Search clinical trials for: IgE antibody

Total 6190 results

The First Affiliated Hospital with Nanjing Medical...

Recruiting

A Clinical Study of Omalizumab in the Treatment of Allergic Asthma(ESSENCE) (ESSENCE)

Moderate to Severe Allergic Asthma

China
icometrix
Bristol-Myers Squibb; Charite University, Berlin, Germany; Hoffmann-La Roche; Ruhr... and other collaborators

Not yet recruiting

Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study. (RECLAIM)

Multiple Sclerosis | Clinically Isolated Syndrome | Radiologically Isolated Syndrome | NMO Spectrum Disorder | Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Guangzhou Excelmab Inc.

Recruiting

Safety and Efficacy of EX103 in Subjects With Relapsed/Refractory CD20-Positive Non-Hodgkin Lymphoma

CD20-positive Non-Hodgkin Lymphoma

China
Assistance Publique - Hôpitaux de Paris
Institut Pasteur

Recruiting

Repertoire and Properties of Anti-drug Antibodies Involved in Immediate Hypersensitivity in the Operating Room (MEDIREP)

Hypersensitivity, Immediate | Peri-operative Injury | Antibody Hypersensitivity | Antibiotic Allergy

France
United BioPharma

Recruiting

A Study to Evaluate the Pharmacodynamics, Pharmacokinetics, Safety, and Efficacy of UB-221 IV Infusion as an add-on Therapy in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

Taiwan
Emory University

Recruiting

Assessing Durable Antibody Response to HPV Vaccination

HPV

United States
United BioPharma

Not yet recruiting

Evaluating the Safety and Tolerability and Determining the PK and PD of Single Dose UB-221 in Chronic Spontaneous Urticaria

Chronic Idiopathic Urticaria
Xiqiang Dang
The First Affiliated Hospital of Anhui Medical University; LanZhou University; Guangzhou First People's Hospital and other collaborators

Recruiting

Multicenter Registry of Pediatric Lupus Nephritis in China

Children | Lupus Nephritis | Steroid | Immunosuppressive Treatment

China
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
Cairo University

Completed

Buzzy System Compared to Topical Anaesthesia During Infiltration Injection in Children.

Local Anaesthesia

Egypt
OHSU Knight Cancer Institute
Oregon Health and Science University

Terminated

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Primary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditions

United States
OHSU Knight Cancer Institute
Genentech, Inc.; Oregon Health and Science University

Withdrawn

SMMART Adaptive Clinical Treatment (ACT) Trial

Anatomic Stage III Breast Cancer AJCC v8 | Recurrent Ovarian Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Recurrent... and other conditions

United States
Rigshospitalet, Denmark
Zealand University Hospital; Novartis; Hvidovre University Hospital; Herlev Hospital

Active, not recruiting

Treatment With the Anti-IgE Monoclonal Antibody Omalizumab in Women With Asthma Undergoing Fertility Treatment. - A Proof of Concept Study. (PRO_ART)

Asthma | Infertility, Female

Denmark
Jemincare

Completed

Study of JYB1904 (an Anti-immunoglobulin E Antibody) in Healthy Chinese Subjects

Healthy

China
Cancer Research UK

Completed

Phase I Study of MOv18 IgE

Human Cancers

United Kingdom
Bristol-Myers Squibb

Terminated

A Dose Escalation and Combination Immunotherapy Study to Evaluate BMS-986226 Alone or in Combination With Nivolumab or Ipilimumab in Patients With Advanced Solid Tumors

Cancer | Neoplasm | Tumors | Malignancy

United States, Canada, Spain, Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Recurrent Hodgkin Lymphoma | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Aplastic Anemia | Recurrent Non-Hodgkin... and other conditions

United States
Washington University School of Medicine
Bristol-Myers Squibb; National Heart, Lung, and Blood Institute (NHLBI)

Completed

Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation

Lung Transplant Rejection | Antibody-mediated Rejection

United States
Weill Medical College of Cornell University
M.D. Anderson Cancer Center; Massachusetts General Hospital; Genentech, Inc.

Completed

Study of Venetoclax Plus DA-EPOCH-R for the Treatment of Aggressive B-Cell Lymphomas (V+DA-EPOCH-R)

Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma

United States
Northwestern University
Bristol-Myers Squibb; National Cancer Institute (NCI)

Suspended

Nivolumab and Combination Chemotherapy in Treating Participants With Diffuse Large B-Cell Lymphoma

B-Cell Non-Hodgkin Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | CD20 Positive | Aggressive Non-Hodgkin Lymphoma | Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma Unclassifiable | Intravascular Large B-Cell Lymphoma | T-Cell/Histiocyte-Rich...

United States
Nantes University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; Gilead Sciences

Completed

ImmunoTEP for Patients With Medullary Thyroid Carcinoma. (iTEP-CMT)

Medullary Thyroid Carcinoma

France
University of Washington
National Cancer Institute (NCI)

Completed

Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma

United States
Hoffmann-La Roche

Completed

A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis

Wegener's Granulomatosis or Microscopic Polyangiitis

India
United BioPharma

Completed

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UB-221 as an Add-on Therapy in CSU Patients

Urticaria Chronic

Taiwan
National Cancer Institute (NCI)

Terminated

Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination With the Src Family Kinase (SFK) Inhibitor Dasatinib in People With Embryonal and Alveolar Rhabdomyosarcoma

Rhabdomyosarcoma | Rhabdomyosarcoma, Alveolar | Rhabdomyosarcoma, Embryonal

United States
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas (ECHELON-2)

Non-Hodgkin Lymphoma | T-Cell Lymphoma | Anaplastic Large-Cell Lymphoma

United States, Korea, Republic of, Spain, United Kingdom, Taiwan, Czechia, Hungary, France, Israel, Germany, Italy, Denmark, Australia, Poland, Romania, Canada
Shanghai Biomabs Pharmaceutical Co., Ltd.

Completed

Anti-IgE Monoclonal Antibody Treatment in Patients With Allergic Asthma.

Asthma, Allergic

China
National Cancer Institute (NCI)

Completed

A Randomized Phase II Study of Cisplatin and Etoposide in Combination With Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMC-A12 for Patients With Extensive Stage

Extensive Stage Small Cell Lung Carcinoma | Recurrent Small Cell Lung Carcinoma

United States
M.D. Anderson Cancer Center
Genentech, Inc.

Completed

Fludarabine, Mitoxantrone, and Dexamethasone (FND) Plus Rituximab for Lymphoma Patients

Lymphoma

United States
Zhe Jiang Hisun Bioray Bio-pharmaceu tical Co.Ltd

Unknown

Comparison of Pharmacokinetics and Safety of HS632 and Xolair® With a Single Injection

Similarity of Pharmacokinetics and Safety

China
National Institute of Allergy and Infectious Diseases...

Terminated

Safety, Tolerability, and Immunogenicity of One Dose of NDV 3A Vaccine in People With STAT3-Mutated Hyper-IgE Syndrome

Autosomal-dominant Hyper-IgE Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Unknown

NK Cells in Cord Blood Transplantation

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia and other conditions

United States
University of California, San Francisco
University of Chicago

Withdrawn

Effects of Anti-IgE Antibody Omalizumab on Patients With Chronic Sinusitis

Chronic Sinusitis
University of Wisconsin, Madison
Bristol-Myers Squibb

Withdrawn

Belatacept in Kidney Transplantation of Moderately Sensitized Patients (BelatPilot)

End Stage Renal Disease | Antibody Mediated Rejection

United States
University of Washington
National Cancer Institute (NCI)

Withdrawn

Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride With Asparaginase in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Recurrent Adult Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | Recurrent B Lymphoblastic Lymphoma | Refractory B Lymphoblastic Lymphoma | B Lymphoblastic Lymphoma | Recurrent T Lymphoblastic Leukemia/Lymphoma | Refractory T Lymphoblastic Lymphoma | T Acute Lymphoblastic Leukemia | T...

United States
Cubist Pharmaceuticals LLC

Terminated

Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal Impairment (RENSE)

Renal Impairment | Complicated Skin and Skin Structure Infections | S. Aureus Bacteremia

United States
Northwestern University

Completed

Reduction of IgE Antibody in Human Allergic Subjects

Seasonal Allergic Rhinitis

United States
Nantes University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; Gilead Sciences

Completed

ImmunoTEP au 68-Ga- IMP-288 for Patients With a Recurrence of HER2 Negative Breast Carcinoma Expressing CEA (iTEPsein)

HER2 Negative Breast Carcinoma Expressing CEA

France
Johns Hopkins University

Completed

Induction Therapy Study in Live Donor Kidney Transplant Recipients With a Positive Crossmatch

Kidney Failure, Chronic

United States
National Institute of Allergy and Infectious Diseases...

Completed

Omalizumab to Treat Eosinophilic Gastroenteritis

Gastroenteritis

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.; Immune Tolerance Network (ITN)

Completed

Rituximab for the Treatment of Wegener's Granulomatosis and Microscopic Polyangiitis (RAVE)

Vasculitis | Wegener's Granulomatosis | Microscopic Polyangiitis

United States, Netherlands
National Institute of Allergy and Infectious Diseases...
Inner-City Asthma Consortium

Completed

Inner-City Anti-IgE Therapy for Asthma (ICATA)

Asthma

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of ChimeriVax-WN02 West Nile Vaccine in Healthy Adults

West Nile Fever

United States
Igenica Biotherapeutics, Inc.

Completed

A Phase I Study of IGN523 in Subjects With Relapsed or Refractory AML

Acute Myeloid Leukemia | Acute Myelogenous Leukemia

United States
Shanghai Zhangjiang Biotechnology Limited Company

Completed

Safety and Efficacy Study of Omalizumab to Treat Allergic Asthma (AA007)

Allergic Asthma

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma

Childhood Diffuse Large Cell Lymphoma | Childhood Immunoblastic Large Cell Lymphoma | Childhood Burkitt Lymphoma | Untreated Childhood Acute Lymphoblastic Leukemia | Stage I Childhood Large Cell Lymphoma | Stage I Childhood Small Noncleaved Cell Lymphoma | Stage II Childhood Large Cell Lymphoma | Stage II Childhood Small Noncleaved Cell Lymphoma and other conditions

United States
National Taiwan University Hospital

Completed

The Effect of Anti-CεmX on IgE Production (h4B12PBMC)

Atopic Dermatitis

Taiwan
University of Chicago
Genentech, Inc.; Novartis Pharmaceuticals

Completed

Xolair in Patients With Chronic Sinusitis

Sinusitis

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Stage III or Stage IV Low-Grade Non-Hodgkin's Lymphoma

Stage III Grade 1 Follicular Lymphoma | Stage III Grade 2 Follicular Lymphoma | Stage III Grade 3 Follicular Lymphoma | Stage III Small Lymphocytic Lymphoma | Stage IV Grade 1 Follicular Lymphoma | Stage IV Grade 2 Follicular Lymphoma | Stage IV Grade 3 Follicular Lymphoma | Stage IV Small Lymphocytic...

United States
Federal University of Uberlandia
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Sublingual Immunotherapy in Children With Allergic Rhinitis (SLIT)

Allergic Rhinitis

Brazil

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