Search clinical trials for: High-Risk prostate cancer

Total 87602 results

University of Maryland, Baltimore
Janssen Scientific Affairs, LLC

Recruiting

High-Risk Metachronous Oligometastatic Prostate Cancer Trial (KNIGHTS)

Prostate Cancer | Oligometastatic Disease

United States
Comprehensive Cancer Centre The Netherlands

Recruiting

High-Risk prostatE Cancer radiatiOn Versus surgERy (RECOVER)

Prostate Cancer | Prostate Adenocarcinoma

Netherlands
VA Office of Research and Development

Not yet recruiting

A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss (SNARE)

High-Risk Prostate Cancer

United States
Rana McKay, MD
University of California, San Diego; AstraZeneca

Recruiting

Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With BRCA1/2 Gene Alterations (NePtune)

Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Adenocarcinoma | High-Risk Cancer

United States
Zhujiang Hospital

Recruiting

An Evaluation of the Efficacy and Safety of Apalutamide as Neoadjuvant Endocrine Therapy in High-Risk and Oligometastatic Prostate Cancer

High-Risk and Oligometastatic Prostate Cancer

China
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) (CYCLONE 3)

Urogenital Neoplasms | Prostatic Neoplasms | Neoplasm Metastasis | Enzyme Inhibitors | Antineoplastic Agents | Hormones | Physiological Effects of Drugs | Antineoplastic Agents, Hormonal | Androgens | Hormones, Hormone Substitutes, and Hormone Antagonists | Abiraterone Acetate | Steroid Synthesis Inhibitors | Cytochrome... and other conditions

China, Canada, France, United States, Australia, Czechia, Hungary, Spain, Germany, Japan, Taiwan, Netherlands, Turkey, Mexico, Belgium, Korea, Republic of, Argentina, Romania, United Kingdom, Italy, Israel, Brazil, Poland, Greece
Aragon Pharmaceuticals, Inc.

Active, not recruiting

An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS

Prostatic Neoplasms

United States, France, Poland, Taiwan, Ukraine, United Kingdom, China, Belgium, Germany, Spain, Israel, Mexico, Malaysia, Romania, Turkey, Canada, Netherlands, Korea, Republic of, Brazil, Russian Federation, Argentina, Sweden, Czechia
University Health Network, Toronto
Princess Margaret Hospital, Canada

Completed

Fiducial Localization and Individualized Radiotherapy -Prostate Cancer (FLIP)

Prostate Cancer

Canada
RWTH Aachen University

Terminated

Neoadjuvant Chemotherapy With Cabazitaxel (CLUBNET)

High-Risk Cancer

Germany
Benaroya Research Institute
Genentech, Inc.

Completed

Bevacizumab With Hormonal and Radiotherapy for High-Risk Prostate Cancer

Prostate Cancer

United States
Institut de Cancérologie de Lorraine

Not yet recruiting

Adherence to Oral Therapies in Advanced Breast and Prostate Cancers (AdOTAC)

Breast Cancer | Prostate Cancer

France
Peking University Third Hospital
Bayer

Not yet recruiting

Efficacy and Safety of Darolutamide in Combination With Androgen-Deprivation Therapy in Prostate Cancer Patients With Lymph Node-positive After Radical Prostatectomy: A Prospective Observational Cohort Study

Prostate Cancer

China
Case Comprehensive Cancer Center

Not yet recruiting

Developing Inclusive Support and Intervention for Spanish-speaking Latiné Prostate Cancer Survivors

Prostate Cancer

United States
Clinton Bahler
On Target Laboratories

Not yet recruiting

CYTALUX™for the Intraoperative Imaging of Prostate Cancer

Prostate Cancer

United States
Ning Xu
The First Affiliated Hospital of Nanchang University; Zhongshan Hospital Xiamen... and other collaborators

Not yet recruiting

Posterior Extra-fascial RARP in Intermediate or High Risk Prostate Cancer

Prostate Cancer | Surgical Procedure, Unspecified
Odense University Hospital
Zealand University Hospital; Rigshospitalet, Denmark; Sygehus Lillebaelt

Recruiting

A Multi-center Investigation of Family Health.

Breast Cancer | Hematologic Neoplasms | Colorectal Cancer | Prostate Cancer | Caregivers

Denmark
Medical University of Vienna
Lund University; Ziekenhuis Netwerk Antwerpen (ZNA); St. Antonius Hospital; Azienda... and other collaborators

Not yet recruiting

Outcomes of Local Treatment for Oligometastatic Prostate Cancer Diagnosed Using PSMA PET Imaging: OLIGOMET Study (OLIGOMET)

Prostate Cancer | Prostate Cancer Metastatic | Oligometastasis | Prostate Neoplasm | Oligometastatic Disease | Prostate Cancer Metastatic to Bone
Paul Viscuse

Not yet recruiting

Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)

Metastatic Prostate Cancer | Castrate Sensitive Prostate Cancer

United States
Osamu Ukimura

Recruiting

Targeted Microwave Tissue Coagulation for Prostate Cancer (MicroPro2)

Prostate Cancer

Japan
European Association of Urology Research Foundation
National Cancer Institute (NCI); UMC Utrecht; Erasmus Medical Center; University... and other collaborators

Not yet recruiting

Prostate Cancer Awareness and Initiative for Screening in the European Union (PRAISE-U)

Prostate Cancer
Institute of Cancer Research, United Kingdom

Recruiting

Microbiome Molecular Charaterisation (MMC)

Prostate Cancer

United Kingdom
University of Southern California
National Cancer Institute (NCI)

Not yet recruiting

Access to Genetic Testing in Underserved Patients With Cancer

Malignant Solid Neoplasm | Breast Carcinoma | Metastatic Prostate Carcinoma | Ovarian Carcinoma | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Pancreatic Exocrine Neoplasm | Stage IVB Prostate Cancer American Joint Committee on Cancer v8

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

M9466 as Single Agent or in Combination With Tuvusertib in Advanced Solid Tumors (DDRiver 501)

Advanced Solid Tumor

United States, Germany
First Affiliated Hospital of Chongqing Medical...

Recruiting

99mTc-QULIC-5-P1 SPECT Imaging in Patients With Prostate Cancer

PSMA | Prostate Cancer Stage | SPECT

China
University Hospital Padova

Recruiting

Can Needle Size Improve Cancer Detection Rate of Transperineal MRI Target Prostate Biopsy Without Affecting Side Effects? (TARGET)

Prostate Cancer Diagnosis

Italy
University Health Network, Toronto

Not yet recruiting

Adaptive Moderately Hypofractionated Post Operative Radiotherapy (AMPORA)

Post-Operative Prostate Cancer
Lionel.D.Lewis, MD
Dartmouth Cancer Center

Not yet recruiting

HCQ in Resectable Localized Prostate Cancer

Resectable Localized Prostate Cancer
Nazmy Edward Seif

Recruiting

Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy

Renal Impairment | Prostate Cancer | Surgery | Bladder Cancer | Renal Injury, Acute

Egypt
Maastricht University Medical Center
Jessa Hospital

Not yet recruiting

The Impact of Physical Activity Versus Dietary Energy Restriction on Tumour and Muscle Protein Synthesis in Prostate Cancer Patients (DIRECT)

Cancer of Prostate
Swiss Group for Clinical Cancer Research

Not yet recruiting

Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Metastatic Castration-resistant Prostate Cancer

Switzerland
University of Florida
EDAP-TMS Focal One

Not yet recruiting

High Intensity Focused Ultrasound in Prostate Cancer

Prostate Cancer

United States
Chang Gung Memorial Hospital

Recruiting

Comparing Bp-MRI and Mp-MRI for Prostate Cancer Screening Accuracy

Prostate Cancer | Magnetic Resonance Imaging | Randomized Controlled Trial

Taiwan
Fusion Pharmaceuticals Inc.

Recruiting

FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) (AlphaBreak)

Metastatic Castration-resistant Prostate Cancer

United States
Twinpig Biolab, Inc.

Not yet recruiting

Clinical Trial of TB511 in Advanced Solid Tumors

Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Prostate Cancer
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Colorectal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Prostate Cancer | Gastric Adenocarcinoma | Cholangiocarcinoma | Triple Negative Breast Cancer | Endometrial Adenocarcinoma | Appendiceal Adenocarcinoma
IRCCS San Raffaele

Recruiting

Observational Study of Patients Who Underwent Diagnostic Investigation (Prostate Biopsy) and/or Radical Prostatectomy Surgery.

Prostate Cancer

Italy
Oslo University Hospital
University Hospital, Akershus

Recruiting

Preoperative PSMA PET/CT as Triage for ePLND in Patients Scheduled for RALP (PrePSMA) (PrePSMA)

Prostate Cancer

Norway
Complement Theory Inc.

Recruiting

A Randomised Controlled Trial to Evaluate the Impact of Complement Theory's Live 1:1 Exercise Coaching and Personalised Digital Application on Cancer Survivors' Cost of Care

Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Other Cancer

United States
University College, London
University College London Hospitals

Recruiting

Study to Evaluate a New Method to Detect Residual Tumours During Surgery for Prostate Cancer Using Confocal Microscopy

Prostate Cancer

United Kingdom
NYU Langone Health

Recruiting

ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer

Prostate Cancer

United States
Adam S. Kibel, MD
National Cancer Institute (NCI)

Recruiting

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer (PRS)

Prostate Cancer | Polygenic Risk Score

United States
858 Therapeutics, Inc.

Recruiting

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies (ERADIC8)

Breast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Advanced or Metastatic Solid Tumors | ER+ Breast Cancer | Castrate Resistant Prostate Cancer | BRCA Mutation

United States
Debiopharm International SA

Recruiting

A Dose Finding Study of Debio 4228 in Participants With Locally Advanced/Metastatic Prostate Cancer

Prostate Cancer

United States
Qian Qin
Janssen, LP; UT Southwestern Comprehensive Cancer Center

Not yet recruiting

Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations (HARMONY)

BRCA1 Gene Mutation | BRCA2 Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | CHEK2 Gene Mutation | FANCA Gene Mutation | RAD51B Gene Mutation | RAD54L Gene Mutation | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Deleterious HRR Gene Mutation
University of Miami

Not yet recruiting

PSMA-Directed Para-Aortic Radiation Therapy for Oligorecurrent Prostate Cancer (OCEAN)

Prostate Cancer | Prostate Adenocarcinoma | Hormone Sensitive Prostate Cancer

United States
Robert Bok, MD, PhD
National Cancer Institute (NCI)

Not yet recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer

Prostate Cancer

United States
Peking University First Hospital

Recruiting

Comparison of MRI Artificial Intelligence-guided cTB Versus Routine cTB in Prostate Cancer Diagnosis

Prostate Cancer

China
University Hospital, Essen
Bristol-Myers Squibb; Advanced Accelerator Applications

Not yet recruiting

Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer (NEPI)

Very High Risk Prostate Carcinoma

Germany
Norroy Bioscience Co., LTD

Recruiting

Pharmacokinetics, Biodistribution, Radiation Dose and Safety Study of 68Ga-NYM032 in Patients

Prostate Cancer

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Not yet recruiting

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization ((SEEtoTREAT))

Prostate Cancer | Advanced Cancer

Search clinical trials for: High-Risk prostate cancer

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