Search clinical trials for: Healthy moderately heavy smokers

Total 30194 results

Philip Diaz

Completed

Green Tea Anticancer Mechanisms in Smokers

Cancer

United States
National Institute on Drug Abuse (NIDA)

Completed

Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smokers and in Heavy and Light Situational Smokers

Nicotine Addiction

United States
GlaxoSmithKline

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of GSK2256294 in Healthy Volunteers, and Single and Repeat Doses of GSK2256294 in Adult Male Moderately Obese Smokers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Helsinn Healthcare SA
Celerion

Completed

Study to Evaluate the Food Effect of Single-dose Bioavailability of Pracinostat in Healthy Adult Subjects (HVFE)

Healthy Volunteers | Non-smokers | Moderate to Heavy Smokers

United States
Pierre Fabre Medicament

Completed

Assessment of V0018 1.5 mg Effect on Craving

Smoking

France
Assiut University

Not yet recruiting

LDCT Chest In Assessment Of Apparently Healthy Smokers

Smoking
International Vaccine Institute
Massachusetts General Hospital; EuBiologics Co.,Ltd

Recruiting

Dose Escalation Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Healthy Adults

Cholera Vaccination Reaction

Korea, Republic of
Alfred Chung, MD
AbbVie; Janssen Pharmaceuticals

Recruiting

Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)

AL Amyloidosis | Light Chain (AL) Amyloidosis | Systemic Light Chain Disease

United States
University of Washington

Recruiting

Tafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma | Grade 3b Follicular Lymphoma

United States
University of Washington
Incyte Corporation

Recruiting

Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States
University of Oklahoma
National Institute on Minority Health and Health Disparities (NIMHD)

Not yet recruiting

A Culturally Tailored Smartphone Application for African American Smokers (HC)

Smoking Cessation
National Cancer Institute (NCI)

Recruiting

Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers

Cigarette Smoking-Related Carcinoma

United States
M.D. Anderson Cancer Center

Recruiting

Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study

Diffuse Large B-Cell Lymphoma

United States
Goranka Radmilović

Recruiting

The Effect of Orally Administered L- Arginine on Quadriceps Strenght in Healthy Smokers

Spirometry | Qadriceps Muscle

Croatia
Asan Medical Center

Not yet recruiting

Analysis of the Microbiome in the Healthy Smokers and COPD Patients

Pulmonary Disease, Chronic Obstructive | Microbiota

Korea, Republic of
Abramson Cancer Center at Penn Medicine
National Cancer Institute (NCI); New York University; Stanford University

Recruiting

GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments

Smoking | Smoking, Tobacco | Smoking, Cigarette

United States
The Cleveland Clinic

Recruiting

Peripheral Blood Mononuclear Cells Response In Healthy Controls, Heavy Drinkers, and Patients With Alcoholic Hepatitis

Alcoholic Hepatitis

United States
University of Oulu
Lapland Central Hospital Rovaniemi Finland

Completed

Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers (EFFECT)

Smoking Cessation | Electronic Cigarette

Finland
AstraZeneca

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of AZD7503 in Japanese Healthy Participants.

Heathy Participants

Japan
Research Center Borstel
Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures and other collaborators

Completed

SAW Lung Microbiome Study in Smokers and Never-smokers

Smoking Cessation | Healthy | Microbial Colonization | Chronic Obstructive Pulmonary Disease (COPD)

Germany
University of Southern Denmark
Team Denmark

Completed

Effects of Heavy-load Resistance Training

Healthy

Denmark
Imperial College London
Duska Scientific Co.

Completed

ATP/AMP Challenge in Healthy Non-smokers, Smokers, Patients With Asthma, and Patients With Chronic Obstructive Pulmonary Disease (COPD)

Smoking | Asthma | COPD

United Kingdom
Imperial College London

Withdrawn

Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
HALEON

Completed

A Bioequivalence Study of 21 Milligram (mg) Nicotine Transdermal Patches (NicoDerm CQ, GlaxoSmithKline [GSK] Dungarvan) Compared to the Current Marketed 21 mg Nicotine Transdermal Patches (NicoDerm CQ, Alza) in Healthy Adult Smokers

Tobacco Use Disorder

United States
Charite University, Berlin, Germany

Completed

Modification of Pavlovian and Instrumental Learning in Human Addiction

Healthy | Alcohol Use Disorder (Mild vs. Moderate to Heavy)

Germany
AbbVie

Completed

A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State

Systemic Lupus Erythematosus (SLE)

United States, Argentina, Australia, Bulgaria, China, Colombia, Germany, Hungary, Italy, Japan, Korea, Republic of, Mexico, New Zealand, Poland, Puerto Rico, Spain, Taiwan, United Kingdom
Achieve Life Sciences

Completed

Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers

Smoking Cessation

Portugal
AbbVie

Completed

A Study to Investigate the Safety and Efficacy of Elsubrutinib and Upadacitinib Given Alone or in Combination in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) (SLEek)

Systemic Lupus Erythematosus (SLE)

United States, Argentina, Australia, Bulgaria, Canada, China, Colombia, France, Germany, Hungary, Italy, Japan, Korea, Republic of, Mexico, Netherlands, New Zealand, Poland, Puerto Rico, Spain, Taiwan, United Kingdom
National Cancer Institute (NCI)

Completed

Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers

Cigarette Smoking-Related Carcinoma | Tobacco-Related Carcinoma

United States
Imperial Brands PLC
Nerudia Ltd

Completed

An Exploratory PET-study of Deposition, Disposition and Brain Uptake of [11C]Nicotine After Inhalation of 2 Nicotine Formulations Via the myBluTM E-cigarette in Smokers

Healthy Volunteers

Sweden
Achieve Life Sciences

Completed

Study to Evaluate Electrocardiographic Effects of Therapeutic & Supratherapeutic Doses of Cytisinicline in Healthy Smokers

Smoking Cessation

Portugal
Shenzhen Smoore Technology Limited

Withdrawn

The Effectiveness of Using E-Cigarettes for Smoking Cessation and Decreasing Risk of Diseases Among Heavy Smokers

Smoking Cessation

China
Brown University
National Institute on Drug Abuse (NIDA)

Active, not recruiting

A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers

Smoking Cessation | Obesity

United States
Philip Morris Products S.A.

Completed

A Smoking Cessation Study to Understand the Biological and Functional Changes After One Year of Smoking Cessation (RIBESC)

Cigarette Smoking

United States, Poland, Germany, Japan, United Kingdom
Philip Morris Products S.A.

Completed

Evaluation of Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2 for 26 Weeks

Smoking

United States
Prof Stig Larsen
Tine

Completed

Estimation of Minimum Efficacy Daily Dose of Jarlsberg Cheese

Diabetes | Cancer | Liver Disease | Heathy Women | Pre Menopausal Age | Exlution Criteria: Gastrointestinal Disorder | Kidney Disorder

Norway
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Effect of Black Raspberry Phytochemicals on Oral Microbiome in Current Smokers and Non-smokers

Tobacco Use Disorder | Healthy Subject

United States
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouch 1.0 Compared to Velo® Ice Cool and Zyn® Cool Mint Mini Dry in Healthy Smokers

Smoking | Nicotine

United Kingdom
University of Central Florida

Completed

The Duration of Effects of Massage in Healthy Participants

Healthy | Massage | Pressure Pain Threshold

United States
GlaxoSmithKline

Completed

Study to Assess the Immunogenicity and Safety of GSK's Investigational Vaccine (GSK3277511A) When Given to Healthy Smokers and Ex-smokers After Administration of Shingrix Vaccine

Respiratory Disorders

France, Estonia, Spain, Finland, Italy
Engage Therapeutics, Inc.
Clinilabs, Inc.

Completed

Pharmacokinetic Study Evaluating Staccato® Alprazolam 1 mg Inhaler in Smokers Versus Non-Smokers

Healthy

United States
DR. MALA KHAN
Bangladesh Reference Institute of Chemical Measurements (BRICM)

Completed

Virucidal Effect of PVP-I on COVID-19 and as Well as Safety of Its Application on Nasopharynx & Oropharynx (COVID-19)

Efficacy, Self | Effect of Drug | Virus Infection, RNA

Bangladesh
Bulent Ecevit University

Completed

miRNAs in Periodontal Disease

Periodontitis | Periodontal Diseases | Gingivitis

Turkey
University of California, San Francisco
National Institute on Drug Abuse (NIDA); University of California, Davis; Chinese... and other collaborators

Completed

A Family-Focused Intervention for Asian American Male Smokers

Smoking Cessation | Health Behavior | Family

United States
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Varenicline for Smoking Cessation in Heavy Drinking Smokers

Smoking | Nicotine Dependence | Heavy Drinking
UCB Biopharma S.P.R.L.

Terminated

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Impaired Hepatic Function | Healthy Study Participants

United States
Fontem Ventures BV

Completed

A Study to Assess Tobacco-related Biomarkers of Exposure in Smokers Using myBlu E-cigarettes

Healthy Volunteers

United States
Juul Labs, Inc.

Completed

Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers

Tobacco Use | Tobacco Smoking | Nicotine Dependence | Nicotine Dependence, Cigarettes

New Zealand
Fontem US LLC
Fontem Ventures BV

Completed

A Study to Evaluate Nicotine Uptake and Biomarkers in Smokers Using mybluTM Electronic Cigarettes

Healthy Volunteers

United States
Fontem US LLC
Fontem Ventures BV

Completed

A Study to Evaluate Nicotine Uptake and Biomarkers in Adult Smokers Using mybluTM Electronic Cigarettes

Healthy Volunteers

United States

Search clinical trials for: Healthy moderately heavy smokers

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