Search clinical trials for: Insulin Signaling

Total 8201 results

University of Alabama at Birmingham

Not yet recruiting

VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway (VITAL-IMPACT)

Cardiovascular Diseases | Obesity | Insulin Sensitivity/Resistance | Metabolic Disease | Energy Expenditure | Metabolism

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Recruiting

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

Obesity | Muscle Weakness | Insulin Resistance | Adiposity | Insulin Sensitivity

United States
University Hospital, Montpellier

Recruiting

Immune Activation as a Cause of Insulin Resistance in Adults Living With HIV-1 on Effective Antiretroviral Therapy (MetACTIVIH)

HIV Infections

France
Adrian Vella
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

A Dose-response Study Examining the Contribution of GLP-1 Receptor Signaling to Glucagon-stimulated Insulin Secretion

Healthy

United States
Tanta University

Completed

Role of Nitazoxanide and Escitalopram in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Egypt
Wayne State University

Withdrawn

Insulin Signaling in Skeletal Muscle

Insulin Sensitivity
National Institute of Diabetes and Digestive and...

Completed

Fat Cell Size in Insulin Resistance

Obesity

United States
The University of Texas Health Science Center at...

Terminated

The Effect of TLR4 Inhibition in Obese and Type 2 Diabetic Subjects (Eritoran2)

Insulin Sensitivity

United States
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Study of Dapagliflozin on Mitochondrial Dysfunction and Impaired Insulin Signaling/Action (DAPA MITO)

Insulin Sensitivity | Multiple Mitochondrial Dysfunctions Syndrome

United States
The University of Texas Health Science Center at...

Completed

The Role of TLR4 on Lipid-induced Insulin Resistance (Eritoran1)

Insulin Sensitivity

United States
Oregon State University

Completed

Exercise and Insulin Signaling in Human Skeletal Muscle

Obesity | Sedentary Lifestyle | Insulin Sensitivity

United States
Brigham and Women's Hospital

Completed

Free Fatty Acids and Vascular Function in Subjects With Diabetes

Type 2 Diabetes Mellitus

United States
Washington University School of Medicine
American Diabetes Association

Completed

The Role of Cholinergic Signaling for Mediating the Effects of GIP and/or Xenin-25 on Insulin Secretion

Pre-diabetes

United States
University of Aarhus

Completed

Substrate Metabolism, Growth Hormone Signaling (GH), and Insulin Sensitivity During GH and Ketone Bodies Infusion

Healthy

Denmark
Amsterdam UMC, location VUmc
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Microvascular Dysfunction and the Development of Whole-body Insulin Resistance (DESIRE)

Obesity | Insulin Resistance | Type 2 Diabetes

Netherlands
Vanderbilt University

Completed

Dopamine and Insulin Resistance

Obesity

United States
Tehran University of Medical Sciences

Completed

A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome

Coronary Artery Disease | Metabolic Syndrome

Iran, Islamic Republic of
Vanderbilt University Medical Center

Completed

Effect of Prolonged PDE-5 Inhibition on Insulin Signaling in Skeletal Muscle.

Metabolic Syndrome

United States
University of Aarhus

Completed

Substrate Metabolism, Growth Hormone Signaling, and Insulin Sensitivity During Fasting

Healthy

Denmark
University of Aarhus
Aarhus University Hospital

Completed

The Relationship Between Body Composition and Growth Hormone, SIRT Signaling, Protein Turnover and Insulin Sensitivity

Healthy

Denmark
University of Aarhus
Novo Nordisk A/S; Aarhus University Hospital

Completed

Metabolic Studies- Interactions Between GH and Insulin in GHDA

Insulin Resistance

Denmark
Medical Center Alkmaar

Unknown

Dipeptide Alanyl Glutamine and Postoperative Insulin Resistance in Colon Carcinoma Patients (AIRCo)

Colon Carcinoma

Netherlands
University of Aarhus
MR Research Center, Skejby Sygehus, Brendstrupgaardsvej 100, 8200 Aarhus N

Terminated

Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidism

Hypothyroidism

Denmark
Aarhus University Hospital

Completed

Peripheral Effects of Endotoxin on Insulin Resistance

Healthy

Denmark
University of Aarhus
Aarhus University Hospital

Completed

Effect of Growth Hormone on Insulin Signaling in Muscle Tissue

Insulin Resistance

Denmark
Shanghai Changzheng Hospital

Completed

The Effect of the Preoperative Oral Carbohydrate Attenuating Immediate Postoperative Insulin Resistance on PI3K Dependent Signaling Pathway

Colorectal Disease

China
University of Aarhus

Completed

Growth Hormone Signaling in Vivo in Humans

Intracellular Signaling Peptides and Proteins

Denmark
Laval University
Canadian Institutes of Health Research (CIHR)

Completed

Dietary Fish Protein in Subjects With Insulin Resistance

Insulin Resistance | Type 2 Diabetes

Canada
Central South University

Not yet recruiting

Investigating the Insulin Resistance in Individuals With Type 2 Diabetes

Type 2 Diabetes

China
Tandem Diabetes Care, Inc.

Recruiting

Tandem Freedom - Feasibility Trial 1

Diabetes Mellitus, Type 1

New Zealand
Dr R Viswa Chandra

Recruiting

Efficacy of Insulin Like Growth Factor-1(IGF-1) on Bone Regeneration in Intrabony Defects : A Clinico-radiograph Study

Intrabony Periodontal Defect

India
Khyber Medical University Peshawar

Recruiting

Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet

Inflammation | Obesity | Insulin Resistance | Dyslipidemias | Advance Glycation

Pakistan
Xie Kangjie

Recruiting

Predictive Effect of TGF-β Combined With INS-PI3K-AKT Signaling Pathway Related Proteins (ADNP, MAP6, Pgc-1α) for POD on Diabetes Patients

Diabetes | Postoperative Delirium

China
Mayo Clinic

Not yet recruiting

Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes

PreDiabetes

United States
Mayo Clinic

Not yet recruiting

Insulin and Insulin Pulses During Fasting

PreDiabetes

United States
McGill University

Recruiting

Accuracy of a Continuous Ketone Monitoring (CKM) System in Individuals With Type 1 Diabetes on Insulin Pump Therapy. (CKM 1)

type1diabetes

Canada
Oregon Health and Science University

Not yet recruiting

Two Way Crossover Closed Loop Study Insulin vs Insulin and Pramlintide

Type 1 Diabetes
Fundación para la Investigación del Hospital Clínico...
Novo Nordisk A/S

Not yet recruiting

Insulin Injection Practices in Spain

Diabetes

Spain
Thomas Jefferson University
University of Rochester

Not yet recruiting

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 1)

Pregnancy Related | Gestational Diabetes

United States
Emory University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Automated Insulin Delivery for Inpatients With Dysglycemia (AIDING)

Type 1 Diabetes | Type 2 Diabetes

United States
University Hospital, Gentofte, Copenhagen

Recruiting

The Glucagonotropic Effects of Glucose-dependent Insulinotropic Polypeptide and Alanine in Healthy Individuals (GIPALANIN)

Effect of iv Administration of GIP and Alanine

Denmark
Thomas Jefferson University
University of Rochester

Not yet recruiting

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2) (START2)

Pregnancy Related | Gestational Diabetes

United States
Seoul National University Hospital
Medtronic

Recruiting

Effects of AHCL Insulin Pump on Glycemic Control and Psychosocial Outcomes in Pediatric Patients With Type 1 Diabetes

Type 1 Diabetes

Korea, Republic of
Fundación para la Investigación del Hospital Clínico...

Not yet recruiting

Benefits of Smart Pens in Type 1 Diabetes

Type 1 Diabetes

Spain
Children's Hospital of Fudan University

Not yet recruiting

High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children

Cardiovascular Syndrome, Metabolic
Brooklyn Clinical Research

Not yet recruiting

Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility (SWIFT-CORE-101)

Cardiovascular Diseases | Obesity | Metabolic Syndrome | PreDiabetes | Diabetes Type 2

United States
Jordan Collaborating Cardiology Group
Cardiovascular Academy; The Association of Jordanian Medical Laboratory Specialists...

Not yet recruiting

The Cardiovascular-Renal-Metabolic (CRM) Syndrome Survey in Jordan (JoCRMSSurvey)

Cardiovascular-renal-metabolic Syndrome

Jordan
University Medical Center, Kazakhstan
Nazarbayev University; Astana Medical University; Ministry of Science and Higher... and other collaborators

Recruiting

Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome

Metabolic Syndrome

Kazakhstan
Peking University People's Hospital

Not yet recruiting

The Efficacy and Safety of Insulin Degludec/Liraglutide Combination (IDegLira) in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2
G2e Co., Ltd

Recruiting

DIA:CONN P8(Smart Insulin Pen) Study in Diabetes Patients

Diabetes Mellitus

Korea, Republic of

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