Search clinical trials for: HIF 1a

Total 927 results

Assiut University

Not yet recruiting

Hypoxia-induced Autophagy in the Pathogenesis of MAP

Hypoxia | Morbidly Adherent Placenta | Autophagy | Placenta
Ataturk Training and Research Hospital

Not yet recruiting

The Effect of Blood Carboxyhemoglobin Levels on Total Antioxidant (Tas), Total Oxidant(Tos), Hypoxia Inducible Factor-1a (hif1a) During Low-flow and Normal-flow Anesthesia

Carbon Monoxide Exposure
Bezmialem Vakif University

Suspended

Evaluation of the Effect of Sevoflurane and Propofol Hypotensive Anesthesia on Blood Antioxidant Levels and HIF 1 Levels

Hypoxia | Hypoxemia During Surgery

Turkey
José García de la Asunción

Completed

Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery

Ischemia-reperfusion Injury
Bezmialem Vakif University

Completed

Effect of Hypotensive Anesthesia on Cerebral Perfusion and Blood Antioxidant Levels and HIF 1a

Hypoxia, Brain | Hypoxemia During Surgery

Turkey
National Cancer Institute (NCI)

Completed

A Pilot Study of EZN-2968, an Antisense Oligonucleotide Inhibitor of HIF-1alpha, in Adults With Advanced Solid Tumors With Liver Metastases

Neoplasms | Liver Metastases

United States
Hoffmann-La Roche

Completed

A Study of Hypoxia-inducible Factor 1a (HIF1A) Messenger Ribonucleic Acid (mRNA) Antagonist (RO7070179), to Demonstrate Proof-of-mechanism in Adult Participants With Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular

United States
National Cancer Institute (NCI)

Completed

A Pilot Trial of Oral Topotecan for the Treatment of Refractory Advanced Solid Neoplasms Expressing HIF-1a

Neoplasms

United States
Genzyme, a Sanofi Company

Completed

Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication (WALK)

Atherosclerosis | Intermittent Claudication | Peripheral Vascular Disease

United States, United Kingdom, Germany
Merck KGaA, Darmstadt, Germany

Completed

Study To Evaluate The Immunogenicity And Safety Of r-hIFN Beta-1a (Rebif®) Using Clone 484-39 In Multiple Sclerosis

Relapsing Remitting Multiple Sclerosis
Seoul National University Hospital
GlaxoSmithKline; The Korean Urological Association

Completed

Effect of Dutasteride on HIF-1alpha and VEGF in the Prostate

Benign Prostatic Hyperplasia
University of Barcelona
University Ramon Llull; ICREA Academia; Institut de Neurociències de la Universitat... and other collaborators

Recruiting

Active Young, Healthy Mind. The YoungFitT Project (YoungFitT)

University Students

Spain
EDAP TMS S.A.

Recruiting

ES-HIFU, Prospective Data Collection of Patients Treated With Partial Gland HIFU Ablation for Prostate Cancer (ES-HIFU)

Prostate Cancer

Spain
RenJi Hospital

Not yet recruiting

Clinical Study of HIFU for Localized Prostate Cancer (HIFU)

Localized Prostate Cancer
Valneva Austria GmbH

Recruiting

Phase 1 Trial to Assess the Safety and Immunogenicity of an Inactivated, Adjuvanted Whole Zika Virus Vaccine Candidate (VLA1601) in Healthy Adults

Zika | Zika Virus Infection

United States
Actym Therapeutics, Inc.

Not yet recruiting

A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors

Solid Tumor

Australia
ENCell

Recruiting

Evaluate the Safety and Efficacy of EN001 in Patients With Charcot-Marie-Tooth Disease Type 1A

Charcot-Marie-Tooth Disease Type 1A

Korea, Republic of
Gerbera Therapeutics, Inc.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression (NuMom)

Postpartum Depression | Depression, Postpartum | Postnatal Depression | Post-partum Depression | Post-Natal Depression

United States
Vojtech Melenovsky, MD, PhD

Not yet recruiting

Metabolic Response to Iniciation of Heart Failure Therapy (GliF)

Heart Failure

Czechia
Chongqing Medical University

Recruiting

Prospective Multicenter Observational Study and Promotion of the Application of Focused Ultrasound in Allergic Rhinitis

Allergic Rhinitis

China
Nicholas DeVito, MD
Gateway for Cancer Research; Agenus Inc.

Not yet recruiting

Botensilimab and Balstilimab Optimization in Colorectal Cancer (BBOpCo)

Colorectal Cancer

United States
Radboud University Medical Center
Amsterdam UMC, location VUmc; ZonMw: The Netherlands Organisation for Health... and other collaborators

Recruiting

Effectiveness of Focal Therapy in Men With Prostate Cancer (ENFORCE)

Prostate Cancer | Prostate Neoplasm

Netherlands
Nutricia Research

Recruiting

Glin3: Assessment of the Glycemic Responses to Nutritional Products (GLIN#3)

Glycemic Response

Canada
Cairo University

Recruiting

Effect of HIFU on Sleep Quality Measures in Obese Doubled Chin Women

OBESITY

Egypt
Centre Leon Berard

Not yet recruiting

Evaluation of the High Intensity Focused Ultrasound (HIFU) Technique for Patients With Unresectable Pancreatic Tumor Treatment (PULS) (PULS)

Non-Resectable Pancreas Carcinoma

France
Xuanwu Hospital, Beijing

Recruiting

Transcranial Alternating Current Stimulation (tACS) on Serotonin-1A Receptor in Depression

Major Depressive Disorder

China
Sohag University

Recruiting

Assessment of Serum Levels of Janus Kinase 1 and 2 in Patients With Cholinergic Urticaria

Cholinergic Urticaria

Egypt
MicroPort NeuroTech Co., Ltd.

Recruiting

A PROSPECTIVE, MULTICENTER, SINGLE-ARM TRIAL FOR THE NEW SIZES OF BRIDGE STENTS FOR VERTEBRAL ARTERY STENOSIS: Bridge-MAX

Brain Diseases | Vertebral Artery Stenosis | Vertebral Artery Thrombosis

China
Marc Dall'Era, MD
National Cancer Institute (NCI)

Recruiting

Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer

Localized Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8

United States
Diakonhjemmet Hospital
Oslo University Hospital; University Hospital, Akershus

Recruiting

The Hip Fracture Surgical Approach Trial (HIFSAT)

Hip Fracture | Femoral Neck Fracture

Norway
Lantern Pharma Inc.

Recruiting

A Study of LP-284 in Relapsed or Refractory Lymphomas and Solid Tumors

Advanced Solid Tumor | Relapsed or Refractory Lymphomas

United States
Faculdade de Motricidade Humana
University of Sao Paulo; Coordenação de Aperfeiçoamento de Pessoal de Nível...

Recruiting

Influence of Hypoxic, Normobaric and Hypobaric Training on the Immunometabolism of Post-covid-19 Athletes

Hypoventilation | Normoxia | Normobaric Hypoxia

Portugal
Martin Dichgans

Recruiting

High Frequency Imaging in Cerebral Amyloid Angiopathy (HIFI-CAA)

Cerebral Amyloid Angiopathy

Germany
ProMis Neurosciences, Inc

Recruiting

A Phase 1a Study of PMN310 In Healthy Volunteers

Healthy Participants

United States
University Hospital, Tours

Recruiting

Weaning Protocol for High-flow Nasal Oxygen Therapy in Intensive Care (HiFloWEAN)

Acute Hypoxemic Respiratory Failure | High-flow Nasal Oxygen Therapy

France
Cardarelli Hospital

Recruiting

Impact of High Flow Therapy on Complications Related to Airway Stenting (HiSTENT)

Airway Obstruction | Respiratory Infection | Mucus; Plug

Italy
Children's National Research Institute

Recruiting

Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

Cerebral Palsy, Dyskinetic | Secondary Dystonia

United States
German Society for Pediatric Oncology and Hematology...
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

Nivolumab in Children and Adults With Nasopharyngeal Carcinoma (NPC-Nivo)

Nasopharyngeal Carcinoma | Nasopharyngeal Cancer | Nasopharynx Cancer | Nasopharyngeal Neoplasms

Germany
BioRay Pharmaceutical Co., Ltd.

Not yet recruiting

Clinical Study of 1A46 Drug Substance

Advanced Malignancies

China
Omeicos Therapeutics GmbH

Recruiting

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION) (PMD-OPTION)

Primary Mitochondrial Disease

Germany, Italy
Seoul National University Hospital
Jeysis Medical

Not yet recruiting

Safety & Efficacy of Non-Invasive Procedures Using Ultrasound-Guided HIFU 'Sonotrip V20' in Symptomatic Uterine Fibroids

Myoma;Uterus
Qilu Hospital of Shandong University

Recruiting

Tryptophan Metabolites in Pediatric Migraine

Migraine in Children

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

Phase 1a Study in Healthy Participants

Healthy
Arkansas Colleges of Health Education

Recruiting

High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners (SHIFT-AR)

Stroke | Multiple Sclerosis | Brain Injuries | Parkinson Disease | Spinal Cord Injuries | Neurologic Disorder | Poliomyelitis | Spina Bifida

United States
Hasten Biopharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Mexartan Potassium Tablets (AZL-M) and Calcium Channel Blockers (CCB) in the Treatment of Adults With Essential Hypertension in Chinese Population: a National Multicenter, Prospective, Observational Study

Essential Hypertension

China
Fred Hutchinson Cancer Center
Faron Pharmaceuticals Ltd

Not yet recruiting

Interferon-Beta-1a (FP-1201) to Prevent Toxicities After CD19-Directed CAR T-Cell Therapy

Recurrent Mantle Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Refractory Mantle Cell Lymphoma

United States
NiKang Therapeutics, Inc.
Pfizer

Recruiting

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Neoplasms | Kidney Cancer | Kidney Neoplasms | Carcinoma, Renal Cell | Urologic Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Kidney Diseases | Urologic Diseases | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Clear Cell Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Recurrent... and other conditions

United States
Lantern Pharma Inc.

Recruiting

Study of LP-184 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

United States
Theraclion

Recruiting

Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study (VEINRESET)

Chronic Venous Insufficiency

United States, Austria, Czechia
RenJi Hospital

Recruiting

Combination of RC48 and Tislelizumab for Renal Preservation in High-risk UTUC Patients

Upper Urinary Tract Urothelial Carcinoma | Kidney Preservation | HER-2 ADC | PD-1antibody

China

Search clinical trials for: HIF 1a

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