Affiliated Hospital of Yunnan University of Traditional Chinese... and other collaborators

Not yet recruiting

Safety, Pharmacokinetics, and Pharmacodynamic Testing of Rabies mAb CBB 1

Rabies Virus Infection

China
First Affiliated Hospital of Chongqing Medical...
Southwest Hospital, China; Central South University; The Second Affiliated Hospital... and other collaborators

Recruiting

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) (STAR-AD)

Depression | Sequestra

China
H. Lee Moffitt Cancer Center and Research Institute
United States Department of Defense

Recruiting

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

Triple Negative Breast Cancer | HER2-positive Breast Cancer | Leptomeningeal Disease

United States
The Second Affiliated Hospital of Shandong First...

Recruiting

Clinical Study of Ametinib Combined With Bevacizumab in First-line Treatment of Advanced NSCLC With EGFR-mutations.

Non-small Cell Lung Cancer

China
The First Affiliated Hospital of Nanchang University
Shanghai Dengding BioAI Co.

Recruiting

Using Neoantigen Peptide Vaccine/Neoantigen-based DC to Treat Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumors

China
AIM Vaccine Co., Ltd.
First Affiliated Hospital Bengbu Medical College; Ningbo Rongan Biological...

Recruiting

Clinical Trial of COVID-19 Vaccine（SARS-CoV-2 Variant(Omicron BA.5) mRNA Vaccine） in Participants Aged 18 Years and Over

SARS-CoV-2

China
Brigham and Women's Hospital

Recruiting

First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers

Cholera | Cholera Vaccine Toxicity

United States
Emergex Vaccines Holding Ltd.

Not yet recruiting

Next Generation T-cell Vaccine Against Coronavirus Disease (COVID-19)

COVID-19 | Coronavirus | SARS-CoV-2 Infection

Philippines
GlaxoSmithKline
Biological E. Limited

Recruiting

Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adults

Typhoid Fever

Belgium
Dr. Inge Winter
Universität Münster

Not yet recruiting

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure (INTENSIFY)

Bipolar Depression | Major Depressive Disorder | Schizophrenia and Related Disorders

Israel
Second Xiangya Hospital of Central South University
The First Affiliated Hospital of Nanchang University; Xiangya Hospital of Central... and other collaborators

Recruiting

Exploring the Mechanism of Primary Resistance to Third-generation EGFR-TKIs as First-line Treatment in EGFR-positive Advanced NSCLC (PRECISE Study) (PRECISE)

Lung Cancer, Non-small Cell | Circulating Tumor DNA | EGFR Gene Mutation | EGFR-TKI Resistant Mutation | Primary Resistance

China
Stemirna Therapeutics

Recruiting

New Generation mRNA Booster Vaccine Against Emerging VOCs

Efficacy | Safety | Immunogenicity

Lao People's Democratic Republic
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma

United States
Regeneron Pharmaceuticals
BioNTech SE

Recruiting

A Trial to Learn How the Cancer Vaccine BNT116 in Combination With Cemiplimab Works and How Safe the Combination is in Adults With Advanced Non-small Cell Lung Cancer (EMPOWERVAX Lung 1)

Advanced Non-Small Cell Lung Cancer

United States, Korea, Republic of, Spain, Georgia, Taiwan, Germany, Turkey
AIM Vaccine Co., Ltd.
First Affiliated Hospital Bengbu Medical College; Ningbo Rongan Biological...

Not yet recruiting

A Cohort Study of SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine in Participants Aged 18 Years and Over in Chinese People

SARS-CoV-2
Shanghai Humantech Biotechnology Co. Ltd
Shanghai Changhai Hospital,The First Affiliated Hospital of Naval Medical...

Recruiting

Safety of Prodencel in the Treatment of Metastatic Castration-resistant Prostate Cancer (mCRPC)

Metastatic Castration-resistant Prostate Cancer

China
The Jackson Laboratory
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

A Deep Longitudinal Analysis of Next Generation Influenza Vaccines in Older Adults (FluVax3)

Aging | Influenza Vaccine | Vaccine Response | Dendritic Cell

United States
Pfizer

Recruiting

Real-World Study of Ceftazidime Avibactam in China (REACT)

Hospital Acquired Pneumonia | Complicated Intra Abdominal Infections | Ventilator Acquired Pneumonia

China
First Affiliated Hospital of Zhejiang University

Recruiting

Chinese Longitudinal and Systematic Study of Bioplar Disorder (CLASS-BD)

Major Depressive Disorder | Bipolar Disorder, Mixed | Affective; Disorder, Organic

China
Hannover Medical School
Else Kröner Fresenius Foundation

Recruiting

Priming of the NEonatal Immune System by Transfer of Maternal Immunity (NEST)

COVID-19 | Respiratory Infections in Children | Maternal Vaccine Exposure

Germany
Assistance Publique - Hôpitaux de Paris
Institut Pasteur; Pathogen Discovery Laboratory

Recruiting

Metatranscriptomic Next Generation Sequencing in First Trimester Trophoblast With Increased Fetal Nuchal Translucency (METAHCN) (METAHCN)

Increased Nuchal Translucency in the First Trimester of Pregnancy

France
Bioray Laboratories
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

Safety and Efficacy Evaluation of Next-generation CD19-UCART

Acute Lymphoblastic Leukemia | Non Hodgkin Lymphoma

Search clinical trials for: First generation vaccine

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