Search clinical trials for: Immunomodulatory agent

Total 188647 results

Ain Shams University

Recruiting

Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS

Inflammatory Response | Preterm Birth | Premature Lungs | Neonatal Respiratory Distress Syndrome | Neutrophil Extracellular Trap Formation

Egypt
University Hospital, Bordeaux

Not yet recruiting

Evaluation of the Efficacy of Immunomodulatory Therapy in Case of Psychiatric Disorders With Proven Dysimmunity. (TIM-DePisT)

Mental Disorder

France
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Interferon Alfa Therapy Based on Th17 Profile in Membranous Nephropathy (ALPHAGEM)

Membranous Nephropathy

France
Cheng LuFeng,Principal Investigator
First Affiliated Hospital of Xinjiang Medical University

Not yet recruiting

Clinical Study on the Immunomodulatory Effect of Eprolidone on Patients With Chronic Heart Failure

Chronic Heart Failure Patients
Fudan University

Recruiting

Famitinib in Combination With Camrelizumab and TPC in The First-line Treatment of Immunomodulatory Locally Advanced or Metastatic TNBC.

Triple-Negative Breast Cancer

China
Massachusetts General Hospital

Recruiting

Immunomodulatory Effects of PCSK9 Inhibition (INSPIRAR)

Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Stroke | Atherosclerosis | Transient Ischemic Attack | Carotid Artery Diseases | Carotid Atherosclerosis | Cerebrovascular Accident | Atherosclerotic Cardiovascular Disease | Vascular Calcification | Heart Attack | Vascular Disease, Peripheral | Arterial... and other conditions

United States
Lucie Heinzerling

Recruiting

Treatment of Immune-related Adverse Events Refractory to Standard Therapy and Associated Changes in Immunophenotype (PRIA)

Immune-related Adverse Event

Germany
Region Örebro County

Recruiting

A Randomized Controlled Trial With Rituximab for Psychotic Disorder in Adults (RCT-RITS)

Schizophrenia Spectrum and Other Psychotic Disorders

Sweden
Angelica Lindén Hirschberg

Recruiting

Immunomodulatory Therapy in Women With Autoimmune Premature Ovarian Insufficiency

Autoimmune Diseases | Premature Ovarian Insufficiency

Sweden
Universidade Federal do Rio de Janeiro

Recruiting

Immunomodulatory Effect of Dexmedetomidine as an Adjuvant Drug in Laparoscopic Cholecystectomies

Physiological Effects of Drugs

Brazil
Centre Hospitalier St Anne
For Drug Consulting

Recruiting

Therapeutic Evaluation of Low-dose IL-2-based Immunomodulatory Approach in Patients With Early AD (IL-2-AD)

Alzheimer Disease

France
National Cancer Institute (NCI)

Recruiting

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

Burkitt Lymphoma | Plasmablastic Lymphoma | Non-Hodgkin Lymphoma | Diffuse Large Cell Lymphoma | B-Cell Neoplasm

United States
H. Lee Moffitt Cancer Center and Research Institute
Adaptive Biotechnologies

Recruiting

Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant

Multiple Myeloma

United States
Sun Yat-sen University

Recruiting

Corticosteroid Combining Noncorticosteroid Systemic Immunomodulatory Therapy in VKH

Vogt Koyanagi Harada Disease (VKH)

China
Alpha Tau Medical LTD.

Recruiting

A Safety and Efficacy Study for Combinational Treatment of DaRT and Check Point Inhibitor for Recurrent Unresectable or mHNSCC

Skin Cancer | Head and Neck Squamous Cell Carcinoma | Metastatic Head-and-neck Squamous-cell Carcinoma

Israel
Phoenicis Therapeutics

Recruiting

Trial to Determine the Immunomodulatory Activity of PTM-001 in Patients With Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
National Cancer Institute (NCI)
Janssen Scientific Affairs, LLC

Recruiting

Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

Multiple Myeloma

United States
Alexandria University

Recruiting

Immunomodulatory Effects of Dexmedetomidine Infusion

Major Abdominal Surgery

Egypt
University of Crete
University Hospital of Crete

Recruiting

Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

Postoperative Pain | Anesthesia | Opioid Use | Interleukin 6 | Elective Surgical Procedures | Abdominal Aortic Aneurysm Without Rupture | Vascular Surgical Procedure | Immunomodulators

Greece
Assistance Publique - Hôpitaux de Paris

Recruiting

Immunomodulatory Profile of Dexmedetomidine Sedation in Patients Recovering After ARDS Covid-19 (DEXDO-COVID)

SARS-CoV 2

France
Janssen Biotech, Inc.

Active, not recruiting

A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease (DEVELOP)

Inflammatory Bowel Diseases | Crohn's Disease | Ulcerative Colitis | Indeterminate Colitis

United States, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Cryoablation for the Treatment of Metastatic Cancer

Metastatic Malignant Neoplasm

United States
Lin Chen

Completed

Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes

Sepsis | Cytokine Storm | Sympathetic Nervous System Diseases | Catecholamine; Overproduction | Immunologic Paralysis | Lymphocyte Disorder T | Beta-Blocker

China
National Cancer Institute (NCI)

Active, not recruiting

Carfilzomib, Lenalidomide, and Dexamethasone for Smoldering Multiple Myeloma

Multiple Myeloma

United States
Janssen Research & Development, LLC

Completed

A Study of JNJ-54767414 (HuMax CD38) (Anti-CD38 Monoclonal Antibody) in Combination With Backbone Treatments for the Treatment of Patients With Multiple Myeloma

Multiple Myeloma

United States, France, Spain
Amgen

Completed

Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus (SLE)

United States, Korea, Republic of, Australia, Spain, Hungary, Bulgaria, Italy, Mexico, Germany, Japan, France, Greece, Czechia, Argentina, Portugal, Poland, Russian Federation, Hong Kong, Canada
Pfizer

Completed

PF-06863135 As Single Agent And In Combination With Immunomodulatory Agents In Relapse/Refractory Multiple Myeloma

Multiple Myeloma

Canada, United States
Mayo Clinic

Active, not recruiting

Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (Dexamethasone) for the Treatment of Multiple Myeloma

Plasma Cell Myeloma | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Smoldering Plasma Cell Myeloma

United States
National Cancer Institute (NCI)

Active, not recruiting

Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies

Cutaneous T-Cell Lymphoma | Peripheral T-Cell Lymphoma | Mature T-cell Malignancies | Relapsed/ Refractory T-cell Malignancies

United States
Theodor Bilharz Research Institute

Completed

Synergistic Immunomodulatory Effect of Synbiotics Pre and Postoperative Resection of Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic Ductal Adenocarcinoma

Egypt
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide Combined With Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-associated Large Cell Lymphoma

Primary Effusion Lymphoma | B-Cell Neoplasm

United States
University Hospital, Caen

Completed

Identification of Immunomodulators Associated With Atrial Fibrillation Reporting: Analysis of the WHO Pharmacovigilance Database

Atrial Fibrillation

France
Celgene

Active, not recruiting

Study of ACY-241 Alone and in Combination With Pomalidomide and Dexamethasone in Multiple Myeloma

Multiple Myeloma

United States, France, Spain, Germany, Greece
AVM Biotechnology Inc

Available

Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients

Cancer | Breast Cancer | Glioblastoma | Gastric Cancer | Pancreatic Cancer | Hodgkin Lymphoma | Ovarian Cancer | Prostate Cancer | Acute Leukemia | Non-hodgkin Lymphoma | Squamous Cell Carcinoma | Tumor, Solid | Tumor, Brain | Spindle Cell Sarcoma
Tunis University

Completed

Erythromycin in Septic Patients: Immunomodulatory Role and Clinical Impact

Sepsis | Septic Shock | Immunoinflammatory Response

Tunisia
The First Affiliated Hospital of Soochow University

Enrolling by invitation

GZL Sequential CD19/CD22 CAR-T in Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

China
Sociedad Argentina de Reumatologia

Completed

Argentinian Registry of Patients With Rheumatic Diseases and COVID-19 Infection (SAR-COVID)

Rheumatic Diseases

Argentina
InDex Pharmaceuticals

Completed

The Efficacy and Safety of Cobitolimod (Kappaproct®) in Chronic Active Treatment Refractory Ulcerative Colitis Patients (COLLECT)

Colitis, Ulcerative

Czechia, France, Germany, Hungary, Italy, Poland, United Kingdom
University College, London
Cancer Research UK; Celgene

Active, not recruiting

Trial of Immunomodulatory Therapy in High Risk Solitary Bone Plasmacytoma (IDRIS)

Plasmacytoma

United Kingdom
The University of Hong Kong

Suspended

Immunomodulatory Effect of Macrolides in Naturally Occurring Influenza Virus Infections in the Community

Influenza, Human

Hong Kong
Johnson & Johnson Private Limited

Completed

A Study of DARZALEX (Daratumumab) In Indian Participants With Relapsed and Refractory Multiple Myeloma, Whose Prior Therapy Included a Proteasome Inhibitor and an Immunomodulatory Agent

Multiple Myeloma

India
Centre of Postgraduate Medical Education

Completed

Azathioprine Linked With Impaired Intestinal Epithelial Postoperative Regeneration in Crohn's Disease

Inflammatory Bowel Diseases
TG Therapeutics, Inc.

Terminated

Ublituximab in Combination With Lenalidomide in Patients With B-Cell Lymphoid Malignancies

Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Waldenstrom's Macroglobulinemia | Non-Hodgkins Lymphoma | Small Lymphocytic Lymphoma | B-cell Lymphomas

United States
Bezmialem Vakif University
Albayraklar Foundation

Completed

Immunomodulatory and Preventive Effects of Olive Leaf Tea Against COVID-19

Immunomodulation

Turkey
Oxford University Hospitals NHS Trust
University of Warwick; University of Birmingham; Janssen-Cilag Ltd.; Bloodwise

Completed

Optimising Renal Outcome in Myeloma Renal Failure (OPTIMAL)

Multiple Myeloma | Chronic Kidney Disease

United Kingdom
Fudan University

Active, not recruiting

A Trial of Camrelizumab in Combination With Nab-paclitaxel and Famitinib as a First Line Treatment in Patients With Unresectable Locally Advanced or Metastatic Immunomodulatory Triple Negative Breast Cancer(FUTURE-C-PLUS)

Triple-Negative Breast Cancer

China
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Clinical Trial To Evaluate the Toxicity, Antiviral and Immunomodulatory Effects of a Range of Doses of Ampligen in HIV-Infected Subjects

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Umbrella Study for HIV Infected Adults Enrolled in NIAID-Funded Interleukin-2 Studies

HIV Infections

United States
ImmunityBio, Inc.

Active, not recruiting

Study of the Safety of Therapeutic Treatment With an Immunomodulatory Agent (N-803) in Adults With COVID-19

COVID-19

United States
Assiut University

Completed

Vitamin D as a Key Player in Rheumatoid Arthritis

the Immunomodulatory Effect

Egypt

Search clinical trials for: Immunomodulatory agent

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bosnia & Herzegovina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations