Search clinical trials for: HPV-driven oropharynx cancer

Total 86385 results

UNICANCER

Active, not recruiting

Feasibility and Tolerance of Nivolumab Neoadjuvant Immunotherapy in High Risk HPV Driven Oropharynx Cancer (IMMUNEBOOST)

Oropharynx Cancer

France
Wake Forest University Health Sciences
InnoTech Precision Medicine

Not yet recruiting

Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer

Oropharyngeal Squamous Cell Carcinoma | Human Papillomavirus Infection

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

United States
Theravectys S.A.

Not yet recruiting

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Omar Mahmoud

Not yet recruiting

Dose Adjusted Chemoradiotherapy in HPV-Associated Oropharynx Cancer of the Elderly ((DACHOC-E))

Frailty | Oropharynx Cancer
Royal North Shore Hospital

Not yet recruiting

De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE) (DE-RADIATE)

HPV Positive Oropharyngeal Squamous Cell Carcinoma

Australia
H. Lee Moffitt Cancer Center and Research Institute
National Institutes of Health (NIH)

Recruiting

Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC) (BASH OPC)

Oropharyngeal Cancer | HPV-Related Carcinoma

United States
Inhibrx, Inc.

Recruiting

INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC

Head and Neck Squamous Cell Carcinoma (HNSCC)

United States
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Sparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia

Head and Neck Cancer | Xerostomia | Oropharynx Cancer

United States
Emory University
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma

Oropharynx Cancer, Stage I

United States
University of Michigan Rogel Cancer Center

Recruiting

Trial of Individualized Adaptive RT in HPV-related High Risk Oropharynx Cancer (ARTHOUSE)

Oropharynx Cancer | HPV-Related Carcinoma

United States
National Cancer Institute (NCI)

Not yet recruiting

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Squamous Cell Carcinoma of the Head and Neck | Drug Therapy | Oropharynx | Human Papillomavirus Viruses | Cancer Vaccine

United States
Sun Yat-sen University

Recruiting

SBRT Followed by Neoadjuvant Chemoimmunotherapy of Sindilizumab Plus Docetaxel and Cisplatin for Locoregionally Advanced Squamous Carcinoma of Oral Cavity and Oropharynx

SBRT

China
Viome

Not yet recruiting

Validity of Viome's Oral/Throat Cancer Test

Oropharyngeal Squamous Cell Carcinoma | Oral Squamous Cell Carcinoma | Oral and Throat Cancer
Fudan University

Recruiting

PD-1 Inhibitor Based Induction Chemotherapy Followed by De-escalation Protocols in OPSCC

Oropharyngeal Cancer

China
National Cancer Institute, Egypt

Not yet recruiting

Standard Pulsed Radiofrequency Versus Supervoltage Pulsed Radiofrequency Glossopharyngeal Nerve in Oropharyngeal Cancer Pain

Pain | Oropharyngeal Cancer | Pulsed Radiofrequency | Super Voltage Pulsed Radiofrequency | Glossopharyngeal Nerve

Egypt
University Medical Center Groningen

Recruiting

Real-time Targeted Fluorescence Endoscopy for Detection of the Primary Cancer Lesion in Patients With a Metastasis of Unknown Primary Tumor in the Head and Neck (REFLECT)

Oropharynx Cancer | Unknown Primary Tumors

Netherlands
University of Maryland, Baltimore

Recruiting

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) (SAVAL)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Oropharynx Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Oropharynx Squamous Cell Carcinoma

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III... and other conditions
University of California, San Francisco
National Institute of Dental and Craniofacial Research (NIDCR)

Not yet recruiting

People Living With HIV, Oral and Oropharyngeal Cancer, and Health Equity

HIV Infections | Oropharyngeal Squamous Cell Carcinoma | Oral Squamous Cell Carcinoma

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)

Head and Neck Cancer

Taiwan, United States, Korea, Republic of, Spain, Belgium, Israel
University Medical Center Groningen

Recruiting

Immunological Function After Radiation With Either Proton or Photon Therapy (PRO-IMMUNO)

Head and Neck Cancer | Oropharynx Cancer | Larynx Cancer | HNSCC | Hypopharynx Cancer

Netherlands
Peking University Hospital of Stomatology

Recruiting

Neoadjuvant Tislelizumab Plus Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer (NeoSPOT)

Oropharyngeal Squamous Cell Carcinoma | Oral Squamous Cell Carcinoma

China
Gustave Roussy, Cancer Campus, Grand Paris
LinKinVax

Recruiting

Therapeutic Vaccine in Patients With Human Papillomavirus HPV-positive Oropharyngeal Cancer (HPVDCVax)

Head and Neck Carcinoma | Adult Disease

France
National Cancer Institute (NCI)

Recruiting

Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma (SCC)

United States
Washington University School of Medicine
Eli Lilly and Company

Recruiting

Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma (Rambro2)

Recurrent Head and Neck Carcinoma | Recurrent Head and Neck Squamous Cell Carcinoma | HNSCC | Recurrent Head and Neck Cancer | Metastatic Head and Neck Cancer | Metastatic Head-and-neck Squamous-cell Carcinoma

United States
TScan Therapeutics, Inc.

Recruiting

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Melanoma | Cervical Cancer | Head and Neck Cancer | HPV-Related Malignancy | Ovarian Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Non-small Cell Carcinoma | HPV - Anogenital Human Papilloma Virus Infection | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma and other conditions

United States
EpicentRx, Inc.

Recruiting

RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer (KEVLARx)

Oral Mucositis

United States
University of Virginia

Not yet recruiting

HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma (HN001)

Squamous Cell Carcinoma of the Oropharynx

United States
Royal Marsden NHS Foundation Trust

Recruiting

Single and Combined Modality Trans-Oral Robotic Surgery in Early Oropharyngeal Cancer (SCORE)

Cancer Head Neck

United Kingdom
Regina Elena Cancer Institute
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Weizmann Institute... and other collaborators

Recruiting

Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus

Liquid Biopsy | Squamous Cell Carcinoma of the Oropharynx | Lymph Node Metastasis | Carcinomas of Unknown Primary Site | High-risk Human Papillomavirus Infection | Occult Tumor of the Head and Neck Area

Italy
University of Michigan Rogel Cancer Center

Recruiting

A Phase II Study for p16+ Oropharyngeal Cancer PerSonalized De-escalation Treatment at University of MIchigan (CuSToMIze)

Oropharyngeal Cancer | Squamous Cell Carcinoma of the Oropharynx

United States
Geisinger Clinic

Recruiting

Liposomal Bupivacaine and Transoral Robotic Surgery

Post Operative Pain | Oropharyngeal Cancer | Dysphagia, Oropharyngeal | Transoral Robotic Surgery

United States
University of Miami

Not yet recruiting

Feasibility of Adaptive Radiation Therapy for Human-papilloma Virus-positive Oropharyngeal Cancer Patients on MRIdian Linac (OPC-V)

Oropharynx Cancer

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

Oropharyngeal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Michael K. Gibson

Recruiting

pBI-11 & TA-HPV (With Pembrolizumab as Treatment for Patients w/Advanced, PD-L1 CPS≥1, hrHPV+ Oropharyngeal Cancer

Recurrent Oropharyngeal Carcinoma | Metastatic Oropharyngeal Carcinoma

United States
Fox Chase Cancer Center
Cardinal Health

Recruiting

Lymphoscintigraphy Directed Elective Neck Radiation for p16+ Favorable Risk Oropharynx Cancer

Oropharynx Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors

Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer | Hypopharynx Cancer

United States
Medical University of South Carolina
National Cancer Institute (NCI)

Recruiting

Multi-Site Trial of Navigation vs Treatment as Usual for Delays in Starting Adjuvant Therapy (ENDURE)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer

United States
HRYZ Biotech Co.

Recruiting

HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor

Cervical Cancer | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | Anal Carcinoma | Vagina Tumor | Carcinoma of Penis | Carcinoma of Vulva

China
University of California, San Diego

Recruiting

Neoadjuvant Immunoradiotherapy With Evorpacept and Pembrolizumab in HPVOPC (Human Papilloma Virus Oropharynx Cancer)

Oropharynx Cancer

United States
The Institute of Molecular and Translational Medicine...
University Hospital Olomouc; Cancer Research Czech Republic

Recruiting

Role of Liquid Biopsies in HPV-associated Cancer Treatment Monitoring

Cervical Cancer | Oropharyngeal Cancer | Human Papillomavirus Infection | Cervical Dysplasia

Czechia
Institut Claudius Regaud

Recruiting

Evaluation of the Benefit of a New Surgical Procedure According to IDEAL Recommendations for ORL Cancer Patients: the External Pudendal Flap Used as a New Free Flap for Oral Cavity/Oropharyngeal Reconstruction to Limit Donor Site Sequelae (LAMBEAU STEPA)

Head and Neck Cancer | Oropharynx Cancer | Oral Cavity Cancer

France
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage IV Hypopharyngeal Carcinoma AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Stage... and other conditions

United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer. (Ronco-Onco)

Snoring | Sleep Apnea | Oral Cancer | Oral Squamous Cell Carcinoma | Pharynx Cancer

Canada
Abramson Cancer Center at Penn Medicine

Recruiting

Shortened Course Adjuvant Radiotherapy Following TORS

Oropharyngeal Squamous Cell Carcinoma

United States
Rigshospitalet, Denmark
The Novo Nordic Foundation

Recruiting

Surgeon-performed Outpatient Transoral and Transcervical Ultrasound of the Oropharynx (SPOT-US)

Oropharynx Cancer | Tonsil Cancer | Tonsil Hypertrophy | Base of the Tongue Tumor | Tonsil Ulcer | Tonsil Neoplasm | Tonsil Lymphoma | Base of Tongue Carcinoma

Denmark
Christian Hinrichs

Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Cervical Cancer | HPV-Related Malignancy | Metastatic Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
Region Skane

Recruiting

Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV) (MER-HPV)

Oropharynx Squamous Cell Carcinoma

Sweden
Christian Hinrichs
National Cancer Institute (NCI)

Not yet recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Cervical Cancer | HPV-Related Malignancy | Vulvar Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Associated Cervical Carcinoma | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States

Search clinical trials for: HPV-driven oropharynx cancer

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