Search clinical trials for: Hydromorphone hydrochloride Oral Osmotic System

Total 257770 results

Johnson & Johnson Pharmaceutical Research & Development...

Completed

An Efficacy and Safety Study of Oral Osmotic Therapeutic System (OROS) Hydromorphone Hydrochloride (HCl) in Participants With Cancer Related Pain

Pain

China
Johnson & Johnson Taiwan Ltd

Terminated

A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer Pain

Cancer Pain
Janssen Korea, Ltd., Korea

Completed

An Efficacy and Safety Study of Hydromorphone Hydrochloride (HCl) Oral Osmotic System (OROS) in the Reduction of Breakthrough Pain Medication Frequency in Participants With Cancer

Pain | Cancer
Fujian Cancer Hospital

Not yet recruiting

IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration

Cancer Pain

China
University of California, Davis

Recruiting

Multimodal Analgesia Effect on Post Surgical Patient

Surgery | Obesity, Morbid | Bariatric Surgery Candidate

United States
Henrik Wiggers
Danish Heart Foundation; Danish Council for Independent Research; The Danish... and other collaborators

Recruiting

DANHEART (H-HeFT and Met-HeFT) (DANHEART)

Heart Failure | Diabetes

Denmark
Xian-Janssen Pharmaceutical Ltd.

Completed

A Long Term Post-Marketing Study on the EffIcacy and Safety of Osmotic Release Oral System (OROS) Methylphenidate on the Cognitive Functions of Attention Deficit Hyperactivity Disorder (ADHD) Participants

Attention Deficit Hyperactivity Disorder (ADHD)

China
Xian-Janssen Pharmaceutical Ltd.

Completed

A Pharmacokinetic and Safety Study of Osmotic Release Oral System (OROS) Hydromorphone in Non-Opioid Tolerant Chinese Participants With Cancer

Pain

China
Janssen Korea, Ltd., Korea

Completed

An Efficacy and Safety Study of Osmotic Release Oral System (OROS) Methylphenidate in Participants With Attention Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Disorder With Hyperactivity
Janssen Korea, Ltd., Korea

Completed

An Efficacy and Safety Study of Hydromorphone Oral Osmotic System (OROS) in Korean Participants With Cancer Pain

Cancer Pain
Janssen Pharmaceutica

Terminated

Safety and Efficacy Study of Osmotic Release Oral System (OROS) Hydromorphone in Participants With Cancer Pain

Pain
Janssen Korea, Ltd., Korea

Completed

Study to Evaluate Effectiveness and Tolerability of OROS Hydromorphone for Cancer Pain Treatment in Korean Patients

Cancer Pain

Korea, Republic of
Janssen Korea, Ltd., Korea

Completed

An Efficacy Study of Osmotic Release Oral System (OROS) Methylphenidate in Participants With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Disorder With Hyperactivity
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

Adult Study / OROS Methylphenidate Hydrochloride (HCL) (OROS MPH) in Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Disorder With Hyperactivity
Eli Lilly and Company

Terminated

A Study in Attention Deficit Hyperactivity Disorder in Children and Adolescents (EMD)

Attention Deficit Hyperactivity Disorder

Netherlands, Sweden, Spain
Auburn University
National Institute on Drug Abuse (NIDA); Wayne State University

Not yet recruiting

Cannabinoids and Biological Reactivity to Stress (COBRAS)

Cannabis Use Disorder
Fujian Provincial Hospital
Fujian Maternity and Child Health Hospital; Fujian Children's Hospital

Not yet recruiting

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Behavior Problem
Ottawa Heart Institute Research Corporation

Not yet recruiting

Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension (MIDOH-HF-P)

Hypotension | Heart Failure With Reduced Ejection Fraction | LV Dysfunction
Ziauddin University

Not yet recruiting

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial (MROSF)

Oral Submucous Fibrosis

Pakistan
Brigham and Women's Hospital

Recruiting

Trazodone on OSA Endotypes

Obstructive Sleep Apnea

United States
AbbVie
Genmab

Recruiting

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma (EPCORE™FL-2)

Follicular Lymphoma (FL)

United States, Puerto Rico
NeuroRx, Inc.

Not yet recruiting

NRX-101 for Complicated Urinary Tract Infection (UTI) Including Pyelonephritis

Urinary Tract Infections | Pyelonephritis
National Cancer Institute, Egypt

Recruiting

Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain

Post-mastectomy Pain Syndrome

Egypt
Hairong Chen

Recruiting

Nalbuphine in ARDS Patients After Surgery

Acute Respiratory Distress Syndrome

China
Federico II University

Recruiting

Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth Syndrome

Burning Mouth Syndrome

Italy
Pouya Azar

Recruiting

Symptom-inhibited Fentanyl Induction (SIFI)

Opioid Use Disorder

Canada
University Hospital, Antwerp
Hasselt University; University Hospital, Ghent; AZ Sint-Jan AV; National MS Center... and other collaborators

Recruiting

Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary-progressive Multiple Sclerosis

Belgium
Qianfoshan Hospital

Not yet recruiting

Hydromorphone for Perioperative Analgesia in Lung Tumor Ablation Parallel Controlled

Pulmonary Nodule | Ablation
Institut Cancerologie de l'Ouest
Grünenthal GmbH

Not yet recruiting

Capsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral Neuropathy (CAPNEUCHIM)

Chemotherapy-induced Peripheral Neuropathy
Hospital San Carlos, Madrid

Recruiting

Amantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple Sclerosis (FETEM)

Multiple Sclerosis | Fatigue

Spain
Biogen

Recruiting

A Study to Assess Pregnancy Outcomes in Women Exposed to Diroximel Fumarate

Multiple Sclerosis

United States
Humanitas Clinical and Research Center
Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva

Recruiting

HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal Surgery (HISTAP)

Blood Pressure | Complication,Postoperative | Intraoperative Hypotension

Italy
Genmab
AbbVie

Recruiting

A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) (EPCORE DLBCL-2)

Diffuse Large B-Cell Lymphoma

Korea, Republic of, Spain, Japan, Israel, Australia, Poland, Netherlands, Sweden, Greece, Taiwan, Italy, Denmark, Switzerland, France, Bulgaria, Hungary, Austria, New Zealand, Czechia, Croatia, Belgium, Brazil, China, United States, Canada and more
Morten Steen Kvistholm Jensen
Odense University Hospital; Zealand University Hospital; Rigshospitalet, Denmark and other collaborators

Recruiting

Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy (TEMPO II)

Non-obstructive Hypertrophic Cardiomyopathy

Denmark
Rajshekhar Chakraborty, MD
Genentech, Inc.

Recruiting

Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

AL Amyloidosis

United States
Li Zhiming
Antengene Corporation

Recruiting

Selinexor Plus R-CHOP in High-risk GCB-subtype Diffuse Large B-Cell Lymphoma

DLBCL Germinal Center B-Cell Type

China
Mahidol University

Not yet recruiting

The Study of Efficacy and Safety of Generic Methylphenidate Prolong-released Comparison With Original

Adhd
Boston Children's Hospital

Recruiting

Oral Ketamine for Treatment of Vaso-Occlusive Pain

Vaso-occlusive Crisis

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Tucatinib Combined With Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8

United States
National Cancer Institute (NCI)

Recruiting

Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer

Extensive Stage Lung Small Cell Carcinoma | Limited Stage Lung Small Cell Carcinoma | Platinum-Resistant Lung Small Cell Carcinoma | Platinum-Sensitive Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States
Brigham and Women's Hospital

Recruiting

Atomoxetine and DAW2022 on OSA Severity

Obstructive Sleep Apnea

United States
Rehman Medical Institute - RMI

Recruiting

Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore Throat (Postbenas)

Sore Throat

Pakistan
Cairo University

Not yet recruiting

The Use of Tulsi Extract for The Management of Oral Mucositis in Head & Neck Cancer Patients Undergoing Radiotherapy

Stomatitis
Genmab
AbbVie

Recruiting

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma

United States, France, Israel, Korea, Republic of, Spain, Taiwan, Netherlands, Czechia, Japan, Hungary, Germany, Denmark
University Hospital, Akershus

Recruiting

Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients (SIM)

Pain Cancer

Norway
Tasly GeneNet Pharmaceuticals Co., Ltd

Recruiting

A Study to Assess the Efficacy and Safety of PXT3003 in Charcot-Marie-Tooth Type 1A

Charcot-Marie-Tooth Type 1A

China
DemeRx IB, Inc.
Hammersmith Medicines Research; ERT: Clinical Trial Technology Solutions; MAC...

Recruiting

A Study of Oral Ibogaine in Opioid Withdrawal

Opiate Withdrawal Syndrome

United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
AbbVie

Recruiting

Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
San Diego State University

Recruiting

Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences

Placebo | Naltrexone

United States
Angion Biomedica Corp
Quotient Sciences

Not yet recruiting

Study Developed to Evaluate the Effect of ANG-3777 on QT/QTc Interval

Healthy Volunteer

United States

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