Search clinical trials for: Liver metabolite

Total 18611 results

University of Liverpool
Liverpool University Hospitals NHS Foundation Trust; Liverpool Hope University

Recruiting

Multivariate Biomarker Study for Sarcopenia in Heart Failure

Heart Failure | Body Weight | Muscle Weakness | Frailty | Sarcopenia

United Kingdom
Nanfang Hospital of Southern Medical University

Recruiting

A Bidirectional Study in Exploring the Dynamic Changes of Plasma and Urine Metabolites of Liver Cancer

Liver Cirrhosis | Hepatitis | Fatty Liver | Liver Cancer

China
Massachusetts General Hospital
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER (COMMENCER)

Colorectal Cancer | Fibrosis, Liver | Stenosis | Gastrointestinal Microbiome | Coffee | Ultrasound Elastography | Proton Magnetic Resonance Spectroscopy

United States
Sinew Pharma Inc.

Recruiting

A Partial Randomized, Single-blind or Open-label, Dose-escalation With Multiple-dose Design Study to Evaluate the Pharmacokinetics of Acetaminophen and Its Toxic Metabolites With Panadol® and SafeTynadol® in Healthy Volunteers

Hepatitis | Pharmacology

Taiwan
Hepatopancreatobiliary Surgery Institute of Gansu...
Lishui Country People's Hospital; The Third People's Hospital of Taiyuan; Shulan... and other collaborators

Recruiting

Non-invasive Diagnosis of Portal Hypertension in Cirrhosis Based on Metabolomics Technology

Portal Hypertension | Cirrhosis, Liver

China
Wuhan Union Hospital, China

Recruiting

Alterations of Gut Microbiota and Metabolites in ALD Patients

Gut Microbiota | Liver Disease; Alcohol-Related

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Study of TACE Combined With Camrelizumab Plus Rivoceranib (Apatinib) in Patients With Incurable Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Rennes University Hospital

Recruiting

Dosage of Tacrolimus Metabolites in Blood and Bile for Prediction of Its Side Effects in Liver Transplant Recipients (STABILE 2)

Blood Concentration of Tacrolimus Metabolites

France
National Cancer Centre, Singapore
Nanyang Technological University; Duke-NUS Graduate Medical School; MiRXES Pte... and other collaborators

Recruiting

Prospective Cohort Study of Changes in Circulatory MicroRNA of Resected Hepatocellular Carcinoma (PROSECT)

Hepatocellular Carcinoma

Singapore
National Cancer Centre, Singapore
Nanyang Technological University; Duke-NUS Graduate Medical School; MiRXES Pte... and other collaborators

Recruiting

Early Detection of Hepatocellular Carcinoma in a High-risk Prospective Cohort (ELEGANCE)

Liver Diseases

Singapore
Eisai Co., Ltd.

Recruiting

Study to Evaluate the Pharmacokinetics (PK) of E7090 (Herein Referred to as Tasurgratinib) and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants

Hepatic Impairment

Japan
Nanfang Hospital, Southern Medical University

Recruiting

Evaluating the Association Between Sphingolipid Metabolites and Post-hepatectomy Liver Failure

Post-hepatectomy Liver Failure

China
SWOG Cancer Research Network
National Cancer Institute (NCI)

Terminated

Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors

Malignant Solid Neoplasm | Hepatitis B Infection

United States, Guam
Kyowa Kirin, Inc.

Completed

Single-dose Study to Investigate the Plasma PK of KW-6356 and Its Major Metabolite

Hepatic Impairment

United States
Ewha Womans University Mokdong Hospital

Completed

Nonalcoholic Fatty Liver Disease - Intermittent Calorie Restriction (FLICR) Study

Nonalcoholic Steatohepatitis | Nonalcoholic Fatty Liver

Korea, Republic of
The Affiliated Hospital of Qingdao University

Completed

Metabonomic of Patients With Hepatitis B Cirrhosis Complicated With Sarcopenia.

Sarcopenia

China
Acerta Pharma BV
AstraZeneca

Completed

Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite

Hepatic Insufficiency | Healthy Subjects | Hepatic Impairment

United States
Osijek University Hospital
Josip Juraj Strossmayer University of Osijek

Completed

Metabolites of Tramadol in the Postoperative Surgical Patients (METRAS)

Respiratory Failure | Renal Failure | Abdominal Surgery | Liver Dysfunction | Multiorgan Failure

Croatia
Rockefeller University
National Institutes of Health (NIH); Weill Medical College of Cornell University

Completed

Effects of Dietary Fructose on Gut Microbiota and Fecal Metabolites in Obese Men and Postmenopausal Women: A Pilot Study

Obesity | Non-Alcoholic Fatty Liver Disease

United States
Eisai Inc.
Purdue Pharma LP

Completed

Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

United States
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Sun Yat-Sen Memorial Hospital...

Unknown

To Explore the Diversity of Intestinal Flora in Patients With Advanced HCC Combin ed With Anti-PD-1 and Targeted Drug Therapy and the Correlation Between Metabolites and Therapeutic Effect

Advanced Hepatocellular Carcinoma
Allergan

Completed

Impact of Severe Hepatic Impairment on Pharmacokinetics of Cenicriviroc and Its Metabolites

Hepatic Impairment

United States
University of Helsinki

Completed

Randomised Open-label Multicenter Study Evaluating Ciprofloxacin in Severe Alcoholic Hepatitis

Alcoholic Hepatitis | Alcoholic Cirrhosis

Finland
Kirby Institute
Bristol-Myers Squibb

Withdrawn

Impact of HCV Treatment on Neurocognitive Functions and Brain Metabolism (HEPCOG-II)

Hepatitis C, Chronic

Australia
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Pharmacokinetics of PCI-32765 in Participants With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States
Beijing 302 Hospital

Recruiting

Sequential Combination Therapy With PD-1 Antibody and Peg-IFNα in CHB Patients

Chronic Hepatitis B

China
University Hospital Ostrava

Recruiting

Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors

Hepatitis E

Czechia
RenJi Hospital

Recruiting

Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH)

Familial Hypercholesterolemia

China
Youssef Khalifa Fakher Botros

Not yet recruiting

Risk Factors and Frequency of Acute Idiopathic Hepatitis in Children at Assiut Children Hospital

Risk Factors and Frequency of Acute Idiopathic Hepatitis in Children at Assiut Children Hospital
University of California, Davis

Not yet recruiting

NeuroFLiPP: Parametric PET of Neuroinflammation in Fatty Liver Disease

Positron Emission Tomography

United States
AstraZeneca

Recruiting

Patient Characteristics, Treatment Patterns and Outcomes of Patients Enrolled in the Tezepelumab Patient Access Programme; a Retrospective, Observational Medical Chart Review Conducted in UK Severe Asthma Centres (TPAP)

Severe Asthma

United Kingdom
Qilu Hospital of Shandong University

Recruiting

Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection

Carcinoma, Hepatocellular

China
Elizabeth C. Verna
ITB-Med LLC

Not yet recruiting

SIPLIZUMAB in AILD and LT (SET-SAIL)

Autoimmune Liver Disease | Primary Sclerosing Cholangitis | Autoimmune Hepatitis | Cirrhosis, Liver | Liver Transplant Disorder | End Stage Liver DIsease

United States
Liverpool Heart and Chest Hospital NHS Foundation...
Biolife LLC

Not yet recruiting

Statseal® for Central Venous Catheter Insertion Sites in Critical Care (SCENIC)

Vascular Access | Critical Care | Central Venous Catheter | Central Line | Hemostatic

United Kingdom
Sohag University

Not yet recruiting

Assessment the Diagnostic Value of Pro-Neurotensin as a Serum Biomarker in MASLD

Steatosis of Liver
Bayer

Not yet recruiting

A Study to Learn More About How Well BAY 2927088 Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Human Epidermal Growth Factor Receptor 2 (HER2)

Advanced Non-small Cell Lung Cancer | HER2 Mutation

United States, Korea, Republic of, Belgium, China, Japan, Taiwan, Denmark, Germany, Israel, Italy, United Kingdom, Bulgaria, Portugal, Switzerland, Greece, Turkey, Sweden, France, Singapore, Mexico, Spain, Netherlands, Poland, Brazil, A... and more
Regeneron Pharmaceuticals

Not yet recruiting

A First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy Adults

Healthy Volunteers
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Study to Evaluate the Efficacy of TQA3038 Injection in Patients With Chronic Hepatitis B

Hepatitis B, Chronic

China
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Non-invasive Detection of Volatile Metabolites in Parkinson's Disease (PANORAMA)

Parkinson Disease

United Kingdom
Istanbul Kent University

Not yet recruiting

Aronia and Non-alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease
Anhui Provincial Hospital
First Affiliated Hospital of Wannan Medical College

Recruiting

Local Liver Treatment for Multi-organ Colorectal Cancer Metastases

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Multi-organ Metastatic Colorectal Cancer

China
Zhujiang Hospital

Not yet recruiting

Compare the Accuracy of ctDNA-MRD and MVI Result in Predicting Postoperative Recurrence of Hepatocellular Carcinoma

Recurrence | Surgery | Hepatocellular Carcinoma Resectable

China
Zhujiang Hospital

Recruiting

Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD (HHTN)

Nonalcoholic Fatty Liver Disease | Type2 Diabetes Mellitus

China
Million Marker Wellness, Inc.
University of Nevada, Reno; Renown Health

Not yet recruiting

A Personalized Biomonitoring and Report-back Intervention to Reduce Exposure to Endocrine Disrupting Chemicals (REED)

Environmental Exposure
Chinese University of Hong Kong
University of Palermo; University of Malaya; Singapore General Hospital; University... and other collaborators

Not yet recruiting

Non-selective Beta-blocker in Compensated Advanced Chronic Liver Disease (BB_cACLD)

Portal Hypertension | Advanced Chronic Liver Disease | Hepatic Decompensation
Zhongda Hospital

Recruiting

Efficacy and Safety of 90Y Microsphere Combined With FOLFIRI and Bevacizumab in Second-line Treatment of CRLM

Colorectal Cancer Metastatic

China
Shanghai Zhongshan Hospital

Recruiting

Effects of Growth Hormone Therapy on Metabolic Function in Fatty Liver Post-Pituitary Adenoma Surgery

Growth Hormone Treatment

China
Imperial College London
University of Central Lancashire; University of Nottingham; Cancer Research UK; University of Birmingham and other collaborators

Recruiting

Cancer Loyalty Card Study 2 (CLOCS-2) ((CLOCS-2))

Stomach Cancer | Pancreatic Cancer | Ovarian Cancer | Vulvar Cancer | Bladder Cancer | Endometrial Cancer | Colon Cancer | Liver Cancer | Oesophageal Cancer | Uterine Cancer

United Kingdom
Hopital Montfort

Not yet recruiting

Acceptability and Feasibility of a New Approach to Engage Patients With Steatotic Liver Disease in Physical Activity

Liver Steatosis | MASLD | MASH

Search clinical trials for: Liver metabolite

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